KEGG ORTHOLOGY: K04716

ORTHOLOGY: K04716

Entry

K04716                      KO

Symbol

SGPP1

Name

sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]

Pathway

map00600

Sphingolipid metabolism

map01100

Metabolic pathways

map04071

Sphingolipid signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K04716  SGPP1; sphingosine-1-phosphate phosphatase 1
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K04716  SGPP1; sphingosine-1-phosphate phosphatase 1
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.-
     K04716  SGPP1; sphingosine-1-phosphate phosphatase 1

Other DBs

RN:	R06520 R06521 R06522

GO:

0042392

Genes

HSA:	81537(SGPP1)

PTR:	467479(SGPP1)

PPS:	100979353(SGPP1)

GGO:	101140990(SGPP1)

PON:	100458471(SGPP1)

NLE:	100591437(SGPP1)

MCC:	709364(SGPP1)

MCF:	102142274(SGPP1)

CSAB:

103229157(SGPP1)

CATY:

105582818(SGPP1)

PANU:

101009539(SGPP1)

TGE:	112629436(SGPP1)

RRO:	104678442(SGPP1)

RBB:	108542435(SGPP1)

TFN:	117069489(SGPP1)

PTEH:

111555760(SGPP1)

CJC:	100414910(SGPP1)

SBQ:	101044802(SGPP1)

CSYR:

103268166(SGPP1)

MMUR:

105878330(SGPP1)

LCAT:

123648208(SGPP1)

OGA:	100943893(SGPP1)

MMU:	81535(Sgpp1)

MCAL:

110307304(Sgpp1)

MPAH:

110324488(Sgpp1)

RNO:	81536(Sgpp1)

MCOC:

116080196(Sgpp1)

MUN:	110557569(Sgpp1)

CGE:	100766871(Sgpp1)

MAUA:

101831227(Sgpp1)

PLEU:

114683641(Sgpp1)

MORG:

121452527(Sgpp1)

AAMP:

119819059(Sgpp1)

NGI:	103747973(Sgpp1)

HGL:	101697333 101698443 101710628(Sgpp1)

CPOC:

100715609(Sgpp1)

CCAN:

109697372(Sgpp1)

DORD:

105983794(Sgpp1)

DSP:	122110036(Sgpp1)

NCAR:

124977848

OCU:	108178643(SGPP1)

OPI:	101527797(SGPP1)

TUP:	102491372(SGPP1)

CFA:	490728(SGPP1)

CLUD:

112657079(SGPP1)

VVP:	112921349(SGPP1)

VLG:	121493754(SGPP1)

AML:	109488741(SGPP1)

UAH:	113246295 113246334

UAR:	123800638(SGPP1)

ELK:

111161192

LLV:

125104831

MPUF:

101673418(SGPP1)

ORO:	101379255(SGPP1)

EJU:	114206788(SGPP1)

ZCA:	113908641(SGPP1)

FCA:	101095345(SGPP1)

PYU:	121031883(SGPP1)

PBG:	122469196(SGPP1)

PTG:	102967184(SGPP1)

PPAD:

109268345(SGPP1)

AJU:	106971302(SGPP1)

HHV:	120238431(SGPP1)

BTA:	516881(SGPP1)

BOM:	102277496(SGPP1)

BIU:	109565238(SGPP1)

BBUB:

102390378(SGPP1)

CHX:	102174749(SGPP1)

OAS:	101108492(SGPP1)

ODA:	120852820(SGPP1)

CCAD:

122443737(SGPP1)

SSC:	100626032(SGPP1)

CFR:	102505600(SGPP1)

CBAI:

105074658(SGPP1)

CDK:	105086202(SGPP1)

VPC:	102535101(SGPP1)

BACU:

103012286(SGPP1)

LVE:	103069005(SGPP1)

OOR:	101274550(SGPP1)

DLE:	111173079(SGPP1)

PCAD:

102973214(SGPP1)

PSIU:

116749890(SGPP1)

ECB:	100061850(SGPP1)

EPZ:	103554332(SGPP1)

EAI:	106839161(SGPP1)

MYB:	102253110(SGPP1)

MYD:	102772311(SGPP1)

MMYO:

