KEGG   ORTHOLOGY: K03898
Entry
K03898                      KO                                     
Symbol
KNG, BK
Name
kininogen
Pathway
map04022  cGMP-PKG signaling pathway
map04071  Sphingolipid signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04610  Complement and coagulation cascades
map04750  Inflammatory mediator regulation of TRP channels
map04810  Regulation of actin cytoskeleton
map05142  Chagas disease
map05143  African trypanosomiasis
map05200  Pathways in cancer
Disease
H01006  Hereditary angioedema
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K03898  KNG, BK; kininogen
   04022 cGMP-PKG signaling pathway
    K03898  KNG, BK; kininogen
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K03898  KNG, BK; kininogen
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K03898  KNG, BK; kininogen
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03898  KNG, BK; kininogen
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K03898  KNG, BK; kininogen
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K03898  KNG, BK; kininogen
  09174 Infectious disease: parasitic
   05142 Chagas disease
    K03898  KNG, BK; kininogen
   05143 African trypanosomiasis
    K03898  KNG, BK; kininogen
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03898  KNG, BK; kininogen
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K03898  KNG, BK; kininogen
   04052 Cytokines and neuropeptides
    K03898  KNG, BK; kininogen
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I25: cystatin family
   K03898  KNG, BK; kininogen
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   K03898  KNG, BK; kininogen
  Exosomal proteins of other cancer cells
   K03898  KNG, BK; kininogen
Cytokines and neuropeptides [BR:ko04052]
 Neuropeptides
  Neuropeptides (GPCR binding)
   K03898  KNG, BK; kininogen
Other DBs
GO: 0004869
Genes
HSA: 3827(KNG1)
PTR: 460916(KNG1)
PPS: 100995206(KNG1)
GGO: 101138554(KNG1)
PON: 100432100(KNG1)
PPYG: 129032584(KNG1)
NLE: 100597381(KNG1)
HMH: 116479942(KNG1)
SSYN: 134732976(KNG1)
MCC: 707466(KNG1)
MCF: 102124671(KNG1)
MTHB: 126946400
MNI: 105470991(KNG1)
CSAB: 103241872(KNG1)
CATY: 105575221(KNG1)
PANU: 101012078(KNG1)
TGE: 112618101(KNG1)
MLEU: 105527869(KNG1)
RRO: 104682884(KNG1)
RBB: 108530457(KNG1)
TFN: 117084346(KNG1)
PTEH: 111544258(KNG1)
CANG: 105525808(KNG1)
CJC: 100405422(KNG1)
SBQ: 101030410(KNG1)
CIMI: 108311051(KNG1)
ANAN: 105729889(KNG1)
CSYR: 103258701(KNG1)
MMUR: 105885036(KNG1)
LCAT: 123630368(KNG1)
PCOQ: 105807671(KNG1)
OGA: 100952099(KNG1)
MMU: 16644(Kng1) 385643(Kng2)
MCAL: 110311183
MPAH: 110329894(Kng1) 110330025
RNO: 24903(Kng2) 25087(Kng2l1) 288001(Kng1)
MCOC: 116086252(Kng1) 116086253
ANU: 117717902(Kng1) 117718001
