KEGG   ORTHOLOGY: K03909
Entry
K03909                      KO                                     
Symbol
TFPI
Name
tissue factor pathway inhibitor
Pathway
map04610  Complement and coagulation cascades
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    K03909  TFPI; tissue factor pathway inhibitor
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K03909  TFPI; tissue factor pathway inhibitor
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K03909  TFPI; tissue factor pathway inhibitor
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I2: Kunitz - BPTI family
   K03909  TFPI; tissue factor pathway inhibitor
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   K03909  TFPI; tissue factor pathway inhibitor
Other DBs
GO: 0004867
Genes
HSA: 7035(TFPI)
PTR: 470603(TFPI)
PPS: 100974935(TFPI)
GGO: 101150295(TFPI)
PON: 100171528(TFPI)
NLE: 100604816(TFPI)
MCC: 613026(TFPI)
MCF: 102119734(TFPI)
CSAB: 103217493(TFPI)
CATY: 105579927(TFPI)
PANU: 101021304(TFPI)
TGE: 112636101(TFPI)
RRO: 104667750(TFPI)
RBB: 108535422(TFPI)
TFN: 117094749(TFPI)
PTEH: 111542818(TFPI)
CJC: 100391706(TFPI)
SBQ: 101041187(TFPI)
CSYR: 103276413(TFPI)
MMUR: 105879303(TFPI)
LCAT: 123643562(TFPI)
OGA: 100960539(TFPI)
MMU: 21788(Tfpi)
MCAL: 110288305(Tfpi)
MPAH: 110318900(Tfpi)
RNO: 29436(Tfpi)
MCOC: 116090390(Tfpi)
MUN: 110551966(Tfpi)
CGE: 100760115(Tfpi)
MAUA: 101825370(Tfpi)
PLEU: 114701612(Tfpi)
MORG: 121439312(Tfpi)
MFOT: 126487620
AAMP: 119819144(Tfpi)
NGI: 103728762(Tfpi)
HGL: 101710461(Tfpi)
CPOC: 100727170(Tfpi)
CCAN: 109698481(Tfpi)
DORD: 105996471(Tfpi)
DSP: 122115052(Tfpi)
NCAR: 124980760
OCU: 100009401(TFPI)
OPI: 101534178(TFPI)
TUP: 102493222(TFPI)
CFA: 403921(TFPI)
CLUD: 112668244(TFPI)
VVP: 112931061(TFPI)
VLG: 121471992(TFPI)
AML: 100467371(TFPI)
UMR: 103659659(TFPI)
UAH: 113250680(TFPI)
UAR: 123798120(TFPI)
ELK: 111145643
LLV: 125095218
MPUF: 101693601(TFPI)
ORO: 101370650(TFPI)
EJU: 114225315(TFPI)
ZCA: 113919346(TFPI)
MLX: 118012233(TFPI)
NSU: 110592213(TFPI)
FCA: 101098813(TFPI)
PYU: 121030807(TFPI)
PBG: 122481549(TFPI)
LRUF: 124515924
PTG: 102967553(TFPI)
PPAD: 109274268(TFPI)
AJU: 106976531(TFPI)
HHV: 120241463(TFPI)
BTA: 508763(TFPI)
BOM: 102280267(TFPI)
BIU: 109565684(TFPI)
BBUB: 102409335(TFPI)
CHX: 102185317(TFPI)
OAS: 101120391(TFPI)
ODA: 120854014(TFPI)
CCAD: 122453847(TFPI)
SSC: 100155068(TFPI)
CFR: 102507096(TFPI)
CBAI: 105072913(TFPI)
CDK: 105099010(TFPI)
VPC: 102536993(TFPI)
BACU: 103003675(TFPI)
LVE: 103085229(TFPI)
OOR: 101287826(TFPI)
DLE: 111171643(TFPI)
PCAD: 102989097(TFPI)
PSIU: 116756702(TFPI)
ECB: 100068873(TFPI)
EPZ: 103549925(TFPI)
EAI: 106838694(TFPI)
MNA: 107524072(TFPI)
HAI: 109372705(TFPI)
DRO: 112305840(TFPI) 112305841
SHON: 118985324(TFPI)
AJM: 119062136(TFPI)
PDIC: 114494809(TFPI)
PHAS: 123805976(TFPI)
MMF: 118625022(TFPI)
RFQ: 117025452(TFPI)
PALE: 102880882(TFPI)
PGIG: 120597565(TFPI)
PVP: 105289636(TFPI)
RAY: 107513608(TFPI)
TOD: 119256016(TFPI)
SARA: 101553832(TFPI)
LAV: 100670685(TFPI)
TMU: 101359751
DNM: 101445919(TFPI)
MDO: 100028266(TFPI)
GAS: 123242167(TFPI)
SHR: 100932876(TFPI)
PCW: 110201717(TFPI)
OAA: 100086245(TFPI)
GGA: 423989(TFPI)
PCOC: 116235939(TFPI)
MGP: 100542380(TFPI)
CJO: 107316437(TFPI)
NMEL: 110399465(TFPI)
APLA: 101794822(TFPI)
ACYG: 106034541(TFPI)
AFUL: 116490468(TFPI)
TGU: 100228168(TFPI)
LSR: 110476181(TFPI)
SCAN: 103814557(TFPI)
PMOA: 120511539(TFPI)
OTC: 121335449(TFPI)
PRUF: 121364390(TFPI)
GFR: 102036504(TFPI)
FAB: 101808152(TFPI)
PHI: 102112768(TFPI)