118656325(SGPP1)

MLF:	102430160(SGPP1)

MNA:	107545698(SGPP1)

PKL:	118716981(SGPP1)

HAI:	109375914(SGPP1)

DRO:	112311133(SGPP1)

SHON:

118976591(SGPP1)

AJM:	119034866(SGPP1)

PDIC:

114491641(SGPP1)

PHAS:

123808935(SGPP1)

MMF:	118628276(SGPP1)

RFQ:	117023463(SGPP1)

PALE:

102878079(SGPP1)

PGIG:

120603814(SGPP1)

PVP:	105310002(SGPP1)

RAY:	107509326(SGPP1)

MJV:	108395651(SGPP1)

TOD:	119239172(SGPP1)

SARA:

101558610(SGPP1)

LAV:	100676598(SGPP1)

TMU:

101350524

DNM:	101413948(SGPP1)

MDO:	100027518(SGPP1)

GAS:	123237747(SGPP1)

SHR:	100918515(SGPP1)

PCW:	110208454(SGPP1)

OAA:	100080900(SGPP1)

PCOC:

116236795(SGPP1)

MGP:	100543310(SGPP1)

CJO:	107315352(SGPP1)

NMEL:

110401289(SGPP1)

APLA:

101801150(SGPP1)

ACYG:

106037176(SGPP1)

AFUL:

116489655(SGPP1)

TGU:	100221899(SGPP1)

LSR:	110484105(SGPP1)

SCAN:

103826857(SGPP1)

PMOA:

120513518(SGPP1)

OTC:	121332582(SGPP1)

PRUF:

121358243(SGPP1)

GFR:	102040480(SGPP1)

FAB:	101808981(SGPP1)

PHI:	102108318(SGPP1)

PMAJ:

107206227(SGPP1)

CCAE:

111929534(SGPP1)

CCW:	104688935(SGPP1)

CBRC:

103618871(SGPP1)

ETL:	114063206(SGPP1)

ZAB:	102072788(SGPP1)

ACHL:

103798335(SGPP1)

FPG:	101912992(SGPP1)

FCH:	102059905(SGPP1)

CLV:	102098480(SGPP1)

EGZ:	104131675(SGPP1)

NNI:	104010142(SGPP1)

PLET:

104623680(SGPP1)

ACUN:

113480421(SGPP1)

TALA:

104356661(SGPP1)

PADL:

103924257(SGPP1)

ACHC:

115336220(SGPP1)

HALD:

104322139(SGPP1)

CSTI:

104553929(SGPP1)

EHS:	104510193(SGPP1)

CMAC:

104481401(SGPP1)

MUI:	104543308(SGPP1)

FGA:	104082035(SGPP1)

GSTE:

104261922(SGPP1)

LDI:	104340479(SGPP1)

MNB:	103769917(SGPP1)

OHA:	104330068(SGPP1)

AAM:	106483101(SGPP1)

AROW:

112976905(SGPP1)

NPD:	112959665(SGPP1)

DNE:	112991634(SGPP1)

ASN:	102377319(SGPP1)

AMJ:	102576958(SGPP1)

CPOO:

109320652(SGPP1)

GGN:	109299291(SGPP1)

CMY:	102948002(SGPP1)

CPIC:

101941158(SGPP1)

TST:	117876194(SGPP1)

CABI:

116830007(SGPP1)

MRV:	120404350(SGPP1)

ACS:	100554530(sgpp1)

PVT:	110087858(SGPP1)

SUND:

121914804(SGPP1)

PBI:	103050345(SGPP1)

PMUR:

107285160 107293309

TSR:	106543021(SGPP1)

PGUT:

117675170(SGPP1)

VKO:	123026512(SGPP1)

PMUA:

114603505(SGPP1)

ZVI:	118079830(SGPP1)

GJA:	107121444(SGPP1)

STOW:

125427055(SGPP1)

XLA:

101027287

XTR:	549040(sgpp1)

NPR:	108786892(SGPP1)

RTEM:

120920032(SGPP1)

BBUF:

120981946(SGPP1)

BGAR:

122921812(SGPP1)

DRE:	100003745(sgpp1) 556439(si:ch211-212g7.6)