MUN: 110548116(Kng1)
CGE: 100764285(Kng1)
MAUA: 101824613(Kng1)
PROB: 127226817 127227002(Kng1)
PLEU: 114697109(Kng1)
MORG: 121464990 121465076(Kng1)
MFOT: 126504268 126504348
AAMP: 119824630 119824681 119824900
NGI: 103726185(Kng1)
HGL: 101721023(Kng1)
CPOC: 100735583(Kng1)
CCAN: 109678128
DORD: 105999708(Kng1)
DSP: 122098556(Kng1)
PLOP: 125351899(Kng1)
NCAR: 124993322
MMMA: 107154354(Kng1)
OCU: 100101602
OPI: 101534400(KNG1)
TUP: 102501029(KNG1)
GVR: 103598676(KNG1)
CFA: 478666(KNG1)
CLUD: 112662728(KNG1)
VVP: 112926295(KNG1)
VLG: 121477507(KNG1)
NPO: 129498954(KNG1)
AML: 100482228(KNG1)
UMR: 103676052(KNG1)
UAH: 113253918(KNG1)
UAR: 123801268(KNG1)
ELK: 111148821
LLV: 125101886
MPUF: 101670490(KNG1)
MNP: 132011953(KNG1)
MLK: 131824751(KNG1)
NVS: 122908785(KNG1)
ORO: 101375897(KNG1)
EJU: 114207026(KNG1)
ZCA: 113918484(KNG1)
MLX: 118000407(KNG1)
NSU: 110582714(KNG1)
LWW: 102735300(KNG1)
FCA: 101099143(KNG1)
PYU: 121034124(KNG1)
PCOO: 112849750(KNG1)
PBG: 122491631(KNG1)
PVIV: 125175753(KNG1)
LRUF: 124526765
PTG: 102960528(KNG1)
PPAD: 109275271
PUC: 125921824
AJU: 106968026
HHV: 120238113(KNG1)
BTA: 280833(KNG1)
BOM: 102270660(KNG1)
BIU: 109562726
BBUB: 102408091(KNG1)
BBIS: 104998627(KNG1)
CHX: 102174978(KNG1)
OAS: 101112781(KNG1)
BTAX: 128054455(KNG1)
ODA: 120872422(KNG1)
CCAD: 122444813(KNG1)
MBEZ: 129550727(KNG1)
SSC: 396568(KNG1)
CFR: 102511736(KNG1)
CBAI: 105072331(KNG1)
CDK: 105085847(KNG1)
VPC: 102529551(KNG1)
BACU: 103014171(KNG1)
BMUS: 118894349(KNG1)
LVE: 103076963(KNG1)
OOR: 101283768(KNG1)
DLE: 111172863(KNG1)
PCAD: 102987999(KNG1)
PSIU: 116753679(KNG1)
NASI: 112415692(KNG1)
ECB: 100068133(KNG1)
EPZ: 103540309(KNG1)
EAI: 106832539(KNG1)
MYB: 102242693(KNG1) 102246781 102247581
MYD: 102761588 102761876(KNG1)
MMYO: 118675748 118675750 118676365(KNG1)
MLF: 102431641(KNG1) 102432377 102432691 102433011 102441373 102442936 111825105
MDT: 132230216 132230217 132230218 132230219 132230220
PKL: 118724652(KNG1) 118724654 118724655
EFUS: 103295193 103295196 103300685 114226691
MNA: 107527424(KNG1)
DRO: 112305173(KNG1) 112305188
SHON: 118983148(KNG1)
AJM: 119047624
PDIC: 114490760 114490814
PHAS: 123827047 123827144
MMF: 118616939(KNG1)
PPAM: 129079861 129079863
HAI: 109371464(KNG1)
RFQ: 117036298 117036324(KNG1)
PALE: 102885643(KNG1)
PGIG: 120592907(KNG1)
PVP: 105306731(KNG1)
RAY: 107505885(KNG1)
MJV: 108385678(KNG1)
TOD: 119256781 119256782 119256784 119258076 119258080 119258084(KNG1)
SARA: 101541147(KNG1)
SETR: 126011862(KNG1)
LAV: 100655555(KNG1)
TMU: 101352995
ETF: 101650277(KNG1)
DNM: 101447220(KNG1)
MDO: 103103071(KNG1)
GAS: 123242029(KNG1)
SHR: 100931404(KNG1)
AFZ: 127558388
PCW: 110210135(KNG1)
TVP: 118845718(KNG1)
OAA: 100680799(KNG1)
