KEGG   ORTHOLOGY: K04289
Entry
K04289                      KO                                     

Symbol
LPAR1, EDG2
Name
lysophosphatidic acid receptor 1
Pathway
map04015  Rap1 signaling pathway
map04072  Phospholipase D signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04151  PI3K-Akt signaling pathway
map04540  Gap junction
map04810  Regulation of actin cytoskeleton
map05130  Pathogenic Escherichia coli infection
map05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
   04072 Phospholipase D signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
   04151 PI3K-Akt signaling pathway
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Lipid
   Lysophosphatidic acid
    K04289  LPAR1, EDG2; lysophosphatidic acid receptor 1
Other DBs
GO: 0070915
Genes
HSA: 1902(LPAR1)
PTR: 464655(LPAR1)
PPS: 100981266(LPAR1)
GGO: 101144872(LPAR1)
PON: 100458931(LPAR1)
NLE: 100589911(LPAR1)
MCC: 709208(LPAR1)
MCF: 101864894(LPAR1) 102125640
CSAB: 103219021(LPAR1)
CATY: 105595544(LPAR1)
PANU: 101008582(LPAR1)
RRO: 104664137(LPAR1)
RBB: 108513979
TFN: 117080883 117098844(LPAR1)
PTEH: 111535768(LPAR1)
CJC: 100414340(LPAR1)
SBQ: 101035023(LPAR1)
MMUR: 105855669(LPAR1)
MMU: 14745(Lpar1)
MCAL: 110292580(Lpar1)
MPAH: 110322872(Lpar1)
RNO: 116744(Lpar1)
MCOC: 116096072(Lpar1)
MUN: 110554214(Lpar1)
CGE: 100757522(Lpar1)
PLEU: 114683458(Lpar1)
NGI: 103732526(Lpar1)
HGL: 101713333(Lpar1)
CCAN: 109692877(Lpar1)
OCU: 100355169(LPAR1)
OPI: 101531567(LPAR1)
TUP: 102503029(LPAR1)
CFA: 474800(LPAR1)
VVP: 112923052(LPAR1)
VLG: 121495881(LPAR1)
AML: 100479569(LPAR1)
UMR: 103678568(LPAR1)
UAH: 113260324(LPAR1)
ORO: 101371767(LPAR1)
ELK: 111145805
MPUF: 101670591(LPAR1)
EJU: 114213525(LPAR1)
MLX: 118017823(LPAR1)
FCA: 101092556(LPAR1)
PYU: 121034828(LPAR1)
PBG: 122474974(LPAR1)
PTG: 102968521(LPAR1)
PPAD: 109269980(LPAR1)
AJU: 106971772(LPAR1)
HHV: 120237558(LPAR1)
BTA: 281136(LPAR1)
BOM: 102273019(LPAR1)
BIU: 109563336(LPAR1) 109563337
BBUB: 102406108(LPAR1)
CHX: 102189399(LPAR1)
OAS: 443346(LPAR1)
ODA: 120862540(LPAR1)
CCAD: 122432004(LPAR1)
SSC: 100512581(LPAR1)
CFR: 102522277(LPAR1)
CBAI: 105080960(LPAR1)
CDK: 105096434
BACU: 103015300(LPAR1)
LVE: 103091078(LPAR1)
OOR: 101274338(LPAR1)
DLE: 111177336(LPAR1)
PCAD: 102992144(LPAR1)
ECB: 100053797(LPAR1)
EPZ: 103546686(LPAR1)
EAI: 106826903(LPAR1)
MYB: 102258769(LPAR1)
MYD: 102762844(LPAR1)
MMYO: 118667192(LPAR1)
MNA: 107537650(LPAR1)
PKL: 118716174(LPAR1)
HAI: 109379349(LPAR1)
DRO: 112304468(LPAR1)
SHON: 118979710(LPAR1)
AJM: 119054717(LPAR1)
MMF: 118629489(LPAR1)
PALE: 102891503(LPAR1)
PGIG: 120608747(LPAR1)
RAY: 107502626(LPAR1)
MJV: 108408598(LPAR1)
TOD: 119232591(LPAR1)
LAV: 100668056(LPAR1)
TMU: 101344103
MDO: 100016607(LPAR1) 103103209
GAS: 123233099(LPAR1) 123246116
SHR: 100928953(LPAR1) 100932534
OAA: 100077696(LPAR1)
GGA: 427339(LPAR1)
PCOC: 116227856 116238581(LPAR1)
MGP: 100541536(LPAR1) 109363681
CJO: 107306591(LPAR1)
NMEL: 110389432(LPAR1) 110407913