SRX:	107716492 107726595 107736834(sgpp1) 107743975

SANH:

107654933(sgpp1) 107683631 107697306 107701492

SGH:	107553224 107563688 107589063 107602978

CCAR:

109073161 109082491(sgpp1) 109101722

CAUA:

113056817 113063371 113112461 113121036

PPRM:

120463111(sgpp1) 120493748(si:ch211-212g7.6)

MAMB:

125277322(sgpp1b) 125277761 125277764 125277788

IPU:	108257884(sgpp1a) 108263245(sgpp1b)

PHYP:

113541943(sgpp1) 113545242

SMEO:

124376660(sgpp1a) 124398703(sgpp1b)

TFD:	113644517(sgpp1a) 113656550(sgpp1b)

AMEX:

103033561 103043414(sgpp1)

EEE:	113573005 113575535(sgpp1)

TRU:	101069308 101073941(sgpp1)

TNG:	GSTEN00023278G001 GSTEN00030340G001

LCO:	104930364(sgpp1) 104930546

NCC:	104951070 104956487(sgpp1)

CGOB:

115003595 115005059

ELY:	117266618(sgpp1) 117271282

EFO:	125896703 125901195(sgpp1b)

PLEP:

121953821(sgpp1b) 121955641 121963384

SLUC:

116036777(sgpp1) 116065956

ECRA:

117935889(sgpp1) 117961121

ESP:	116670210 116706552

PFLV:

114546634 114573551

GAT:	120808106 120814132 120832846(sgpp1)

PPUG:

119194793 119227401(sgpp1)

MSAM:

119909573 119919153

CUD:	121521592 121526083(sgpp1b)

ALAT:

119004480(sgpp1) 119012176

MZE:	101480011(sgpp1) 101484831

ONL:	100700490(sgpp1) 100711669

OAU:	116310692(sgpp1) 116310703

OLA:	101166766 101173595(sgpp1)

OML:	112140558 112149495(sgpp1) 112158315

XMA:	102217671 102236212

XCO:	114155583 114158888

XHE:	116709640 116734139

PRET:

103457586 103458086

PFOR:

103138616 103147754

PLAI:

106939204 106949072

PMEI:

106906725 106919673(sgpp1)

GAF:	122825836 122846008

CVG:	107082722 107084889

CTUL:

119785105 119792147

GMU:	124855645 124882539

NFU:	107377578 107391642(sgpp1)

KMR:	108242494 108251518(sgpp1)

ALIM:

106516927 106531564(sgpp1)

NWH:	119418191 119427091(sgpp1b)

AOCE:

111566662 111568813(sgpp1)

MCEP:

124999119 125023490(sgpp1b)

CSEM:

103380814 103382704(sgpp1)

POV:	109636161(sgpp1) 109648136

SSEN:

122761556 122783399(sgpp1b)

HHIP:

117756720(sgpp1) 117758166

HSP:	118099589 118116512(sgpp1b)

LCF:	108895644 108901642(sgpp1)

SDU:	111225386 111239742

SLAL:

111652673 111654330

XGL:	120789376 120795346(sgpp1)

HCQ:	109520744 109524863

BPEC:

110153074 110153456

MALB:

109954458 109966615

BSPL:

114849114(sgpp1b) 114850089

SASA:

106571509 106599021(sgpp1)

OTW:	112250420(sgpp1a) 112261702

OMY:	110497831 110529718(si:ch211-212g7.6)

OGO:	123990853 124001379(sgpp1b)

ONE:	115107859 115146155(sgpp1)

SALP:

111954355 111968653(sgpp1)

SNH:	120024085(si:ch211-212g7.6) 120060345(sgpp1)

CCLU:

121539359 121544457 121552384

ELS:	105015553 105017650

SFM:	108919425(sgpp1) 108941948

PKI:	111844461 111851059(sgpp1)

AANG:

118215330(sgpp1) 118230775(si:ch211-212g7.6)

LOC:	102683932(sgpp1)

PSPA:

121324557 121330252

ARUT:

117430327 117974017

LCM:	102367084(SGPP1)

CMK:	103185418(sgpp1b)

RTP:	109914447(sgpp1)

