KEGG   ORTHOLOGY: K00290
Entry
K00290                      KO                                     
Symbol
LYS1
Name
saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]
Pathway
map00300  Lysine biosynthesis
map00310  Lysine degradation
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Reaction
R00715  N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-lysine-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K00290  LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming)
   00310 Lysine degradation
    K00290  LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.7  saccharopine dehydrogenase (NAD+, L-lysine-forming)
     K00290  LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming)
Other DBs
GO: 0004754
Genes
NVE: 5513834
EPA: 110253051
ATEN: 116297853 116298760 116300891 116300965
ADF: 107350380
AMIL: 114957762
MCAZ: 138019110 138019805
MFOO: 137996124 137996132
PDAM: 113665974 113665975
SPIS: 111333439 111333523 111335282 111337694
RES: 135690066
SCE: YIR034C(LYS1)
SEUB: DI49_2813
SPAO: SPAR_I01890
AGO: AGOS_ACR167C
ERC: Ecym_5636
KLA: KLLA0_E07987g
KMX: KLMA_40368(LYS1)
LTH: KLTH0C00594g
VPO: Kpol_1057p13
ZRO: ZYRO0D00594g
CGR: 2887663(GVI51_F06479)
NCS: NCAS_0A08650(NCAS0A08650)
NDI: NDAI_0G05090(NDAI0G05090)
TPF: TPHA_0N01860(TPHA0N01860)
TBL: TBLA_0C01000(TBLA0C01000)
TGB: HG536_0G00200
TDL: TDEL_0B07590(TDEL0B07590)
KAF: KAFR_0A00160(KAFR0A00160)
KNG: KNAG_0H00170(KNAG0H00170) KNAG_0M02400(KNAG0M02400)
ZMK: HG535_0H00220
SLUD: SCDLUD_003070
DHA: DEHA2C07018g
PIC: PICST_86170(LYS1)
PGU: PGUG_05365
SPAA: SPAPADRAFT_147229(LYS1)
LEL: PVL30_004380(LYS1_2)
LBG: 92210479(LODBEIA_P52830)
CAL: CAALFM_C405320WA(LYS1)
CTP: CTRG_03875
COT: CORT_0B00970
CDU: CD36_44980
CTEN: 18246997(LYS1_2) 18248054(LYS1_1)
CLU: CLUG_04507
CLUS: A9F13_25g00627
CAUR: CJI96_0001742
ASAU: 88175374(PUMCH_004313)
PPA: PAS_chr1-1_0447
PKZ: C5L36_0C04460
BNN: FOA43_002432(LYS1)
BBRX: BRETT_000252(LYS1)
OPA: HPODL_00111
YLI: 2907616(YALI2_C00436g)
SLB: AWJ20_1568(LYS1)
NCR: NCU03118
NTE: NEUTE1DRAFT91293(NEUTE1DRAFT_91293)
PAN: PODANSg5796
PBEL: QC761_110980(LYS1)
PPSD: QC762_110980(LYS1)
PPSP: QC763_110980(LYS1)
PPSA: QC764_110980(LYS1)
TTT: THITE_2113543
MTM: MYCTH_2088454
CTHR: CTHT_0060440
RTHE: 98123094(VTJ83DRAFT_2205)
MGR: MGG_01359
PPEI: PpBr36_00869
PGRI: PgNI_04166
TMN: UCRPA7_104
SSCK: SPSK_03427
FGR: FGSG_10925
FPU: FPSE_11246
FPOA: FPOAC1_009666
FVN: FVRRES_10306
FVR: FVEG_11605 FVEG_16154
