ORTHOLOGY: K03958
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Entry
K03958 KO
Symbol
NDUFB2
Name
NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
Pathway
map00190
Oxidative phosphorylation
map01100
Metabolic pathways
map04714
Thermogenesis
map04723
Retrograde endocannabinoid signaling
map04932
Non-alcoholic fatty liver disease
map05010
Alzheimer disease
map05012
Parkinson disease
map05014
Amyotrophic lateral sclerosis
map05016
Huntington disease
map05020
Prion disease
map05022
Pathways of neurodegeneration - multiple diseases
map05208
Chemical carcinogenesis - reactive oxygen species
map05415
Diabetic cardiomyopathy
Module
M00147
NADH dehydrogenase (ubiquinone) 1 beta subcomplex
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
09159 Environmental adaptation
04714 Thermogenesis
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
09164 Neurodegenerative disease
05010 Alzheimer disease
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
05012 Parkinson disease
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
05014 Amyotrophic lateral sclerosis
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
05016 Huntington disease
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
05020 Prion disease
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
05022 Pathways of neurodegeneration - multiple diseases
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
K03958 NDUFB2; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2
BRITE hierarchy
Other DBs
TC:
3.D.1.6
Genes
HSA:
4708
(NDUFB2)
PTR:
463780
(NDUFB2)
PPS:
100972346
(NDUFB2)
GGO:
109025103
(NDUFB2)
PON:
100442655
(NDUFB2)
PPYG:
129041339
(NDUFB2)
NLE:
100583181
(NDUFB2)
HMH:
116814430
(NDUFB2)
SSYN:
129485089
(NDUFB2)
MCC:
693431
(NDUFB2)
MCF:
101865240
(NDUFB2)
MTHB:
126949662
MNI:
105471277
(NDUFB2)
CSAB:
103227023
(NDUFB2)
CATY:
105589670
(NDUFB2)
PANU:
101021838
(NDUFB2)
TGE:
112620355
(NDUFB2)
MLEU:
105550513
(NDUFB2)
RRO:
104659699
(NDUFB2)
RBB:
108541536
(NDUFB2)
TFN:
117072298
(NDUFB2)
PTEH:
111521523
(NDUFB2)
CANG:
105510354
105511180
(NDUFB2)
CJC:
100403449
(NDUFB2)
SBQ:
101039525
101051290
(NDUFB2)
CIMI:
108283416
(NDUFB2)
ANAN:
105711098
105713648
(NDUFB2)
CSYR:
103271180
MMUR:
105873243
(NDUFB2)
LCAT:
123647646
(NDUFB2)
PCOQ:
105814705
(NDUFB2)
OGA:
100943147
(NDUFB2)
MMU:
68198
(Ndufb2)
MCAL:
110296765
(Ndufb2)
MPAH:
110317149
(Ndufb2)
RNO:
362344
(Ndufb2)
MCOC:
116098773
(Ndufb2)