GGA: 424957(KNG1)
PCOC: 116235415(KNG1)
MGP: 104912678(KNG1)
CJO: 107318178(KNG1)
TPAI: 128081843(KNG1)
LMUT: 125697364(KNG1)
NMEL: 110397811(KNG1)
APLA: 101790881(KNG1)
ACYG: 106032051(KNG1)
CATA: 118253176(KNG1)
AFUL: 116492399(KNG1)
TGU: 101233490(KNG1)
LSR: 110477726(KNG1)
SCAN: 103815327(KNG1)
PMOA: 120504324(KNG1)
OTC: 121336626(KNG1)
PRUF: 121353759(KNG1)
GFR: 102032656(KNG1)
FAB: 101808930(KNG1)
OMA: 130256751(KNG1)
PHI: 102110516(KNG1)
CCAE: 111933378(KNG1)
CCW: 104687993(KNG1)
CBRC: 103625182(KNG1)
ETL: 114060796(KNG1)
ZAB: 102060613(KNG1)
ZLE: 135451815(KNG1)
ACHL: 103807859(KNG1)
SVG: 106850330(KNG1)
MMEA: 130574101(KNG1)
HRT: 120757225(KNG1)
SATI: 136365401(KNG1)
FPG: 101918337(KNG1)
FCH: 102051534(KNG1)
CCRI: 104162556(KNG1)
NNT: 104402701(KNG1)
SHAB: 115611526(KNG1)
ACUN: 113483395(KNG1)
TALA: 104360455(KNG1)
ACHC: 115346711(KNG1)
HALD: 104320734
HLE: 104835129(KNG1)
AGEN: 126039107
GCL: 127020263
CSTI: 104552139(KNG1)
LDI: 104346390(KNG1)
MNB: 103770977(KNG1)
DPUB: 104303028(KNG1)
AVIT: 104272680(KNG1)
BRHI: 104491278(KNG1)
EGZ: 104122294(KNG1)
NNI: 104015695(KNG1)
PCRI: 104029863(KNG1)
PCAO: 104040634(KNG1)
PADL: 103914995(KNG1)
AFOR: 103906262(KNG1)
FGA: 104071955(KNG1)
GSTE: 104259910(KNG1)
CLV: 102087950(KNG1)
MUI: 104547719
PGUU: 104460394
PLET: 104619522(KNG1)
EHS: 104511925(KNG1)
CMAC: 104479437
CUCA: 104057877(KNG1)
TEO: 104384620(KNG1)
BREG: 104643218(KNG1)
OHA: 104335997(KNG1)
ACAR: 104532431(KNG1)
CPEA: 104390868(KNG1)
CVF: 104295530(KNG1)
RTD: 128911013(KNG1)
AAM: 106482222(KNG1)
AROW: 112968595(KNG1)
NPD: 112952494(KNG1)
TGT: 104578046(KNG1)
DNE: 112980150(KNG1)
SCAM: 104145654(KNG1)
ASN: 102372524 112549141
AMJ: 102564037(KNG1)
CPOO: 109308479 109308480
GGN: 109287755 109288034
PSS: 102454442 102454693
CMY: 102931876(KNG1)
CCAY: 125642182(KNG1)
DCC: 119861645(KNG1)
CPIC: 101949273(KNG1)
TST: 117882638(KNG1)
CABI: 116838549(KNG1)
MRV: 120371843(KNG1)
ACS: 100562042(kng1)
ASAO: 132770466(KNG1)
PVT: 110069870 110088341
SUND: 121925417(KNG1)
PBI: 112542793 112542810
PMUR: 114923020(KNG1)
CTIG: 120298285(KNG1)
PGUT: 117678139(KNG1)
APRI: 131200427(KNG1)
NSS: 113422708 113422709
VKO: 123025566
PMUA: 114598043(KNG1)
PRAF: 128414813(KNG1)
ZVI: 118093880(KNG1)
HCG: 128351730(KNG1)
STOW: 125438505(KNG1)
EMC: 129332944(KNG1)
XLA: 108718071(kng1.S) 494833(kng1.L)
XTR: 100038066(kng1)
NPR: 108795792 108795800
BBUF: 120997924 120997925
BGAR: 122934424 122936091 122936275 122936326
MUO: 115478505
GSH: 117366973(KNG1)
DRE: 449808(kng1)
SRX: 107747932 107752185
SANH: 107655274 107698046
SGH: 107566876
CCAR: 109047332 109057356
CAUA: 113039787 113065197
CGIB: 127943322 127987434
PTET: 122334064(kng1)
LROH: 127153892(kng1)
OMC: 131529742(kng1)
PPRM: 120468735(kng1)
