KEGG   ORTHOLOGY: K00066
Entry
K00066                      KO                                     
Symbol
algD
Name
GDP-mannose 6-dehydrogenase [EC:1.1.1.132]
Pathway
map00051  Fructose and mannose metabolism
map00520  Amino sugar and nucleotide sugar metabolism
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
map02020  Two-component system
Reaction
R00880  GDP-D-mannose:NAD+ 6-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K00066  algD; GDP-mannose 6-dehydrogenase
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    K00066  algD; GDP-mannose 6-dehydrogenase
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K00066  algD; GDP-mannose 6-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.132  GDP-mannose 6-dehydrogenase
     K00066  algD; GDP-mannose 6-dehydrogenase
Other DBs
GO: 0047919
Genes
LARE: HIV01_005960
PRE: PCA10_11880(algD) PCA10_38230(algD)
PFUW: KF707C_11170
POJ: PtoMrB4_26000(algD) PtoMrB4_46190
PLAL: FXN65_05555
PAE: PA3540(algD)
PAEV: N297_3663(algD)
PAEI: N296_3663(algD)
PAU: PA14_18580(algD)
PAG: PLES_14931(algD)
PAF: PAM18_1446(algD)
PNC: NCGM2_4665(algD)
PAEB: NCGM1900_2744(algD)
PDK: PADK2_06665
PSG: G655_07100
PRP: M062_18755
PAEP: PA1S_07720
PAER: PA1R_gp1358
PAEM: U769_07195
PAEL: T223_07435
PAES: SCV20265_1523
PAEU: BN889_03910(algD)
PAEG: AI22_26185
PAEC: M802_3660(algD)
PAEO: M801_3528(algD)
SECH: B18_00665
PCQ: PcP3B5_50680(algD)
PMUI: G4G71_08975
PNT: G5B91_26160
PAP: PSPA7_1605(algD)
PPAA: B7D75_07435
PPU: PP_1288(algD)
PPF: Pput_4437
PPG: PputGB1_4561
PPW: PputW619_0889
PPT: PPS_4403
PPB: PPUBIRD1_4273
PPI: YSA_03091
PPX: T1E_3168(algD)
PPUH: B479_22150
PPUT: L483_27235
PPUN: PP4_08000(algD)
PPUD: DW66_4794
PFV: Psefu_3880
PMON: X969_21685
PMOT: X970_21320
PPJ: RK21_00119
PMOL: CLJ08_08380 CLJ08_22925
PALD: LU682_024945
PIX: RIN61_07120
PWD: LOY45_11485 LOY45_22080
PSSG: CWR53_04400
PMOS: O165_013045 O165_018560
PST: PSPTO_1243(algD)
PSB: Psyr_1063
PSYR: N018_20355
PSP: PSPPH_1118(algD)
PSAV: PSA3335_09095
PAMG: BKM19_008085
PCI: PCH70_10130
PAVL: BKM03_07020
PVD: CFBP1590__4277(algD)
PCAB: JGS08_19525
PCOF: POR16_18925
PTRE: I9H09_05090
PSYI: MME58_05275
PAST: N015_05985
PLIJ: KQP88_04855
PFUV: NLK61_18730
PFL: PFL_1024(algD)
PPRC: PFLCHA0_c10440(algD)
PPRO: PPC_1062
PFE: PSF113_4752
PZA: HU749_024140
PFN: HZ99_11915
PFO: Pfl01_0960(algD)
PFS: PFLU_0990(algD)
PFC: PflA506_0970(algD)
PPZ: H045_01690
PFB: VO64_4071
PMAN: OU5_2447
PTV: AA957_09045
PCG: AXG94_09975
PVR: PverR02_05230
PAZO: AYR47_12230
POI: BOP93_04735
PRX: HRH33_05805
PMED: E3Z27_23120
PKR: AYO71_07540
PMUD: NCTC8068_04321(algD)
PTOL: I7845_05045
PMAB: U0037_04980
PBRE: QDY63_24165
PEXT: LUU92_05180
PFW: PF1751_v1c09480(algD)
PFF: PFLUOLIPICF703390
PFX: A7318_04290
PEN: PSEEN3453(algD-2) PSEEN4535(algD)
PBA: PSEBR_a4590
PBC: CD58_24305
PPUU: PputUW4_04471(algD)
PDR: H681_19425
PSV: PVLB_04235 PVLB_15470
PSK: U771_06125
PKC: PKB_0968(algD)
PCH: EY04_04520
PCZ: PCL1606_50710
PCP: JM49_25125
PCHP: C4K32_1103
PFZ: AV641_18510
PLQ: AA042_15150
PALK: PSAKL28_08740 PSAKL28_31810
PPV: NJ69_13830
PSES: PSCI_0721
PSEM: TO66_05210
PSEC: CCOS191_0912(algD1) CCOS191_2029(algD2)
PPSY: AOC04_15730
PSOS: POS17_1030
PFK: PFAS1_06330
PANR: A7J50_0992
PSET: THL1_1268 THL1_3804
PSIL: PMA3_24585
PYM: AK972_0838
PKE: DLD99_05160
PUM: HGP31_04975
PGG: FX982_00687
PGY: AWU82_19080 AWU82_29005
PSEJ: HNQ25_10170 HNQ25_19280
PVK: EPZ47_24330