FOX: FOXG_12862
NHE: NECHADRAFT_93245
FFC: NCS54_00646800
FKR: NCS57_00687100
FMU: J7337_010011 J7337_010372
TRE: TRIREDRAFT_119788
TRR: M419DRAFT_135482
TATV: 25780310(TrAtP1_008689)
TASP: 36607787(TrAFT101_002745)
MAW: 19254001(LYS1_6)
MAJ: MAA_06003
MBRN: 26238428(lys3)
PCHM: VFPPC_07774
UVI: 66060834(UV8b_00056)
CMT: CCM_03749 CCM_04910
AMUS: LMH87_004323
PLJ: 28883961(PLICBS_005245)
PTKZ: JDV02_004112(LYS1)
DCON: 63712899(DCS_00256)
VAL: VDBG_07364
VDA: VDAG_06069
CFJ: CFIO01_08377
CLUP: CLUP02_13705
CHIG: CH63R_05808
CDET: 87948791(CDEST_12291)
SAPO: SAPIO_CDS0173
ELA: UCREL1_5874
PFY: PFICI_00199
SSL: SS1G_06166
BFU: BCIN_05g04270(Bclys1)
MBE: MBM_03432
PSCO: LY89DRAFT_604497 LY89DRAFT_651629
GLZ: GLAREA_10832
ANI: ANIA_02873
AFM: AFUA_3G11710
ACT: ACLA_039590
NFI: NFIA_065620
AOR: AO090003000729
ANG: An02g07500
AFV: AFLA_000953
ALUC: AKAW2_10619A(LYS1_1)
ACHE: ACHE_21163A(LYS1_2)
APUU: APUU_30693A(LYS1_2)
PCS: N7525_000851
PDP: PDIP_74380
POU: POX_b03123
PPSF: 300792871(PFLUO_LOCUS6778)
TMF: EYB26_000569
TRG: TRUGW13939_04035
CIM: CIMG_00116
CPW: 9692265(LYS1_1)
URE: UREG_00224
ABE: ARB_05726
TVE: TRV_03009
PBL: PAAG_05847
PBN: PADG_06144
AJE: HCAG_01145
BGH: BDBG_06619
PNO: SNOG_13323
PTE: PTT_12058
PTRR: 6343292(PtrM4_120610)
BZE: COCCADRAFT_9863
BSC: COCSADRAFT_38405
BOR: COCMIDRAFT_104289
AALT: CC77DRAFT_171007
ADAC: 96086569(ACET3X_006247)
ARAB: EKO05_0000880
ZTR: MYCGRDRAFT_60912
PFJ: MYCFIDRAFT_49771
FFU: CLAFUR5_05047
CBET: CB0940_11237
BCOM: BAUCODRAFT_152629
NPA: UCRNP2_8755
TML: GSTUM_00005842001
SPO: 2541500(lys3)
SOM: SOMG_01598(lys3)
CNE: CND06290
CNB: CNBD0140
CNG: CNAG_06849
CGI: CGB_I0170W
CDEU: CNBG_5912
CDEC: 89991859(IAS62_005089)
CTEG: 91992219(I308_105363)
CBAS: 91983682(I312_103637)
CDEP: 91088192(L203_103982)
KMG: 30166258(I203_102327)
KNE: 92179947(IAR55_002689)
KDJ: 28969222(I303_105031)
KBI: 30210583(I302_106554)
KPIN: 30170490(I206_104587)
KSH: 87956755(IL334_004624)
KER: 91101605(V865_002801)
KSN: 43590172(CI109_102802)
KBO: 90015077(L199_004093)
KEP: 91094388(L201_003718)
TMS: TREMEDRAFT_37417
TASA: A1Q1_01558
CCAC: CcaHIS019_0608570(LYS1)
TVS: TRAVEDRAFT_55646
DSQ: DICSQDRAFT_95061
PCO: PHACADRAFT_84219
SHS: STEHIDRAFT_123797
HIR: HETIRDRAFT_437937
PSQ: PUNSTDRAFT_48486
ADL: AURDEDRAFT_111611
FME: FOMMEDRAFT_129025
GTR: GLOTRDRAFT_68913
RSX: RhiXN_11432
LBC: LACBIDRAFT_228788
CCI: CC1G_03693
ABP: AGABI1DRAFT96692(AGABI1DRAFT_96692)
