KEGG   ORTHOLOGY: K03847
Entry
K03847                      KO                                     
Symbol
ALG12
Name
alpha-1,6-mannosyltransferase [EC:2.4.1.260]
Pathway
map00510  N-Glycan biosynthesis
map00513  Various types of N-glycan biosynthesis
map01100  Metabolic pathways
Module
M00055  N-glycan precursor biosynthesis
Disease
H00118  Congenital disorders of glycosylation type I
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K03847  ALG12; alpha-1,6-mannosyltransferase
   00513 Various types of N-glycan biosynthesis
    K03847  ALG12; alpha-1,6-mannosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K03847  ALG12; alpha-1,6-mannosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.260  dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
     K03847  ALG12; alpha-1,6-mannosyltransferase
Glycosyltransferases [BR:ko01003]
 N-Glycan biosynthesis
  Dol-linked oligosaccharide
   K03847  ALG12; alpha-1,6-mannosyltransferase
Other DBs
RN: R06260
GO: 0000009
CAZy: GT22
Genes
HSA: 79087(ALG12)
PTR: 470247(ALG12)
PPS: 100977641(ALG12)
GGO: 101126908(ALG12)
PON: 100431368(ALG12)
NLE: 100588258(ALG12)
MCC: 715172(ALG12)
MCF: 102117563(ALG12)
CSAB: 103223543(ALG12)
CATY: 105586894(ALG12)
PANU: 101025888(ALG12)
TGE: 112633486(ALG12)
RRO: 104670360(ALG12)
RBB: 108516534(ALG12)
TFN: 117096285(ALG12)
PTEH: 111549098(ALG12)
CJC: 100392255(ALG12)
SBQ: 101036432(ALG12)
CSYR: 103255319(ALG12)
MMUR: 105885030(ALG12)
LCAT: 123640778(ALG12)
OGA: 100966838(ALG12)
MMU: 223774(Alg12)
MCAL: 110310083(Alg12)
MPAH: 110334975(Alg12)
RNO: 315212(Alg12)
MCOC: 116077624(Alg12)
MUN: 110549675(Alg12)
CGE: 100770096(Alg12)
MAUA: 101830842(Alg12)
PLEU: 114699216(Alg12)
MORG: 121461007(Alg12)
AAMP: 119822329(Alg12)
NGI: 103735462(Alg12)
HGL: 101715432(Alg12)
CPOC: 100722302(Alg12)
CCAN: 109697709(Alg12)
DORD: 105992753(Alg12)
DSP: 122123645(Alg12)
NCAR: 124982111
OCU: 100346344(ALG12)
OPI: 101529961(ALG12)
TUP: 102492059(ALG12)
CFA: 481196(ALG12)
VVP: 112935830(ALG12)
VLG: 121491169(ALG12) 121497486
AML: 100477708(ALG12)
UMR: 103674123(ALG12)
UAH: 113241629(ALG12)
UAR: 123803790(ALG12)
ELK: 111157563
LLV: 125106489
MPUF: 101676994(ALG12)
ORO: 101363058(ALG12)
EJU: 114218378(ALG12)
ZCA: 113921767(ALG12)
MLX: 117997755(ALG12) 118012103
FCA: 101099567(ALG12)
PYU: 121040139(ALG12)
PBG: 122472969(ALG12)
PPAD: 109265747(ALG12)
AJU: 106987628(ALG12)
HHV: 120233734(ALG12)
BTA: 100125314(ALG12)
BOM: 102281651(ALG12)
BBUB: 102403805(ALG12)
CHX: 102181760(ALG12)
OAS: 101112896(ALG12)
ODA: 120857818(ALG12)
CCAD: 122423526(ALG12)
SSC: 100520494(ALG12)
