KEGG ORTHOLOGY: K04188

ORTHOLOGY: K04188

Entry

K04188                      KO

Symbol

CXCR3, GPR9, CD183

Name

C-X-C chemokine receptor type 3

Pathway

map04060

Cytokine-cytokine receptor interaction

map04061

Viral protein interaction with cytokine and cytokine receptor

map04062

Chemokine signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
   04050 Cytokine receptors
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
   04090 CD molecules
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Chemokine
   CXC Chemokine
    K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
Cytokine receptors [BR:ko04050]
Chemokine receptors
  CXC Chemokine
   K04188  CXCR3, GPR9, CD183; C-X-C chemokine receptor type 3
CD molecules [BR:ko04090]
Proteins
  K04188  CD183, CXCR3; chemokine (C-X-C motif) receptor 3

Other DBs

GO:

0016494

Genes

HSA:	2833(CXCR3)

PTR:	465704(CXCR3)

PPS:	100988596(CXCR3)

GGO:	101141174(CXCR3)

PON:	100460370(CXCR3)

PPYG:

129023911(CXCR3)

NLE:	100589040(CXCR3)

HMH:	116811783(CXCR3)

SSYN:

129475619(CXCR3)

MCC:	699438(CXCR3)

MCF:	102124316(CXCR3)

MTHB:

126946237

MNI:	105476639(CXCR3)

CSAB:

103232166(CXCR3)

CATY:

105586110(CXCR3)

PANU:

101013600(CXCR3)

TGE:	112615847(CXCR3)

MLEU:

105548171(CXCR3)

RRO:	104664906(CXCR3)

RBB:	108523893(CXCR3)

TFN:	117077581(CXCR3)

PTEH:

111535674(CXCR3)

CANG:

105512601(CXCR3)

CJC:	100392178(CXCR3)

SBQ:	101046718(CXCR3)

CIMI:

108294796(CXCR3)

ANAN:

105705663(CXCR3)

CSYR:

103273482(CXCR3)

MMUR:

105855307(CXCR3)

LCAT:

123628732(CXCR3)

PCOQ:

105809543(CXCR3)

OGA:	100946272(CXCR3)

MMU:	12766(Cxcr3)

MCAL:

110287394(Cxcr3)

MPAH:

110314183(Cxcr3)

RNO:	84475(Cxcr3)

MCOC:

116093817(Cxcr3)

ANU:	117695326(Cxcr3)

ASYL:

127675190(Cxcr3)

MUN:	110542361 132646017

CGE:	100769241(Cxcr3)

MAUA:

101828396(Cxcr3)

PROB:

127218147(Cxcr3)

PLEU:

114708644(Cxcr3)

MORG:

121442835 121444939

MFOT:

126487042

AAMP:

119805089(Cxcr3)

NGI:	108490059(Cxcr3)

HGL:	101722797(Cxcr3)

CPOC:

100735932(Cxcr3)

DORD:

105997274(Cxcr3)

DSP:	122120658(Cxcr3)

PLOP:

125343403(Cxcr3)

NCAR:

124972346

MMMA:

107155668(Cxcr3)

ITI:	101955160(Cxcr3)

OCU:

100349863

OPI:	101527167(CXCR3)

TUP:	102480904(CXCR3)

GVR:	103606471(CXCR3)

CFA:	491952(CXCR3)

CLUD:

112671832(CXCR3)

VVP:	112907626(CXCR3)

VLG:	121483168(CXCR3)

NPO:	129517934(CXCR3)

AML:	100475682(CXCR3)

UMR:	121102893(CXCR3)

UAH:	113245589(CXCR3)

UAR:	123786513(CXCR3)

ELK:

111161027

LLV:

125092438

MPUF:

101687132(CXCR3)

MNP:	132006814(CXCR3)

MLK:	131821819(CXCR3)

NVS:	122897187(CXCR3)

ORO:	101384395(CXCR3)

EJU:	114202316(CXCR3)

ZCA:	113931052(CXCR3)

MLX:	118025930(CXCR3)

NSU:	110571643(CXCR3)

LWW:	102732960(CXCR3)

FCA:	101094573(CXCR3)

PYU:	121025282(CXCR3)

PCOO:

112870777(CXCR3)

PBG:	122477459(CXCR3)

