KEGG ORTHOLOGY: K04259

ORTHOLOGY: K04259

Entry

K04259                      KO

Symbol

PTGER2

Name

prostaglandin E receptor 2

Pathway

map04024

cAMP signaling pathway

map04080

Neuroactive ligand-receptor interaction

map04148

Efferocytosis

map04750

Inflammatory mediator regulation of TRP channels

map04924

Renin secretion

map05163

Human cytomegalovirus infection

map05200

Pathways in cancer

Disease

H01191

Asthma with nasal polyps and aspirin intolerance

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K04259  PTGER2; prostaglandin E receptor 2
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04259  PTGER2; prostaglandin E receptor 2
09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K04259  PTGER2; prostaglandin E receptor 2
09150 Organismal Systems
  09152 Endocrine system
   04924 Renin secretion
    K04259  PTGER2; prostaglandin E receptor 2
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04259  PTGER2; prostaglandin E receptor 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04259  PTGER2; prostaglandin E receptor 2
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K04259  PTGER2; prostaglandin E receptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04259  PTGER2; prostaglandin E receptor 2
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Lipid
   Prostaglandin
    K04259  PTGER2; prostaglandin E receptor 2

Other DBs

GO:

0004957

Genes

HSA:	5732(PTGER2)

PTR:	467459(PTGER2)

PPS:	100969154(PTGER2)

GGO:	101150673(PTGER2)

PON:	100440992(PTGER2)

PPYG:

129012709(PTGER2)

NLE:	100581272(PTGER2)

HMH:	116485006(PTGER2)

SSYN:

129487894(PTGER2)

MCC:	708024(PTGER2)

MCF:	102121812(PTGER2)

MTHB:

126958526

MNI:	105481819(PTGER2)

CSAB:

103228990(PTGER2)

CATY:

105586619(PTGER2)

PANU:

101014300(PTGER2)

TGE:	112628904(PTGER2)

MLEU:

105553603(PTGER2)

RRO:	104669170(PTGER2)

RBB:	108513697(PTGER2)

TFN:	117069645(PTGER2)

PTEH:

111549502(PTGER2)

CANG:

105525973(PTGER2)

CJC:	100394168(PTGER2)

SBQ:	101043873(PTGER2)

CIMI:

108291932(PTGER2)

ANAN:

105716423(PTGER2)

MMUR:

105867692(PTGER2)

LCAT:

123649164(PTGER2)

PCOQ:

105825872(PTGER2)

OGA:	100965094(PTGER2)

MMU:	19217(Ptger2)

MCAL:

110309863(Ptger2)

MPAH:

110325898(Ptger2)

RNO:	81752(Ptger2)

MCOC:

116084940(Ptger2)

ANU:	117705736(Ptger2)

ASYL:

127691702(Ptger2)

MUN:	110563956(Ptger2)

CGE:	100774710(Ptger2)

MAUA:

101826580(Ptger2)

PROB:

127214567(Ptger2)

PLEU:

114696004(Ptger2)

MORG:

121435087(Ptger2)

MFOT:

126513862

AAMP:

119800205(Ptger2)

NGI:	103739242(Ptger2)

HGL:	101718143(Ptger2)

CPOC:

100730468(Ptger2)

CCAN:

109683947(Ptger2)

DORD:

105982609(Ptger2)

DSP:	122106498(Ptger2)

PLOP:

125363313(Ptger2)

NCAR:

124978009

MMMA:

107138275(Ptger2)

ITI:	101974140(Ptger2)

OCU:	100009369(PTGER2)

OPI:	101529940(PTGER2)

TUP:	102492232(PTGER2)

GVR:	103596816(PTGER2)

CFA:	403797(PTGER2)

CLUD:

112657518(PTGER2)

VVP:	112921431(PTGER2)

VLG:	121493937(PTGER2)

NPO:	129496219(PTGER2)

AML:	100479883(PTGER2)

UMR:	103672874(PTGER2)

UAH:	113242376(PTGER2)

UAR:	123800669(PTGER2)

ELK:

111140622

LLV:

125105352

MPUF:

101688109(PTGER2)

MNP:	131999946(PTGER2)

MLK:	131836566(PTGER2)

NVS:	122893685(PTGER2)

ORO:	101379988(PTGER2)

EJU:	114208052(PTGER2)

ZCA:	113910179(PTGER2)

MLX:	118002170(PTGER2)

NSU:	110590674(PTGER2)

LWW:	102734368(PTGER2)

FCA:	100169967(PTGER2)

PYU:	121031765(PTGER2)

PCOO:

112856234(PTGER2)

PBG:	122469091(PTGER2)

PVIV:

125168190(PTGER2)

LRUF:

124512192

LGF:	123583834(PTGER2)

AJU:

106981938

PTG:	102953086(PTGER2)

PPAD:

109268475(PTGER2)

PUC:

125909501

PLEZ:

122222705(PTGER2)

HHV:	120226875(PTGER2)

BTA:	282329(PTGER2)

BOM:	102286394(PTGER2)

BIU:	109564679(PTGER2)

BBUB:

102411238(PTGER2)

BBIS:

104984701(PTGER2)

CHX:	102181502(PTGER2)

OAS:	443013(PTGER2)

BTAX:

128054611(PTGER2)

CSUM:

138074474(PTGER2)

ODA:	120852556(PTGER2)

CCAD:

122443032(PTGER2)

MREE:

136171756(PTGER2)

OVR:	110137205(PTGER2)

MBEZ:

129563200(PTGER2)

SSC:	100127164(PTGER2)

CFR:	102511634(PTGER2)

CBAI:

105074575(PTGER2)

CDK:	105091422(PTGER2)

VPC:	102532574(PTGER2)

BACU:

103006174(PTGER2)

BMUS:

118890549(PTGER2)

LVE:	103069314(PTGER2)

OOR:	101282504(PTGER2)

LALB:

132516193(PTGER2)

DLE:	111173156(PTGER2)

PCAD:

102984254(PTGER2)

PSIU:

116749424(PTGER2)

NASI:

112392874(PTGER2)

ECB:	100067279(PTGER2) 111769596

EPZ:	103564708(PTGER2)

EAI:	106839484(PTGER2)

MYB:	102261194(PTGER2)

MYD:	102771588(PTGER2)

MMYO:

118655337(PTGER2)

MLF:	102442700(PTGER2)

MDT:	132234704(PTGER2)

MYUM:

139013571(PTGER2)

PKL:	118718166(PTGER2)

EFUS:

103283743(PTGER2)

MNA:	107525947(PTGER2)

DRO:	112311151(PTGER2)

SHON:

118992398(PTGER2)

AJM:	119057016(PTGER2)

PDIC:

114492781(PTGER2)

PHAS:

123808766(PTGER2)

MMF:	118637135(PTGER2)

PPAM:

129065781(PTGER2)

HAI:	109384486(PTGER2)

RFQ:	117024228(PTGER2)

PALE:

102884861(PTGER2)

PGIG:

120604427(PTGER2)

PVP:	105309351(PTGER2)

RAY:	107498129(PTGER2)

MJV:	108396416(PTGER2)

TOD:	119239091(PTGER2)

SARA:

101553999(PTGER2)

SFUM:

130041621(PTGER2)

SETR:

125999384(PTGER2)

LAV:	100675931(PTGER2)

TMU:

101353619

ETF:	101650497(PTGER2)

DNM:	101410978(PTGER2)

MDO:	100015803(PTGER2)

GAS:	123235725(PTGER2)

PCW:	110199890(PTGER2)

TVP:	118840973(PTGER2)

PBRV:

138156794(PTGER2)

OAA:	100085048(PTGER2)

TACU:

119937245(PTGER2)

GGA:	100034745(PTGER2)

PCOC:

116234627(PTGER2)

MGP:	100543250(PTGER2)

CJO:

107315535

TPAI:

128087226(PTGER2)

LMUT:

125695102(PTGER2)

NMEL:

110401618

ACYG:

106044017

CATA:

118250341(PTGER2)

AFUL:

116489973(PTGER2)

TGU:	100226783(PTGER2)

LSR:	110474759(PTGER2)

SCAN:

103826835

PMOA:

120500706(PTGER2)

OTC:	121338866(PTGER2)

PRUF:

121348700(PTGER2)

ATRC:

139589620(PTGER2)

GFR:	102031653(PTGER2)

FAB:	101813687(PTGER2)

OMA:	130253781(PTGER2)

PHI:	102103262(PTGER2)

PMAJ:

107205388(PTGER2)

CCAE:

111929655

CCW:	104695903(PTGER2)

CBRC:

103618899(PTGER2)

ACOE:

138110935

ETL:	114068794(PTGER2)

ZLE:	135448552(PTGER2)

ACHL:

103798916(PTGER2)

SVG:	106850285(PTGER2)

MMEA:

130585684(PTGER2)

HRT:	120754384(PTGER2)

SATI:

136362732(PTGER2)

CCIC:

134045498(PTGER2)

FPG:	101913795(PTGER2)

FCH:	102052257(PTGER2)

SHAB:

115607495(PTGER2)

ACUN:

113480399(PTGER2)

TALA:

116965630(PTGER2)

ACHC:

115353325(PTGER2)

HLE:	104839475(PTGER2)