ABV: AGABI2DRAFT133180(AGABI2DRAFT_133180)
PCUB: JR316_0000810
MPR: MPER_10902
MRR: Moror_145
MORE: E1B28_001264
SCM: SCHCO_02612998(SCHCODRAFT_02612998)
CPUT: CONPUDRAFT_86509
SLA: SERLADRAFT_480237
WSE: WALSEDRAFT_59278
WIC: J056_002071
UMA: UMAG_04268
PFP: PFL1_03275
SGRA: EX895_002018
MGL: MGL_0554
MRT: MRET_4335
MSYM: MSY001_3457
PGR: PGTG_12721
PTRC: PtA15_6A217
PSTR: Pst134EA_003218
MLR: MELLADRAFT_117783
RIE: OCT59_008247
MBR: MONBRDRAFT_32342
SRE: PTSG_00686
ACAN: ACA1_399240
NGR: NAEGRDRAFT_78399
VBR: A6E01_07465
PPR: PBPRB1102(SAV1788)
PGB: H744_1c1753
SVO: SVI_3927
SPSW: Sps_03208
SEUR: FM038_002230
CBER: B5D82_14350
LSD: EMK97_10165
TPSY: RGQ13_04340
TFT: RI844_08680
MMAA: FR932_02790
GAI: IMCC3135_26915
BGE: BC1002_6948
PSPW: BJG93_27770
PSAA: QEN71_40330
SIL: SPO3307(lkr)
SIT: TM1040_0107
RUA: D1823_16465
RUT: FIU92_14995(ald2)
RCON: K3740_16350
RUY: NOR97_13955
JAN: Jann_4015
RDE: RD1_0698
RLI: RLO149_c038450
RPON: G3256_01760
RFU: ROLI_004280
PGA: PGA1_c32690
PGL: PGA2_c30960
PGD: Gal_03330
PHP: PhaeoP97_03177
PPIC: PhaeoP14_03069
PHQ: D1820_11140
PHAE: N1037_19420
OAT: OAN307_c45970
OAR: OA238_c40540
OTM: OSB_29950(ald_3)
OCT: FTO60_14855
LMD: METH_00175
LEJ: ETW24_00170
LAQU: R2C4_17070
LEV: ETW23_19120
LCAE: K3721_00175
LEIM: K3557_17715
MALG: MALG_00109
YPAC: CEW88_14660
YAN: AYJ57_17005
TPRO: Ga0080559_TMP3190
PABY: Ga0080574_TMP1229
SULZ: C1J03_20910
SULI: C1J05_00895
SULD: B5M07_02275
SPOT: G6548_00495
SMED: JNX03_15105
SINL: DSM14862_00456
SFAV: PL335_02115
SDUB: R1T39_12530
SULB: IV89_000674
SULY: ABM428_00305
SULP: AADW22_00330
SPSE: SULPSESMR1_02884
TOM: BWR18_18240
TATE: ACMHLQ_09965
TATY: ACERHN_12560
RMM: ROSMUCSMR3_00818(ald)
ROK: RAK1035_3690
RID: RIdsm_04909
ROM: EI983_01020
ROH: FIU89_01100
RPEL: N7U68_11230
RRL: RZS32_009170
AHT: ANTHELSMS3_00159
SAGU: CDO87_06655
SSTL: ABFK29_19540
SAGZ: QNI11_02295
THAA: CFI11_21225
OCD: FHY55_20110
MALU: KU6B_07830 KU6B_07840
TGL: HFZ77_09150
HAT: RC74_05215
PALX: GQA70_03565
LSAL: KBK07_00185
LALG: LentiSH36_02331
TRY: QF118_04975
MARU: FIU81_14385
RED: roselon_00774
ASCA: QEZ52_02105
ACLD: ACIRQ6_00225
SEOH: ACMUJL_10965
MATG: ACMVPR_06955
RPOH: ABWH90_18540
RSP: RSP_1086(sdh)
RSH: Rsph17029_2749
RSQ: Rsph17025_2942
RSK: RSKD131_2484
CAZT: LV780_13175
RBL: B6K69_08800
FYT: QF092_13805
PDE: Pden_2709
PYE: A6J80_08360
PCON: B0A89_05955
PZH: CX676_12800
PARO: CUV01_08965
PARS: DRW48_02850
PARR: EOJ32_01205
PAAK: FIU66_12690
PKD: F8A10_10780