BFO:

118410290

BBEL:

109469942

CIN:	100182290 100182465

SCLV:

120326238 120328410

APLC:

110982172

SKO:	100367222 100367374

AGA:	AgaP_AGAP009675

ACOZ:

AARA:

ASTE:

AAG:

AALB:

CQU:	CpipJ_CPIJ009138

CPII:

BCOO:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209451

BANY:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

HAW:

TNL:

SLIU:

OFU:

PXY:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM323580

FOC:

TPAL:

ZNE:

CSEC:

FCD:

DPX:	DAPPUDRAFT_251767

DMK:

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

EAF:

PPOI:

ISC:	IscW_ISCW021109

RMP:

DPTE:

CSCU:

PTEP:

SDM:

HRO:	HELRODRAFT_122845

LGI:	LOTGIDRAFT_140415 LOTGIDRAFT_54296

PCAN:

112564569 112570185

BGT:	106057009 106057010 106069578 106074606

GAE:	121372716 121380615 121381749

HRF:	124145460 124146650

HRJ:	124267147 124276789

CRG:	105333032 105334190

MYI:	110441852 110446509

PMAX:

MMER:

OBI:

OSN:

LAK:	106165271 106181304

NVE:	5499548 5515990

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

TAD:	TRIADDRAFT_33901

AQU:	100639563 100641496

MBR:	MONBRDRAFT_31293

» show all

Reference

PMID:10859351

Authors

Mandala SM, Thornton R, Galve-Roperh I, Poulton S, Peterson C, Olivera A, Bergstrom J, Kurtz MB, Spiegel S

Title

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death.

Journal

Proc Natl Acad Sci U S A 97:7859-64 (2000)
DOI:10.1073/pnas.120146897

Sequence

[hsa:81537]

LinkDB

ORTHOLOGY: K04717

Entry

K04717                      KO

Symbol

SGPP2

Name

sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]

Pathway

map00600

Sphingolipid metabolism

map01100

Metabolic pathways

map04071

Sphingolipid signaling pathway

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    K04717  SGPP2; sphingosine-1-phosphate phosphotase 2
09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    K04717  SGPP2; sphingosine-1-phosphate phosphotase 2
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.-
     K04717  SGPP2; sphingosine-1-phosphate phosphotase 2

Other DBs

RN:	R06520 R06521 R06522

GO:

0042392

Genes

HSA:	130367(SGPP2)

PTR:	470726(SGPP2)

PPS:	100976002(SGPP2)

GGO:	101154040(SGPP2)

PON:	100462316(SGPP2)

NLE:	100592130(SGPP2)

MCC:	705674(SGPP2)

MCF:	102135818(SGPP2)

CSAB:

103217939(SGPP2)

CATY:

105587000(SGPP2)

PANU:

101016966(SGPP2)

TGE:	112636112(SGPP2)

RRO:	104655908(SGPP2)

RBB:	108532648(SGPP2)

TFN:	117094464(SGPP2)

PTEH:

111549088(SGPP2)

CJC:	100407081(SGPP2)

SBQ:	101051796(SGPP2)

CSYR:

103260071(SGPP2)

MMUR:

105858642(SGPP2)

LCAT:

123643625(SGPP2)

OGA:	100963481(SGPP2)

MMU:	433323(Sgpp2)

MCAL:

110291335(Sgpp2)

MPAH:

110322485(Sgpp2)

RNO:	301543(Sgpp2)

MCOC:

116089242(Sgpp2)

MUN:	110549410(Sgpp2)

CGE:	100760822(Sgpp2)

MAUA:

101828898(Sgpp2)

PLEU:

114706790(Sgpp2)

MORG:

121447305(Sgpp2)

AAMP:

119821637(Sgpp2)

NGI:	103727771(Sgpp2)

HGL:	101701693(Sgpp2)

CPOC:

100731261(Sgpp2)

CCAN:

109698828(Sgpp2)

DORD:

105987962(Sgpp2)

DSP:	122107414(Sgpp2)

NCAR:

124981069

OCU:	100357833(SGPP2)

OPI:	101529574(SGPP2)

TUP:	102497979(SGPP2)

CFA:	610884(SGPP2)