CFR: 102524349(ALG12)
CBAI: 105070796(ALG12)
CDK: 105090366(ALG12)
VPC: 102526385(ALG12)
BACU: 103004635(ALG12)
LVE: 103079764(ALG12)
OOR: 101285549(ALG12)
DLE: 111186266(ALG12)
PCAD: 102975935(ALG12)
PSIU: 116760259(ALG12)
ECB: 100146652(ALG12)
EPZ: 103565594(ALG12)
EAI: 106845994(ALG12)
MYB: 102251651(ALG12)
MYD: 102767133(ALG12)
MMYO: 118657377(ALG12)
MLF: 102434071(ALG12)
MNA: 107536069(ALG12)
PKL: 118714726(ALG12)
HAI: 109396645(ALG12)
DRO: 112321642(ALG12)
SHON: 118989148(ALG12)
AJM: 119060267(ALG12)
PDIC: 114513325(ALG12)
PHAS: 123816086(ALG12)
MMF: 118641182(ALG12)
RFQ: 117028108(ALG12)
PALE: 102883747(ALG12)
PGIG: 120602849(ALG12)
PVP: 105303067(ALG12)
RAY: 107500277(ALG12)
MJV: 108401703(ALG12)
TOD: 119247142(ALG12)
SARA: 101542405(ALG12)
LAV: 100661791(ALG12)
TMU: 101345042
DNM: 101417420(ALG12)
GAS: 123248656(ALG12)
SHR: 100920134(ALG12)
PCW: 110205944(ALG12)
OAA: 100073873(ALG12)
GGA: 417733(ALG12)
PCOC: 116243510(ALG12)
MGP: 100538714(ALG12)
CJO: 107308331(ALG12)
NMEL: 110392463(ALG12)
APLA: 101790290(ALG12)
ACYG: 106040489(ALG12)
AFUL: 116487132(ALG12)
TGU: 100228059(ALG12)
LSR: 110484518(ALG12)
SCAN: 103813496(ALG12)
PMOA: 120510722(ALG12)
OTC: 121336391(ALG12)
PRUF: 121365725(ALG12)
GFR: 102041702(ALG12)
FAB: 101811748(ALG12)
PHI: 102108073(ALG12)
PMAJ: 107204336(ALG12)
CCAE: 111923041(ALG12)
CCW: 104686842(ALG12)
ETL: 114060230(ALG12)
ZAB: 102060913(ALG12)
FPG: 101921937(ALG12)
FCH: 102049527(ALG12)
CLV: 102086330(ALG12)
EGZ: 104134412(ALG12)
NNI: 104010710(ALG12)
PLET: 104614394(ALG12)
ACUN: 113491358(ALG12)
TALA: 104361818(ALG12)
PADL: 103912493(ALG12)
ACHC: 115342306(ALG12)
AAM: 106495380(ALG12)
AROW: 112968148(ALG12)
NPD: 112959725(ALG12)
DNE: 112990919(ALG12)
ASN: 102370274(ALG12)
AMJ: 102563831(ALG12)
CPOO: 109315679(ALG12)
GGN: 109292099(ALG12)
PSS: 102447329(ALG12)
CMY: 102931282(ALG12)
CPIC: 101946366(ALG12)
TST: 117875810(ALG12)
CABI: 116822544(ALG12)
MRV: 120390892(ALG12)
ACS: 100560474(alg12)
PVT: 110076228(ALG12)
SUND: 121930865(ALG12)
PBI: 103051026(ALG12)
PMUR: 107289329(ALG12)
TSR: 106553630(ALG12)
PGUT: 117667488(ALG12)
VKO: 123020080(ALG12)
PMUA: 114605130(ALG12)
ZVI: 118091452(ALG12) 118091486
GJA: 107112025(ALG12)
STOW: 125434375(ALG12)
XLA: 108711164(alg12.L)
XTR: 548874(alg12)
NPR: 108796727(ALG12)
RTEM: 120931812(ALG12)
BBUF: 120982181(ALG12)
BGAR: 122927909(ALG12)
DRE: 569494(alg12)
SRX: 107730685(alg12)
SANH: 107699370(alg12)
SGH: 107601012(alg12)
CCAR: 109055011 109088012
CAUA: 113062033(alg12)
PPRM: 120470641(alg12)
MAMB: 125244758(alg12)
IPU: 108279802(alg12)
