KEGG   ORTHOLOGY: K04012
Entry
K04012                      KO                                     

Symbol
CR2, CD21
Name
complement receptor type 2
Pathway
map04610  Complement and coagulation cascades
map04640  Hematopoietic cell lineage
map04662  B cell receptor signaling pathway
map05169  Epstein-Barr virus infection
Disease
H00080  Systemic lupus erythematosus
H00088  Common variable immunodeficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K04012  CR2, CD21; complement receptor type 2
   04610 Complement and coagulation cascades
    K04012  CR2, CD21; complement receptor type 2
   04662 B cell receptor signaling pathway
    K04012  CR2, CD21; complement receptor type 2
 09160 Human Diseases
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    K04012  CR2, CD21; complement receptor type 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K04012  CR2, CD21; complement receptor type 2
CD molecules [BR:ko04090]
 Proteins
  K04012  CD21, CR2; complement component (3d/Epstein Barr virus) receptor 2
Genes
HSA: 1380(CR2)
PPS: 100983119(CR2)
GGO: 101139118(CR2)
PON: 103890063(CR2)
NLE: 100587321(CR2)
MCC: 714202(CR2)
MCF: 102145559(CR2)
CSAB: 103230175(CR2)
CATY: 105576948(CR2)
PANU: 103878155(CR2)
RRO: 104664178(CR2)
RBB: 108535125(CR2)
TFN: 117074329(CR2)
PTEH: 111522745(CR2)
CJC: 108587696(CR2)
SBQ: 101045483(CR2)
MMUR: 105868169
MMU: 12902(Cr2)
MCAL: 110289952(Cr2)
MPAH: 110321620(Cr2)
RNO: 289395(Cr2)
MCOC: 116097050
MUN: 110563671(Cr2)
CGE: 100773072(Cr2)
PLEU: 114687531(Cr2)
NGI: 103727020
HGL: 101704987(Cr2)
CCAN: 109686661(Cr2)
OCU: 108178217(CR2)
OPI: 101528116(CR2)
TUP: 106736072(CR2)
CFA: 490269
VVP: 112910983(CR2)
VLG: 121492856(CR2)
AML: 100482465(CR2)
UMR: 103657661(CR2)
UAH: 113242610(CR2)
ORO: 101379114(CR2)
ELK: 111151001
MPUF: 101687991(CR2)
EJU: 114221931(CR2)
MLX: 118014260(CR2)
FCA: 101094393(CR2)
PYU: 121022445(CR2)
PBG: 122475744(CR2)
PTG: 102963617(CR2)
PPAD: 109255275(CR2)
AJU: 106981813(CR2)
HHV: 120230487(CR2)
BTA: 407126(CR2)
BOM: 102281632(CR2)
BBUB: 102389290(CR2)
CHX: 102186615(CR2)
OAS: 443017(CR2)
ODA: 120879923(CR2)
CCAD: 122452577(CR2)
CFR: 102510063(CR2)
CBAI: 105075416(CR2)
CDK: 105098600(CR2)
BACU: 102998901(CR2)
LVE: 103079671(CR2)
OOR: 101269842(CR2)
DLE: 111184731(CR2)
PCAD: 102977150
ECB: 100057298
EPZ: 103556834(CR2)
EAI: 106842726
MYB: 102240721(CR2) 102255761
MYD: 102761318
MMYO: 118673476(CR2)
PKL: 118721264(CR2)
HAI: 109374503(CR2)
SHON: 118982573(CR2)
AJM: 119056821(CR2)
MMF: 118637139
PALE: 102883716(CR2)
PGIG: 120589495
RAY: 107497825(CR2) 107505212
MJV: 108404128(CR2)
TOD: 119234695
LAV: 111750709(CR2)
SHR: 100914918(CR2)
PCW: 110203606 110219631(CR2)
OAA: 100084581
NMEL: 110388364
TGU: 100223070
LSR: 110473441
SCAN: 103822400
PMOA: 120497637
FCH: 114018057
EGZ: 104131253
AAM: 106490987
AMJ: 102574670
PSS: 112543738
CABI: 116832998
PVT: 110086564
PMUR: 107288378
TSR: 106555378
PGUT: 117664328
CAUA: 113065508
SCLV: 120337291
SKO: 102801828
CBR: CBG16936
LAK: 106153784
 » show all
Reference
PMID:2563370
  Authors
Fujisaku A, Harley JB, Frank MB, Gruner BA, Frazier B, Holers VM
  Title
Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor.
  Journal
J Biol Chem 264:2118-25 (1989)
  Sequence
[hsa:1380]
Reference
  Authors
Prodinger WM
  Title
Complement receptor type two (CR2,CR21): a target for influencing the humoral immune response and antigen-trapping.
  Journal
Immunol Res 20:187-94 (1999)
DOI:10.1007/BF02790402
Reference
PMID:7753047
  Authors
Barel M, Balbo M, Gauffre A, Frade R
  Title
Binding sites of the Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein.
  Journal
Mol Immunol 32:389-97 (1995)
DOI:10.1016/0161-5890(95)00005-Y
  Sequence
[hsa:1380]
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