Homo sapiens (human): 3827 Help Entry 3827              CDS       T01001                                  Symbol KNG1, BDK, BK, HAE6, HK, HMWK, KNG Name (RefSeq) kininogen 1   KO K03898   kininogen Organism hsa  Homo sapiens (human) Pathway hsa04022   cGMP-PKG signaling pathway hsa04071   Sphingolipid signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04610   Complement and coagulation cascades hsa04750   Inflammatory mediator regulation of TRP channels hsa04810   Regulation of actin cytoskeleton hsa05142   Chagas disease hsa05143   African trypanosomiasis hsa05200   Pathways in cancer Network nt06514  Coagulation cascade   Element N01517   Kallikrein-kinin system, HMWK to bradykinin Disease H01006   Hereditary angioedema Drug target Kallidinogenase:  D03330<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04071 Sphingolipid signaling pathway     3827 (KNG1)    04022 cGMP-PKG signaling pathway     3827 (KNG1)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3827 (KNG1)  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     3827 (KNG1)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     3827 (KNG1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3827 (KNG1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     3827 (KNG1)   09174 Infectious disease: parasitic    05142 Chagas disease     3827 (KNG1)    05143 African trypanosomiasis     3827 (KNG1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     3827 (KNG1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     3827 (KNG1) Peptidases and inhibitors [BR:hsa01002]  Peptidase inhibitors   Family I25: cystatin family    3827 (KNG1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of hepatic cells    3827 (KNG1)   Exosomal proteins of other cancer cells    3827 (KNG1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Cystatin Cathelicidins Spp-24 Bradykinin Motif Other DBs NCBI-GeneID:  3827 NCBI-ProteinID:  NP_001095886 OMIM:  612358 HGNC:  6383 Ensembl:  ENSG00000113889 CPD:  C00306 C16008 C01505 UniProt:  P01042 Structure PDB LinkDB All DBs Position 3:186717359..186744410 Genome browser AA seq 644 aa AA seqDB search MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS NT seq 1935 nt NT seq  +upstreamnt  +downstreamnt atgaaactaattaccatccttttcctctgctccaggctgctactaagtttaacccaggaa tcacagtccgaggaaattgactgcaatgacaaggatttatttaaagctgtggatgctgct ctgaagaaatataacagtcaaaaccaaagtaacaaccagtttgtattgtaccgcataact gaagccactaagacggttggctctgacacgttttattccttcaagtacgaaatcaaggag ggggattgtcctgttcaaagtggcaaaacctggcaggactgtgagtacaaggatgctgca aaagcagccactggagaatgcacggcaaccgtggggaagaggagcagtacgaaattctcc gtggctacccagacctgccagattactccagccgagggccctgtggtgacagcccagtac gactgcctcggctgtgtgcatcctatatcaacgcagagcccagacctggagcccattctg agacacggcattcagtactttaacaacaacactcaacattcctccctcttcatgcttaat gaagtaaaacgggcccaaagacaggtggtggctggattgaactttcgaattacctactca attgtgcaaacgaattgttccaaagagaattttctgttcttaactccagactgcaagtcc ctttggaatggtgataccggtgaatgtacagataatgcatacatcgatattcagctacga attgcttccttctcacagaactgtgacatttatccagggaaggattttgtacaaccacct accaagatttgcgtgggctgccccagagatatacccaccaacagcccagagctggaggag acactgactcacaccatcacaaagcttaatgcagagaataacgcaactttctatttcaag attgacaatgtgaaaaaagcaagagtacaggtggtggctggcaagaaatattttattgac ttcgtggccagggaaaccacatgttccaaggaaagtaatgaagagttgaccgaaagctgt gagaccaaaaaacttggccaaagcctagattgcaacgctgaagtttatgtggtaccctgg gagaaaaaaatttaccctactgtcaactgtcaaccactgggaatgatctcactgatgaaa aggcctccaggtttttcacctttccgatcatcacgaataggggaaataaaagaagaaaca actgtaagtccaccccacacttccatggcacctgcacaagatgaagagcgggattcagga aaagaacaagggcatactcgtagacatgactggggccatgaaaaacaaagaaaacataat cttggccatggccataaacatgaacgtgaccaagggcatgggcaccaaagaggacatggc cttggccatggacacgaacaacagcatggtcttggtcatggacataagttcaaacttgat gatgatcttgaacaccaagggggccatgtccttgaccatggacataagcataagcatggt catggccacggaaaacataaaaataaaggcaaaaagaatggaaagcacaatggttggaaa acagagcatttggcaagctcttctgaagacagtactacaccttctgcacagacacaagag aagacagaagggccaacacccatcccttccctagccaagccaggtgtaacagttaccttt tctgactttcaggactctgatctcattgcaactatgatgcctcctatatcaccagctccc atacagagtgatgacgattggatccctgatatccagatagacccaaatggcctttcattt aacccaatatcagattttccagacacgacctccccaaaatgtcctggacgcccctggaag tcagttagtgaaattaatccaaccacacaaatgaaagaatcttattatttcgatctcact gatggcctttcttaa

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