Entry
Symbol
OSGEP, KAE1, QRI7
Name
N6-L-threonylcarbamoyladenine synthase [EC:
2.3.1.234 ]
Reaction
R10648 L-threonylcarbamoyladenylate:adenine in tRNA N6-L-threonylcarbamoyltransferase
Disease
H01722 Galloway-Mowat syndrome
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis
K01409 OSGEP, KAE1, QRI7; N6-L-threonylcarbamoyladenine synthase
Enzymes [BR:ko01000 ]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.234 N6-L-threonylcarbamoyladenine synthase
K01409 OSGEP, KAE1, QRI7; N6-L-threonylcarbamoyladenine synthase
Transfer RNA biogenesis [BR:ko03016 ]
Eukaryotic type
tRNA modification factors
KEOPS/EKC complex
K01409 OSGEP, KAE1, QRI7; N6-L-threonylcarbamoyladenine synthase
Prokaryotic type
tRNA modification factors
KEOPS/EKC complex
K01409 OSGEP, KAE1, QRI7; N6-L-threonylcarbamoyladenine synthase
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
El Yacoubi B, Hatin I, Deutsch C, Kahveci T, Rousset JP, Iwata-Reuyl D, Murzin AG, de Crecy-Lagard V
Title
A role for the universal Kae1/Qri7/YgjD (COG0533) family in tRNA modification.
Journal
Sequence
Reference
Authors
Oberto J, Breuil N, Hecker A, Farina F, Brochier-Armanet C, Culetto E, Forterre P
Title
Qri7/OSGEPL, the mitochondrial version of the universal Kae1/YgjD protein, is essential for mitochondrial genome maintenance.
Journal
Sequence
Reference
Authors
Seki Y, Ikeda S, Kiyohara H, Ayabe H, Seki T, Matsui H
Title
Sequencing analysis of a putative human O-sialoglycoprotein endopeptidase gene (OSGEP) and analysis of a bidirectional promoter between the OSGEP and APEX genes.
Journal
Sequence
LinkDB
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