PVIV:

125157326(CXCR3)

LRUF:

124521604

LGF:	123594883(CXCR3)

AJU:

113597471

PTG:	102968292(CXCR3)

PPAD:

109254623(CXCR3)

PUC:

125931746

HHV:	120246048(CXCR3)

BTA:	497018(CXCR3)

BOM:	102286399(CXCR3)

BIU:	109555556(CXCR3)

BBUB:

102398115(CXCR3)

BBIS:

104986704(CXCR3)

CHX:	100860874(CXCR3)

OAS:	101107671(CXCR3)

BTAX:

128069533(CXCR3)

CSUM:

138071769(CXCR3)

ODA:	120881988(CXCR3)

CCAD:

122434653(CXCR3)

MREE:

136154295(CXCR3)

OVR:	110130770(CXCR3)

MBEZ:

129563919(CXCR3)

SSC:	100524123(CXCR3)

CFR:	102519586(CXCR3)

CBAI:

105083680(CXCR3)

CDK:	105088001(CXCR3)

VPC:	102543538(CXCR3)

BACU:

102997528(CXCR3)

BMUS:

118888886(CXCR3)

LVE:	103073320(CXCR3)

OOR:	101282664(CXCR3)

LALB:

132513139(CXCR3)

DLE:	111167785(CXCR3)

PCAD:

102980207(CXCR3)

PSIU:

116747485(CXCR3)

PPHC:

136142674(CXCR3)

NASI:

112408888(CXCR3)

ECB:	100056190(CXCR3)

EPZ:	103544116(CXCR3)

EAI:	106828868(CXCR3)

MYB:	102246363(CXCR3)

MYD:	102773669(CXCR3)

MMYO:

118654095(CXCR3)

MLF:	102435170(CXCR3)

MDT:	132225275(CXCR3)

PKL:	118704166(CXCR3)

EFUS:

103300711(CXCR3)

MNA:	107532867(CXCR3)

DRO:	112300020(CXCR3)

SHON:

118994968(CXCR3)

AJM:	119035373(CXCR3)

PDIC:

114504938(CXCR3)

PHAS:

123824321(CXCR3)

MMF:	118636502(CXCR3)

PPAM:

129071081(CXCR3)

HAI:	109385587(CXCR3)

RFQ:	117026661(CXCR3)

PALE:

102891275(CXCR3)

PVP:	105299597(CXCR3)

RAY:	107513907(CXCR3)

MJV:	108405031(CXCR3)

TOD:	119246673(CXCR3)

SARA:

101546688(CXCR3)

SETR:

125998871(CXCR3)

LAV:	100665693(CXCR3)

TMU:

101354345

ETF:	101638132(CXCR3)

DNM:	101420212(CXCR3)

MDO:	100013032(CXCR3) 100018972

GAS:	123256315(CXCR3)

SHR:	100928499(CXCR3)

AFZ:

127542689

PCW:	110201105(CXCR3)

TVP:	118832842(CXCR3)

PBRV:

138141686(CXCR3)

OAA:	107547596(CXCR3)

TACU:

119930007(CXCR3)

ASN:	102386240(CXCR3)

AMJ:	102572279(CXCR3)

PSS:	102456891(CXCR3) 106731970

CMY:	102933996(CXCR3)

CCAY:

125625990 125626065(CXCR3)

DCC:	119847622(CXCR3)

CPIC:

101934961(CXCR3) 101938365

TST:	117888900 117889263(CXCR3)

CABI:

116819089 116819097(CXCR3)

MRV:	120390029 120390121

ACS:	100566266 103281533

ASAO:

132780153 132780526

PVT:	110089443 110089444

SUND:

121915787 121916140

PBI:	103049463 112541710

PMUR:

107291284

CTIG:

120312034(CXCR3)

TSR:

106550714

PCAE:

139321155 139321324

APRI:

131204423(CXCR3) 131204424

PTEX:

113445965 113446061

NSS:	113426425 113426426

VKO:	123025895 123025896

PMUA:

114602142 114603626(CXCR3)

PRAF:

128418288(CXCR3) 128418289

ZVI:	118087291 118087305

HCG:	128332886 128333038(CXCR3)

GJA:	107120157(CXCR3) 107125255

STOW:

125428001 125435521(CXCR3)

EMC:	129342988 129343351(CXCR3)

XLA:	101243548(xcxcra) 108697037 108697989 443669(cxcr3.L)

XTR:	100485636 496477(cxcr3)

NPR:	108790964 108790965

RTEM:

ACAT:

BBUF:

BGAR:

DTC:	141084936 141085449

PWL:	138246700 138246701(CXCR3)

MUO:	115465274 115476599

GSH:	117368870(CXCR3)

DRE:	654692(cxcr3.1) 791973(cxcr3.2) 799527(cxcr3.3)

SRX:	107717413 107717415 107717417 107755594 107755753

SANH:

107671169 107671170 107671173 107700147 107700152 107700153 107700155

SGH:	107551668 107551669 107551671 107551704 107598452 107598453 107598454

CCAR:

109070700 109070701 109071960 109103991 109103992 109103993 109105846(cxcr3.3)

CAUA:

113059968 113059969 113059972 113116394 113116395 113116396 113116397

CGIB:

127974394 127975173 127975174 127975426 128030758 128030759 128031163

PTET:

122360449(cxcr3.3) 122360832 122360950(cxcr3.1) 122361094(cxcr3.2)

LROH:

127178900 127178902 127178903 127178935(cxcr3.2) 127179013(cxcr3.3)

GRF:	141342871(cxcr3.1) 141342961(cxcr3.2) 141342999(cxcr3.3)

OMC:	131521837 131521867(cxcr3.2) 131522428(cxcr3.3) 131522429

PPRM:

120484273(cxcr3.2) 120484557(cxcr3.3) 120484777(cxcr3.1)

RKG:	130103630(cxcr3.3) 130103632(cxcr3.1) 130103646(cxcr3.2)

MAMB:

125242801(cxcr3.2) 125243551 125243664 125243767(cxcr3.3) 125243886(cxcr3.1) 125244150

CIDE:

127497377 127497569 127497636 127497851

CERY:

137025900(cxcr3.3) 137025916(cxcr3.2) 137029206 137032102(cxcr3.1)

MASI:

127453043 127453044 127453279 127453963 127453964

TROS:

130558473(cxcr3.2) 130558474(cxcr3.3) 130558475(cxcr3.1) 130558479

TDW:	130433499(cxcr3.2) 130433502(cxcr3.3) 130433504 130433509

MANU:

129448312 129449114(cxcr3.1) 129449182(cxcr3.2)

PDAB:

135727816(cxcr3.2) 135727820(cxcr3.1) 135743437

IPU:	108266504 108266514(cxcr3.2) 108266523(cxcr3.1)

IFU:	128607989(cxcr3.2) 128607994(cxcr3.1) 128608006(cxcr3.3)

PHYP:

113542415 113542417 113542500

SMEO:

124383901(cxcr3.2) 124384489 124384490(cxcr3.1)

TFD:	113642942 113642947(cxcr3.1) 113643747(cxcr3.2)

TVC:	132846105(cxcr3.3) 132846106(cxcr3.1) 132846107(cxcr3.2)

CGAR:

128519827(cxcr3.2) 128520114(cxcr3.3) 128520115

NGRA:

132885964(cxcr3.2) 132886666(cxcr3.3) 132886667

TRN:	134310089 134310090 134310305(cxcr3.1) 134310307

AMEX:

103025791 103040958(cxcr3.2) 103041274(cxcr3.1)

CMAO:

118814318 118814327 118814672 118824721(cxcr3.2) 118824737

EEE:	113569070 113569342 113583240 113587949

CHAR:

105910630(cxcr3.2) 105910637 116222314(cxcr3.1)

SPIL:

134082952 134082953 134082954 134082957 134082958(cxcr3.2)

TRU:	101079665 101079894 101080123

TFS:	130532994(cxcr3.1) 130533002 130533016(cxcr3.2)

TNG:	GSTEN00015608G001

LCO:	104922270 104922271(cxcr3) 109140398

NCC:	104957387 104957388

TBEN:

117477290 117477293(cxcr3.1)

CGOB:

115021205 115021206(cxcr3) 115021454

PGEO:

117460821(cxcr3.2) 117461226 117461484(cxcr3.1)

GACU:

117549547(cxcr3.2) 117549553 117549597 117549629

EMAC:

134861268(cxcr3.2) 134861276(cxcr3.1) 134861277

ELY:	117265429 117265594(cxcr3.2) 117265683(cxcr3.1)

EFO:	125892566(cxcr3.2) 125893059(cxcr3.1) 125893696

PLEP:

121946046 121946047

SLUC:

116042325 116042340(cxcr3.2) 116042354(cxcr3.1)

ECRA:

117945634(cxcr3.2) 117945635(cxcr3.1) 117945636

ESP:	116691266 116691267 116691268

PFLV:

114557129 114557291 114557679 114570115

GAT:	120810746 120810747 120810748(cxcr3.1)

PPUG:

119197611(cxcr3.2) 119197612(cxcr3.1) 119197616

AFB:	129109473(cxcr3.1) 129109474 129109890(cxcr3.2)

CLUM:

117745181 117745182 117745372(cxcr3.2)

PSWI:

130212661(cxcr3.2) 130212662(cxcr3.1) 130212664

CANA:

137781289(cxcr3.2) 137781290(cxcr3.1) 137781291

CVE:	137874253(cxcr3.2) 137874254(cxcr3.1) 137874256

MSAM:

119897350(cxcr3.2) 119897352 119897353 119898181

SCHU:

122881975 122881976 122881977(cxcr3.2)

CUD:	121513741(cxcr3.2) 121513742(cxcr3.1) 121513743

SPUL:

138583679(cxcr3.2) 138583937(cxcr3.1) 138584097

LMIX:

132983792(cxcr3.1) 132983794 132983795(cxcr3.2)

ALAT:

119006558(cxcr3.2) 119006559(cxcr3.1) 119006561

ASTR:

137601565 137602078(cxcr3.2) 137602079

MZE:	101464217 101481446 101481928 105940418 105940902 106675620 106675624 111501006

ONL:	100701965 100702230 100702497 100702768 100709758 102076104 109204161 109204162 112841684

OAU:	116309489 116309497 116309502(cxcr3.2) 116309503 116309504 116309506 116309523 116309524 116309525

OLA:	101155297 101155542 101155796 101156279

OML:	112143683(cxcr3.1) 112143687(cxcr3.2) 112143689

CSAI:

133436090 133436117(cxcr3.1) 133441067(cxcr3.2)

XMA:	102217699 102217954 102218214 102235421 106699907

XCO:	114141553 114141554 114141556 114141557 114142320

XHE:	116717029 116717370 116717371 116717729 116717730

PRET:

103477921 103477922 103477924 103477925 103477927

PFOR:

103139220 103139221 103139223 103139224 103139225

PLAI:

106959961 106959970 106959975 106959985 106960000

PMEI:

106916829 106916831 106916832 106916833 106916834

GAF:	122831133(cxcr3.1) 122831134 122831251(cxcr3.2) 122831254

PPRL:

129371364(cxcr3.2) 129371365 129371366 129371369

CVG:	107100210 107100215 107100216 107100217 107100220

CTUL:

119782996 119783085(cxcr3.2) 119783112 119783134(cxcr3.1) 119783160

GMU:	124862597 124862607 124865340 124865847(cxcr3.2) 124866136 124866178 124866179

NFU:	107379529 107379530 107379544

KMR:	108235339 108235340 108235357(cxcr3.2) 108235481

ALIM:

106526017 106526018 106526041

NWH:	119409682 119409683 119409684(cxcr3.2) 119409687

AOCE:

111562955(cxcr3.1) 111562956(cxcr3.2) 111562957

EJA:	138194012(cxcr3.1) 138194013 138194015(cxcr3.2)

BFRE:

138623934(cxcr3.2) 138624043(cxcr3.1) 138624044

MCEP:

125015708(cxcr3.2) 125015796 125016354 125016355

CSEM:

103388808(cxcr3) 103388851 103399412 107988052

POV:	109633295(cxcr3) 109633299 109633303

SSEN:

122774172(cxcr3.2) 122774258(cxcr3.1) 122775303

SSOE:

131470873(cxcr3.1) 131471454(cxcr3.2) 131471960

HHIP:

117776612(cxcr3.1) 117776613 117776614(cxcr3.2)

HSP:	118113116 118113118(cxcr3.1) 118114149(cxcr3.2)