PEZ: HWQ56_05050
PBZ: GN234_24015
PATA: JWU58_22750
PDW: BV82_3321 BV82_4690
PZE: HU754_006270
PMOE: HV782_005850
PSEP: C4K39_1041
PPII: QL104_05175
PDAN: PFZ56_10950
PVW: HU752_027430
PTRT: HU722_0006165
PXA: KSS93_07790
PSAM: HU731_021005
PTZ: HU718_005910
PQI: KH389_10480 KH389_22245
PSHH: HU773_022835
PXN: HU772_004420 HU772_009430
PHV: HU739_012710
PPRG: HU725_004085 HU725_014400
PANH: HU763_020330
PASG: KSS96_05695
PFAK: KSS94_04615
PMUY: KSS95_07475 KSS95_11760
PMAM: KSS90_04835 KSS90_09905
PAZE: KSS91_23845
PALV: KSS97_06295
PCAS: LOY40_05230
PORY: EJA05_04800
PWZ: J7655_04690(algD)
PTK: EXN22_12380 EXN22_22955
PTW: TUM18999_50120(algD)
PIE: HU724_005670
PWY: HU734_005480
PGF: J0G10_06075
PCAV: D3880_05550 D3880_05610
PJU: L1P09_20850
PIZ: LAB08_R50410
PPEG: KUA23_05150
PSII: NF676_05345
PSIH: LOY51_04705
PFIT: KJY40_05935
PASI: LG197_00315
PKM: PZ739_23450
PNB: NK667_22335
PSOA: PSm6_09920(algD)
PTAI: ICN73_10950
PKK: QQ992_23595
PKJ: Q1W70_05470 Q1W70_21865
PHYG: JTY93_21615
PHOM: KJF94_01550 KJF94_13595
PCUC: PSH97_04640
PTRL: OU419_22545(algD)
PPAE: LDL65_16250
PPAO: K3169_23650
PRHZ: CRX69_09220
PSJY: AA098_05025
PSKU: KUIN1_11040
PSHS: JJN09_02540
PHEF: PSH57_05225
PSLP: BHQ29_07820 BHQ29_17130
PLIS: NN484_01390
PSNC: C0058_26885
PFOU: OZ911_23940
PBEJ: PSH84_01850
PKV: QYQ93_05900
PSKP: KU43P_18940 KU43P_44560
PDEU: QEP73_14595
PQE: OSC50_19425
PSDT: NH234_05830
PCAA: V6L78_29655
PSIV: LZ023_33740
PSWO: SD196_21735(algD)
PMOR: PMm318_A01820
PTHV: CE140_22400
PSSX: DCC84_28260
PAGB: AWM79_03600
PSNS: CI807_11825
PSRU: CCX46_04885
PSNY: ACPFMA_05065
PSMD: K5R88_07535 K5R88_25895
PIM: OQ460_20600
PBAB: AAEO81_05605
PSYQ: HXW90_05545
PTUS: QC631_003745(algD) QC631_008855
PSLZ: B195_018025
PSSZ: DJ564_06000
PSDY: D6Z43_05910 D6Z43_13885
PSDU: C2E19_06315
PABN: ABDX87_09240
PSHN: LVW35_04895
PSND: NY023_23095
PVII: AABC73_05625
PSDD: N0B28_09975 N0B28_21635
PVQ: WOB24_01670
PSTP: ACOAPY_11905
PSHL: CS390_10215
PBER: HS968_06000
PSMP: ELQ88_29185
PSSJ: FXO12_12670
PDAL: PALTO1_09720(algD)
PMY: Pmen_1031 Pmen_1678
PMK: MDS_1082
PALL: UYA_04885 UYA_15320
PKH: JLK41_05220(algD)
PTY: JWV26_01370 JWV26_15965(algD)
PHF: NLY38_05240(algD) NLY38_16715
PCHE: QYM18_12805(algD) QYM18_23005(algD)
ECOP: L0Y47_05480(algD)
AVN: Avin_10970(algD)
AVL: AvCA_10970(algD)
AVD: AvCA6_10970(algD)
ACX: Achr_31180(algD)
EAZ: JHT90_07865
ENTO: MTZ49_11930
PDEN: F1C79_17950
PPHA: BVH74_05210
PALC: A0T30_11805
PCAM: HNE05_07125
MSR: AU15_13665
MACA: J2887_18610
GAG: Glaag_2800
PMES: FX988_01104
PAT: Patl_1531
HMI: soil367_08790
ALKM: NKI27_00790
CEG: D0C16_11005
GIL: NHM04_15470
MNY: R50073_15990
HAUI: ABXT62_16600
MEIY: MIN45_P0136
THIM: KFB96_07615
TFRI: Thiofri_03630(algD)
ABO: ABO_0384(algD)
ALN: AS19_03970
GSN: YC6258_00963
OME: OLMES_2098 OLMES_4477
TAU: Tola_1407
SVA: SVA_1550
REV: HUE57_13005
PLG: NCTC10937_04283(algD)
RFR: Rfer_0673
PAQA: K9V56_012855 K9V56_012880
PAIS: PFX98_20965
ATER: MW290_14625
JAG: GJA_3986(algD)
JAL: BZG29_08185
JAS: FJQ89_25120
JLV: G3257_08340
JRI: P9875_08610
JAE: OPV09_08525
MNR: ACZ75_11680
MASY: DPH57_12210
MENY: LSQ66_04000
MASZ: C9I28_09765
MFLA: GO485_23875
MPLI: E1742_23455
TCT: PX653_13240
PLUE: EWM63_05620
EHB: E7V67_006890
NDM: RBH92_05285
MUV: FIT94_04050
EBA: ebA4268(algD)
AZO: azo3269(algD)
AOA: dqs_3408
THAJ: AAG895_05040
ACOM: CEW83_18780
APP: CAP2UW1_0858 CAP2UW1_1431
ACOG: HWD57_11430
AMAX: ABWH92_04635