ANU:
117721060
(Ndufb2)
MUN:
110545792
(Ndufb2)
CGE:
100774095
(Ndufb2)
MAUA:
101842033
(Ndufb2)
PROB:
127214232
(Ndufb2)
PLEU:
114706832
(Ndufb2)
MORG:
121435543
121458750
121463417
MFOT:
126487768
126505152
AAMP:
119800598
119806913
(Ndufb2)
NGI:
103726106
(Ndufb2)
HGL:
101702077
(Ndufb2)
CPOC:
100718422
(Ndufb2)
CCAN:
109682016
(Ndufb2)
DORD:
105989469
(Ndufb2)
DSP:
122105938
(Ndufb2)
PLOP:
125347227
(Ndufb2)
NCAR:
124990972
MMMA:
107149001
(Ndufb2)
OCU:
100350704
OPI:
101526600
(NDUFB2)
TUP:
102476975
(NDUFB2)
GVR:
103596179
(NDUFB2)
CFA:
100683846
(NDUFB2)
CLUD:
112649336
112650992
(NDUFB2)
VVP:
112906994
(NDUFB2)
VLG:
121482582
121489530
(NDUFB2)
NPO:
129516190
(NDUFB2)
129518682
AML:
100469603
(NDUFB2)
UMR:
103669030
(NDUFB2)
UAH:
113265140
(NDUFB2)
UAR:
123788874
(NDUFB2)
ELK:
111151936
LLV:
125080587
MPUF:
101674641
(NDUFB2)
MNP:
132008625
132015204
132015638
(NDUFB2)
MLK:
131829846
(NDUFB2)
131830331
NVS:
122905137
(NDUFB2)
ORO:
101376585
(NDUFB2)
EJU:
114211582
(NDUFB2)
ZCA:
113911619
(NDUFB2)
MLX:
118021161
(NDUFB2)
NSU:
110582840
(NDUFB2)
LWW:
102729262
102748548
(NDUFB2)
FCA:
101082389
(NDUFB2)
PYU:
121028242
(NDUFB2)
PCOO:
112866888
(NDUFB2)
PBG:
122488404
(NDUFB2)
PVIV:
125160125
(NDUFB2)
LRUF:
124524697
PTG:
102968764
(NDUFB2)
PPAD:
109269112
(NDUFB2)
PUC:
125930928
AJU:
106970440
HHV:
120232946
(NDUFB2)
BTA:
327713
(NDUFB2)
BOM:
102278908
(NDUFB2)
BIU:
109557699
(NDUFB2)
BBUB:
102400746
(NDUFB2)
BBIS:
104999382
(NDUFB2)
CHX:
102174090
(NDUFB2)
OAS:
101107189
(NDUFB2)
BTAX:
128046972
(NDUFB2)
ODA:
120877658
(NDUFB2)
CCAD:
122438724
(NDUFB2)
MBEZ:
129552713
(NDUFB2)
SSC:
100513895
(NDUFB2)
CFR:
102523839
(NDUFB2)
CBAI:
105063021
(NDUFB2)
CDK:
105091662
(NDUFB2)
VPC:
102528538
(NDUFB2)
BACU:
103009696
(NDUFB2)
103017454
BMUS:
118898350
118900687
(NDUFB2)
LVE:
103078980
(NDUFB2)
OOR:
101277437
(NDUFB2)
101278952
101282167
DLE:
111177666
(NDUFB2)
111181221
PCAD:
102983006
102987193
112066265
PSIU:
116753859
116759303
(NDUFB2)
NASI:
112398101
(NDUFB2)
ECB:
100064695
(NDUFB2)
EPZ:
103555337
(NDUFB2)
EAI:
106842621
(NDUFB2)
MYB:
102260343
(NDUFB2)
MYD:
102760710
(NDUFB2)
MMYO:
118666341
(NDUFB2)
MLF:
102420558
(NDUFB2)
MDT:
132242839
(NDUFB2)
PKL:
118713927
(NDUFB2)
EFUS:
103294086
(NDUFB2)
MNA:
107531090
(NDUFB2)
DRO:
112299902
(NDUFB2)
SHON:
118989074
(NDUFB2)
AJM:
119044477
(NDUFB2)
PDIC:
114508121
(NDUFB2)
PHAS:
123829673
(NDUFB2)
MMF:
118620023
(NDUFB2)
