KEGG   ORTHOLOGY: K04304
Entry
K04304                      KO                                     
Symbol
CXCR7, ACKR3, RDC1
Name
C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
Disease
H02814  Oculomotor-abducens synkinesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
   04061 Viral protein interaction with cytokine and cytokine receptor
    K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
   04050 Cytokine receptors
    K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Chemokine
   CXC Chemokine
    K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
Cytokine receptors [BR:ko04050]
 Chemokine receptors
  CXC Chemokine
   K04304  CXCR7, ACKR3, RDC1; C-X-C chemokine receptor type 7 (atypical chemokine receptor 3)
Other DBs
GO: 0016494
Genes
HSA: 57007(ACKR3)
PTR: 460122(ACKR3)
PPS: 100980618(ACKR3)
GGO: 101126486(ACKR3)
PON: 100458260(ACKR3)
PPYG: 129031946(ACKR3)
NLE: 100588570(ACKR3)
HMH: 116809722(ACKR3)
SSYN: 129488621(ACKR3)
MCC: 694428(ACKR3)
MCF: 102115129(ACKR3)
MTHB: 126932613
MNI: 105473859(ACKR3)
CSAB: 103218146(ACKR3)
CATY: 105578308(ACKR3)
PANU: 101019094(ACKR3)
TGE: 112636678(ACKR3)
MLEU: 105539832(ACKR3)
RRO: 104658029(ACKR3)
RBB: 108540997(ACKR3)
TFN: 117094340(ACKR3)
PTEH: 111553777(ACKR3)
CANG: 105502919(ACKR3) 105526117
CJC: 100405867(ACKR3)
SBQ: 101030558(ACKR3)
CIMI: 108310663(ACKR3)
ANAN: 105704765(ACKR3)
CSYR: 103256789(ACKR3)
MMUR: 105865698(ACKR3)
LCAT: 123643248(ACKR3)
PCOQ: 105814000(ACKR3)
OGA: 100964816(ACKR3)
MMU: 12778(Ackr3)
MCAL: 110297593(Ackr3)
MPAH: 110321751(Ackr3)
RNO: 84348(Ackr3)
MCOC: 116088751(Ackr3)
ANU: 117722494(Ackr3)
ASYL: 127692701(Ackr3)
MUN: 110552566(Ackr3)
CGE: 100774656(Ackr3)
MAUA: 101838690(Ackr3)
PROB: 127226681(Ackr3)
PLEU: 114700693(Ackr3)
MORG: 121447184(Ackr3)
MFOT: 126514304
AAMP: 119821124(Ackr3)
NGI: 103726201(Ackr3)
HGL: 101716371(Ackr3)
CPOC: 100729562(Ackr3)
CCAN: 109700279(Ackr3)
DORD: 105988424(Ackr3)
DSP: 122107217(Ackr3)
DMER: 138819630(Ackr3)
PLOP: 125350156(Ackr3)
NCAR: 124973066 124981364
MMMA: 107133613 107138834(Ackr3)
ITI: 101966519 101970549(Ackr3)
OCU: 100354655
OPI: 101526363(ACKR3)
OCZ: 121151127(ACKR3)
TUP: 102501717(ACKR3)
GVR: 103602135(ACKR3)
CFA: 403964(ACKR3)
CLUD: 112669954(ACKR3)
VVP: 112908760(ACKR3)
VLG: 121497408(ACKR3)
NPO: 129493882(ACKR3)
AML: 100470730(ACKR3)
UMR: 103662644(ACKR3)
UAH: 113250308(ACKR3)
UAR: 123790034(ACKR3)
ELK: 111144188
LLV: 125095396
MPUF: 101680683(ACKR3)
MNP: 132013675(ACKR3)
MLK: 131827297(ACKR3)
NVS: 122902444(ACKR3)
ORO: 101382889(ACKR3)
EJU: 114210820(ACKR3)
ZCA: 113920724(ACKR3)