AGEN:

126050607

HHAR:

128140132(PTGER2)

GCL:

127016875

LDI:

104348078

DPUB:

104299380(PTGER2)

PPUS:

135180226(PTGER2)

AVIT:

104270181(PTGER2)

BRHI:

104498761(PTGER2)

EGZ:	104129557(PTGER2)

NNI:	104019481(PTGER2)

PCAO:

104052540

PADL:

103916009

AFOR:

103907674

FGA:	104072622(PTGER2)

CLV:	102094237(PTGER2)

MUI:

104543162

PGUU:

104467590(PTGER2)

CUCA:

104057464(PTGER2)

TEO:

104371493

ACAR:

104522486(PTGER2)

CPEA:

104394622

CVF:	104294350(PTGER2)

RTD:	128908717(PTGER2)

CRID:

134514625(PTGER2)

AAM:

106490258

AROW:

112961179(PTGER2)

NPD:

112957756

TGT:

104570529

DNE:	112988539(PTGER2)

SCAM:

104145562

AMJ:	102570254(PTGER2)

CMY:	102934214(PTGER2)

CCAY:

125637563(PTGER2)

DCC:	119857874(PTGER2)

CPIC:

101935065(PTGER2)

TST:	117877094(PTGER2)

CABI:

116816603(PTGER2)

MRV:	120402921(PTGER2)

ACS:

100565412

ASAO:

132762176(PTGER2)

SUND:

121927244(PTGER2)

PBI:	103057692(PTGER2)

PMUR:

107302012

CTIG:

120297794(PTGER2)

TSR:

106537824

PGUT:

117675069(PTGER2)

APRI:

131188084(PTGER2)

PTEX:

113434906(PTGER2)

NSS:	113414105(PTGER2)

PMUA:

114594491(PTGER2)

PRAF:

128401995(PTGER2)

ZVI:	118076958(PTGER2)

HCG:	128339416(PTGER2)

GJA:	107118955(PTGER2)

EMC:	129324605(PTGER2)

XLA:	108698769(ptger2.L) 403391(ptger2.S)

XTR:	100493226(ptger2)

NPR:

108788581

RTEM:

120920153(PTGER2)

BBUF:

120981601(PTGER2)

BGAR:

122922171(PTGER2) 122924954

MUO:

115478135

GSH:

117364275

DRE:	393608(ptger2a) 570410(ptger2b)

SRX:	107712417 107723575 107729076 107751768

SANH:

107664800 107679983 107693138 107695977

SGH:	107549539 107564990 107577305 107583455

CCAR:

109077567(ptger2b) 109103315

CAUA:

113037961 113060757 113060774 113062998 113069485 113121188

CGIB:

127939063 127976808 127983362 128031430

PTET:

122324285(ptger2b) 122362082(ptger2a)

LROH:

127179265(ptger2a) 127183269(ptger2b)

OMC:	131522715(ptger2a) 131526657(ptger2b)

PPRM:

120479644(ptger2a) 120494194(ptger2b)

RKG:	130096063(ptger2b) 130101494(ptger2a)

MAMB:

125268462(ptger2a) 125279019(ptger2b)

CIDE:

127498552 127501813

CERY:

137006552(ptger2a) 137018717(ptger2b)

MASI:

127410142 127411196 127416247 127455307

TROS:

130560646(ptger2a)

TDW:	130437284(ptger2a)

MANU:

129417946(ptger2a)

PDAB:

135727067 135734195

IPU:	108257678(ptger2b) 108269911(ptger2a)

IFU:	128601185(ptger2b) 128612805(ptger2a)

PHYP:

113525041 113533911

SMEO:

124377104(ptger2b) 124389770(ptger2a)

TFD:	113639969(ptger2b) 113651224(ptger2a)

TVC:	132842974(ptger2b) 132852914(ptger2a)

CGAR:

128514764(ptger2b) 128536193(ptger2a)

NGRA:

132883058(ptger2b) 132894180(ptger2a)

TRN:	134320187(ptger2b) 134325199(ptger2a)

AMEX:

103029411(ptger2b) 103035710(ptger2a)

CMAO:

118815961(ptger2b) 118823300(ptger2a)

EEE:	113571081(ptger2)

CHAR:

105895421(ptger2a) 105901390

SPIL:

134068083(ptger2a) 134097821 134097822

TRU:

101075152

TFS:	130522808(ptger2a)

TNG:	GSTEN00019596G001

LCO:	104929889 104938523

NCC:	104961803 104962050

TBEN:

117498464 117498989(ptger2a)

CGOB:

115003713 115016879

PGEO:

117440387(ptger2b) 117458212(ptger2a)

GACU:

117532379(ptger2b) 117546732(ptger2a)

EMAC:

134860780(ptger2a) 134877246(ptger2b)

ELY:	117250214(ptger2a) 117271059

EFO:	125884917(ptger2a) 125897400

PLEP:

121963025(ptger2a) 121963415

SLUC:

116044593(ptger2a)

ECRA:

117939292(ptger2a)

ESP:	116673836(ptger2)

PFLV:

114550793(ptger2)

GAT:	120816391(ptger2a)

PPUG:

119217393(ptger2a)

AFB:	129111731(ptger2a)

CLUM:

117745433(ptger2a)

PSWI:

130204490(ptger2a)

CANA:

137794236(ptger2a)

CVE:	137879147(ptger2a)

MSAM:

119901701(ptger2a)

SCHU:

122872255(ptger2a)

CUD:	121506411(ptger2a)

SPUL:

138603761(ptger2a)

LMIX:

132959614(ptger2a)

ALAT:

119015352(ptger2a)

ASTR:

137591133(ptger2a)

MZE:

101463917

ONL:

100703512

OAU:	116321024(ptger2a)

OLA:

101174008

OML:	112160198(ptger2a)

CSAI:

133424923(ptger2a)

XMA:	102227642(ptger2)

XCO:	114140994(ptger2)

XHE:	116715921 116716168(ptger2)

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122827308(ptger2a)

PPRL:

129379025(ptger2a)

CVG:	107086911(ptger2)

CTUL:

119790379(ptger2a)

GMU:	124861717(ptger2a)

NFU:

107381029

KMR:	108248505(ptger2a)

ALIM:

106519163(ptger2)

NWH:	119429020(ptger2a)

AOCE:

111566530(ptger2a)

EJA:	138208515(ptger2a)

BFRE:

138629213(ptger2a)

MCEP:

125000805(ptger2a)

CSEM:

103389770(ptger2)

POV:	109632432 109640537

SSEN:

122784000(ptger2b) 122784331(ptger2a)

SSOE:

131443681 131475464(ptger2a)

HHIP:

117758835(ptger2b) 117774775(ptger2a)

HSP:	118099553(ptger2b) 118103257(ptger2a)

PPLT:

128430789(ptger2a) 128460497(ptger2b)

SMAU:

118302398(ptger2a)

LCF:	108900625(ptger2a) 108901740(ptger2b)

SDU:	111222684 111236052

SLAL:

111646041 111667910

XGL:	120788594(ptger2b) 120798295(ptger2a)

HCQ:	109510344(ptger2)

SSCV:

125988356(ptger2a)

SBIA:

133509814(ptger2a)

PEE:	133406106(ptger2a)

PTAO:

133483954(ptger2a)

BPEC:

110153267(ptger2)

ENY:	140377410(ptger2a)

MALB:

109955798

BSPL:

114850065 114850796(ptger2a)

SJO:	128354069(ptger2a)

SSCO:

133976503(ptger2a)

GMH:	115534469 115542897(ptger2)

SASA:

106571730 106602991 106608165 106610617

STRU:

115161145 115172194 115174591

OTW:	112217917 112251755 112256413 112261470

OMY:	110497541 110505223(ptger2a) 110522542 110529782

OGO:	123991665 123995723 124001151 124045197(ptger2a)

ONE:	115107332 115123969 115138246 115145874

OKI:	109866514 109882855 109900292 109903827

OKE:	118362798 118368578(ptger2a) 118387115 118398490

OMM:	135505541 135507843 135526127(ptger2a) 135557893

OCLA:

139374170 139383718 139407873 139415637

SALP:

111954183 111968407 111972480 112068208

SNH:	120019155 120023836(ptger2a) 120024433 120059962

CCLU:

121539647 121545172 121549216 121552834(ptger2b)

ELS:	105017572 105023270

OEP:	134007744(ptger2a) 134025155

SFM:	108919494(ptger2) 108924037

PKI:	111840261 111859947

AANG:

AROT:

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

120518828(ptger2a)

LCM:	102345258(PTGER2)

RTP:	109932748(ptger2a)

CPLA:

HOC:

LERI:

HRF:

HCRA:

CANU:

CVN:

XEN:

Reference

PMID:8078484

Authors

Regan JW, Bailey TJ, Pepperl DJ, Pierce KL, Bogardus AM, Donello JE, Fairbairn CE, Kedzie KM, Woodward DF, Gil DW

Title

Cloning of a novel human prostaglandin receptor with characteristics of the pharmacologically defined EP2 subtype.

Journal

Mol Pharmacol 46:213-20 (1994)

Sequence

[hsa:5732]

LinkDB

DBGET integrated database retrieval system