PPAN: ESD82_10970
PLIA: E4191_00265
PSAN: HGN31_07870
PMAU: CP157_00222(ald2)
PFIS: JHX87_11615
PAEX: JHW48_01060
PSTL: JHW45_02550
PVER: E3U25_20890
PAEZ: PAE61_16360
PDIM: PAF18_13035
PFEO: E3U26_09160
PHOI: ACLISE_13210
PTP: RCA23_c28820
RMB: K529_000605
TSCO: R1T40_15095
DON: BSK21_12700
MALC: QQG91_05260
RBZ: B9057_12425
LVS: LOKVESSMR4R_03787(ald)
YAG: AABB28_14950
YRH: AABB31_05080
GEH: HYN69_16605
TAW: EI545_09415
SEDI: EBB79_19195
PPSO: QPJ95_09065
PSEB: EOK75_10440
PAED: G5B38_12720
PAMO: BAR1_02320
PPAF: I8N54_00780
CACT: HZ995_08090
THAS: C6Y53_08610
GCE: KYE46_02815
GYJ: AADW23_02475
NSM: JO391_17545
ACRO: K3J57_12315
AMYL: QBD29_07465
RHOC: QTA57_03865
PBAE: P8S53_01660
MANH: LA6_004788
RBX: I3V23_07855
ECOG: FIV45_07485
PAQI: KW060_12350
BMX: BMS_1042 BMS_3023
HAX: BALOs_2120 BALOs_2686
SMA: SAVERM_1788
SGRF: SGFS_028790
SCB: SCAB_15871
SHY: SHJG_7558
SHO: SHJGH_7319
SDV: BN159_1824
SCI: B446_30345
SCX: AS200_10130
SRW: TUE45_07193
STSI: A4E84_34035
SGM: GCM10017557_34240(sdh)
SPHW: NFX46_11815
SLS: SLINC_7047
SLX: SLAV_08715 SLAV_39975
SNZ: DC008_29075
SGE: DWG14_01558
SQZ: FQU76_11665
SCYA: EJ357_39670
SHAW: CEB94_34915
SGAL: CP966_30450
SVR: CP971_29815
SFY: GFH48_08890
SAQU: EJC51_38675
SPHV: F9278_40085
STSU: B7R87_11310
SCHA: CP983_07345
SCOE: CP976_36405
STUI: GCM10017668_59820(sdh)
SCYG: S1361_32840
SROI: IAG44_06805
SLF: JEQ17_09520
SDEC: L3078_38375
SAKB: K1J60_06845
SCAE: IHE65_06390
SCIR: STRCI_006728
SARG: HKX69_04965
SJN: RI060_06475
SCYN: N8I84_33580
SHAU: K9S39_10125
SKG: KJK29_04865
SCOA: QU709_05970
KBU: Q4V64_46265
SPRF: K4G22_20345
STPB: QR97_13725
SMIB: SMIR_02015
STRL: HEP84_42470
SMOD: POD33_32735
STGO: KBP30_08025
STRK: R2B38_35845
STJL: ACE1OA_06755
KCH: O1G21_10300
JME: EEW87_004530
PHW: G7075_01900
PEI: H9L10_09510
SERJ: SGUI_2172
ORN: DV701_10960
SERW: FY030_15380
NSN: EXE58_03105
NPI: G7071_01015
NRO: K8W59_18355
NPS: KRR39_09915
MGG: MPLG2_1577
ACYN: ORV05_12950
APRE: CNX65_17945
AMI: Amir_3541
AAUR: V5P93_007099
UME: RM788_44440
SAQ: Sare_1048
MCAY: PVK37_25730
VET: ACQVFL_20985
PLK: CIK06_17705
NAV: JQS30_08335
EKE: EK0264_08680
 » show all
Reference
PMID:4287986
  Authors
Saunders PP, Broquist HP
  Title
Saccharopine, an intermediate of the aminoadipic acid pathway of lysine biosynthesis. IV. Saccharopine dehydrogenase.
  Journal
J Biol Chem 241:3435-40 (1966)
  Sequence
[sce:YIR034C]
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