MLX: 118011896(ACKR3)
NSU: 110570888(ACKR3)
LWW: 102747197(ACKR3)
FCA: 101080817(ACKR3)
PYU: 121014383(ACKR3)
PCOO: 112848449(ACKR3)
PBG: 122481952(ACKR3)
PVIV: 125158926(ACKR3)
LRUF: 124516074
LGF: 123599680(ACKR3)
AJU: 106968409
PTG: 102962531(ACKR3)
PPAD: 109264854(ACKR3)
PUC: 125917064 125917065
PLEZ: 122226831(ACKR3)
HHV: 120229564(ACKR3)
BTA: 509585(ACKR3)
BOM: 102276294(ACKR3)
BIU: 109556563(ACKR3)
BBUB: 102394708(ACKR3)
BBIS: 105004426(ACKR3)
CHX: 102169070(ACKR3)
OAS: 101102850(ACKR3)
BTAX: 128044802(ACKR3)
CSUM: 138072834(ACKR3)
ODA: 120856488(ACKR3)
CCAD: 122437289(ACKR3)
MREE: 136155046(ACKR3)
OVR: 110145283(ACKR3)
MBEZ: 129541336(ACKR3)
SSC: 100515346(ACKR3)
CFR: 102518890(ACKR3)
CBAI: 105063560(ACKR3)
CDK: 105085551(ACKR3)
VPC: 102538428(ACKR3)
BACU: 103016812(ACKR3)
BMUS: 118898247(ACKR3)
LVE: 103072113(ACKR3)
OOR: 101274469(ACKR3)
LALB: 132521991(ACKR3)
GMF: 115857448(ACKR3)
DDP: 132427929(ACKR3)
DLE: 111171969(ACKR3)
PCAD: 102989117(ACKR3)
PSIU: 116757156(ACKR3)
PPHC: 136125933(ACKR3)
NASI: 112404720(ACKR3)
ECB: 100057501(ACKR3)
EPZ: 103565356(ACKR3)
EAI: 106844870(ACKR3)
MYB: 102257104(ACKR3)
MYD: 102775424(ACKR3)
MMYO: 118661545(ACKR3)
MLF: 102418609(ACKR3)
MDT: 132238391(ACKR3)
MYUM: 139015133(ACKR3)
PKL: 118709480(ACKR3)
EFUS: 103283220(ACKR3)
MNA: 107543071(ACKR3)
DRO: 112307876(ACKR3)
SHON: 119003075(ACKR3)
AJM: 119061067(ACKR3)
PDIC: 114494247(ACKR3)
PHAS: 123823207(ACKR3)
MMF: 118625405(ACKR3)
PPAM: 129068270(ACKR3)
HAI: 109373736(ACKR3)
RFQ: 117025459(ACKR3)
PALE: 102894060(ACKR3)
PGIG: 120600758(ACKR3)
PVP: 105305396(ACKR3)
RAY: 107510607(ACKR3)
MJV: 108406710(ACKR3)
TOD: 119256332(ACKR3)
SARA: 101558876(ACKR3)
SFUM: 130030354(ACKR3)
SETR: 126009278(ACKR3)
LAV: 100655766(ACKR3)
TMU: 101343903
ETF: 101661706(ACKR3)
DNM: 101437564(ACKR3)
MDO: 100020044(ACKR3)
GAS: 123247618 123247619(ACKR3)
SHR: 100919342(ACKR3)
AFZ: 127541225 127562975
TVP: 118855736(ACKR3)
PBRV: 138173225(ACKR3)
MLAO: 141489112(ACKR3)
OAA: 100077072(ACKR3)
TACU: 119930972(ACKR3)
GGA: 428997(ACKR3)
PCOC: 116236039(ACKR3)
MGP: 100546352(ACKR3)
CJO: 107316402(ACKR3)
TPAI: 128077149(ACKR3)
LMUT: 125697232(ACKR3)
NMEL: 110399985(ACKR3)
APLA: 101792740(ACKR3)
ACYG: 106034577(ACKR3)
CATA: 118257887(ACKR3)
AFUL: 116490938(ACKR3)
TGU: 100226994(ACKR3)
LSR: 110473506(ACKR3)
SCAN: 103814762(ACKR3)
PMOA: 120499650(ACKR3)
OTC: 121333311(ACKR3)
PRUF: 121351787(ACKR3)
ATRC: 139585518(ACKR3)
GFR: 102032911(ACKR3)
FAB: 101809183(ACKR3)
OMA: 130255680(ACKR3)
PHI: 102108965(ACKR3)
PMAJ: 107207571(ACKR3)
CCAE: 111931854(ACKR3)