RKG: 130101984(kng1)
MAMB: 125254806(kng1)
CIDE: 127521381
CERY: 137029010(kng1)
MASI: 127438516 127438722
TROS: 130550042(kng1)
TDW: 130429497(kng1)
MANU: 129453316(kng1) 129453844
IPU: 108271383
IFU: 128614160(kng1)
PHYP: 113536500
SMEO: 124390894(kng1)
TFD: 113650358(kng1)
TVC: 132854756(kng1)
TRN: 134331454(kng1)
AMEX: 103045176(kng1)
CMAO: 118818642(kng1)
EEE: 113577831(kng1)
CHAR: 105913166(kng1)
TRU: 101067074
TFS: 130529353(kng1)
TNG: GSTEN00013007G001
LCO: 104933268
NCC: 104960973(kng1)
TBEN: 117495885(kng1)
CGOB: 115007307
PGEO: 117445795(kng1)
GACU: 117542379(kng1)
EMAC: 134869574(kng1)
ELY: 117253449
EFO: 125896194(kng1)
PLEP: 121964002(kng1)
SLUC: 116038102(kng1)
ECRA: 117950010(kng1)
ESP: 116695419
PFLV: 114561706(kng1)
GAT: 120823576(kng1)
PPUG: 119217099(kng1)
AFB: 129094817(kng1)
CLUM: 117729837(kng1)
PSWI: 130193755(kng1)
MSAM: 119900337(kng1)
SCHU: 122878179(kng1)
CUD: 121511806(kng1)
ALAT: 119028007(kng1)
ASTR: 137599066(kng1)
MZE: 101463563
ONL: 100705815
OAU: 116315476(kng1)
OLA: 101173293
OML: 112150458(kng1)
CSAI: 133458578(kng1)
XMA: 102229943(kng1)
XCO: 114150558(kng1)
XHE: 116725674
PRET: 103463110
PFOR: 103155248
PLAI: 106946035
PMEI: 106928988
GAF: 122838944(kng1)
PPRL: 129378157(kng1)
CVG: 107096591
CTUL: 119789896(kng1)
GMU: 124873578(kng1)
NFU: 107392979
KMR: 108238425(kng1)
ALIM: 106526080
NWH: 119430524(kng1)
AOCE: 111588471
MCEP: 125009385(kng1)
CSEM: 103396573
POV: 109640233
SSEN: 122780864(kng1)
HHIP: 117760508(kng1)
HSP: 118121034(kng1)
PPLT: 128447886(kng1)
SMAU: 118318001(kng1)
LCF: 108880107(kng1)
SDU: 111223969
SLAL: 111671655
XGL: 120791193(kng1)
HCQ: 109524524
SSCV: 125976280
SBIA: 133503585(kng1)
PEE: 133406592(kng1)
PTAO: 133480431(kng1)
BPEC: 110160547
BSPL: 114853451(kng1)
SJO: 128361355(kng1)
SASA: 106584303 106613935
STRU: 115158426 115192470
OTW: 112248444 112251048
OMY: 110521592 110524468
OGO: 123996909 124037793
ONE: 115108458 115145042
OKI: 109897963 109902650
OKE: 118359106 118391540
SALP: 111972238 111975376
SNH: 120052534 120054877
CCLU: 121533377 121540221
ELS: 105025899(kng1)
SFM: 108937290(kng1)
PKI: 111860470(kng1)
AANG: 118225525(kng1)
LOC: 102695287
PSPA: 121322752(kng1) 121326551
ARUT: 117417080 117423273
LCM: 102364078(KNG1)
CMK: 103176979 103182340
CPLA: 122556055
LERI: 129703249 129703250 129707816
BFO: 118412913 118415753
HHAL: 106686791
PPOI: 119093293 119109024
 » show all
Reference
PMID:23874198
  Authors
Taylor SL, Wahl-Jensen V, Copeland AM, Jahrling PB, Schmaljohn CS
  Title
Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system.
  Journal
PLoS Pathog 9:e1003470 (2013)
DOI:10.1371/journal.ppat.1003470
  Sequence
[hsa:3827]
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