PPAM:
129063444
(NDUFB2)
HAI:
109393732
109395593
(NDUFB2)
RFQ:
117018092
(NDUFB2)
PALE:
102878640
(NDUFB2)
PGIG:
120601134
(NDUFB2)
PVP:
105291606
(NDUFB2)
RAY:
107504059
(NDUFB2)
MJV:
108387835
(NDUFB2)
TOD:
119247798
(NDUFB2)
SARA:
101550944
(NDUFB2)
SETR:
126012058
(NDUFB2)
126026123
LAV:
100664407
(NDUFB2)
TMU:
101345814
ETF:
101656638
(NDUFB2)
DNM:
101411540
(NDUFB2)
MDO:
100023986
(NDUFB2)
GAS:
123250730
(NDUFB2)
SHR:
100930539
(NDUFB2)
AFZ:
127539364
PCW:
110216136
(NDUFB2)
TVP:
118830684
118832903
118844367
118850802
(NDUFB2)
OAA:
100086429
(NDUFB2)
GGA:
418118
(NDUFB2)
PCOC:
116226813
(NDUFB2)
MGP:
104911618
(NDUFB2)
CJO:
107315924
(NDUFB2)
TPAI:
128073535
(NDUFB2)
LMUT:
125697400
(NDUFB2)
NMEL:
110394476
(NDUFB2)
APLA:
113840373
(NDUFB2)
ACYG:
136790941
(NDUFB2)
CATA:
118259214
(NDUFB2)
AFUL:
116497459
(NDUFB2)
TGU:
100227257
(NDUFB2)
LSR:
110482599
(NDUFB2)
SCAN:
103819613
(NDUFB2)
PMOA:
120501720
(NDUFB2)
OTC:
121332799
(NDUFB2)
PRUF:
121364312
(NDUFB2)
FAB:
101813335
(NDUFB2)
OMA:
130263636
(NDUFB2)
PHI:
102105379
(NDUFB2)
PMAJ:
107204195
(NDUFB2)
ETL:
114056185
(NDUFB2)
ZAB:
102072584
(NDUFB2)
ZLE:
135461137
(NDUFB2)
SVG:
106849399
(NDUFB2)
MMEA:
130588708
(NDUFB2)
HRT:
120751659
(NDUFB2)
SATI:
136361657
(NDUFB2)
SHAB:
115605857
(NDUFB2)
TALA:
122153692
(NDUFB2)
ACHC:
115352784
(NDUFB2)
HLE:
104831035
(NDUFB2)
AGEN:
126047629
GCL:
127024778
NNI:
104012396
(NDUFB2)
MUI:
104538063
(NDUFB2)
RTD:
128904589
(NDUFB2)
AROW:
112974665
(NDUFB2)
NPD:
112945647
(NDUFB2)
DNE:
112995044
(NDUFB2)
AMJ:
102564435
(NDUFB2)
CPOO:
109316528
(NDUFB2)
GGN:
109296414
(NDUFB2)
CMY:
102938374
(NDUFB2)
CCAY:
125623661
125627010
(NDUFB2)
DCC:
119849966
(NDUFB2)
CPIC:
122173872
(NDUFB2)
TST:
117879080
117881811
(NDUFB2)
CABI:
116826029
116826447
(NDUFB2)
116833365
MRV:
120380230
(NDUFB2)
ACS:
100559985
(ndufb2)
ASAO:
132775825
(NDUFB2)
PVT:
110082699
(NDUFB2)
SUND:
121931838
(NDUFB2)
PBI:
103054814
(NDUFB2)
PMUR:
107288687
(NDUFB2)
CTIG:
120316370
(NDUFB2)
TSR:
106550526
(NDUFB2)
PGUT:
117655370
(NDUFB2)
APRI:
131201622
(NDUFB2)
PTEX:
113452134
(NDUFB2)
NSS:
113432842
(NDUFB2)
VKO:
123028861
(NDUFB2)
PMUA:
114604964
(NDUFB2)
PRAF:
128406298
128422742
(NDUFB2)
ZVI:
118090616
(NDUFB2)
HCG:
128326904
(NDUFB2)
GJA:
107108794
(NDUFB2)
STOW:
125435849
(NDUFB2)
EMC:
129336310
(NDUFB2)
XLA:
379950
(ndufb2.S)
XTR:
100127720
(ndufb2)
NPR:
108793042
(NDUFB2)
RTEM:
120932894
(NDUFB2)
BBUF:
121005896