CCW: 104694560(ACKR3)
CBRC: 103621853(ACKR3)
ACOE: 138113468(ACKR3)
ETL: 114069508(ACKR3)
ZAB: 102066445(ACKR3)
ZLE: 135450175(ACKR3)
ACHL: 103807007(ACKR3)
SVG: 106861987(ACKR3)
MMEA: 130588895(ACKR3)
HRT: 120755308(ACKR3)
SATI: 136363297(ACKR3)
CCIC: 134052312(ACKR3)
FPG: 101912353(ACKR3)
FCH: 102050446(ACKR3)
CCRI: 104165870(ACKR3)
NNT: 104409752(ACKR3)
SHAB: 115608682(ACKR3)
ACUN: 113482384(ACKR3)
TALA: 104368869(ACKR3)
ACHC: 115343172(ACKR3)
HALD: 104320870(ACKR3)
HLE: 104838257(ACKR3)
AGEN: 126038539
HHAR: 128144377(ACKR3)
GCL: 127018431
CSTI: 104555937(ACKR3)
LDI: 104352833(ACKR3)
MNB: 103776939(ACKR3)
DPUB: 104300532(ACKR3)
PPUS: 135184054(ACKR3)
AVIT: 104278163(ACKR3)
BRHI: 104493417(ACKR3)
EGZ: 104123250(ACKR3)
NNI: 104010215(ACKR3)
PCRI: 104030363(ACKR3)
PCAO: 104050656(ACKR3)
PADL: 103914172(ACKR3)
AFOR: 103903832(ACKR3)
FGA: 104080952(ACKR3)
CBOR: 142083801(ACKR3)
GSTE: 104262718(ACKR3)
CBOY: 140657742(ACKR3)
MAME: 142414358(ACKR3)
CLV: 102092528(ACKR3)
CNIC: 135990330(ACKR3)
MUI: 104539574(ACKR3)
PGUU: 104464951(ACKR3)
PLET: 104617320(ACKR3)
EHS: 104512663(ACKR3)
CMAC: 104485288(ACKR3)
CUCA: 104067376(ACKR3)
TEO: 104373354(ACKR3)
BREG: 104639827(ACKR3)
OHA: 104327816(ACKR3)
ACAR: 104531141(ACKR3)
CPEA: 104388446(ACKR3)
CVF: 104288730(ACKR3)
RTD: 128912626(ACKR3)
CRID: 134518871(ACKR3)
LMIC: 141746609(ACKR3)
AAM: 106484445(ACKR3)
AROW: 112976467(ACKR3)
NPD: 112956050(ACKR3)
TGT: 104569128(ACKR3)
DNE: 112985799(ACKR3)
SCAM: 104151164(ACKR3)
ASN: 102382753(ACKR3)
AMJ: 102574735(ACKR3)
CPOO: 109323067(ACKR3)
GGN: 109301946(ACKR3)
PSS: 102459085(ACKR3)
CIZ: 142017077(ACKR3)
CMY: 102930704(ACKR3)
CCAY: 125644839(ACKR3)
DCC: 119863803(ACKR3)
CPIC: 101952662(ACKR3)
TST: 117885087(ACKR3)
CABI: 116836454(ACKR3)
MRV: 120374261(ACKR3)
ACS: 100561152(ackr3)
ASAO: 132780329(ACKR3)
PVT: 110083709(ACKR3)
SUND: 121936170(ACKR3)
PBI: 103064332(ACKR3)
PMUR: 107298993(ACKR3)
CTIG: 120300383(ACKR3)
TSR: 106547990(ACKR3)
PCAE: 139327073(ACKR3)
APRI: 131199376(ACKR3)
PTEX: 113440994(ACKR3)
NSS: 113419558(ACKR3)
VKO: 123024368(ACKR3)
PMUA: 114582126(ACKR3)
PRAF: 128400532(ACKR3)
ZVI: 118096882(ACKR3)
HCG: 128341099(ACKR3)
GJA: 107114841(ACKR3)
STOW: 125434794(ACKR3)
EMC: 129344821(ACKR3)
XLA: 108703031(ackr3.S) 398310(ackr3.L)
XTR: 594993(ackr3)
NPR: 108788516(ACKR3)
RTEM: 120943889(ACKR3)
ACAT: 141146879(ACKR3)
BBUF: 121008163(ACKR3)
BGAR: 122945317(ACKR3)
DTC: 141091841(ACKR3)
PWL: 138285530(ACKR3)
MUO: 115474069(ACKR3)
GSH: 117361291(ACKR3)
DRE: 100000764(ackr3a) 561050(ackr3b)
SRX: 107709570 107725223 107739947 107748917
