KEGG ORTHOLOGY: K04889

ORTHOLOGY: K04889

Entry

K04889                      KO

Symbol

KCNC3, KV3.3

Name

potassium voltage-gated channel Shaw-related subfamily C member 3

Pathway

map05017

Spinocerebellar ataxia

Disease

H00063

Spinocerebellar ataxia (SCA)

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K04889  KCNC3, KV3.3; potassium voltage-gated channel Shaw-related subfamily C member 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K04889  KCNC3, KV3.3; potassium voltage-gated channel Shaw-related subfamily C member 3
Ion channels [BR:ko04040]
Voltage-gated cation channels
  Potassium channel, voltage-gated (Kv)
   K04889  KCNC3, KV3.3; potassium voltage-gated channel Shaw-related subfamily C member 3

Other DBs

GO:

0005251

TC:	1.A.1.2.13

Genes

HSA:	3748(KCNC3)

PTR:	100611156(KCNC3)

PPS:	100979004(KCNC3)

GGO:	101137465(KCNC3)

PON:	100454778(KCNC3)

PPYG:

129020487(KCNC3)

NLE:	100589403 115836979

HMH:	116464336 116464343

SSYN:

129459621(KCNC3)

MCC:	719568(KCNC3)

MCF:	102115741(KCNC3)

MTHB:

126943099

MNI:	105497340(KCNC3)

CSAB:

103235074(KCNC3)

CATY:

105595320(KCNC3)

PANU:

101025971(KCNC3)

TGE:	112612506(KCNC3)

MLEU:

105529005(KCNC3)

RRO:	104667276(KCNC3)

RBB:	108525920 108535768(KCNC3)

TFN:	117091624(KCNC3)

PTEH:

111520046(KCNC3)

CANG:

105514852(KCNC3)

CJC:	100394945(KCNC3)

SBQ:	101045751(KCNC3)

CIMI:

108292000(KCNC3)

ANAN:

105724200(KCNC3)

MMUR:

105865536(KCNC3)

LCAT:

123623786(KCNC3)

ERUF:

138374591(KCNC3)

PCOQ:

105809335(KCNC3)

OGA:	100942146(KCNC3)

MMU:	16504(Kcnc3)

MCAL:

110298278(Kcnc3)

MPAH:

110326280(Kcnc3)

RNO:	117101(Kcnc3)

MCOC:

116102139(Kcnc3)

ANU:	117713841(Kcnc3)

ASYL:

127669886(Kcnc3)

MUN:	110546818(Kcnc3)

CGE:	100773356(Kcnc3)

MAUA:

101833203(Kcnc3)

PROB:

127213909(Kcnc3)

PLEU:

114684335(Kcnc3)

PMAV:

102909727(Kcnc3)

MORG:

121446124(Kcnc3)

MFOT:

126488091

AAMP:

119802784(Kcnc3)

CNL:	130868939(Kcnc3)

NGI:	103743691(Kcnc3)

HGL:	101701612(Kcnc3)

CPOC:

100720775(Kcnc3)

CCAN:

109683842 109683855(Kcnc3) 109699078

DORD:

105994160(Kcnc3)

DSP:	122125611(Kcnc3)

DMER:

138812762(Kcnc3)

PLOP:

125338512(Kcnc3)

NCAR:

124966603

MMMA:

107151556(Kcnc3)

ITI:	101977159(Kcnc3)

OPI:	101527261(KCNC3)

OCZ:	121155135(KCNC3)

TUP:	102483980(KCNC3)

GVR:	103593097(KCNC3)

CFA:	102156059(KCNC3)

CLUD:

112645110(KCNC3)

VVP:	112931510(KCNC3)

VLG:	121485403(KCNC3)

NPO:	129500853(KCNC3)

AML:	100464065(KCNC3)

UMR:	103657271(KCNC3)

UAH:	113247246(KCNC3)

UAR:	123777968(KCNC3)

ELK:

111160726

LLV:

125090000

MPUF:

101677915(KCNC3)

MNP:	132005558(KCNC3)

MLK:	131817544(KCNC3)

NVS:	122911792(KCNC3)

ORO:	101369249(KCNC3)

EJU:	114199546(KCNC3)

