KEGG ORTHOLOGY: K04175

ORTHOLOGY: K04175

Entry

K04175                      KO

Symbol

CXCR1, IL8RA, CD181

Name

C-X-C chemokine receptor type 1

Pathway

map04060

Cytokine-cytokine receptor interaction

map04061

Viral protein interaction with cytokine and cytokine receptor

map04062

Chemokine signaling pathway

map04072

Phospholipase D signaling pathway

map04144

Endocytosis

map05120

Epithelial cell signaling in Helicobacter pylori infection

Disease

H01563

HIV infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
   04050 Cytokine receptors
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
   04090 CD molecules
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Chemokine
   CXC Chemokine
    K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
Cytokine receptors [BR:ko04050]
Chemokine receptors
  CXC Chemokine
   K04175  CXCR1, IL8RA, CD181; C-X-C chemokine receptor type 1
CD molecules [BR:ko04090]
Proteins
  K04175  CD181, CXCR1; chemokine (C-X-C motif) receptor 1

Other DBs

GO:

0004918

Genes

HSA:	3577(CXCR1)

PTR:	470645(CXCR1)

PPS:	100979257(CXCR1)

GGO:	101152473(CXCR1)

PON:	100459971 100461947

PPYG:

129032076(CXCR1)

NLE:	100580192 100598264

HMH:	116810311(CXCR1) 116810665

SSYN:

129488434(CXCR1)

MCC:	692074(CXCR1)

MCF:	102140902(CXCR1)

MTHB:

126932436

MNI:	105481204(CXCR1)

CSAB:

103217856(CXCR1)

CATY:

105587075

PANU:

101017773(CXCR1)

TGE:	112636637(CXCR1)

MLEU:

105528028(CXCR1)

RRO:	104660012(CXCR1)

TFN:	117094539(CXCR1)

PTEH:

111548396(CXCR1)

CANG:

105504737(CXCR1)

CJC:	100385951(CXCR1)

SBQ:	101037560(CXCR1)

CIMI:

108309044(CXCR1)

ANAN:

105712864(CXCR1)

CSYR:

103276290(CXCR1)

MMUR:

105857710(CXCR1)

LCAT:

123643506(CXCR1)

PCOQ:

105808759(CXCR1)

OGA:	100944056(CXCR1)

MMU:	227288(Cxcr1)

MCAL:

110304464

MPAH:

110321940

RNO:	54258(Cxcr1)

MCOC:

ANU:

ASYL:

MUN:

CGE:

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103727810(Cxcr1)

HGL:	101712235(Cxcr1)

CPOC:

100379619(Cxcr1)

DORD:

105997020(Cxcr1)

DSP:

122107404

PLOP:

125350836(Cxcr1)

NCAR:

124980660

MMMA:

107138687(Cxcr1)

ITI:	101956770(Cxcr1)

OCU:	100328622(CXCR1)

OPI:

101532179

TUP:	102484375(CXCR1)

GVR:	103588922(CXCR1) 103610478

CFA:	478906(CXCR1)

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:	103662893(CXCR1)

UAH:

113250470

UAR:	123779429(CXCR1)

ELK:

LLV:

MNP:

MLK:

NVS:

ORO:	101386791(CXCR1)

EJU:

114200162

ZCA:

118356787

MLX:	118012054(CXCR1)

NSU:	110592162(CXCR1)

LWW:

102734017

FCA:

101085650

PYU:	121031057(CXCR1)

PBG:

PVIV:

LRUF:

LGF:

AJU:

PTG:	102952543(CXCR1)

PPAD:

109265077(CXCR1)

PUC:

125911200

PLEZ:

122226628

HHV:

120232399

BTA:	281863(CXCR1)

BOM:	102269794(CXCR1)

BIU:

109570482

BBUB:

102401761

BBIS:

105003757

CHX:	102189634(CXCR1)

OAS:

101108811

BTAX:

128043368(CXCR1)

CSUM:

138076425

ODA:	120854387(CXCR1)

CCAD:

122426789

MREE:

136163219

OVR:

110128537

MBEZ:

129538412(CXCR1)

SSC:

100515345

CFR:	102512865(CXCR1)

CBAI:

105064001

CDK:	105096070 116151675

VPC:

BACU:

BMUS:

LVE:

OOR:

LALB:

132521646(CXCR1)

DLE:

111171817

PCAD:

102995584(CXCR1)

PSIU:

116757066(CXCR1)

NASI:

112411919(CXCR1)

ECB:

EPZ:

EAI:

MYB:

PKL:

EFUS:

MNA:

DRO:	112307955(CXCR1)

SHON:

118975406(CXCR1)

AJM:	119039546(CXCR1)

PDIC:

114494642(CXCR1)

PHAS:

123828742(CXCR1)

PPAM:

HAI:

RFQ:

PALE:

PGIG:

120587643(CXCR1)

PVP:

105291073

RAY:	107516693(CXCR1)

MJV:

108387357

TOD:	119254843(CXCR1)

LAV:	100653621(CXCR1)

TMU:

101342750

ETF:	101658132(CXCR1)

DNM:	101440815(CXCR1)

MDO:	100012266(CXCR1)

GAS:	123240138(CXCR1)

SHR:

AFZ:

PCW:

TVP:

PBRV:

138151557(CXCR1)

OAA:

100091990

TNG:	GSTEN00016899G001

OTW:

112225298

LRJ:	133344631(ACKR4)

IEL:

PMEO:

RES:

Reference

PMID:1840701

Authors

Holmes WE, Lee J, Kuang WJ, Rice GC, Wood WI

Title

Structure and functional expression of a human interleukin-8 receptor.

Journal

Science 253:1278-80 (1991)
DOI:10.1126/science.1840701

Sequence

[hsa:3577]

Reference

PMID:17197447

Authors

Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW

Title

Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8.

Journal

J Biol Chem 282:11658-66 (2007)
DOI:10.1074/jbc.M607705200

Sequence

[mmu:227288]

LinkDB

DBGET integrated database retrieval system