ARUI: G6M88_17210
RHL: LPU83_pLPU83d0171(algD1) LPU83_pLPU83d1236(algD3)
RGR: FZ934_26065
RROS: D4A92_02485 D4A92_22670
RSUL: N2599_29805
RHIU: IM739_19050
BJA: blr6296(blr6296)
BRA: BRADO7047
BRS: S23_62720
BRC: BCCGELA001_11045
BIC: LMTR13_08410
BRK: CWS35_18850
BRQ: CIT40_06180
BSYM: CIT39_05020
BARH: WN72_18950
BEL: BE61_69060
BSEP: HAP48_0031560
BQB: J4P68_0032835
BAUT: QA635_27835
BBRA: QA636_29730
BPAH: QA639_16165
BRAB: RX331_09160
BRAH: RX329_27910
TARV: FIU28_16890
MNO: Mnod_5882
METI: DK427_06650
MTEZ: HPT29_006150
BID: Bind_3885
MPAR: F7D14_18240
MAAD: AZF01_02675
MMED: Mame_02304(algD)
MLUT: JET14_03725
JAV: OXU80_00280
RBM: TEF_19885
LABR: CHH27_22980
LABP: FJ695_16660
RPOP: K1718_15110
ACUT: MRB58_00060
RUY: NOR97_20535
DSH: Dshi_1896(algD)
MALG: MALG_02776
CON: TQ29_00725
YPAC: CEW88_18640
YAN: AYJ57_24995
SULZ: C1J03_23160
TOM: BWR18_20775
THAA: CFI11_06320 CFI11_06490
RMH: LVO79_06000
HAT: RC74_06375
LSAL: KBK07_17255
TRY: QF118_01765
THW: BMG03_12925
TLB: RPE78_12915
YPHY: AABB29_07900
YRH: AABB31_14955
LIT: FPZ52_00565
PPRU: FDP22_22880
POZ: I0K15_05930
CACT: HZ995_12210
HDH: G5B40_09200
AMYL: QBD29_07855
FAQ: G5B39_18330
NAR: Saro_3220
NAEO: ACLIMP_18845
SPHI: TS85_22025
SSAN: NX02_04640
ACOB: P0Y56_12580
EGN: BMF35_a0516
ERF: FIU90_00265(algD)
ERYT: KDC96_15245
PHZ: CHX26_00290
POT: E2E27_01460
PORU: KVF90_00385
RAP: RHOA_PB0089(algD)
HTQ: FRZ44_03090(algD)
HADH: FRZ61_03380(algD)
MVP: P4R82_19690
SNEA: NBZ79_19285
MINW: ACMVY4_02945
NIS: NIS_0191
CMED: FE773_08555
CPAF: C6V80_01890
DVE: DESUT3_23450(algD)
DSA: Desal_3469
DTO: TOL2_C36540(algD)
BMX: BMS_2990
STI: Sthe_1134
SLOM: PXH66_05790
OLV: ACMYLB_10770
ROO: G5S37_25645
FPES: NXS98_06570
AHEL: Q31a_57060(algD)
SMAM: Mal15_36880(algD)
MRI: Mal4_03640(algD)
SDYN: Mal52_06430(algD)
SCHL: QJS52_01950
SSPE: ACGY09_01855
LALU: SH248x_001646
FTJ: FTUN_5650
ABA: Acid345_3792
TRS: Terro_2830
ADIN: H7849_05985
OBV: P8935_13600
SUS: Acid_0553
LUB: TBR22_A24300(algD)
BDO: EL88_09425
NKO: Niako_7100
CMR: Cycma_0720
EMAI: KZP23_20245
SPIB: G8759_29085
SRHO: HH216_01470
SENF: GJR95_15585
SPIO: WBJ53_24135
DSN: HWI92_00320
DEND: ACN9ML_00320
FIB: A6C57_20705
PKO: PKOR_16530
CLIT: OQ292_40240
PRHO: PZB74_20200
TPEL: P0M28_17740
CNQ: PZB72_28250
ZGA: ZOBELLIA_1984(algD)
MLIL: QLS71_002625
PPON: MUN68_016515
CACI: CLOAM0663
TAM: Theam_0797
NMV: NITMOv2_2630(algD)
NNEO: PQG83_09560
PARH: I5S86_05480
PHEX: L0M14_20510
LBP: V1224_13340
HSG: HPPSJP_3770(rkpK)
MSM: MSMEG_5957(algD)
MSG: MSMEI_5797
MSB: LJ00_29460
MSN: LI99_29465
MSH: LI98_29470
MVA: Mvan_1699
MAUS: JN090_07325
MSP: Mspyr1_41390
MNE: D174_24385
MYN: MyAD_23925
MTY: MTOK_31270(algD)
MSAR: MSAR_24600(algD)
MANY: MANY_49000(algD)
MPOF: MPOR_19690
MGO: AFA91_10990 AFA91_29875
MRF: MJO55_24360
MDF: K0O62_25565
MFRE: EXE63_09795
MFLU: HZU40_32750
NHU: H0264_19875
ROP: ROP_57960(algD)
RKO: JWS14_31405
RHOY: QNA09_05105
TOY: FO059_04060
SCO: SCO0382(SCF62.08)
SGRF: SGFS_035730
SCB: SCAB_23351
SVL: Strvi_5599
SHY: SHJG_7006
SHO: SHJGH_6766
SRC: M271_40840
SBH: SBI_09543
SVE: SVEN_7199
SLV: SLIV_36030(algD)
SVT: SVTN_36100
STRE: GZL_08291
SLD: T261_7968
SPRI: SPRI_2000
STRF: ASR50_26930
SPAV: Spa2297_31800
STRT: A8713_24610
SCLF: BB341_00345
SGS: AVL59_31095
SALW: CP975_03365
SGM: GCM10017557_19510
SGRS: V9K83_07275
SLS: SLINC_8140
SNR: SNOUR_37270(algD)
SALU: DC74_1121
SALL: SAZ_06100
SPLU: LK06_025850
STRD: NI25_00640
SSIA: A7J05_09315
