DRUG: Mecbotamab vedotin
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Entry
D12220 Drug
Name
Mecbotamab vedotin
Efficacy
Antineoplastic
Type
Antibody-drug conjugate
Comment
Treatment of cancers expressing the AXL transmembrane receptor protein
Target
AXL [HSA:
558
] [KO:
K05115
]
TUBB [HSA:
10381
10382
10383
203068
347688
347733
7280
81027
84617
] [KO:
K07375
]
Pathway
hsa01521
EGFR tyrosine kinase inhibitor resistance
Brite
Target-based classification of drugs [BR:
br08310
]
Protein kinases
Receptor tyrosine kinases (RTK)
AXL family
AXL
D12220 Mecbotamab vedotin
Not elsewhere classified
Cellular process
Cytoskeleton
TUBB
D12220 Mecbotamab vedotin
BRITE hierarchy
Other DBs
CAS:
2460400-64-8
PubChem:
497620633
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