KEGG   DRUG: Solriamfetol
Entry
D11315                      Drug                                   
Name
Solriamfetol (USAN)
Formula
C10H14N2O2
Exact mass
194.1055
Mol weight
194.23
Structure
Simcomp
Class
Neuropsychiatric agent
 DG03059  Noradrenalin and dopamine reuptake inhibitor (NDRI)
Remark
ATC code: N06BA14
Chemical structure group: DG02989
Product (DG02989): D11328<US>
Efficacy
Wake-promoting agent, Noradrenalin and dopamine reuptake inhibitor
Comment
Wake-promoting agent for the treatment of excessive sleepiness associated with narcolepsy or obstructive sleep apnea
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
  Pathway
hsa04721  Synaptic vesicle cycle
hsa04728  Dopaminergic synapse
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA14 Solriamfetol
      D11315  Solriamfetol (USAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03059  Noradrenalin and dopamine reuptake inhibitor (NDRI)
   DG02989  Sorliamfetol
    D11315  Solriamfetol
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D11315  Solriamfetol (USAN)
    SLC6A3 (DAT1)
     D11315  Solriamfetol (USAN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG03059  Noradrenalin and dopamine reuptake inhibitor (NDRI)
   DG02989  Sorliamfetol
Other DBs
CAS: 178429-62-4
PubChem: 384585293
LinkDB
KCF data

ATOM        14
            1   C8x C     4.9000  -17.5700
            2   C8x C     4.9000  -18.9700
            3   C8x C     6.1124  -19.6700
            4   C8x C     7.3249  -18.9700
            5   C8y C     7.3249  -17.5700
            6   C8x C     6.1124  -16.8700
            7   C1b C     8.5560  -16.8590
            8   C1c C     9.7612  -17.5547
            9   C1b C    10.9435  -16.8719
            10  O7a O    12.1375  -17.5612
            11  C7a C    13.3254  -16.8752
            12  N1a N    14.5165  -17.5629
            13  O6a O    13.3255  -15.4702
            14  N1a N     9.7616  -18.9696
BOND        14
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   11  13 2
            14    8  14 1 #Down

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