SGV: B1H19_04475
SALF: SMD44_08071(algD)
STRO: STRMOE7_01550
SFK: KY5_0166c
SGE: DWG14_01282(algD_2)
SLK: SLUN_34570
SQZ: FQU76_01535
SCYA: EJ357_37150
SKA: CP970_42095
SVR: CP971_03305
SFY: GFH48_34990
SBY: H7H31_29485
SFUG: CNQ36_29650
STSU: B7R87_32065
SCHA: CP983_11050
SGX: H4W23_37670
SCOE: CP976_05755
SSPB: CP982_01460
SHUN: DWB77_00748(algD)
SCYG: S1361_04630(algD)
SFEU: IM697_33530
SROI: IAG44_00725
SXN: IAG42_07115
SGJ: IAG43_29305
SHK: J2N69_02610
SINE: KI385_03390
SLF: JEQ17_08420
SAOV: G3H79_06935
SDUR: M4V62_06475
STAA: LDH80_04755
SLON: LGI35_03160
STEE: F3L20_11870
SYUN: MOV08_38485
SARG: HKX69_08010
SJN: RI060_36395
SCYN: N8I84_34940
SKG: KJK29_33180
SFP: QUY26_02885
STRZ: OYE22_28860
KBU: Q4V64_06025
SMIB: SMIR_07815
SCAJ: O1G22_01465
STRL: HEP84_37695
STSD: HEP87_38640
STRV: EZV63_33750
SMOD: POD33_22970
STBR: ABDE16_00175
SGRO: UBV09_26080
STAC: ABII15_36555
SSLI: R2D22_03205
STYI: C9F11_00600(algD)
SCIT: V2W30_37045
SSIR: WAB15_02205
SOKE: ACE1N8_27485
STGO: KBP30_35970
SHUG: ABVG11_30530
STRK: R2B38_37105
STHP: MQE23_11835
SBON: ACNNMR_38405
STHC: AY578_25290
ALIQ: AB5J87_05255
STWS: D1J60_02415
SFIL: ACQFX6_33730
KCH: O1G21_06125
KCM: ABWK59_01455
HEA: HL652_13685
ACH: Achl_2940
TEH: GKE56_16015
NDK: I601_0111(algD)
NOF: MF408_15695
NLB: P5P86_05690
KSL: OG809_26460
SRO: Sros_0655
NOA: BKM31_42710
NGN: LCN96_02635
NFS: OIE67_44765
BSD: BLASA_0423(algD)
AMD: AMED_0547(algD)
AMN: RAM_02805
AMM: AMES_0545(algD)
AMZ: B737_0546(algD)
AOI: AORI_0554(algD)
AJA: AJAP_36870(algD)
AMQ: AMETH_0542(ugd)
AMYB: BKN51_36975
AMYY: YIM_21485(algD)
AORI: SD37_38440
AACD: LWP59_02525
APRT: MUY14_33840
AROO: NQK81_20050
ATHM: L1857_05310
ARHD: VSH64_40365
AMOG: QRX60_08495
ACOR: LCL61_41965
ACAB: QRX50_04675
ANW: QP939_09660
AMYD: K1T34_21425
AMYE: MJQ72_38830
AMYS: CVV72_26080
ARHI: AB5I40_23660
PDX: Psed_1848
PBRO: HOP40_15385
PPEL: H6H00_14920
KUT: JJ691_61590(algD)
KBR: Q4V65_17680
PMAD: BAY61_02365
ACTY: OG774_25565
HAO: PCC7418_0427
NPU: Npun_F5503
NSH: GXM_00034
AMAT: ACPZ3T_16820
CTHE: Chro_0719
DAH: DAETH_33720
DMB: E5F05_17350
SCHV: BRCON_1950
 » show all
Reference
PMID:12705829
  Authors
Snook CF, Tipton PA, Beamer LJ
  Title
Crystal structure of GDP-mannose dehydrogenase: a key enzyme of alginate biosynthesis in P. aeruginosa.
  Journal
Biochemistry 42:4658-68 (2003)
DOI:10.1021/bi027328k
Reference
PMID:3108855
  Authors
Deretic V, Gill JF, Chakrabarty AM
  Title
Pseudomonas aeruginosa infection in cystic fibrosis: nucleotide sequence and transcriptional regulation of the algD gene.
  Journal
Nucleic Acids Res 15:4567-81 (1987)
DOI:10.1093/nar/15.11.4567
  Sequence
[pae:PA3540]
LinkDB

KEGG   ENZYME: 1.1.1.132
Entry
EC 1.1.1.132                Enzyme                                 
Name
GDP-mannose 6-dehydrogenase;
guanosine diphosphomannose dehydrogenase;
GDP-mannose dehydrogenase;
guanosine diphosphomannose dehydrogenase;
guanosine diphospho-D-mannose dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
GDP-D-mannose:NAD+ 6-oxidoreductase
Reaction(IUBMB)
GDP-D-mannose + 2 NAD+ + H2O = GDP-D-mannuronate + 2 NADH + 2 H+ [RN:R00880]
Reaction(KEGG)
R00880
Substrate
GDP-D-mannose [CPD:C00096];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
GDP-D-mannuronate [CPD:C00976];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Also acts on the corresponding deoxynucleoside diphosphate derivative as a substrate.
