| Entry |
|
|---|
| Name |
Trastuzumab deruxtecan (USAN/INN);
Trastuzumab deruxtecan (genetical recombination) (JAN);
Fam-trastuzumab deruxtecan-nxki;
Enhertu (TN)
|
|---|
| Product |
|
|---|
| Formula |
C6460H9972N1724O2014S44. (C52H57FN9O13)8
|
|---|
| Exact mass |
153607.1079
|
|---|
| Mol weight |
153701.9811
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic |
|---|
| Disease |
Breast cancer (HER2 positive) [DS: H00031] |
|---|
| Comment |
Antibody-drug conjugate
|
|---|
| Target |
|
|---|
| Pathway |
| hsa01521 | EGFR tyrosine kinase inhibitor resistance |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
EGFR family
ERBB2 (HER2, CD340)
D11529 Trastuzumab deruxtecan (USAN/INN) <US>
Enzymes
Isomerases (EC5)
DNA topoisomerase
TOP1
D11529 Trastuzumab deruxtecan (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D11529
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D11529
 |
|---|
| Other DBs |
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|---|
| LinkDB |
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|---|