(NDUFB2)
MUO:
115478882
(NDUFB2)
GSH:
117367172
(NDUFB2)
DRE:
393764
(ndufb2)
SRX:
107710676
107755897
SANH:
107680035
107694192
SGH:
107578274
107590801
CCAR:
109050708
109105908
CAUA:
113048212
113061849
CGIB:
127956347
127973238
PTET:
122343273
(ndufb2)
LROH:
127163771
(ndufb2)
OMC:
131538937
(ndufb2)
PPRM:
120476925
(ndufb2)
RKG:
130082670
(ndufb2)
MAMB:
125244824
(ndufb2)
CIDE:
127510804
CERY:
137024552
(ndufb2)
MASI:
127435436
127436497
TROS:
130547857
(ndufb2)
TDW:
130421489
(ndufb2)
MANU:
129432308
(ndufb2)
IPU:
100528777
(ndufb2)
IFU:
128623308
(ndufb2)
SMEO:
124401167
(ndufb2)
TFD:
113651869
(ndufb2)
TVC:
132859103
(ndufb2)
TRN:
134316594
(ndufb2)
AMEX:
103039725
(ndufb2)
CMAO:
118812320
(ndufb2)
EEE:
113569301
(ndufb2)
CHAR:
105896736
(ndufb2)
TRU:
101063599
(ndufb2)
TFS:
130519180
(ndufb2)
TNG:
GSTEN00021510G001
LCO:
104925312
(ndufb2)
NCC:
104968058
(ndufb2)
TBEN:
117484913
(ndufb2)
CGOB:
115028245
(ndufb2)
PGEO:
117439016
(ndufb2)
GACU:
117559174
(ndufb2)
EMAC:
134879092
(ndufb2)
ELY:
117249056
(ndufb2)
EFO:
125882686
(ndufb2)
PLEP:
121961639
(ndufb2)
SLUC:
116060182
(ndufb2)
ECRA:
117938971
(ndufb2)
ESP:
116673312
(ndufb2)
PFLV:
114550569
(ndufb2)
GAT:
120818321
(ndufb2)
PPUG:
119210402
(ndufb2)
AFB:
129112735
(ndufb2)
CLUM:
117725972
(ndufb2)
PSWI:
130200815
(ndufb2)
MSAM:
119918235
(ndufb2)
SCHU:
122871320
(ndufb2)
CUD:
121505653
(ndufb2)
ALAT:
119032436
(ndufb2)
MZE:
101483759
(ndufb2)
ONL:
100706408
(ndufb2)
OAU:
116334668
(ndufb2)
OLA:
101156374
(ndufb2)
OML:
112155856
(ndufb2)
CSAI:
133424502
(ndufb2)
XMA:
102228565
(ndufb2)
XCO:
114160662
(ndufb2)
XHE:
116736579
(ndufb2)
PRET:
103459109
(ndufb2)
PFOR:
103140217
(ndufb2)
PLAI:
106957555
(ndufb2)
PMEI:
106924676
(ndufb2)
GAF:
122826615
(ndufb2)
PPRL:
129351549
(ndufb2)
129357993
CVG:
107095908
(ndufb2)
CTUL:
119791163
(ndufb2)
GMU:
124883261
(ndufb2)
NFU:
107386398
(ndufb2)
KMR:
108233299
(ndufb2)
ALIM:
106514827
(ndufb2)
NWH:
119428010
(ndufb2)
AOCE:
111569070
(ndufb2)
MCEP:
125000054
(ndufb2)
CSEM:
103382717
(ndufb2)
POV:
109642795
(ndufb2)
SSEN:
122766562
(ndufb2)
HHIP:
117757001
(ndufb2)
HSP:
118101524
(ndufb2)
PPLT:
128428884
(ndufb2)
SMAU:
118286081
(ndufb2)
LCF:
108886208
SDU:
111224553
(ndufb2)
SLAL:
111660047
(ndufb2)
XGL:
120799891
(ndufb2)
HCQ:
109523668
(ndufb2)
SSCV:
125992163
PEE:
133396924
(ndufb2)
PTAO:
133471579
(ndufb2)
BPEC:
110161846
(ndufb2)
MALB:
109969691
(ndufb2)
BSPL:
114862442