PHYP: 113532285(alg12)
SMEO: 124400835(alg12)
TFD: 113645776(alg12)
AMEX: 103044448(alg12)
EEE: 113573577(alg12)
TRU: 101076670(alg12)
LCO: 104926575(alg12)
NCC: 104953716(alg12)
CGOB: 115028430(alg12)
ELY: 117249287(alg12)
PLEP: 121961146(alg12)
SLUC: 116039834(alg12)
ECRA: 117939015(alg12)
GAT: 120817156(alg12)
PPUG: 119210230(alg12)
MSAM: 119918384(alg12)
CUD: 121505529(alg12)
ALAT: 119032691(alg12)
MZE: 101476903(alg12)
ONL: 100702718(alg12)
OAU: 116334940(alg12)
OLA: 101171875(alg12)
OML: 112153250(alg12)
XMA: 102222592(alg12)
XCO: 114160906(alg12)
XHE: 116736399(alg12)
PRET: 108165888(alg12)
PLAI: 106948934(alg12)
PMEI: 106916605(alg12)
GAF: 122826702(alg12)
CVG: 107094556(alg12)
CTUL: 119776230(alg12)
GMU: 124883390(alg12)
NFU: 107383916(alg12)
KMR: 108240986(alg12)
ALIM: 106521807(alg12)
NWH: 119428033(alg12)
AOCE: 111565703(alg12)
CSEM: 103382918(alg12)
POV: 109632793(alg12)
SSEN: 122766437(alg12)
HHIP: 117757271(alg12)
HSP: 118101401(alg12)
LCF: 108899853(alg12)
SDU: 111224930(alg12)
SLAL: 111651992(alg12)
XGL: 120798037(alg12)
HCQ: 109523664(alg12)
BPEC: 110161826(alg12)
MALB: 109960949(alg12)
BSPL: 114861967(alg12)
SASA: 100195409(alg12) 106609155
OTW: 112216768(alg12)
OMY: 110490157(alg12)
OGO: 123994733(alg12)
ONE: 115106856(alg12)
SALP: 111951472(alg12)
SNH: 120031914(alg12)
ELS: 105020252(alg12)
SFM: 108931614(alg12)
PKI: 111853381(alg12)
AANG: 118219378(alg12)
LOC: 102691088(alg12)
PSPA: 121319749(alg12)
ARUT: 117415153 117419504 117968879
CMK: 103177032(alg12)
RTP: 109915320(alg12)
BFO: 118415924
BBEL: 109472143
CIN: 100177471
SCLV: 120335788
SPU: 591306
APLC: 110974150
SKO: 100374699
DME: Dmel_CG8412(CG8412)
DER: 6552279
DSE: 6607047
DSI: Dsimw501_GD18643(Dsim_GD18643)
DYA: Dyak_GE25981
DAN: 6505681
DSR: 110191756
DPO: Dpse_GA21058
DPE: 6587997
DMN: 108155365
DWI: 6646959
DGR: 6568493
DMO: Dmoj_GI22746
DAZ: 108618404
DNV: 108648979
DHE: 111602790
DVI: 6629887
CCAT: 101449681
BOD: 106617807
MDE: 101900007
SCAC: 106093557
LCQ: 111690971
LSQ: 119601700
HIS: 119652389
AGA: AgaP_AGAP000102
ACOZ: 120949342
AARA: 120905777
ASTE: 118505208
AAG: 5564018
AALB: 109428475 115260009
CQU: CpipJ_CPIJ009375
CPII: 120432219
CNS: 116338790
BCOO: 119069488
AME: 724431
ACER: 108001285
ALAB: 122720236
BIM: 105680192
BVK: 117237785
BVAN: 117166080
BTER: 105665616
BPYO: 122576964
CCAL: 108623949
OBB: 114876027
MGEN: 117228138
NMEA: 116426687
CGIG: 122398797
SOC: 105198677
MPHA: 105838989
AEC: 105151528
ACEP: 105625286
PBAR: 105425633
VEM: 105560245
HST: 105191684
DQU: 106743760
CFO: 105250907
FEX: 115243518
LHU: 105677564