PMAJ: 107207694(TFPI)
CCW: 104693724(TFPI)
CBRC: 103612584(TFPI)
ETL: 114057771(TFPI)
ZAB: 102065897(TFPI)
ACHL: 103804278(TFPI)
FPG: 101913841(TFPI)
FCH: 102058471(TFPI)
CLV: 102096856(TFPI)
EGZ: 104130556(TFPI)
NNI: 104015298(TFPI)
PLET: 104619369
PCRI: 104025924
ACUN: 113482427(TFPI)
TALA: 104366866(TFPI)
PADL: 103926163(TFPI)
AFOR: 103908572(TFPI)
ACHC: 115343214(TFPI)
HALD: 104316269
CCRI: 104162377(TFPI)
CSTI: 104560852
EHS: 104506125(TFPI)
CMAC: 104478860
MUI: 104543802(TFPI)
FGA: 104077050
GSTE: 104259183(TFPI)
LDI: 104352295(TFPI)
MNB: 103775402(TFPI)
OHA: 104328403(TFPI)
NNT: 104400965
DPUB: 104309849(TFPI)
ACAR: 104522482(TFPI)
AAM: 106499287(TFPI)
AROW: 112967679(TFPI)
NPD: 112942748(TFPI)
TGT: 104571881(TFPI)
DNE: 112979922(TFPI)
SCAM: 104138612(TFPI)
ASN: 102388104(TFPI) 112551386
AMJ: 102572762(TFPI) 109280193
CPOO: 109313292 109323023(TFPI)
GGN: 109292347 109301830(TFPI)
PSS: 102457418(TFPI)
CMY: 102938937(TFPI)
CPIC: 101945146(TFPI)
TST: 117884715(TFPI)
CABI: 116831346(TFPI)
MRV: 120374678(TFPI) 120380398
ACS: 100556464(tfpi) 103280506
PVT: 110070289 110088390(TFPI)
SUND: 121918947(TFPI)
PBI: 103065787(TFPI)
PMUR: 107297037(TFPI)
CTIG: 120310470(TFPI)
TSR: 106550122(TFPI)
PGUT: 117672490(TFPI)
VKO: 123021824(TFPI)
PMUA: 114584614(TFPI)
ZVI: 118083983(TFPI)
GJA: 107117285(TFPI)
STOW: 125443757(TFPI)
RTEM: 120941047
DRE: 359833(tfpia)
PPRM: 120459791(tfpia)
MAMB: 125270639(tfpia)
IPU: 108266850(tfpia) 108277053(wu:fb59d01)
SMEO: 124383141(tfpia)
TFD: 113650663(tfpia)
AMEX: 103025270
TRU: 101078065
LCO: 104930424
NCC: 104940995
CGOB: 115026134
ELY: 117251731(tfpia)
EFO: 125899733(tfpia)
PLEP: 121949318
SLUC: 116047623(tfpia)
ECRA: 117952910(tfpia)
ESP: 116698190
PFLV: 114564333
GAT: 120833791(tfpia)
PPUG: 119228351(tfpia)
MSAM: 119903831(tfpia)
CUD: 121522770(tfpia)
ALAT: 119026315(tfpia)
MZE: 101471591
ONL: 112844144
OAU: 116334051(tfpia)
OLA: 101174546
OML: 112154769(tfpia)
XMA: 102235971
XCO: 114148958
XHE: 116723731
PRET: 103461875
PFOR: 103138148
PLAI: 106955142
PMEI: 106917784
GAF: 122839551(tfpia)
CVG: 107086197
CTUL: 119782131(tfpia)
GMU: 124870970
NFU: 107397072
KMR: 108244305(tfpia)
ALIM: 106532916
NWH: 119418999(tfpia)
AOCE: 111571402
MCEP: 125017898(tfpia)
CSEM: 103392428
POV: 109637428
SSEN: 122759106(tfpia)
HHIP: 117755105(tfpia)
HSP: 118120486(tfpia)
LCF: 108887694
SDU: 111218786
SLAL: 111667394
XGL: 120801667(tfpia)
HCQ: 109515452
BPEC: 110175845
MALB: 109972631
BSPL: 114847483(tfpia)
OGO: 124043808 124044238(tfpia)
CCLU: 121536481(tfpia) 121556407
AANG: 118214619(tfpia)
LOC: 102697566(tfpi)
LCM: 102363540(TFPI)
CMK: 103176522(tfpia)
RTP: 109931976(tfpi)
BFO: 118416449
DHE: 111594822
LHU: 105670214
BMOR: 101736287
BANY: 112047574
ZCE: 119835721
OFU: 114365016
PCLA: 123760309
EAF: 111710527
PPOI: 119100765
DSV: 119458997
PTEP: 107442689
SDM: 118184052
PMAX: 117343337
LAK: 106155185
NVE: 5513711
EPA: 110242943
DGT: 114536299
 » show all
Reference
PMID:2452157
  Authors
Wun TC, Kretzmer KK, Girard TJ, Miletich JP, Broze GJ Jr
  Title
Cloning and characterization of a cDNA coding for the lipoprotein-associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains.
  Journal
J Biol Chem 263:6001-4 (1988)
  Sequence
[hsa:7035]
Reference
  Authors
Wood JP, Bunce MW, Maroney SA, Tracy PB, Camire RM, Mast AE
  Title
Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation.
  Journal
Proc Natl Acad Sci U S A 110:17838-43 (2013)
DOI:10.1073/pnas.1310444110
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