Saccharomyces cerevisiae (budding yeast): YNR050C
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Entry
YNR050C CDS
T00005
Symbol
LYS9, LYS13
Name
(RefSeq) saccharopine dehydrogenase (NADP+, L-glutamate-forming)
KO
K00293
saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:
1.5.1.10
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00300
Lysine biosynthesis
sce00310
Lysine degradation
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01230
Biosynthesis of amino acids
Module
sce_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
YNR050C (LYS9)
00310 Lysine degradation
YNR050C (LYS9)
Enzymes [BR:
sce01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming)
YNR050C (LYS9)
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Motif
Pfam:
Sacchrp_dh_C
Sacchrp_dh_NADP
Shikimate_DH
NAD_binding_10
F420_oxidored
GFO_IDH_MocA
NAD_binding_3
3Beta_HSD
Epimerase
Motif
Other DBs
NCBI-GeneID:
855786
NCBI-ProteinID:
NP_014448
SGD:
S000005333
UniProt:
P38999
Structure
PDB
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Position
XIV:complement(714048..715388)
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AA seq
446 aa
AA seq
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MGKNVLLLGSGFVAQPVIDTLAANDDINVTVACRTLANAQALAKPSGSKAISLDVTDDSA
LDKVLADNDVVISLIPYTFHPNVVKSAIRTKTDVVTSSYISPALRELEPEIVKAGITVMN
EIGLDPGIDHLYAVKTIDEVHRAGGKLKSFLSYCGGLPAPEDSDNPLGYKFSWSSRGVLL
ALRNSAKYWKDGKIETVSSEDLMATAKPYFIYPGYAFVCYPNRDSTLFKDLYHIPEAETV
IRGTLRYQGFPEFVKALVDMGMLKDDANEIFSKPIAWNEALKQYLGAKSTSKEDLIASID
SKATWKDDEDRERILSGFAWLGLFSDAKITPRGNALDTLCARLEELMQYEDNERDMVVLQ
HKFGIEWADGTTETRTSTLVDYGKVGGYSSMAATVGYPVAIATKFVLDGTIKGPGLLAPY
SPEINDPIMKELKDKYGIYLKEKTVA
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagaacgttttgttgctaggatctggttttgttgcacaacctgttatcgacaca
ttggctgctaatgatgacatcaatgtcactgtcgcatgtagaacattagccaatgcgcaa
gcattggccaagccctctggatccaaggctatttcattggatgttaccgatgacagtgcc
ttagacaaagttctggctgataacgatgttgtcatctctttgattccatacaccttccat
ccaaatgtggtaaagagcgccatcagaacaaagaccgatgtcgtcacttcctcttacatc
tcacctgccttaagagaattggaaccagaaatcgtaaaggcaggtattacagttatgaac
gaaattgggttggatccaggtatcgaccacttgtatgcggtcaagactattgatgaagtt
cacagagctggtggtaagctaaagtcattcttgtcatactgtggtggtttaccagctcct
gaagactctgataatccattaggatacaaattttcatggtcctccagaggtgtgctactg
gctttaagaaactctgctaaatactggaaagacggaaagattgaaactgtttcttccgaa
gacttaatggccactgctaagccttacttcatctacccaggttatgcattcgtttgctac
ccaaatagagactctacccttttcaaggatctttatcatattccagaagccgaaacggtc
attagaggtactttgagatatcaaggtttcccagaatttgttaaggctttagttgacatg
ggtatgttgaaggatgatgctaacgaaatcttcagcaagccaattgcctggaacgaagca
ctaaaacaatatttaggtgccaagtctacttctaaagaagatttgattgcttccattgac
tcaaaggctacttggaaagatgatgaagatagagaaagaatcctttccgggtttgcttgg
ttaggcttgttctctgacgcaaagatcacaccaagaggtaatgctttagacactctatgt
gcacgtttagaagaactaatgcaatatgaagacaatgaaagagatatggttgtactacaa
cacaaattcggtattgaatgggctgatggaactaccgaaacaagaacatccactttagtt
gactatggtaaggttggtggttacagttctatggccgctactgttggttatccagttgcc
attgcaacgaaattcgtcttagatggtacaatcaagggaccaggcttactagcgccatac
tcaccagagattaatgatccaatcatgaaagaactaaaggacaagtacggcatctatcta
aaggaaaagacagtggcttaa
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