PGC: 109854174
OBO: 105286193
PCF: 106788943
PFUC: 122516803
VPS: 122631077
NVI: 100120808
CSOL: 105367648
TPRE: 106651852
MDL: 103572453
CGLO: 123275086
DAM: 107046240
CCIN: 107263490
TCA: 660266
DPA: 109534052
SOY: 115890667
ATD: 109601432
CSET: 123308684
AGB: 108909635
NVL: 108569886
APLN: 108740479
PPYR: 116170268
OTU: 111415243
BMOR: 101745504
BMAN: 114250897
MSEX: 115450201
DPL: KGM_214579
BANY: 112044345
PMAC: 106721445
PPOT: 106104341
PXU: 106120331
PRAP: 110993073
ZCE: 119828467 119828764
HAW: 110382926
TNL: 113498899
SLIU: 111350370
OFU: 114360779
PXY: 105392967
API: 100160697
AGS: 114128596
RMD: 113556719
BTAB: 109030158
DCI: 103519096 108252388
CLEC: 106666615
HHAL: 106685794
NLU: 111044467
PHU: Phum_PHUM333940
ZNE: 110831686
FCD: 110842961
DPX: DAPPUDRAFT_307223 DAPPUDRAFT_340335
DMK: 116929215
PVM: 113819574 113830310
PJA: 122258463
PCHN: 125033412
PCLA: 123746266
PTRU: 123510247
HAZT: 108665558
LSM: 121121244
PPOI: 119093282
ISC: IscW_ISCW010680
DSV: 119460564
RSAN: 119397066
RMP: 119175072
VDE: 111243282
VJA: 111265944
TUT: 107359154
DPTE: 113795019
DFR: 124490814
CSCU: 111614632
PTEP: 107438060 122268870
SDM: 118192007
CEL: CELE_ZC513.5(algn-12)
CBR: CBG_11382
BMY: BM_BM7406(Bm7406)
LOA: LOAG_16479
NAI: NECAME_10496
TSP: Tsp_15122
HRO: HELRODRAFT_70039
LGI: LOTGIDRAFT_228830
PCAN: 112567001
BGT: 106074820
GAE: 121390318
HRF: 124136036
HRJ: 124283281
CRG: 105322567
MYI: 110454805
PMAX: 117331552
MMER: 123529376
OBI: 106867594
OSN: 115212963
LAK: 106178263
SMM: Smp_161590
OVI: T265_07001
EGL: EGR_00931
NVE: 5521096
EPA: 110245274
ATEN: 116306863
ADF: 107341875
AMIL: 114946922
PDAM: 113684862
SPIS: 111339781
DGT: 114521801
XEN: 124434036
HMG: 100214068
TAD: TRIADDRAFT_28195
AQU: 100640861
ATH: AT1G02145(ALG12)
ALY: 9328085
CRB: 17897192
CSAT: 104758180 104773533 104773734
EUS: EUTSA_v10007459mg
BRP: 103843832 103844697
BNA: 106370825 106400825 106434177
BOE: 106294422 106308420
RSZ: 108806148 108857290
THJ: 104814061
CPAP: 110816214
CIT: 102622888
CIC: CICLE_v10019843mg
PVY: 116135967
MINC: 123215301
TCC: 18614505
GRA: 105791709
GHI: 107900803 107929688
GAB: 108470165
DZI: 111313726
EGR: 104444420
GMX: 100776070 100786127
GSJ: 114406490 114418815
PVU: PHAVU_010G045600g
VRA: 106774197
VAR: 108347728
VUN: 114167535
CCAJ: 109818826
APRC: 113849359
MTR: MTR_8g007345
CAM: 101509278
LJA: Lj0g3v0165139.2(Lj0g3v0165139.2) Lj3g3v0594260.1(Lj3g3v0594260.1) Lj3g3v0594260.2(Lj3g3v0594260.2)
ADU: 107464448
AIP: 107618752
AHF: 112710211 112776335
LANG: 109352550
FVE: 101300391
RCN: 112181879
PPER: 109947168
PMUM: 103331526
