| Entry |
|
|---|
| Name |
Zanzalintinib (USAN/INN) |
|---|
| Formula |
C29H25FN4O5
|
|---|
| Exact mass |
528.1809
|
|---|
| Mol weight |
528.53
|
|---|
| Structure |
|
|---|
| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Receptor tyrosine kinase inhibitor |
|---|
| Comment |
Treatment of solid tumors
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03273 Zanzalintinib
D12650 Zanzalintinib
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
VEGFR family
VEGFR2 (KDR)
D12650 Zanzalintinib (USAN/INN)
MET family
MET
D12650 Zanzalintinib (USAN/INN)
AXL family
AXL
D12650 Zanzalintinib (USAN/INN)
TYRO3
D12650 Zanzalintinib (USAN/INN)
MERTK
D12650 Zanzalintinib (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03273 Zanzalintinib
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 39
1 C8y C 24.5096 -27.2001
2 C8x C 24.5096 -28.6044
3 C8x C 23.3160 -29.3065
4 C8y C 22.0522 -28.6044
5 C8x C 22.0522 -27.2001
6 C8x C 23.3160 -26.4980
7 X F 25.7032 -26.4980
8 N1b N 20.8586 -29.3065
9 C5a C 19.6650 -28.6044
10 C1z C 18.4714 -29.3065
11 C5a C 17.2777 -28.6044
12 N1b N 16.0841 -29.3065
13 O5a O 17.2777 -27.2001
14 O5a O 19.6650 -27.2001
15 C8y C 14.8905 -28.6044
16 C8x C 13.6969 -29.3065
17 C8x C 12.4331 -28.6044
18 C8y C 12.4331 -27.2001
19 C8x C 13.6267 -26.4980
20 C8x C 14.8905 -27.2001
21 O2a O 11.2395 -26.4980
22 C1x C 19.1735 -30.5001
23 C1x C 17.7692 -30.5001
24 C8y C 11.2395 -25.0980
25 C8y C 12.4602 -24.3929
26 C8y C 12.4599 -22.9929
27 N5x N 11.2473 -22.2931
28 C8x C 10.0266 -22.9983
29 C8x C 10.0269 -24.3983
30 C8x C 13.6728 -25.0926
31 C8y C 14.8851 -24.3923
32 C8y C 14.8848 -22.9923
33 C8x C 13.6722 -22.2926
34 O2a O 16.1301 -22.2735
35 C1a C 17.3140 -22.9572
36 C5a C 16.1018 -25.0946
37 N1b N 17.3277 -24.3871
38 O5a O 16.1017 -26.4600
39 C1a C 18.5518 -25.0945
BOND 43
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 4 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 11 13 2
14 9 14 2
15 12 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 18 19 1
20 19 20 2
21 15 20 1
22 18 21 1
23 22 23 1
24 23 10 1
25 10 22 1
26 21 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 27 28 1
31 28 29 2
32 24 29 1
33 25 30 1
34 30 31 2
35 31 32 1
36 32 33 2
37 26 33 1
38 32 34 1
39 34 35 1
40 31 36 1
41 36 37 1
42 36 38 2
43 37 39 1
|
|---|
