ORTHOLOGY: K03146
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Entry
K03146 KO
Symbol
THI4, THI1
Name
cysteine-dependent adenosine diphosphate thiazole synthase [EC:
2.4.2.60
]
Pathway
map00730
Thiamine metabolism
map01100
Metabolic pathways
map01240
Biosynthesis of cofactors
Module
M00897
Thiamine biosynthesis, plants, AIR (+ NAD+) => TMP/thiamine/TPP
M00898
Thiamine biosynthesis, pyridoxal-5P => TMP/thiamine/TPP
Reaction
R10685
NAD+:glycine ADP-D-ribosyltransferase (dehydroalanine-producing)
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00730 Thiamine metabolism
K03146 THI4, THI1; cysteine-dependent adenosine diphosphate thiazole synthase
Enzymes [BR:
ko01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.2 Pentosyltransferases
2.4.2.60 cysteine-dependent adenosine diphosphate thiazole synthase
K03146 THI4, THI1; cysteine-dependent adenosine diphosphate thiazole synthase
BRITE hierarchy
Other DBs
COG:
COG1635
Genes
ATH:
AT5G54770
(THI1)
ALY:
9300430
CRB:
17876896
CSAT:
104726000
104731059
104763460
EUS:
EUTSA_v10013978mg
BRP:
103844930
103851941
103857026
BNA:
106346007
106347311
106366413
106371241
106402237
106420919
125601255
BOE:
106318832
106327201
106335239
RSZ:
108836615
108837050
108844151
130501203
THJ:
104817652
CPAP:
110810965
CIT:
102626594
(thi)
102629135
CIC:
CICLE_v10008765mg
CICLE_v10015727mg
CICLE_v10024231mg
PVY:
116123427
MINC:
123202328
123225908
TCC:
18593644
18597097
GRA:
105769824
105773933
105780320
GHI:
107901923
107917921
107928645
107958248
107961959
121217764
GAB:
108453783
108482152
108486471
HSYR:
120126604
120147008
120160341
120179475
120189402
120197833
120209583
DZI:
111280819
111301627
111318798
EGR:
104450213
GMX:
100775614
100788953
100794288
547461
(SC-04)
547462
(SC-03)
GSJ:
114372051
114380540
114403613
114404912
114417056
PVU:
PHAVU_007G052900g
PHAVU_011G139100g
VRA:
106754377
106755182
VAR:
108325373
108339541
VUN:
114168645
114192234
VUM:
124843922
124843926
CCAJ:
109795024
109808173
APRC:
113872364
MTR:
11446281
25485243
TPRA:
123882686
CAM:
101491901
101507074
101511321
101512227
PSAT:
127097128
VVO:
131607286
131643448
LJA:
130718164
130743625
ADU:
107477997
107488645
AIP:
107630145
107643278
AHF:
112737808
112749911
112789941
112801227
LANG:
109331169
109332649
109348532
109351883
PCIN:
129286736
129298471
129298852
129315109
QSA:
O6P43_011880
O6P43_028946
O6P43_031212
FVE:
101298688
101299651
RCN:
112168087
112201505
112201899
PPER:
18780719
PMUM:
103342510
PDUL:
117623858
MDM:
103429668
103448581
MSYL:
126589528
126615015
PXB:
103948770
103967326
ZJU:
107407137
107420469
MNT:
21395127
CSAV:
115717421
CSV:
101211553
CMO:
103501605
BHJ:
120091480
CMAX:
111483293
111487533
CMOS:
111438464
111448035
CPEP:
111783834
111785935
111788519
RCU:
8280736
MEAN:
126670687
JCU:
105632894
HBR:
110647144
MESC:
110601845
110611614
POP:
7470933
7479083
7485534
PEU:
105108187
105130169
105134848
PALZ:
118035853
118047445
118059587
PNZ:
133698966
133703479
133703783
JRE:
108983682
108993518
109022013
CILL:
122277821
122282819
122289841
CAVE:
132170520
132173535
132176015
QSU:
111989411
112016278
QLO:
115956034
115956545
115972735
115988494
TWL:
119988758
119988861
VVI:
100260728
(THI1-1)
100265774
(THI1-2)
VRI:
117909200
117923467
SLY:
101257192
SPEN:
107025837
SOT:
102598996
SSTN:
125856795
SDUL:
129892560
CANN:
107856341
LBB:
132620419
NTA:
107797059
(ThiI)
107798781
NSY:
104224143
NTO:
104087540
NAU:
109232136
INI:
109167290
109187908
ITR:
116005701
116028414
SIND:
105167970
105175375
OEU:
111383503
111389379
EGT:
105948772
105962248
SSPL:
121740783
121742722
121743409
121757713
121775363
121800880
SMIL:
130985758
SHIS:
125188752
125202496
APAN:
127247867
127249630
HAN:
110890327
110912864
ECAD:
122591292
122611091
LSV:
111877285
111914386
CCAV:
112507403
112514948
DCR:
108199579
108204812
108211831
CSIN:
114275070
114297269
RVL:
131322345
131330436
AEW:
130751513
130751909
130754280
130789884
BVG:
104887771
104887775
SOE:
110795721
CQI:
110721030
110723750
ATRI:
130818300
MOF:
131145521
NNU:
104604883
MING:
122078253
122091022
TSS:
122640918
PSOM:
113279575
113284440
113287867
113288375
OSA:
4343443
OBR:
102709384
OGL:
127779938
BDI:
100841709
ATS:
109771029
TDC:
119281869
119330895
119338169
TAES:
123066078
123148177
123160697
123169109
TUA:
125525971
LPER:
127313554
127333271
LRD:
124669313
124679092
124689497
124695681
SBI:
8063504
8078187
ZMA:
542714
542715
MFLO:
136450051
136456136
136547283
136552755
136552773
SITA:
101752840
101774400
SVS:
117842602
117853273
PVIR:
120671321
120704075
PHAI:
112889419
PDA:
103716822
103721429
120107672
EGU:
105046898
105051965
MUS:
103975582
103991030
ZOF:
121967276
122021558
122025718
122052496
DCT:
110108175
PEQ:
110031149
AOF:
109827745
109834756
MSIN:
131221413
131239167
NCOL:
116249223
ATR:
18435056
SMO:
SELMODRAFT_163429
SELMODRAFT_271002
PPP:
112273035
112273481
112275550
112276032
112276579
CRE:
CHLRE_04g214150v5
VCN:
VOLCADRAFT_74899
VOLCADRAFT_74900
MNG:
MNEG_15292
MNEG_7985
CSL:
COCSUDRAFT_14398
CVR:
CHLNCDRAFT_22703
APRO:
F751_1708
SCE:
YGR144W
(THI4)
SEUB:
DI49_2107
SPAO:
SPAR_G03600
AGO:
AGOS_AAL137W
ERC:
Ecym_6012
KLA:
KLLA0_A00198g
KMX:
KLMA_40625
(THI4)
LTH:
KLTH0B03916g
VPO:
Kpol_1050p31
ZRO:
ZYRO0G11726g
CGR:
2891165
(GVI51_M01067)
NCS:
NCAS_0D01750
(NCAS0D01750)
NDI:
NDAI_0C02860
(NDAI0C02860)
TPF:
TPHA_0A04790
(TPHA0A04790)
TBL:
TBLA_0B09390
(TBLA0B09390)
TBLA_0H00760
(TBLA0H00760)
TGB:
HG536_0A04825
HG536_0F00230
TDL:
TDEL_0H00200
(TDEL0H00200)
KNG:
KNAG_0E03150
(KNAG0E03150)
ZMK:
HG535_0B00510
SLUD:
SCDLUD_003155
DHA:
DEHA2F16654g
PIC:
PICST_50942
PGU:
PGUG_04211
SPAA:
SPAPADRAFT_51398
LEL:
PVL30_003709
(THI4)
LBG:
92208508
(LODBEIA_P33120)
CAL:
CAALFM_C305130CA
(THI4)
CTP:
CTRG_02525
COT:
CORT_0C04770
CDU:
CD36_85100
CLU:
CLUG_04547
CLUS:
A9F13_11g02431
CAUR:
CJI96_0001634
PPA:
PAS_chr3_0648
PKZ:
C5L36_0C00170
BNN:
FOA43_001955
(STI35)
BBRX:
BRETT_001261
(THI4)
OPA:
HPODL_03615
YLI:
2905790
(YALI2_A00151g)
SLB:
AWJ20_4223