PAVI: 110745699
PDUL: 117619824
MDM: 103438967
PXB: 103964190
ZJU: 107421766
MNT: 21391423
CSV: 101222209
CMO: 103498998
BHJ: 120067141
MCHA: 111022781
CMAX: 111499003
CMOS: 111460074
CPEP: 111807199
RCU: 8263298
JCU: 105643234
HBR: 110635799
MESC: 110615915
POP: 7483803
PEU: 105120738
PALZ: 118042166
JRE: 109016718
QSU: 112001704 112013381
QLO: 115987320
TWL: 119984708
VVI: 100253051
VRI: 117932336
SLY: 101253423
SPEN: 107028308
SOT: 102579208
CANN: 107844599
NTA: 107790560 107800663
NSY: 104216946
NTO: 104098178
NAU: 109224565
INI: 109155587
ITR: 115997343
SIND: 105169914
OEU: 111383370
EGT: 105954823
SSPL: 121775114 121802383 121808053
HAN: 110922314
ECAD: 122595710
LSV: 111885666
CCAV: 112522500
DCR: 108202471
CSIN: 114276460
BVG: 104905254
SOE: 110803939
CQI: 110720492 110721548
NNU: 104589452
MING: 122084134
TSS: 122665382
PSOM: 113284616 113343855
NCOL: 116252677
OSA: 4336560
DOSA: Os04t0544900-01(Os04g0544900)
OBR: 102708889
BDI: 100830072
ATS: 109740842
TDC: 119355961 119365096
TAES: 123046208 123054085 123189971
TUA: 125531250
SBI: 8055942
ZMA: 100282442
SITA: 101755068
SVS: 117864492
PVIR: 120642645 120682558
PHAI: 112901344
PDA: 103704603
EGU: 105053932
MUS: 103970072
DCT: 110107771
PEQ: 110020637
AOF: 109839065
ATR: 18429228
SMO: SELMODRAFT_91475(GT22A3)
PPP: 112295252
CSL: COCSUDRAFT_29611
CVR: CHLNCDRAFT_8393
APRO: F751_2283
OLU: OSTLU_43663
OTA: OT_ostta14g02510
BPG: Bathy13g00280
MIS: MICPUN_63738
MPP: MICPUCDRAFT_22710
GSL: Gasu_59850
CCP: CHC_T00009193001
SCE: YNR030W(ALG12)
SEUB: DI49_4762
SPAO: SPAR_N03310
AGO: AGOS_AAR043C
ERC: Ecym_2496
KLA: KLLA0_C08591g
KMX: KLMA_70199(ALG12)
LTH: KLTH0A06710g
VPO: Kpol_1028p42
ZRO: ZYRO0D08250g
CGR: CAGL0M10769g
NCS: NCAS_0A05360(NCAS0A05360)
NDI: NDAI_0K02210(NDAI0K02210)
TPF: TPHA_0M01820(TPHA0M01820)
TBL: TBLA_0F04110(TBLA0F04110)
TDL: TDEL_0A07530(TDEL0A07530)
TGB: HG536_0A09110
KAF: KAFR_0C04580(KAFR0C04580)
KNG: KNAG_0D00400(KNAG0D00400)
ZMK: HG535_0A07420
PPA: PAS_chr4_0544
DHA: DEHA2C17270g
PIC: PICST_31100(ECM39)
PGU: PGUG_03898
SPAA: SPAPADRAFT_63472
LEL: LELG_05213
CAL: CAALFM_C702970WA(ECM39)
CTP: CTRG_05215
COT: CORT_0G04380
CDU: CD36_72630
YLI: YALI0C02475g
CLU: CLUG_04302
CLUS: A9F13_04g02123
CAUR: CJI97_000738
SLB: AWJ20_3629(ALG12)
PKZ: C5L36_0E01690
BNN: FOA43_004766
BBRX: BRETT_001636
SLUD: SCDLUD_003737
NCR: NCU07472
NTE: NEUTE1DRAFT88888(NEUTE1DRAFT_88888)
SMP: SMAC_05174
PAN: PODANSg09956
TTT: THITE_21903
MTM: MYCTH_2295836
CTHR: CTHT_0053460
MGR: MGG_09909
PPEI: PpBr36_07683
TMN: UCRPA7_6503
SSCK: SPSK_08732
FGR: FGSG_01233