ZCA:	113935369(KCNC3)

MLX:	117998269(KCNC3)

NSU:	110579680(KCNC3)

LWW:	102741641(KCNC3)

FCA:	101099418(KCNC3)

PYU:	121018941(KCNC3)

PCOO:

112850823(KCNC3)

PBG:	122493825(KCNC3)

PVIV:

125153812(KCNC3)

LRUF:

124510880

LGF:	123578701(KCNC3)

AJU:

106983128

PTG:	102972405(KCNC3)

PPAD:

109253016(KCNC3)

PUC:

125915921

PLEZ:

122208371(KCNC3)

HHV:	120239798(KCNC3)

BTA:	617852(KCNC3)

BOM:	102266501(KCNC3)

BIU:	109571930(KCNC3)

BBUB:

102414120(KCNC3)

BKE:	129631721(KCNC3)

BBIS:

104995745(KCNC3)

CHX:	102188248(KCNC3)

OAS:	101116251(KCNC3)

BTAX:

128063356(KCNC3)

CSUM:

138096343(KCNC3)

ODA:	120871950(KCNC3)

CCAD:

122421124(KCNC3)

MREE:

136161568(KCNC3)

OVR:	110133136(KCNC3)

MBEZ:

129546434(KCNC3)

SSC:	100511263(KCNC3)

CFR:	106731147(KCNC3)

CBAI:

105062773(KCNC3)

CDK:	105100232(KCNC3)

VPC:	102545311(KCNC3)

BACU:

103001204(KCNC3)

BMUS:

118885073(KCNC3)

LVE:	103069205(KCNC3)

OOR:	101288117(KCNC3)

LALB:

132510448(KCNC3)

GMF:	115849065(KCNC3)

DDP:	132416371(KCNC3)

DLE:	111181061(KCNC3)

PCAD:

102982393(KCNC3)

PSIU:

116743881(KCNC3)

PPHC:

136141531(KCNC3)

NASI:

112415306(KCNC3)

ECB:	111775411(KCNC3)

EPZ:	103545564(KCNC3)

EAI:	106824145(KCNC3)

MYB:	102245578(KCNC3)

MYD:	102773244(KCNC3)

MMYO:

118655405(KCNC3)

MDT:	132216185(KCNC3)

MYUM:

139000392(KCNC3)

PKL:	118718830(KCNC3)

EFUS:

103304786(KCNC3)

MNA:	107531784(KCNC3)

DRO:	112310096(KCNC3)

AJM:	119052008(KCNC3)

PDIC:

114511727(KCNC3)

PHAS:

123830341(KCNC3)

MMF:	118638286(KCNC3)

PPAM:

129082954(KCNC3)

HAI:	109390063 109391004(KCNC3)

RFQ:	117035604(KCNC3)

PALE:

102879377(KCNC3)

PGIG:

120615570(KCNC3)

PVP:	105301781(KCNC3)

RAY:	107500403(KCNC3)

MJV:	108397918(KCNC3)

TOD:	119249613(KCNC3)

SARA:

101545801(KCNC3)

SFUM:

130043628(KCNC3)

SETR:

126027972(KCNC3)

TMU:

101360595

ETF:	101661429(KCNC3)

DNM:	101412877(KCNC3)

SHR:	116423064(KCNC3)

AFZ:

127556857

PCW:	110197741(KCNC3)

TVP:	118839936(KCNC3)

PBRV:

138170851(KCNC3)

MLAO:

141510133(KCNC3)

OAA:	114814594(KCNC3)

TACU:

119933671(KCNC3)

GGA:

CJO:

ACYG:

TGU:

LSR:

PMOA:

OTC:

PRUF:

ATRC:

GFR:

PHI:

ACOE:

ETL:

SVG:

MMEA:

CFAI:

FPG:

FCH:

SHAB:

ACUN:

BBUT:

CSTI:

EGZ:

NNI:	104012499 104012828

PCRI:

PADL:

CBOR:

CBOY:

CNIC:

CUCA:

ASN:	102380772(KCNC3)

AMJ:	102558430(KCNC3)

CIZ:	142024267(KCNC3)

CMY:

102930180

CCAY:

125628391(KCNC3)

NDS:	141976598(KCNC3)