APLA: 101796868 101802482(LPAR1)
ACYG: 106043035(LPAR1) 106046837
TGU: 100223722(LPAR1) 115497772
LSR: 110467706 110467746(LPAR1)
SCAN: 103820340 103821825(LPAR1)
PMOA: 120507715 120513665(LPAR1)
OTC: 121333657(LPAR1) 121347092
PRUF: 121361647 121363732(LPAR1)
GFR: 102032612 102038748(LPAR1)
FAB: 101814928 101819651(LPAR1)
PHI: 102105561 102111782(LPAR1)
PMAJ: 107198333(LPAR1) 107212973
CCAE: 111937972 111941320(LPAR1)
CCW: 104690481(LPAR1) 104690993
ETL: 114069483 114072958(LPAR1)
FPG: 101920309(LPAR1) 106112258
FCH: 102050804 102058846(LPAR1)
CLV: 102084885(LPAR1) 102089623
EGZ: 104121830 104123052(LPAR1)
NNI: 104017012 104019835(LPAR1)
ACUN: 113487191 113490290(LPAR1)
PADL: 103917222 103921055(LPAR1)
AAM: 106494707 106499585(LPAR1)
AROW: 112964001(LPAR1) 112968785
NPD: 112948525(LPAR1) 112954726
DNE: 112993355(LPAR1)
ASN: 102382491(LPAR1) 112551204
AMJ: 102563758(LPAR1)
CPOO: 109323482(LPAR1)
GGN: 109297344(LPAR1)
PSS: 102445645(LPAR1) 102453320
CMY: 102935396(LPAR1)
CPIC: 101932155(LPAR1)
TST: 117867668
CABI: 116816034(LPAR1) 116824200
ACS: 100565601(lpar1)
PVT: 110075502 110077739(LPAR1)
PBI: 103053763(LPAR1) 103055321
TSR: 106544059(LPAR1) 106555676
VKO: 123022172(LPAR1)
PMUA: 114585716 114587543(LPAR1)
ZVI: 118097241 118097715(LPAR1)
GJA: 107108929 107114523(LPAR1)
XLA: 373591(lpar1.L) 379403(lpar1.S)
XTR: 100124893(lpar1) 116408597
NPR: 108787629(LPAR1)
DRE: 368461(lpar1)
SANH: 107653498(lpar1)
IPU: 108277333(lpar1)
PHYP: 113544013
EEE: 113577615(lpar1)
TRU: 101075588
LCO: 104927704(lpar1)
NCC: 104964645(lpar1)
CGOB: 115016765(lpar1)
ELY: 117269622(lpar1)
PLEP: 121959575(lpar1)
SLUC: 116045146(lpar1)
ECRA: 117959349(lpar1)
PFLV: 114570530(lpar1)
GAT: 120831908(lpar1)
PPUG: 119226920(lpar1)
MSAM: 119914404(lpar1)
CUD: 121525053(lpar1)
MZE: 101487294(lpar1)
ONL: 100691976(lpar1)
OAU: 116330842(lpar1)
OLA: 101164735(lpar1)
OML: 112163332(lpar1)
XMA: 102222146(lpar1)
XCO: 114149710(lpar1)
XHE: 116724406(lpar1)
PRET: 103473989(lpar1)
CVG: 107091062(lpar1)
CTUL: 119772071(lpar1)
NFU: 107396668(lpar1)
KMR: 108232758(lpar1)
ALIM: 106513587(lpar1)
AOCE: 111581611(lpar1)
CSEM: 103390307(lpar1) 103399363
POV: 109646242(lpar1)
LCF: 108880309(lpar1)
SDU: 111237500
SLAL: 111655943
XGL: 120806521(lpar1)
HCQ: 109530147(lpar1)
BPEC: 110166379
MALB: 109960839(lpar1)
OMY: 110523108(lpar1) 110536854
SNH: 120041108(lpar1) 120043038
ELS: 105026669
SFM: 108936306
PKI: 111842175
LOC: 102692058(lpar1)
ARUT: 117408648(lpar1) 117420893
LCM: 102349282(LPAR1)
CMK: 103187154(lpar1)
RTP: 109929476
CIN: 100182538
ATEN: 116289414
ADF: 107357274
 » show all
Reference
PMID:9070858
  Authors
An S, Dickens MA, Bleu T, Hallmark OG, Goetzl EJ
  Title
Molecular cloning of the human Edg2 protein and its identification as a functional cellular receptor for lysophosphatidic acid.
  Journal
Biochem Biophys Res Commun 231:619-22 (1997)
DOI:10.1006/bbrc.1997.6150
  Sequence
[hsa:1902]
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