(ndufb2)
SJO:
128353230
(ndufb2)
SASA:
106576359
(NDUB2)
106609400
(NDUB2)
STRU:
115180215
115198999
OTW:
112217056
112267831
OMY:
100301658
110490480
OGO:
123994445
124014443
ONE:
115118343
115132993
OKI:
109880580
109884017
OKE:
118377781
118378638
SALP:
111982567
112067749
SNH:
120031904
120050081
CCLU:
121579209
(ndufb2)
ELS:
105023412
(ndufb2)
SFM:
108931564
(ndufb2)
PKI:
111851238
(ndufb2)
AANG:
118231710
(ndufb2)
LOC:
102686827
(ndufb2)
PSPA:
121318512
(ndufb2)
ARUT:
117419670
(ndufb2)
PSEX:
120539448
(ndufb2)
LCM:
102364731
(NDUFB2)
CMK:
103186216
(ndufb2)
RTP:
109912140
(ndufb2)
CPLA:
122559609
(ndufb2)
HOC:
132824954
(ndufb2)
LERI:
129706111
(ndufb2)
PMRN:
116945600
(NDUFB2)
LRJ:
133351416
(NDUFB2)
BFO:
118406758
BBEL:
109471771
SCLV:
120326964
SPU:
764410
LPIC:
129283219
SKO:
102803124
DME:
Dmel_CG40002
(ND-AGGG)
Dmel_CG40472
(CG40472)
DER:
6544442
DSE:
116801081
116801200
116801248
DSI:
Dsimw501_GD26928
(Dsim_GD26928)
Dsimw501_GD27058
(Dsim_GD27058)
Dsimw501_GD28357
(Dsim_GD28357)
Dsimw501_GD29034
(Dsim_GD29034)
DYA:
Dyak_GE28057
DSR:
110179905
DPO:
4811647
DPE:
113567321
DMN:
108157109
DWI:
6647928
DGR:
116805405
DMO:
Dmoj_GI26649
DAZ:
108620394
DNV:
108658300
DHE:
111600839
DVI:
26530948
CCAT:
101453610
BOD:
106621913
RZE:
108362696
AOQ:
129249499
TDA:
119682846
MDE:
101899538
131805486
SCAC:
106091959
LCQ:
111687299
LSQ:
119601231
GFS:
119639527
ECOE:
129940309
CLON:
129615659
HIS:
119658624
AGA:
1273330
ACOZ:
120952237
AARA:
120897219
AMER:
121588502
ASTE:
118504935
AFUN:
125761071
AMOU:
128297874
AALI:
118457858
AAG:
5579021
AALB:
109414398
109415396
ASUA:
134228153
CQU:
CpipJ_CPIJ009076
CPII:
120432387
CNS:
116336638
BCOO:
119069135
AME:
726146
(Ndufb2)
ACER:
108000435
ALAB:
122711636
ADR:
102671348
AFLR:
100865103
BIM:
100743284
BBIF:
117209593
BVK:
117242275
BVAN:
117161332
BTER:
100651178
BAFF:
126926642
BPYO:
122577197
BPAS:
132915524
FVI:
122531613
CCAL:
108627141
OBB:
114878857
OLG:
117605528
MGEN:
117223978
NMEA:
116435243
CGIG:
122395533
SOC:
105192844
MPHA:
105837343
AEC:
105147182
ACEP:
105617525
PBAR:
105428441
VEM:
105563592
HST:
105188912
DQU:
106750501
CFO:
105252396
FEX:
115235577
PGC:
109852855
OBO:
105282179
PCF:
106786886
PFUC:
122516061
VPS:
122628922
VCRB:
124424737
VVE:
124948977
NVI:
100117989
TPRE:
106656270
LHT:
122498065
LBD:
127287728
MDL:
103575209
CGLO:
123261718
FAS:
105265211
DAM:
107041291
AGIF:
122851791
CINS:
118065061
