KEGG   ORTHOLOGY: K00293
Entry
K00293                      KO                                     
Symbol
LYS9
Name
saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10]
Pathway
map00300  Lysine biosynthesis
map00310  Lysine degradation
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Reaction
R02315  N6-(L-1,3-dicarboxypropyl)-L-lysine:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K00293  LYS9; saccharopine dehydrogenase (NADP+, L-glutamate forming)
   00310 Lysine degradation
    K00293  LYS9; saccharopine dehydrogenase (NADP+, L-glutamate forming)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.10  saccharopine dehydrogenase (NADP+, L-glutamate-forming)
     K00293  LYS9; saccharopine dehydrogenase (NADP+, L-glutamate forming)
Other DBs
COG: COG1748
GO: 0004755
Genes
SHON: 118994002
NVE: 116616792
SCE: YNR050C(LYS9)
SEUB: DI49_4783
SPAO: SPAR_N03520
AGO: AGOS_ABR116C
ERC: Ecym_7008
KLA: KLLA0_C18744g
KMX: KLMA_40016(LYS9)
LTH: KLTH0A07590g
VPO: Kpol_1028p12
ZRO: ZYRO0D17578g
CGR: 2886722(LYS9)
NCS: NCAS_0A05670(NCAS0A05670)
NDI: NDAI_0K02690(NDAI0K02690)
TPF: TPHA_0M02120(TPHA0M02120)
TBL: TBLA_0F00190(TBLA0F00190)
TGB: HG536_0A09500
TDL: TDEL_0A07910(TDEL0A07910)
KAF: KAFR_0C04810(KAFR0C04810)
KNG: KNAG_0D00180(KNAG0D00180)
ZMK: HG535_0F00210
SLUD: SCDLUD_003780
DHA: DEHA2F17424g
PIC: PICST_70210(LYS9)
PGU: PGUG_04239
SPAA: SPAPADRAFT_62366
LEL: PVL30_003814(LYS9)
LBG: 92208409(LODBEIA_P32130)
CAL: CAALFM_C306590WA(LYS9)
CTP: CTRG_05710
COT: CORT_0C00740
CDU: CD36_86570
CTEN: 18248562(LYS9)
CLU: CLUG_04206
CLUS: A9F13_04g03179
CAUR: CJI96_0004931
ASAU: 88173721(PUMCH_002657)
PPA: PAS_chr3_0528
PKZ: C5L36_0E03900
BNN: FOA43_001036(LYS9)
BBRX: BRETT_003666(LYS9)
OPA: HPODL_04616
YLI: 2910249(YALI2_D00480g)
NCR: NCU03748
NTE: NEUTE1DRAFT58317(NEUTE1DRAFT_58317)
SMP: 10809790(SMAC4_02595)
PAN: PODANSg8147
PBEL: QC761_203550(LYS9)
PPSD: QC762_203550(LYS9)
PPSP: QC763_203550(LYS9)
PPSA: QC764_203550(LYS9)
TTT: THITE_2050253 THITE_2107047
MTM: MYCTH_2300877
CTHR: CTHT_0065790
RTHE: 98127011(VTJ83DRAFT_5734)
MGR: MGG_17041
PPEI: PpBr36_10814
PGRI: PgNI_00200
TMN: UCRPA7_3100
SSCK: SPSK_03190
FGR: FGSG_00346
FPU: FPSE_00004 FPSE_09212
FPOA: FPOAC1_000362(LYS3) FPOAC1_003319
FVN: FVRRES_00498
FVR: FVEG_00801
FOX: FOXG_00713
NHE: NECHADRAFT_101578 NECHADRAFT_92326
FFC: NCS54_00466900 NCS54_01134500
FKR: NCS57_00474100 NCS57_01125000
FMU: J7337_001193(LYS3)
TRE: TRIREDRAFT_123631
TRR: M419DRAFT_88293
TATV: 25782360(TrAtP1_006292)
TASP: 36619383(LYS3)
MAW: 19245701(LYS9_1)
MAJ: MAA_08309
MBRN: 26247571(LYS3)
PCHM: VFPPC_16295
UVI: 66066376(UV8b_05599)
CMT: CCM_00396
AMUS: LMH87_000649
PLJ: 28889964(PLICBS_008631)
PTKZ: JDV02_005266(LYS9)
DCON: 63716042(DCS_03399)
VAL: VDBG_04207
VDA: VDAG_01433
CFJ: CFIO01_01988 CFIO01_06768
CLUP: CLUP02_08240
CHIG: CH63R_03270 CH63R_08861
CDET: 87938109(CDEST_01606) 87950038(CDEST_13538)
SAPO: SAPIO_CDS0514
ELA: UCREL1_7945 UCREL1_8042
PFY: PFICI_12081
SSL: SS1G_13213
BFU: BCIN_03g09280(Bclys9)
MBE: MBM_03741
PSCO: LY89DRAFT_705797
GLZ: GLAREA_00865 GLAREA_05240
ANI: ANIA_05601
AFM: AFUA_4G11340
ACT: ACLA_003400 ACLA_050430
NFI: NFIA_105250
AOR: AO090001000233 AO090003001086
ANG: An01g13590 An04g05260
AFV: AFLA_000585 AFLA_008579
ALUC: AKAW2_10277A AKAW2_51500S(LYS3)
ACHE: ACHE_10568A(LYS3)
APUU: APUU_40960S(LYS3)
PCS: N7525_000842 N7525_005645
PDP: PDIP_34140
POU: POX_a01490
PPSF: 300795351(PFLUO_LOCUS9009)
TMF: EYB26_005353
TRG: TRUGW13939_02837
CIM: CIMG_01555
CPW: 9691150(LYS3)
URE: UREG_05275
ABE: ARB_02329
TVE: TRV_04693
PBL: PAAG_02693
PBN: PADG_01718
AJE: HCAG_01575
BGH: BDBG_07199
PNO: SNOG_09324
PTE: PTT_10655
PTRR: 6339704(PtrM4_014470) 6344550(PtrM4_047610)
BZE: COCCADRAFT_8652
BSC: COCSADRAFT_188437
BOR: COCMIDRAFT_39282
AALT: CC77DRAFT_143741
ADAC: 96089000(ACET3X_008678)
ARAB: EKO05_0003172
ZTR: MYCGRDRAFT_110462(LYS9)
PFJ: MYCFIDRAFT_49608 MYCFIDRAFT_54301
FFU: CLAFUR5_07080
CBET: CB0940_06498
BCOM: BAUCODRAFT_33041
NPA: UCRNP2_5529
TML: GSTUM_00000988001
SPO: 2540908(lys9)
SOM: SOMG_00104(lys9)
SHS: STEHIDRAFT_129850
CPUT: CONPUDRAFT_168017
RIE: OCT59_020587
MBR: MONBRDRAFT_34020
DDI: DDB_G0285267(sdh)
PTM: GSPATT00022932001
KKO: Kkor_1620
KPD: CW740_04755
 » show all
Reference
PMID:7935367
  Authors
Feller A, Dubois E, Ramos F, Pierard A
  Title
Repression of the genes for lysine biosynthesis in Saccharomyces cerevisiae is caused by limitation of Lys14-dependent transcriptional activation.
  Journal
Mol Cell Biol 14:6411-8 (1994)
DOI:10.1128/mcb.14.10.6411
  Sequence
[sce:YNR050C]
Reference
PMID:10714900
  Authors
Zabriskie TM, Jackson MD.
  Title
Lysine biosynthesis and metabolism in fungi.
  Journal
Nat Prod Rep 17:85-97 (2000)
DOI:10.1039/A801345D
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