| Entry |
|
|---|
| Name |
Tasurgratinib (INN) |
|---|
| Formula |
C32H37N5O6
|
|---|
| Exact mass |
587.2744
|
|---|
| Mol weight |
587.67
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03234 Tasurgratinib
D12404 Tasurgratinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
FGFR family
FGFR1 (CD331)
D12404 Tasurgratinib (INN)
FGFR2 (CD332)
D12404 Tasurgratinib (INN)
FGFR3 (CD333)
D12404 Tasurgratinib (INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03234 Tasurgratinib
|
|---|
| Other DBs |
|
|---|
| LinkDB |
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|---|
| KCF data |
ATOM 43
1 N1y N 11.1769 -18.4355
2 C1x C 11.1769 -16.9690
3 C1x C 12.4339 -16.2707
4 C1y C 13.6210 -16.9690
5 C1x C 13.6210 -18.4355
6 C1x C 12.4339 -19.1338
7 C1b C 9.9898 -19.1338
8 C1b C 8.8026 -18.4355
9 C8y C 14.8081 -16.2707
10 C8x C 14.8081 -14.8741
11 C8x C 16.0651 -14.1758
12 C8y C 17.2522 -14.8741
13 C8x C 17.2522 -16.2707
14 C8x C 16.0651 -16.9690
15 C5a C 18.5092 -14.1758
16 O1a O 7.5875 -19.1239
17 O5a O 18.5263 -12.7792
18 N1b N 19.7085 -14.8914
19 C8y C 19.7085 -16.2881
20 N5x N 18.4975 -16.9873
21 C8x C 18.4975 -18.3839
22 C8x C 19.7071 -19.0822
23 C8y C 20.9181 -18.3830
24 C8x C 20.9181 -16.9864
25 O2a O 22.0941 -19.0620
26 C8y C 23.2850 -18.3742
27 C8x C 24.4703 -19.0586
28 C8y C 25.6799 -18.3602
29 C8y C 25.6799 -16.9636
30 C8x C 24.4945 -16.2794
31 C8y C 23.2850 -16.9776
32 O2a O 22.0513 -16.2652
33 C1b C 22.0513 -14.8686
34 C1b C 23.2728 -14.1633
35 C8x C 27.0080 -18.7919
36 C8x C 27.8291 -17.6619
37 N4y N 27.0081 -16.5321
38 C5a C 27.4365 -15.2142
39 N1b N 28.8114 -14.9222
40 O5a O 26.5115 -14.1867
41 C1a C 29.7711 -15.9887
42 O2a O 23.2732 -12.7404
43 C1a C 24.4609 -12.0548
BOND 47
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 4 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 13 14 2
15 9 14 1
16 12 15 1
17 8 16 1
18 15 17 2
19 15 18 1
20 18 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 19 24 1
27 23 25 1
28 25 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 29 30 1
33 30 31 2
34 26 31 1
35 31 32 1
36 32 33 1
37 33 34 1
38 28 35 1
39 35 36 2
40 36 37 1
41 29 37 1
42 37 38 1
43 38 39 1
44 38 40 2
45 39 41 1
46 34 42 1
47 42 43 1
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