Homo sapiens (human): 9312
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Entry
9312 CDS
T01001
Symbol
KCNB2, KV2.2
Name
(RefSeq) potassium voltage-gated channel subfamily B member 2
KO
K04886
potassium voltage-gated channel Shab-related subfamily B member 2
Organism
hsa
Homo sapiens (human)
Drug target
Amifampridine:
D10228
D10689
<JP/US>
Fampridine:
D04127
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
9312 (KCNB2)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Potassium channel, voltage-gated (Kv)
9312 (KCNB2)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kv2channel
Ion_trans
BTB_2
Ion_trans_2
DUF5843
DUF4790
Motif
Other DBs
NCBI-GeneID:
9312
NCBI-ProteinID:
NP_004761
OMIM:
607738
HGNC:
6232
Ensembl:
ENSG00000182674
UniProt:
Q92953
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All DBs
Position
8:72537225..72938349
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AA seq
911 aa
AA seq
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MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTR
LGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFG
QELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLW
DLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVC
IAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVV
QIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDE
DATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNF
SEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESANTKD
SADDNHLSPSRWKWARKALSETSSNKSFENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKL
EMLYNEITKTQPHSHPNPDCQEKPERPSAYEEEIEMEEVVCPQEQLAVAQTEVIVDMKST
SSIDSFTSCATDFTETERSPLPPPSASHLQMKFPTDLPGTEEHQRARGPPFLTLSREKGP
AARDGTLEYAPVDITVNLDASGSQCGLHSPLQSDNATDSPKSSLKGSNPLKSRSLKVNFK
ENRGSAPQTPPSTARPLPVTTADFSLTTPQHISTILLEETPSQGDRPLLGTEVSAPCQGP
SKGLSPRFPKQKLFPFSSRERRSFTEIDTGDDEDFLELPGAREEKQVDSSPNCFADKPSD
GRDPLREEGSVGSSSPQDTGHNCRQDIYHAVSEVKKDSSQEGCKMENHLFAPEIHSNPGD
TGYCPTRETSM
NT seq
2736 nt
NT seq
+upstream
nt +downstream
nt
atggcagaaaaggctcccccgggcttaaacaggaagacttcaaggtcgacactttccctt
cctccagagcctgtggacattatccggagcaaaacatgctccaggagagttaagatcaat
gtggggggcctcaaccacgaagtcctgtggagaacgctggacaggctgcccaggacgcgc
ctggggaagcttcgagactgcaacacacacgagagcctcctggaagtgtgcgacgactat
aatctgaacgagaacgagtatttctttgatcggcatccaggagccttcacttccatttta
aatttctaccggaccgggaaactccatatgatggaagaaatgtgtgcactttcgtttggc
caagaacttgattactgggggattgatgagatctacttggagtcctgctgccaggccaga
tatcatcaaaaaaaagaacaaatgaacgaagaactgaggcgagaggcagagactatgcga
gagcgagaaggagaagagtttgataatacctgctgccctgataaaaggaagaaactgtgg
gacttgctggagaaacctaactcatcagtggctgcaaagatcctggccatcgtgtctatc
ctgttcattgtgctttccaccattgctttgtctctcaatacgctgccggagctgcaggaa
acggacgaatttggacaactcaatgacaaccgccaattagcacacgtggaggctgtgtgt
attgcatggtttaccatggagtaccttttgcgattcttatcctcaccaaataaatggaag
ttcttcaaaggcccactgaatgtcattgatttgctggccatcttgccgtactatgtcacc
atttttctgacggagtccaacaagagcgtgctgcagttccaaaacgtgaggcgcgtggtc
cagatcttccgaatcatgcgcatcctcaggatcctgaaactcgccaggcattcgacaggc
ctgcagtctctgggtttcacccttaggcggagttacaatgaattgggcttgttgatattg
tttctggccatggggataatgatattttccagcctggtattttttgctgagaaggatgaa
gatgctaccaagttcaccagtatccctgcatcattttggtgggccaccatcaccatgacc
actgttggctatggtgacatttaccctaaaacattactagggaaaattgtgggaggtctg
tgctgtattgctggggttctggttattgcccttcctatcccaattattgtgaacaatttt
tctgagttttacaaggagcagaaacgccaagagaaagcaattaaaaggagggaggctctt
gagcgggccaaaaggaacggaagcatcgtttctatgaacttaaaagatgccttcgctcga
agtatggaactgatagatgtggctgttgagaaggccggagagtccgccaacacaaaggac
tccgccgacgataatcacctgtcgccaagccggtggaagtgggccaggaaggctctgtcg
gaaacaagctccaacaagtctttcgagaataagtaccaggaggttagccaaaaagactcc
cacgagcagctgaacaacacgtcttcctccagcccacagcatctgagtgcccagaaactg
gagatgctatacaatgaaatcaccaagacacagcctcattctcacccaaacccagactgc
caagaaaagcctgagaggccatctgcatatgaagaagagattgaaatggaagaagtggtg
tgtccacaggagcagctggccgtggcacagaccgaggtcattgtggacatgaagagcacc
tccagcatcgacagcttcaccagctgtgccaccgacttcacagagacagagagatcgccg
ctgccgccgccctccgcctctcacttgcagatgaagttcccaaccgacctcccagggaca
gaagagcaccaaagagctaggggccccccgtttctaactctatccagagagaaaggacct
gctgccagggatggcacgctggagtatgccccagttgacataactgtgaacctcgatgcc
agtggctcccagtgtgggctacatagtcctttgcagtctgacaatgccaccgacagtcct
aagagctctctaaaaggcagcaacccactaaagtccagatccctcaaagtgaactttaag
gaaaatagaggcagtgcaccacagaccccgcccagcacagccaggccactgccagtcacc
acagctgacttttcgctcactaccccgcagcacatcagtaccatcctcttagaagaaacc
ccctcccagggagacagacccttgctgggcactgaggtttcagcgccttgtcagggacct
tccaaagggctgtcccccaggtttcccaagcagaaactgttccctttctcttcaagagag
aggaggagcttcactgaaatagatactggtgacgacgaagacttcttagagctcccaggg
gcaagggaggagaagcaggtggactccagcccaaattgctttgcagataagcctagtgat
gggagagaccctttaagagaagagggcagtgtgggctcttcctccccgcaggacacaggt
cacaactgtaggcaagacatttaccatgctgtgagtgaagtcaaaaaggacagtagtcaa
gaagggtgcaagatggaaaatcacttgtttgccccagaaattcattccaacccaggagac
acaggttattgtcccacacgtgaaaccagcatgtga
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