History
EC 1.1.1.132 created 1972
Pathway
ec00051  Fructose and mannose metabolism
ec00520  Amino sugar and nucleotide sugar metabolism
ec01100  Metabolic pathways
Orthology
K00066  GDP-mannose 6-dehydrogenase
Genes
LARE: HIV01_005960
PRE: PCA10_11880(algD) PCA10_38230(algD)
PFUW: KF707C_11170
POJ: PtoMrB4_26000(algD) PtoMrB4_46190
PLAL: FXN65_05555
PAE: PA3540(algD)
PAEV: N297_3663(algD)
PAEI: N296_3663(algD)
PAU: PA14_18580(algD)
PAG: PLES_14931(algD)
PAF: PAM18_1446(algD)
PNC: NCGM2_4665(algD)
PAEB: NCGM1900_2744(algD)
PDK: PADK2_06665
PSG: G655_07100
PRP: M062_18755
PAEP: PA1S_07720
PAER: PA1R_gp1358
PAEM: U769_07195
PAEL: T223_07435
PAES: SCV20265_1523
PAEU: BN889_03910(algD)
PAEG: AI22_26185
PAEC: M802_3660(algD)
PAEO: M801_3528(algD)
SECH: B18_00665
PCQ: PcP3B5_50680(algD)
PMUI: G4G71_08975
PNT: G5B91_26160
PAP: PSPA7_1605(algD)
PPAA: B7D75_07435
PPU: PP_1288(algD)
PPF: Pput_4437
PPG: PputGB1_4561
PPW: PputW619_0889
PPT: PPS_4403
PPB: PPUBIRD1_4273
PPI: YSA_03091
PPX: T1E_3168(algD)
PPUH: B479_22150
PPUT: L483_27235
PPUN: PP4_08000(algD)
PPUD: DW66_4794
PFV: Psefu_3880
PMON: X969_21685
PMOT: X970_21320
PPJ: RK21_00119
PMOL: CLJ08_08380 CLJ08_22925
PALD: LU682_024945
PIX: RIN61_07120
PWD: LOY45_11485 LOY45_22080
PSSG: CWR53_04400
PMOS: O165_013045 O165_018560
PST: PSPTO_1243(algD)
PSB: Psyr_1063
PSYR: N018_20355
PSP: PSPPH_1118(algD)
PSAV: PSA3335_09095
PAMG: BKM19_008085
PCI: PCH70_10130
PAVL: BKM03_07020
PVD: CFBP1590__4277(algD)
PCAB: JGS08_19525
PCOF: POR16_18925
PTRE: I9H09_05090
PSYI: MME58_05275
PAST: N015_05985
PLIJ: KQP88_04855
PFUV: NLK61_18730
PFL: PFL_1024(algD)
PPRC: PFLCHA0_c10440(algD)
PPRO: PPC_1062
PFE: PSF113_4752
PZA: HU749_024140
PFN: HZ99_11915
PFO: Pfl01_0960(algD)
PFS: PFLU_0990(algD)
PFC: PflA506_0970(algD)
PPZ: H045_01690
PFB: VO64_4071
PMAN: OU5_2447
PTV: AA957_09045
PCG: AXG94_09975
PVR: PverR02_05230
PAZO: AYR47_12230
POI: BOP93_04735
PRX: HRH33_05805
PMED: E3Z27_23120
PKR: AYO71_07540
PMUD: NCTC8068_04321(algD)
PTOL: I7845_05045
PMAB: U0037_04980
PBRE: QDY63_24165
PEXT: LUU92_05180
PFW: PF1751_v1c09480(algD)
PFF: PFLUOLIPICF703390
PFX: A7318_04290
PEN: PSEEN3453(algD-2) PSEEN4535(algD)
PBA: PSEBR_a4590
PBC: CD58_24305
PPUU: PputUW4_04471(algD)
PDR: H681_19425
PSV: PVLB_04235 PVLB_15470
PSK: U771_06125
PKC: PKB_0968(algD)
PCH: EY04_04520
PCZ: PCL1606_50710
PCP: JM49_25125
PCHP: C4K32_1103
PFZ: AV641_18510
PLQ: AA042_15150
PALK: PSAKL28_08740 PSAKL28_31810
PPV: NJ69_13830
PSES: PSCI_0721
PSEM: TO66_05210
PSEC: CCOS191_0912(algD1) CCOS191_2029(algD2)
PPSY: AOC04_15730
PSOS: POS17_1030
PFK: PFAS1_06330
PANR: A7J50_0992
PSET: THL1_1268 THL1_3804
PSIL: PMA3_24585
PYM: AK972_0838
PKE: DLD99_05160
PUM: HGP31_04975
PGG: FX982_00687
PGY: AWU82_19080 AWU82_29005
PSEJ: HNQ25_10170 HNQ25_19280
PVK: EPZ47_24330
PEZ: HWQ56_05050
PBZ: GN234_24015
PATA: JWU58_22750
PDW: BV82_3321 BV82_4690
PZE: HU754_006270
PMOE: HV782_005850
PSEP: C4K39_1041
PPII: QL104_05175
PDAN: PFZ56_10950
PVW: HU752_027430
PTRT: HU722_0006165
PXA: KSS93_07790
PSAM: HU731_021005
PTZ: HU718_005910
PQI: KH389_10480 KH389_22245
PSHH: HU773_022835
PXN: HU772_004420 HU772_009430
PHV: HU739_012710
PPRG: HU725_004085 HU725_014400
PANH: HU763_020330
