Homo sapiens (human): 7035
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Entry
7035 CDS
T01001
Symbol
TFPI, EPI, LACI, TFI, TFPI1
Name
(RefSeq) tissue factor pathway inhibitor isoform a precursor
KO
K03909
tissue factor pathway inhibitor
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Drug target
Concizumab:
D11847
<JP/US>
Marstacimab:
D11261
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
7035 (TFPI)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
7035 (TFPI)
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
7035 (TFPI)
Peptidases and inhibitors [BR:
hsa01002
]
Peptidase inhibitors
Family I2: Kunitz - BPTI family
7035 (TFPI)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
7035 (TFPI)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Kunitz_BPTI
Motif
Other DBs
NCBI-GeneID:
7035
NCBI-ProteinID:
NP_001316168
OMIM:
152310
HGNC:
11760
UniProt:
P10646
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(187464230..187554435)
Genome browser
AA seq
304 aa
AA seq
DB search
MIYTMKKVHALWASVCLLLNLAPAPLNADSEEDEEHTIITDTELPPLKLMHSFCAFKADD
GPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRIIKTTLQQE
KPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICEDGPN
GFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRFYYNSVIG
KCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRISKGGLIKTKRKRKKQRVKIAYEEIF
VKNM
NT seq
915 nt
NT seq
+upstream
nt +downstream
nt
atgatttacacaatgaagaaagtacatgcactttgggcttctgtatgcctgctgcttaat
cttgcccctgcccctcttaatgctgattctgaggaagatgaagaacacacaattatcaca
gatacggagttgccaccactgaaacttatgcattcattttgtgcattcaaggcggatgat
ggcccatgtaaagcaatcatgaaaagatttttcttcaatattttcactcgacagtgcgaa
gaatttatatatgggggatgtgaaggaaatcagaatcgatttgaaagtctggaagagtgc
aaaaaaatgtgtacaagagataatgcaaacaggattataaagacaacattgcaacaagaa
aagccagatttctgctttttggaagaagatcctggaatatgtcgaggttatattaccagg
tatttttataacaatcagacaaaacagtgtgaacgtttcaagtatggtggatgcctgggc
aatatgaacaattttgagacactggaagaatgcaagaacatttgtgaagatggtccgaat
ggtttccaggtggataattatggaacccagctcaatgctgtgaataactccctgactccg
caatcaaccaaggttcccagcctttttgaatttcacggtccctcatggtgtctcactcca
gcagacagaggattgtgtcgtgccaatgagaacagattctactacaattcagtcattggg
aaatgccgcccatttaagtacagtggatgtgggggaaatgaaaacaattttacttccaaa
caagaatgtctgagggcatgtaaaaaaggtttcatccaaagaatatcaaaaggaggccta
attaaaaccaaaagaaaaagaaagaagcagagagtgaaaatagcatatgaagaaattttt
gttaaaaatatgtga
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