SANH: 107670701 107677631 107688828 107695574
SGH: 107555037 107571721 107586318 107596319
CCAR: 109066623 109084855 109084856(ackr3b) 122138484
CAUA: 113050746 113053278 113096829 113098506 113109356
CGIB: 127959707 127964589 128015434 128019794
PTET: 122347246(ackr3b) 122351984(ackr3a)
LROH: 127167222(ackr3b) 127171343(ackr3a)
GRF: 141340764(ackr3a) 141347098(ackr3b)
OMC: 131542349(ackr3b) 131546463(ackr3a)
PPRM: 120460665(ackr3a) 120486089(ackr3b)
RKG: 130069608(ackr3b) 130085931(ackr3a)
MAMB: 125270430(ackr3a) 125274266(ackr3b)
CIDE: 127513908 127518602
CERY: 137010814(ackr3b) 137035657(ackr3a)
MASI: 127445739 127447409 127448101 127449232
TROS: 130555673(ackr3a) 130556732(ackr3b)
TDW: 130425287(ackr3b) 130427569(ackr3a)
MANU: 129450460(ackr3b) 129452081(ackr3a)
PDAB: 135717822(ackr3b) 135733197(ackr3a)
IPU: 108272964(ackr3b)
IFU: 128616150(ackr3b)
PHYP: 113538395(ackr3)
SMEO: 124384552(ackr3b)
TFD: 113634562(ackr3b)
TVC: 132844769(ackr3b)
CGAR: 128526973(ackr3b)
NGRA: 132884933(ackr3b)
TRN: 134316439(ackr3b)
AMEX: 103039898 103047229(ackr3b)
CMAO: 118807738(ackr3b) 118820109(ackr3a)
EEE: 113574065(ackr3) 113588138
CHAR: 105896533(ackr3b) 105908661(ackr3a)
SPIL: 134071504(ackr3b) 134078285(ackr3a)
ASAD: 121694106(ackr3a) 121698338(ackr3b)
TRU: 101071332(ackr3)
TFS: 130529995(ackr3a)
TNG: GSTEN00026044G001
LCO: 104934004 104934108
NCC: 104967653(ackr3)
TBEN: 117469108 117481151
CGOB: 115004963 115026496
PGEO: 117441854 117466989
GACU: 117544310
EMAC: 134860646 134867694(ackr3a)
ELY: 117248261 117249977(ackr3b)
EFO: 125885056(ackr3b) 125899946
PLEP: 121949500 121963042 121963330
SLUC: 116047252 116062396(ackr3b)
ECRA: 117940218 117952915
ESP: 116697944(ackr3)
PFLV: 114551075 114564099
GAT: 120834054
PPUG: 119229110
AFB: 129104616 129111651(ackr3b)
CLUM: 117744441 117751021
PSWI: 130203877(ackr3a)
CANA: 137782809 137794106
CVE: 137868224(ackr3a) 137887175(ackr3b)
MSAM: 119904177(ackr3a) 119909281(ackr3b)
SCHU: 122871948 122885849(ackr3a)
CUD: 121522131
SPUL: 138592273 138603709
LMIX: 132986580(ackr3a)
HTC: 141808906(ackr3a)
ALAT: 119015015(ackr3b) 119026430
ASTR: 137591280 137604862(ackr3a)
MZE: 101467714 101470339
ONL: 100703676 100708828
OAU: 116316531(ackr3b) 116319303(ackr3a)
OLA: 101171710(ackr3)
OML: 112155551(ackr3a)
CSAI: 133444722(ackr3b) 133445881(ackr3a)
XMA: 102218953 102238345
XCO: 114140602 114148407
XHE: 116715697 116723369
PRET: 103459367 103481056
PFOR: 103129464 103134214
PLAI: 106947254 106957809
PMEI: 106919835 106928021
GAF: 122827094 122840070(ackr3a)
PPRL: 129354803 129361503(ackr3a)