(THI4)
NCR:
NCU06110
NTE:
NEUTE1DRAFT95662
(NEUTE1DRAFT_95662)
SMP:
10802063
(SMAC4_06409)
PAN:
PODANSg1687
PBEL:
QC761_508470
(THI4)
PPSD:
QC762_508470
(THI4)
PPSP:
QC763_508470
(THI4)
PPSA:
QC764_508470
(THI4)
TTT:
THITE_2117402
MTM:
MYCTH_2315910
CTHR:
CTHT_0017160
MGR:
MGG_03098
PPEI:
PpBr36_09505
PGRI:
PgNI_10244
TMN:
UCRPA7_2510
SSCK:
SPSK_07738
FGR:
FGSG_02469
FPU:
FPSE_01936
FPOA:
FPOAC1_002586
(STI35)
FVN:
FVRRES_02879
FVR:
FVEG_09077
FOX:
FOXG_10428
NHE:
NECHADRAFT_61890
FFC:
NCS54_00810500
FKR:
NCS57_00853700
FMU:
J7337_005314
(STI35)
TRE:
TRIREDRAFT_68608
(thi4)
TRR:
M419DRAFT_89757
TATV:
25781467
(TrAtP1_003045)
TASP:
36616857
(TrAFT101_006760)
MAW:
19245497
(THI4_1)
MAJ:
MAA_05549
MBRN:
26238893
(sti35)
PCHM:
VFPPC_03188
CMT:
CCM_01639
AMUS:
LMH87_003448
PLJ:
28891457
(PLICBS_010469)
PTKZ:
JDV02_002359
(THI4)
VAL:
VDBG_03908
VDA:
VDAG_01137
CFJ:
CFIO01_04759
CLUP:
CLUP02_16278
CHIG:
CH63R_12560
CDET:
87942727
(CDEST_06224)
SAPO:
SAPIO_CDS2560
ELA:
UCREL1_6105
PFY:
PFICI_09188
SSL:
SS1G_09727
BFU:
BCIN_07g06010
(Bcthi4)
MBE:
MBM_01288
PSCO:
LY89DRAFT_683526
GLZ:
GLAREA_02091
ANI:
ANIA_03928
(thiF)
AFM:
AFUA_6G08360
ACT:
ACLA_082310
NFI:
NFIA_054010
AOR:
AO090003000090
ANG:
An11g01630
AFV:
AFLA_001605
ALUC:
AKAW2_80142S
(THI4)
ACHE:
ACHE_80625S
(THI4)
APUU:
APUU_40431S
(THI4)
PCS:
N7525_005441
PDP:
PDIP_32520
POU:
POX_d05776
TMF:
EYB26_005937
TRG:
TRUGW13939_06486
CIM:
CIMG_01115
CPW:
CPC735_052570
URE:
UREG_01058
ABE:
ARB_07940
TVE:
TRV_04098
PBL:
PAAG_01125
PBN:
PADG_03708
AJE:
HCAG_05915
BGH:
BDBG_03342
PNO:
SNOG_05965
PTE:
PTT_08482
PTRR:
6343353
(PtrM4_121390)
BZE:
COCCADRAFT_27023
BSC:
COCSADRAFT_38262
BOR:
COCMIDRAFT_30031
AALT:
CC77DRAFT_1021441
ARAB:
EKO05_0000764
ZTR:
MYCGRDRAFT_44262
PFJ:
MYCFIDRAFT_211863
FFU:
CLAFUR5_09695
CBET:
CB0940_10496
BCOM:
BAUCODRAFT_62660
NPA:
UCRNP2_7340
SPO:
2540526
(thi2)
SOM:
SOMG_00517
(thi2)
TVS:
TRAVEDRAFT_71517
DSQ:
DICSQDRAFT_134894
PCO:
PHACADRAFT_177254
SHS:
STEHIDRAFT_111603
HIR:
HETIRDRAFT_440039
PSQ:
PUNSTDRAFT_42416
ADL:
AURDEDRAFT_139075
FME:
FOMMEDRAFT_23696
GTR:
GLOTRDRAFT_77212
RSX:
RhiXN_04607
CCI:
CC1G_04976
ABP:
AGABI1DRAFT40074
(AGABI1DRAFT_40074)
ABV:
AGABI2DRAFT72787
(AGABI2DRAFT_72787)
PCUB:
JR316_0006998
MRR:
Moror_11852
MORE:
E1B28_012388
SCM:
SCHCO_02490971
(SCHCODRAFT_02490971)
CPUT:
CONPUDRAFT_104209
SLA:
SERLADRAFT_470126
WSE:
WALSEDRAFT_32181
(CYPBP37)
WIC:
J056_001533
UMA:
UMAG_11400
PFP:
PFL1_06351
SGRA:
EX895_003350
MGL:
MGL_1314
MSYM:
MSY001_3139
PGR:
PGTG_01304
PTRC:
PtA15_7A55
PSTR:
Pst134EA_013047
MLR:
MELLADRAFT_53832
SPAR:
SPRG_04526
GTT:
GUITHDRAFT_93981
» show all
Taxonomy
UniProt
Reference
PMID:
22031445
Authors
Chatterjee A, Abeydeera ND, Bale S, Pai PJ, Dorrestein PC, Russell DH, Ealick SE, Begley TP
Title
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.
Journal
Nature 478:542-6 (2011)
DOI:
10.1038/nature10503
Sequence
[sce:
YGR144W
]
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integrated database retrieval system