PASG: KSS96_05695
PFAK: KSS94_04615
PMUY: KSS95_07475 KSS95_11760
PMAM: KSS90_04835 KSS90_09905
PAZE: KSS91_23845
PALV: KSS97_06295
PCAS: LOY40_05230
PORY: EJA05_04800
PWZ: J7655_04690(algD)
PTK: EXN22_12380 EXN22_22955
PTW: TUM18999_50120(algD)
PIE: HU724_005670
PWY: HU734_005480
PGF: J0G10_06075
PCAV: D3880_05550 D3880_05610
PJU: L1P09_20850
PIZ: LAB08_R50410
PPEG: KUA23_05150
PSII: NF676_05345
PSIH: LOY51_04705
PFIT: KJY40_05935
PASI: LG197_00315
PKM: PZ739_23450
PNB: NK667_22335
PSOA: PSm6_09920(algD)
PTAI: ICN73_10950
PKK: QQ992_23595
PKJ: Q1W70_05470 Q1W70_21865
PHYG: JTY93_21615
PHOM: KJF94_01550 KJF94_13595
PCUC: PSH97_04640
PTRL: OU419_22545(algD)
PPAE: LDL65_16250
PPAO: K3169_23650
PRHZ: CRX69_09220
PSJY: AA098_05025
PSKU: KUIN1_11040
PSHS: JJN09_02540
PHEF: PSH57_05225
PSLP: BHQ29_07820 BHQ29_17130
PLIS: NN484_01390
PSNC: C0058_26885
PFOU: OZ911_23940
PBEJ: PSH84_01850
PKV: QYQ93_05900
PSKP: KU43P_18940 KU43P_44560
PDEU: QEP73_14595
PQE: OSC50_19425
PSDT: NH234_05830
PCAA: V6L78_29655
PSIV: LZ023_33740
PSWO: SD196_21735(algD)
PMOR: PMm318_A01820
PTHV: CE140_22400
PSSX: DCC84_28260
PAGB: AWM79_03600
PSNS: CI807_11825
PSRU: CCX46_04885
PSNY: ACPFMA_05065
PSMD: K5R88_07535 K5R88_25895
PIM: OQ460_20600
PBAB: AAEO81_05605
PSYQ: HXW90_05545
PTUS: QC631_003745(algD) QC631_008855
PSLZ: B195_018025
PSSZ: DJ564_06000
PSDY: D6Z43_05910 D6Z43_13885
PSDU: C2E19_06315
PABN: ABDX87_09240
PSHN: LVW35_04895
PSND: NY023_23095
PVII: AABC73_05625
PSDD: N0B28_09975 N0B28_21635
PVQ: WOB24_01670
PSTP: ACOAPY_11905
PSHL: CS390_10215
PBER: HS968_06000
PSMP: ELQ88_29185
PSSJ: FXO12_12670
PDAL: PALTO1_09720(algD)
PMY: Pmen_1031 Pmen_1678
PMK: MDS_1082
PALL: UYA_04885 UYA_15320
PKH: JLK41_05220(algD)
PTY: JWV26_01370 JWV26_15965(algD)
PHF: NLY38_05240(algD) NLY38_16715
PCHE: QYM18_12805(algD) QYM18_23005(algD)
ECOP: L0Y47_05480(algD)
AVN: Avin_10970(algD)
AVL: AvCA_10970(algD)
AVD: AvCA6_10970(algD)
ACX: Achr_31180(algD)
EAZ: JHT90_07865
ENTO: MTZ49_11930
PDEN: F1C79_17950
PPHA: BVH74_05210
PALC: A0T30_11805
PCAM: HNE05_07125
MSR: AU15_13665
MACA: J2887_18610
GAG: Glaag_2800
PMES: FX988_01104
PAT: Patl_1531
HMI: soil367_08790
ALKM: NKI27_00790
CEG: D0C16_11005
GIL: NHM04_15470
MNY: R50073_15990
HAUI: ABXT62_16600
MEIY: MIN45_P0136
THIM: KFB96_07615
TFRI: Thiofri_03630(algD)
ABO: ABO_0384(algD)
ALN: AS19_03970
GSN: YC6258_00963
OME: OLMES_2098 OLMES_4477
TAU: Tola_1407
SVA: SVA_1550
REV: HUE57_13005
PLG: NCTC10937_04283(algD)
RFR: Rfer_0673
PAQA: K9V56_012855 K9V56_012880
PAIS: PFX98_20965
ATER: MW290_14625
JAG: GJA_3986(algD)
JAL: BZG29_08185
JAS: FJQ89_25120
JLV: G3257_08340
JRI: P9875_08610
JAE: OPV09_08525
MNR: ACZ75_11680
MASY: DPH57_12210
MENY: LSQ66_04000
MASZ: C9I28_09765
MFLA: GO485_23875
MPLI: E1742_23455
TCT: PX653_13240
PLUE: EWM63_05620
EHB: E7V67_006890
NDM: RBH92_05285
MUV: FIT94_04050
EBA: ebA4268(algD)
AZO: azo3269(algD)
AOA: dqs_3408
THAJ: AAG895_05040
ACOM: CEW83_18780
APP: CAP2UW1_0858 CAP2UW1_1431
ACOG: HWD57_11430
AMAX: ABWH92_04635
ARUI: G6M88_17210
RHL: LPU83_pLPU83d0171(algD1) LPU83_pLPU83d1236(algD3)
RGR: FZ934_26065
RROS: D4A92_02485 D4A92_22670
RSUL: N2599_29805
RHIU: IM739_19050
BJA: blr6296(blr6296)
BRA: BRADO7047
BRS: S23_62720