VCAN:
122407823
CCIN:
107270210
DSM:
124406609
NFB:
124185466
AROA:
105690387
TCA:
659363
DPA:
109541886
SOY:
115879329
115879381
AGRG:
126735861
ATD:
109598623
CSET:
123315258
AGB:
108904388
LDC:
111508013
DVV:
114331784
NVL:
108566974
APLN:
108741797
PPYR:
116163109
116167642
OTU:
111413354
BMOR:
101740204
BMAN:
114239772
MSEX:
115449570
DPL:
KGM_208972
BANY:
112050823
MJU:
123867857
NIQ:
126769304
VCD:
124532351
MCIX:
123655280
PMAC:
106720713
PPOT:
106103557
PXU:
106115661
PRAP:
110995176
PBX:
123709706
PNAP:
125063363
ZCE:
119840386
CCRC:
123693294
AAGE:
121727516
HAW:
110383955
HZE:
124631791
TNL:
113500749
SLIU:
111355405
OFU:
114363990
ATRA:
106142817
GMW:
113515569
PXY:
105388708
PGW:
126369327
LGLY:
125224597
CFEL:
113389362
CCRN:
123293338
API:
100302482
(Ndufb2)
115032983
DNX:
107163713
AGS:
114125556
RMD:
113550145
ACOO:
126839009
DVT:
126901481
BTAB:
109029774
CLEC:
106674026
HHAL:
106681113
NLU:
111047788
HVI:
124359104
MQU:
128983082
FOC:
113216630
TPAL:
117640361
ZNE:
110838053
CSEC:
111870190
SGRE:
126282078
BROR:
134539188
IEL:
124161277
FCD:
110846192
DPX:
DAPPUDRAFT_309343
DMK:
116925380
DPZ:
124349863
PVM:
113821849
PJA:
122250434
PCHN:
125036131
PMOO:
119593903
119594185
HAME:
121864915
PCLA:
123761603
PTRU:
123506981
ESN:
126982946
MNZ:
135207577
HAZT:
108675104
EAF:
111702838
LSM:
121124841
PPOI:
119103967
DSV:
119465362
RSAN:
119401902
VJA:
111259351
TUT:
107362668
DPTE:
113794265
DFR:
124498901
CSCU:
111630492
CVS:
136969376
PTEP:
107455849
ABRU:
129961556
LPOL:
106459283
CEL:
CELE_F44G4.2
(ndub-2)
CBR:
CBG_03233
CRQ:
GCK72_005645
LOA:
LOAG_02174
TSP:
Tsp_10274
LGI:
LOTGIDRAFT_236028
PCAN:
112566456
GAE:
121370514
HRF:
124140356
HRJ:
124277828
OED:
125676969
MYI:
110458277
MCAF:
127724288
MMER:
123550862
RPHI:
132723226
DPOL:
127854098
MAEA:
128237235
OBI:
106884103
OSN:
115223002
LJP:
135462031
SMM:
Smp_022460
OVI:
T265_09561
LLON:
135488310
CVR:
CHLNCDRAFT_57885
OLU:
OSTLU_29536
OTA:
OT_ostta14g02270
MIS:
MICPUN_52925
MPP:
MICPUCDRAFT_56938
EHX:
EMIHUDRAFT_122416
» show all
Taxonomy
UniProt
Reference
PMID:
9878551
Authors
Loeffen JL, Triepels RH, van den Heuvel LP, Schuelke M, Buskens CA, Smeets RJ, Trijbels JM, Smeitink JA
Title
cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.
Journal
Biochem Biophys Res Commun 253:415-22 (1998)
DOI:
10.1006/bbrc.1998.9786
Sequence
[hsa:
4708
]
LinkDB
All DBs
DBGET
integrated database retrieval system