CVG: 107101512(ackr3) 107102199
CTUL: 119773793 119797623
GMU: 124861276 124871957
NFU: 107389922(ackr3)
KMR: 108239713(ackr3a)
ALIM: 106532440(ackr3)
NWH: 119419180(ackr3a)
AOCE: 111578933(ackr3a)
EJA: 138200948(ackr3a) 138207148
BFRE: 138629733(ackr3a) 138634355
MCEP: 125018122(ackr3a)
CSEM: 103392071(ackr3)
POV: 109631072(ackr3)
SSEN: 122765404
SSOE: 131455502(ackr3a)
HHIP: 117755103(ackr3a)
HSP: 118120375(ackr3a)
PPLT: 128455579
SMAU: 118282844
LCF: 108881130(ackr3b) 108901609
SDU: 111218781 111235569
SLAL: 111662181 111669704
XGL: 120787452(ackr3b) 120801112(ackr3a)
HCQ: 109531298(ackr3)
SSCV: 125973752(ackr3a)
SBIA: 133512009
PEE: 133411011(ackr3a)
PTAO: 133486939(ackr3a)
BPEC: 110166607(ackr3)
ENY: 140359563(ackr3a)
MALB: 109951374 109971110
BSPL: 114847648(ackr3a)
SJO: 128354569 128368268(ackr3a)
SSCO: 133993319(ackr3a)
TTY: 137192784(ackr3a)
GMH: 115542350(ackr3)
SASA: 106574787(ackr3) 106575680 106582103 106586625
STRU: 115155796 115161130 115179379 115196454
OTW: 112225448 112239413(ackr3b) 112240897
OMY: 110501640 110520437 118941094 118965241
OGO: 124022433(ackr3b) 124042977 124045865
ONE: 115115935 115127964
OKI: 109871439 109886309 109903132 116359815
OKE: 118366473 118372624(ackr3b) 118386214
OMM: 135519137 135543149(ackr3b) 135547440
OCLA: 139380655 139402742 139406122 139412762 139414047
SALP: 111959319 111979005
SNH: 120050514 120051387 120057962 120063738
SFON: 129816843 129821007 129840410 129840433
CCLU: 121536283 121571659 121576054(ackr3b)
ELS: 105023127(ackr3) 105030598
OEP: 134007432(ackr3b)
SFM: 108918924(ackr3)
PKI: 111850195(ackr3)
AANG: 118213911
AROT: 135240660
CCOG: 133116393
LOC: 102688604(ackr3)
PSPA: 121322442 121323517
ARUT: 117403578 117427183
PSEX: 120530697
LCM: 102361431(ACKR3)
CMK: 103186695(ackr3b)
RTP: 109913330
CPLA: 122551338
HOC: 132817210
SCAU: 119960695
LERI: 129698583
HAKA: 140728282(ackr3b)
PMRN: 116938554 116949380 116949384
LRJ: 133345266 133345267 133346086
 » show all
Reference
PMID:22173725
  Authors
Yan X, Cai S, Xiong X, Sun W, Dai X, Chen S, Ye Q, Song Z, Jiang Q, Xu Z
  Title
Chemokine receptor CXCR7 mediates human endothelial progenitor cells survival, angiogenesis, but not proliferation.
  Journal
J Cell Biochem 113:1437-46 (2012)
DOI:10.1002/jcb.24015
Reference
PMID:1675791
  Authors
Sreedharan SP, Robichon A, Peterson KE, Goetzl EJ
  Title
Cloning and expression of the human vasoactive intestinal peptide receptor.
  Journal
Proc Natl Acad Sci U S A 88:4986-90 (1991)
DOI:10.1073/pnas.88.11.4986
  Sequence
[hsa:57007]
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