BRC: BCCGELA001_11045
BIC: LMTR13_08410
BRK: CWS35_18850
BRQ: CIT40_06180
BSYM: CIT39_05020
BARH: WN72_18950
BEL: BE61_69060
BSEP: HAP48_0031560
BQB: J4P68_0032835
BAUT: QA635_27835
BBRA: QA636_29730
BPAH: QA639_16165
BRAB: RX331_09160
BRAH: RX329_27910
TARV: FIU28_16890
MNO: Mnod_5882
METI: DK427_06650
MTEZ: HPT29_006150
BID: Bind_3885
MPAR: F7D14_18240
MAAD: AZF01_02675
MMED: Mame_02304(algD)
MLUT: JET14_03725
JAV: OXU80_00280
RBM: TEF_19885
LABR: CHH27_22980
LABP: FJ695_16660
RPOP: K1718_15110
ACUT: MRB58_00060
RUY: NOR97_20535
DSH: Dshi_1896(algD)
MALG: MALG_02776
CON: TQ29_00725
YPAC: CEW88_18640
YAN: AYJ57_24995
SULZ: C1J03_23160
TOM: BWR18_20775
THAA: CFI11_06320 CFI11_06490
RMH: LVO79_06000
HAT: RC74_06375
LSAL: KBK07_17255
TRY: QF118_01765
THW: BMG03_12925
TLB: RPE78_12915
YPHY: AABB29_07900
YRH: AABB31_14955
LIT: FPZ52_00565
PPRU: FDP22_22880
POZ: I0K15_05930
CACT: HZ995_12210
HDH: G5B40_09200
AMYL: QBD29_07855
FAQ: G5B39_18330
NAR: Saro_3220
NAEO: ACLIMP_18845
SPHI: TS85_22025
SSAN: NX02_04640
ACOB: P0Y56_12580
EGN: BMF35_a0516
ERF: FIU90_00265(algD)
ERYT: KDC96_15245
PHZ: CHX26_00290
POT: E2E27_01460
PORU: KVF90_00385
RAP: RHOA_PB0089(algD)
HTQ: FRZ44_03090(algD)
HADH: FRZ61_03380(algD)
MVP: P4R82_19690
SNEA: NBZ79_19285
MINW: ACMVY4_02945
NIS: NIS_0191
CMED: FE773_08555
CPAF: C6V80_01890
DVE: DESUT3_23450(algD)
DSA: Desal_3469
DTO: TOL2_C36540(algD)
BMX: BMS_2990
STI: Sthe_1134
SLOM: PXH66_05790
OLV: ACMYLB_10770
ROO: G5S37_25645
FPES: NXS98_06570
AHEL: Q31a_57060(algD)
SMAM: Mal15_36880(algD)
MRI: Mal4_03640(algD)
SDYN: Mal52_06430(algD)
SCHL: QJS52_01950
SSPE: ACGY09_01855
LALU: SH248x_001646
FTJ: FTUN_5650
ABA: Acid345_3792
TRS: Terro_2830
ADIN: H7849_05985
OBV: P8935_13600
SUS: Acid_0553
LUB: TBR22_A24300(algD)
BDO: EL88_09425
NKO: Niako_7100
CMR: Cycma_0720
EMAI: KZP23_20245
SPIB: G8759_29085
SRHO: HH216_01470
SENF: GJR95_15585
SPIO: WBJ53_24135
DSN: HWI92_00320
DEND: ACN9ML_00320
FIB: A6C57_20705
PKO: PKOR_16530
CLIT: OQ292_40240
PRHO: PZB74_20200
TPEL: P0M28_17740
CNQ: PZB72_28250
ZGA: ZOBELLIA_1984(algD)
MLIL: QLS71_002625
PPON: MUN68_016515
CACI: CLOAM0663
TAM: Theam_0797
NMV: NITMOv2_2630(algD)
NNEO: PQG83_09560
PARH: I5S86_05480
PHEX: L0M14_20510
LBP: V1224_13340
HSG: HPPSJP_3770(rkpK)
MSM: MSMEG_5957(algD)
MSG: MSMEI_5797
MSB: LJ00_29460
MSN: LI99_29465
MSH: LI98_29470
MVA: Mvan_1699
MAUS: JN090_07325
MSP: Mspyr1_41390
MNE: D174_24385
MYN: MyAD_23925
MTY: MTOK_31270(algD)
MSAR: MSAR_24600(algD)
MANY: MANY_49000(algD)
MPOF: MPOR_19690
MGO: AFA91_10990 AFA91_29875
MRF: MJO55_24360
MDF: K0O62_25565
MFRE: EXE63_09795
MFLU: HZU40_32750
NHU: H0264_19875
ROP: ROP_57960(algD)
RKO: JWS14_31405
RHOY: QNA09_05105
TOY: FO059_04060
SCO: SCO0382(SCF62.08)
SGRF: SGFS_035730
SCB: SCAB_23351
SVL: Strvi_5599
SHY: SHJG_7006
SHO: SHJGH_6766
SRC: M271_40840
SBH: SBI_09543
SVE: SVEN_7199
SLV: SLIV_36030(algD)
SVT: SVTN_36100
STRE: GZL_08291
SLD: T261_7968
SPRI: SPRI_2000
STRF: ASR50_26930
SPAV: Spa2297_31800
STRT: A8713_24610
SCLF: BB341_00345
SGS: AVL59_31095
SALW: CP975_03365
SGM: GCM10017557_19510
SGRS: V9K83_07275
SLS: SLINC_8140
SNR: SNOUR_37270(algD)
SALU: DC74_1121
SALL: SAZ_06100
SPLU: LK06_025850
STRD: NI25_00640
SSIA: A7J05_09315
