KEGG   DRUG: Somapacitan
Entry
D11194                      Drug                                   

Name
Somapacitan (USAN/INN);
Somapacitan (genetical recombination) (JAN);
Somapacitan-beco;
Sogroya (TN)
Formula
C1038H1609N273O319S9
Exact mass
23290.5561
Mol weight
23305.1048
Sequence
FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT
PSNREETQQK SNLELLRISL LLIQSWLEPV QFLRSVFANS CVYGASDSNV YDLLKDLEEG
IQTLMGRLED GSPRTGQIFK QTYSKFDTNS HNDDALLKNY GLLYCFRKDM DKVETFLRIV
QCRSVEGSCG F
(Disulfide bridge: 53-165, 182-189)
  Type
Peptide
Remark
Therapeutic category: 2412
ATC code: H01AC07
Product: D11194<JP>
Efficacy
Growth hormone (GH) receptor agonist
  Disease
Growth hormone deficiency [DS:H00254]
Comment
Treatment of growth hormone dificiency
albumin-binding growth hormone
Target
GHR [HSA:2690] [KO:K05080]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04080  Neuroactive ligand-receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
   H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
    H01AC Somatropin and somatropin agonists
     H01AC07 Somapacitan
      D11194  Somapacitan (USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   241  Pituitary hormone preparations
    2412  Anterior pituitary hormones
     D11194  Somapacitan (USAN/INN); Somapacitan (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    GHR
     D11194  Somapacitan (USAN/INN) <JP>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11194
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11194
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D11194
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11194
Other DBs
CAS: 1338578-34-9
PubChem: 384585173
LinkDB

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