FPU: FPSE_01776
FVR: FVEG_01362
FOX: FOXG_00155
NHE: NECHADRAFT_105807
TRE: TRIREDRAFT_63828
TRR: M419DRAFT_130862
MAW: MAC_00572
MAJ: MAA_07235
CMT: CCM_06927
PLJ: VFPFJ_03373
VDA: VDAG_04507
CFJ: CFIO01_04924
CHIG: CH63R_00467
SAPO: SAPIO_CDS0782
ELA: UCREL1_7790
PFY: PFICI_01052
SSL: SS1G_10012
BFU: BCIN_07g04680
MBE: MBM_02529
PSCO: LY89DRAFT_604257
GLZ: GLAREA_00829
ANI: AN3588.2
AFM: AFUA_4G12900
ACT: ACLA_051860
NFI: NFIA_103440
AOR: AO090009000318
ANG: ANI_1_1126014(An01g08460)
AFV: AFLA_011040
ALUC: AKAW2_20899A(ALG12)
ACHE: ACHE_10334A(ALG12)
APUU: APUU_60284A(ALG12)
PCS: Pc22g02840
PDP: PDIP_44640
TMF: PMAA_039770
TRG: TRUGW13939_02644
CIM: CIMG_00617
CPW: CPC735_056390
URE: UREG_00622
PBL: PAAG_07032
PBN: PADG_01561
ABE: ARB_00142
TVE: TRV_01650
BGH: BDBG_16518
PNO: SNOG_04448
PTE: PTT_15141
BZE: COCCADRAFT_2870
BSC: COCSADRAFT_191517
BOR: COCMIDRAFT_98235
AALT: CC77DRAFT_933602
ZTR: MYCGRDRAFT_109480
PFJ: MYCFIDRAFT_34652
FFU: CLAFUR5_08542
BCOM: BAUCODRAFT_35286
NPA: UCRNP2_3478
SPO: SPBC1734.12c(alg12)
CNE: CNC03430
CNB: CNBC3790
CNG: CNAG_02715 CNAG_07527
CGI: CGB_C5280C
TMS: TREMEDRAFT_41756
TASA: A1Q1_05444
TVS: TRAVEDRAFT_126346
PCO: PHACADRAFT_180449 PHACADRAFT_214615
SHS: STEHIDRAFT_165833 STEHIDRAFT_73504
HIR: HETIRDRAFT_165790
PSQ: PUNSTDRAFT_120292
ADL: AURDEDRAFT_143051
FME: FOMMEDRAFT_131787
GTR: GLOTRDRAFT_79634
LBC: LACBIDRAFT_302539(ALG12)
MRR: Moror_3413
MORE: E1B28_010872
CCI: CC1G_11662
SCM: SCHCODRAFT_104684
ABP: AGABI1DRAFT75475(AGABI1DRAFT_75475)
ABV: AGABI2DRAFT184199(AGABI2DRAFT_184199)
CPUT: CONPUDRAFT_151427
SLA: SERLADRAFT_467450
WSE: WALSEDRAFT_68580
WIC: J056_001199
UMA: UMAG_11341
PFP: PFL1_03512
MGL: MGL_2261
MRT: MRET_0251
MSYM: MSY001_1982(ALG12)
PGR: PGTG_03644
MLR: MELLADRAFT_40792
MBR: MONBRDRAFT_31470
SRE: PTSG_11395
DDI: DDB_G0267884(alg12)
DPP: DICPUDRAFT_80121
DFA: DFA_08503(alg12)
PTI: PHATRDRAFT_44425
FCY: FRACYDRAFT_247580
TPS: THAPSDRAFT_262459
PIF: PITG_10838
PSOJ: PHYSODRAFT_469873
SPAR: SPRG_11694 SPRG_16521
EHX: EMIHUDRAFT_454648
GTT: GUITHDRAFT_65500
TBR: Tb927.2.4720
TBG: TbgDal_II2750
TCR: 509317.50 511621.60
NGR: NAEGRDRAFT_29294
 » show all
Reference
PMID:10336995
  Authors
Burda P, Jakob CA, Beinhauer J, Hegemann JH, Aebi M
  Title
Ordered assembly of the asymmetrically branched lipid-linked oligosaccharide in the endoplasmic reticulum is ensured by the substrate specificity of the individual glycosyltransferases.
  Journal
Glycobiology 9:617-25 (1999)
DOI:10.1093/glycob/9.6.617
  Sequence
[sce:YNR030W]
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