SGV: B1H19_04475
SALF: SMD44_08071(algD)
STRO: STRMOE7_01550
SFK: KY5_0166c
SGE: DWG14_01282(algD_2)
SLK: SLUN_34570
SQZ: FQU76_01535
SCYA: EJ357_37150
SKA: CP970_42095
SVR: CP971_03305
SFY: GFH48_34990
SBY: H7H31_29485
SFUG: CNQ36_29650
STSU: B7R87_32065
SCHA: CP983_11050
SGX: H4W23_37670
SCOE: CP976_05755
SSPB: CP982_01460
SHUN: DWB77_00748(algD)
SCYG: S1361_04630(algD)
SFEU: IM697_33530
SROI: IAG44_00725
SXN: IAG42_07115
SGJ: IAG43_29305
SHK: J2N69_02610
SINE: KI385_03390
SLF: JEQ17_08420
SAOV: G3H79_06935
SDUR: M4V62_06475
STAA: LDH80_04755
SLON: LGI35_03160
STEE: F3L20_11870
SYUN: MOV08_38485
SARG: HKX69_08010
SJN: RI060_36395
SCYN: N8I84_34940
SKG: KJK29_33180
SFP: QUY26_02885
STRZ: OYE22_28860
KBU: Q4V64_06025
SMIB: SMIR_07815
SCAJ: O1G22_01465
STRL: HEP84_37695
STSD: HEP87_38640
STRV: EZV63_33750
SMOD: POD33_22970
STBR: ABDE16_00175
SGRO: UBV09_26080
STAC: ABII15_36555
SSLI: R2D22_03205
STYI: C9F11_00600(algD)
SCIT: V2W30_37045
SSIR: WAB15_02205
SOKE: ACE1N8_27485
STGO: KBP30_35970
SHUG: ABVG11_30530
STRK: R2B38_37105
STHP: MQE23_11835
SBON: ACNNMR_38405
STHC: AY578_25290
ALIQ: AB5J87_05255
STWS: D1J60_02415
SFIL: ACQFX6_33730
KCH: O1G21_06125
KCM: ABWK59_01455
HEA: HL652_13685
ACH: Achl_2940
TEH: GKE56_16015
NDK: I601_0111(algD)
NOF: MF408_15695
NLB: P5P86_05690
KSL: OG809_26460
SRO: Sros_0655
NOA: BKM31_42710
NGN: LCN96_02635
NFS: OIE67_44765
BSD: BLASA_0423(algD)
AMD: AMED_0547(algD)
AMN: RAM_02805
AMM: AMES_0545(algD)
AMZ: B737_0546(algD)
AOI: AORI_0554(algD)
AJA: AJAP_36870(algD)
AMQ: AMETH_0542(ugd)
AMYB: BKN51_36975
AMYY: YIM_21485(algD)
AORI: SD37_38440
AACD: LWP59_02525
APRT: MUY14_33840
AROO: NQK81_20050
ATHM: L1857_05310
ARHD: VSH64_40365
AMOG: QRX60_08495
ACOR: LCL61_41965
ACAB: QRX50_04675
ANW: QP939_09660
AMYD: K1T34_21425
AMYE: MJQ72_38830
AMYS: CVV72_26080
ARHI: AB5I40_23660
PDX: Psed_1848
PBRO: HOP40_15385
PPEL: H6H00_14920
KUT: JJ691_61590(algD)
KBR: Q4V65_17680
PMAD: BAY61_02365
ACTY: OG774_25565
HAO: PCC7418_0427
NPU: Npun_F5503
NSH: GXM_00034
AMAT: ACPZ3T_16820
CTHE: Chro_0719
DAH: DAETH_33720
DMB: E5F05_17350
SCHV: BRCON_1950
 » show all
Reference
1  [PMID:14245351]
  Authors
PREISS J.
  Title
SUGAR NUCLEOTIDE REACTIONS IN ARTHROBACTER. II. BIOSYNTHESIS OF GUANOSINE DIPHOSPHOMANNURONATE.
  Journal
J Biol Chem 239:3127-32 (1964)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.132
IUBMB Enzyme Nomenclature: 1.1.1.132
ExPASy - ENZYME nomenclature database: 1.1.1.132
BRENDA, the Enzyme Database: 1.1.1.132
CAS: 37250-63-8
LinkDB

KEGG   REACTION: R00880
Entry
R00880                      Reaction                               
Name
GDP-D-mannose:NAD+ 6-oxidoreductase
Definition
GDP-mannose + H2O + 2 NAD+ <=> GDP-D-mannuronate + 2 NADH + 2 H+
Equation
C00096 + C00001 + 2 C00003 <=> C00976 + 2 C00004 + 2 C00080
Reaction class
RC00001  C00003_C00004
RC00291  C00096_C00976
Enzyme
1.1.1.132
Pathway
rn00051  Fructose and mannose metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.132
     R00880  GDP-mannose + H2O + 2 NAD+ <=> GDP-D-mannuronate + 2 NADH + 2 H+
Orthology
K00066  GDP-mannose 6-dehydrogenase [EC:1.1.1.132]
Other DBs
RHEA: 21731
LinkDB

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