PPLT:

128448807(cxcr3.1) 128448808(cxcr3.2) 128448809

SMAU:

118303843(cxcr3.2) 118303859 118311154(cxcr3.1)

LCF:	108880697(cxcr3.1) 108880701 127138912

SDU:	111236054 111236055 111236056

SLAL:

111653763 111657254 111657258 111657259

XGL:	120783599(cxcr3.2) 120784648 120784734(cxcr3.1)

HCQ:	109531693 109531694 109531706

SSCV:

125975757(cxcr3.2) 125975758(cxcr3.1) 125975762(cxcr3.3)

SBIA:

133500266(cxcr3.1) 133500267 133500369(cxcr3.2)

PEE:	133401372 133401373(cxcr3.2) 133402062(cxcr3.1)

PTAO:

133479862 133480095(cxcr3.2) 133480143(cxcr3.1)

BPEC:

110174310 110174337 110174346

ENY:	140374318(cxcr3.2) 140374409 140374445(cxcr3.1)

MALB:

109954611 109954670

BSPL:

114843492(cxcr3.1) 114843493 114843674(cxcr3.2)

SJO:	128366160 128366248(cxcr3.2) 128366257(cxcr3.1)

SSCO:

133983520(cxcr3.1) 133983567(cxcr3.2) 133984034

GMH:	115554287 115554288(cxcr3) 115554314

SASA:

100195464(cxcr3) 106578794 106578808 106578934 106605553 106605554 106605567

STRU:

115176854 115176855 115177239 115183745 115183760 115183809 115183855

OTW:	112226311 112226320 112235048 112235049 112235050 112235051

OMY:	100136126(cxcr3.1) 100136649(cxcr3.2) 110514317 110537622 110537629

OGO:	123996825(cxcr3.1) 123998070 123998071 123998072 124005854 124030774

ONE:	115101398 115101423 115114369 115118469 115118471 115118478 115118479

OKI:	109878895 109878896 109878898 109878899 109906536

OKE:	118366561 118366562(cxcr3.2) 118367869 118371286 118371289 118371290

OMM:	135520541(cxcr3.1) 135520542 135520543 135521954 135521955 135523062

OCLA:

139379846 139379862 139395898 139395899 139396842 139396844 139405778 139405779 139405780 139417527 139419207

SALP:

111958713 111958755 111959034 111964850 111964851 111964852

SNH:	120047289 120047701 120047703 120047751 120047752(cxcr3.2) 120048664 120048665 120048666

CCLU:

121542866 121542867 121585487 121585488 121585489

ELS:	105008351 105024269 105024306(cxcr3)

OEP:	134023482(cxcr3.1) 134023483(cxcr3.2) 134023485

SFM:	108922204 108922206 108922209 108922237

PKI:	111853595 111854813 111854816 111854837

AANG:

118214368(cxcr3.1) 118219811 118221258(cxcr3.2) 118232871

AROT:

135234302(cxcr3.2) 135234309(cxcr3.1) 135234324 135261937

CCOG:

133118164(cxcr3.2) 133134322(cxcr3.1) 133136408 133139390

LOC:

102682204

PSPA:

121298892 121298906 121299368 121304154 121304228 121304238

ARUT:

117433765 117433925 117433930 117964873 117964908 117964909 117969114 117969115

LCM:	102350639 102366874 106703416

RTP:	109922738 109925403 109925415

CPLA:

122540094 122544216 122544217 122548282

HOC:	132833564 132833983 132833996

LERI:

HAKA:

PMRN:

LRJ:

ATEN:

Reference

PMID:9064356

Authors

Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B

Title

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes.

Journal

J Exp Med 184:963-9 (1996)
DOI:10.1084/jem.184.3.963

Sequence

[hsa:2833]

Reference

PMID:12782716

Authors

Lasagni L, Francalanci M, Annunziato F, Lazzeri E, Giannini S, Cosmi L, Sagrinati C, Mazzinghi B, Orlando C, Maggi E, Marra F, Romagnani S, Serio M, Romagnani P

Title

An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4.

Journal

J Exp Med 197:1537-49 (2003)
DOI:10.1084/jem.20021897

Sequence

[hsa:2833]

LinkDB

DBGET integrated database retrieval system