DCC:	119847188(KCNC3)

CPIC:

101950490

CABI:

116817975

MRV:	120388267(KCNC3)

ACS:	100563423(kcnc3)

ASAO:

132777953

PVT:	110074341 110074342 110078490

SUND:

121934253

PBI:

103055424

PMUR:

107282551 107284628 107295530

CTIG:

120304550

TSR:	106549269 106553623

PGUT:

117669133

APRI:

131198463 131205179

PTEX:

113437893 113443601

NSS:	113418616 113432529

VKO:

PMUA:

PRAF:

ZVI:

HCG:	128329628 128335434

GJA:

107116609

STOW:

125444477

EMC:

129340217

XLA:	373613(kcnc1.S) 779437(kcnc3.L)

XTR:

NPR:

RTEM:

ACAT:

PADS:

BBUF:

BGAR:

DTC:

PWL:

MUO:

GSH:

DRE:	559096(kcnc3a) 564371(kcnc3b)

SRX:	107729449 107730758

SANH:

107658413 107667167 107677196 107693499

SGH:	107548332 107555185 107583085 107599741

CCAR:

109059036 109059057 109101681 109113003(kcnc3b)

CAUA:

113042101 113045912 113047187 113071691 113092752

CGIB:

127945928 127949557 127953730 128012999

PTET:

122329748(kcnc3b) 122338148(kcnc3a)

LROH:

127155538(kcnc3b) 127156539(kcnc3a)

GRF:	141300839(kcnc3b) 141335140(kcnc3a)

OMC:	131532988(kcnc3b) 131536904(kcnc3a)

PPRM:

120488181(kcnc3b) 120489576(kcnc3a)

RKG:	130084168(kcnc3b) 130106237(kcnc3a)

MAMB:

125257529(kcnc3b) 125276929(kcnc3a)

CIDE:

127505723 127509213

CERY:

137011847(kcnc3a) 137013804(kcnc3b)

MASI:

127431556 127434426 127449939 127451347

TROS:

130547332(kcnc3b) 130561685(kcnc3a)

TDW:	130413014(kcnc3b) 130425853(kcnc3a)

MANU:

129425412(kcnc3b) 129436075(kcnc3a)

PDAB:

135740404(kcnc3b) 135768350(kcnc3a)

IPU:	108259249(kcnc3a) 108264490(kcnc3b)

IFU:	128602741(kcnc3a) 128605132(kcnc3b)

PHYP:

113528033 113533842

SMEO:

124384268(kcnc3b) 124396667(kcnc3a)

TFD:	113652110(kcnc3b) 113663525(kcnc3a)

TVC:	132845415(kcnc3b) 132861546(kcnc3a)

CGAR:

128520855(kcnc3b) 128544553(kcnc3a)

NGRA:

132868868(kcnc3a) 132886468(kcnc3b)

TRN:	134300177(kcnc3a) 134310920(kcnc3b)

AMEX:

103030038(kcnc3a) 103030489(kcnc3b)

CMAO:

118821438(kcnc3a) 118822273(kcnc3b)

EEE:	113569890 113578456

CHAR:

105891716(kcnc3a) 105910220(kcnc3b)

SPIL:

134070025(kcnc3b) 134076887(kcnc3a)

ASAD:

121699858(kcnc3b) 121704763(kcnc3a)

TRU:	101070192 101072757

TFS:	130514704 130523832(kcnc3b)

TNG:	GSTEN00005544G001

LCO:	104920699 104927163

NCC:

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117246951 117268322

EFO:	125878816 125881260

PLEP:

121957289 121959262

SLUC:

116061219(kcnc3b) 116062824

ECRA:

117936995(kcnc3b) 117958726

ESP:	116671248 116702807

PFLV:

114548448 114570217

GAT:	120819084(kcnc3b) 120827228

PPUG:

119212610 119220255

AFB:	129091426(kcnc3b) 129098676

CLUM:

117735094 117748795(kcnc3b)

PSWI:

130189244 130203269

CANA:

137786247 137789448

CVE:	137888218(kcnc3a)

MSAM:

119916229 119918404

SCHU:

122867812(kcnc3b) 122869301

EARM:

139299852 139303108

CUD:	121503622 121528234

SPUL:

138593189 138602534

LMIX:

132953894 132955595

HTC:	141784963 141810055

ALAT:

119009380(kcnc3b) 119014650

ASTR:

137588882 137609760

PKLU:

139216715 139219655

MZE:	101473996 101485985

ONL:	100703675 100705368

OAU:	116316867 116319907(kcnc3b)

OLA:	101159863 101168545

OML:	112138210 112154621

CSAI:

133419700(kcnc3b) 133421863

XMA:	102227817 102232153

XCO:	114147999 114161784

XHE:	116727663 116736015

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122821260 122823604(kcnc3b)

PPRL:

129363558 129377853

CVG:	107093229 107101225

CTUL:

119775559 119793695

GMU:	124863150 124864025 124874933

NFU:	107388006 107391775

KMR:	108237163(kcnc3b) 108245358

ALIM:

106517428 106529049

NWH:	119421461 119423961

AOCE:

111562453 111584631

EJA:	138202044 138214248

BFRE:

138616948 138634831

MCEP:

124998371

CSEM:

103382001 103393546

POV:	109627117 109639951

SSEN:

122758922 122785236

SSOE:

131448649 131474919

HHIP:

117753330 117766876

HSP:	118100359 118123921

PPLT:

128427062 128458690

SMAU:

118287472(kcnc3b) 118288991

LCF:	108884423 108898540

SDU:	111220012 111236262

SLAL:

111658665 111667229

XGL:	120788350 120794447

HCQ:	109508608 109523968

SSCV:

125983241 125990912

SBIA:

133495598(kcnc3b) 133515147

PEE:	133414781 133418051(kcnc3b)

PTAO:

133466159 133469279(kcnc3b)

BPEC:

110158162 110159717

ENY:	140357811 140368959

MALB:

109963610 109973698

BSPL:

114859820

SJO:	128378535 128381135

SSCO:

133998902 134003222

TTY:	137172635(kcnc3b) 137201435

GMH:	115531675 115534370

SASA:

106578302 106579175 106583948 106600760

STRU:

115160310 115170830 115192159 115200960

OTW:	112223743 112224085 112251230 112259162

OMY:	110491650 110498792 110521873 110537936(kcnc3a)

OGO:	124037969 124039002 124048395

ONE:	115106614 115110048 115143930 115145271

OKI:	109865874 109869940 109893141 109897546

OKE:	118358914 118365005(kcnc3b) 118384125

OMM:	135504869 135555953 135556123

OCLA:

139368189 139377470 139406844 139420929

SALP:

111971439 111976483 111978281 111980800

SNH:	120044430 120045510(kcnc3b) 120051928 120060854

SFON:

129823442(kcnc3a) 129855502 129855672 129860376

CCLU:

121547188 121550361 121566959 121569776

ELS:	105030699 105031448

OEP:	134009059 134031272

SFM:	108923929 108941626

PKI:	111836930 111858243

AANG:

118217400(kcnc3a) 118219755

AROT:

135243060(kcnc3a) 135248016

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

120541857(kcnc3a)

LCM:

RTP:

CPLA:

CPUN:

HOC:

SCAU:

STOZ:

LERI:

HAKA:

APLC:

GAE:

HRF:

HASI:

CRG:

CANU:

128167862 128188029 128190061

OED:

MYI:

RPHI:

MAEA:

LJP:

PDAM:

SPIS:

111336335 111336764 111336767

HSY:

130641065

MPP:	MICPUCDRAFT_59734

» show all

Reference

PMID:16501573

Authors

Waters MF, Minassian NA, Stevanin G, Figueroa KP, Bannister JP, Nolte D, Mock AF, Evidente VG, Fee DB, Muller U, Durr A, Brice A, Papazian DM, Pulst SM

Title

Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes.

Journal

Nat Genet 38:447-51 (2006)
DOI:10.1038/ng1758

Sequence

[hsa:3748]

Reference

PMID:10712820

Authors

Rae JL, Shepard AR

Title

Kv3.3 potassium channels in lens epithelium and corneal endothelium.

Journal

Exp Eye Res 70:339-48 (2000)
DOI:10.1006/exer.1999.0796

Sequence

[hsa:3748]

LinkDB

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