CLUD:

112656620(SGPP2)

VVP:	112922503(SGPP2)

VLG:	121480542(SGPP2)

AML:	105234969(SGPP2)

UMR:	103662865(SGPP2)

UAH:	113250408(SGPP2)

UAR:	123778090(SGPP2)

ELK:

111138525

LLV:

125096034

MPUF:

101681375(SGPP2)

ORO:	101365224(SGPP2)

EJU:	114210860(SGPP2)

ZCA:	113920266(SGPP2)

MLX:	118012006(SGPP2)

FCA:	101083024(SGPP2)

PYU:	121014504(SGPP2)

PBG:	122481830(SGPP2)

PTG:	107180011(SGPP2)

PPAD:

109264996(SGPP2)

AJU:	106975905(SGPP2)

HHV:	120234842(SGPP2)

BTA:	100337041(SGPP2)

BOM:	102286517(SGPP2)

BIU:	109575817(SGPP2)

BBUB:

102409064(SGPP2)

CHX:	102183470(SGPP2)

OAS:	101116130(SGPP2)

ODA:	120854472(SGPP2)

CCAD:

122426310(SGPP2)

SSC:	100524832(SGPP2)

CFR:	102506559(SGPP2)

CBAI:

105064059(SGPP2)

CDK:	105098290(SGPP2)

VPC:	102543563(SGPP2)

BACU:

102998333 102998371(SGPP2)

LVE:	103081882(SGPP2)

OOR:	101276880(SGPP2)

DLE:	111171871(SGPP2)

PCAD:

102990066(SGPP2)

PSIU:

116756572(SGPP2)

ECB:	100060934(SGPP2)

EPZ:	103547286(SGPP2)

EAI:	106832476(SGPP2)

MYB:	102259379(SGPP2)

MYD:	102762633(SGPP2)

MMYO:

118661275(SGPP2)

MLF:	102438562(SGPP2)

MNA:	107526694(SGPP2)

PKL:	118709056(SGPP2)

HAI:	109396189(SGPP2)

DRO:	112307811(SGPP2)

SHON:

118975362(SGPP2)

AJM:	119039064 119050966(SGPP2)

PDIC:

114495375(SGPP2)

PHAS:

123828190(SGPP2)

MMF:	118625850(SGPP2)

RFQ:	117025771(SGPP2)

PALE:

102894969(SGPP2)

PGIG:

120587707(SGPP2)

PVP:	105291100(SGPP2)

RAY:	107516746(SGPP2)

MJV:	108398001(SGPP2)

TOD:	119256253(SGPP2)

SARA:

101557193(SGPP2)

LAV:	100669348(SGPP2)

TMU:

101356122

DNM:	101419582(SGPP2)

MDO:	100022862(SGPP2)

GAS:	123240169(SGPP2)

SHR:	100920724(SGPP2)

PCW:	110219500(SGPP2)

OAA:	100074162(SGPP2)

GGA:	424813(SGPP2)

PCOC:

116230932(SGPP2)

MGP:	100550401(SGPP2)

CJO:	107318029(SGPP2)

NMEL:

110397785(SGPP2)

APLA:

101797259(SGPP2)

ACYG:

106036188(SGPP2)

AFUL:

116492578(SGPP2)

TGU:	100226252(SGPP2)

LSR:	110483631(SGPP2)

SCAN:

103815661(SGPP2)

PMOA:

120508563(SGPP2)

OTC:	121341164(SGPP2)

PRUF:

121357974(SGPP2)

GFR:	102043416(SGPP2)

FAB:	101809677(SGPP2)

PHI:	102101175(SGPP2)

PMAJ:

107209013(SGPP2)

CCAE:

111933562(SGPP2)

CCW:	104693093(SGPP2)

CBRC:

103612041(SGPP2)

ETL:	114067632(SGPP2)

ZAB:	102068032(SGPP2)

ACHL:

103801979(SGPP2)

FPG:	101914913(SGPP2)

FCH:	102053072(SGPP2)

CLV:	102092199(SGPP2)

EGZ:	104135441(SGPP2)

NNI:	104012997(SGPP2)

PLET:

104613621(SGPP2)

PCRI:

104023768(SGPP2)

ACUN:

113483359(SGPP2)

TALA:

104365207(SGPP2)

PADL:

103917899

ACHC:

115347624(SGPP2)

HALD:

104320842(SGPP2)

CSTI:

104560326(SGPP2)

EHS:	104506484(SGPP2)

FGA:	104078608(SGPP2)

GSTE:

104259034(SGPP2)

LDI:	104349562(SGPP2)

MNB:	103769926(SGPP2)

OHA:	104337999(SGPP2)

AAM:

106485849

AROW:

112969612(SGPP2)

NPD:	112947966(SGPP2)

DNE:	112988929(SGPP2)

ASN:	102382033(SGPP2)

AMJ:	102557931(SGPP2)

CPOO:

109308643(SGPP2)

GGN:	109288203(SGPP2)

PSS:	102450918(SGPP2)

CMY:	102946621(SGPP2)

CPIC:

101946541(SGPP2)

TST:	117883321(SGPP2)

CABI:

116838437(SGPP2)

MRV:	120372303(SGPP2)

ACS:	100566481(sgpp2)

PVT:	110079978(SGPP2)

SUND:

121925195(SGPP2)

PBI:	103057174(SGPP2)

PMUR:

107289157(SGPP2)

TSR:	106540099(SGPP2)

PGUT:

117678383(SGPP2)

VKO:	123024842(SGPP2)

PMUA:

114597792(SGPP2)

ZVI:	118093453(SGPP2)

GJA:	107115866(SGPP2)

STOW:

125438314(SGPP2)

XLA:	100036888(sgpp2.L) 108717467(sgpp2.S)

XTR:	100489794(sgpp2)

NPR:	108796930(SGPP2)

RTEM:

120936578(SGPP2)

BBUF:

120997730(SGPP2)

BGAR:

122935941(SGPP2)

DRE:	100330698(sgpp2)

SRX:	107705636 107722257

SANH:

107669878 107670120(sgpp2)

SGH:	107558808 107585790

CCAR:

109104165 109104170

CAUA:

113058699

PPRM:

120483580(sgpp2)

MAMB:

125248633(sgpp2)

IPU:	108277594 108277997

PHYP:

113544525

SMEO:

124394586(sgpp2)

TFD:	113637873(sgpp2)

AMEX:

103045304(sgpp2)

EEE:	113578720(sgpp2)

TRU:	101075825(sgpp2)

TNG:	GSTEN00026737G001 GSTEN00026738G001

LCO:	104934363(sgpp2)

NCC:

104948104

CGOB:

115017976(sgpp2)

ELY:	117259546(sgpp2)

EFO:	125888257(sgpp2)

PLEP:

121943690(sgpp2)

SLUC:

116038901(sgpp2)

ECRA:

117939798(sgpp2)

ESP:	116673003(sgpp2)

PFLV:

114553071(sgpp2)

PPUG:

119214998(sgpp2)

MSAM:

119882788(sgpp2)

CUD:	121523985(sgpp2)

ALAT:

119008881(sgpp2)

MZE:	101471415(sgpp2)

ONL:	100698709(sgpp2)

OAU:	116328148(sgpp2)

OLA:	101156907(sgpp2)

OML:	112149309(sgpp2)

XMA:	102225026(sgpp2)

XCO:	114161625(sgpp2)

XHE:	116737385(sgpp2)

PRET:

103474930(sgpp2)

PFOR:

103145235(sgpp2)

PLAI:

106953862(sgpp2)

PMEI:

106920630(sgpp2)

GAF:	122832568(sgpp2)

CVG:

107081276

CTUL:

119774559(sgpp2)

GMU:	124884485(sgpp2)

NFU:	107380792(sgpp2)

KMR:	108228397(sgpp2)

ALIM:

106523275(sgpp2)

NWH:	119429236 119429238

AOCE:

111577125(sgpp2)

MCEP:

125013098(sgpp2)

CSEM:

103377830(sgpp2)

POV:	109634441(sgpp2)

SSEN:

122773506(sgpp2)

HHIP:

117773456(sgpp2)

HSP:	118105667(sgpp2)

LCF:	108888205(sgpp2)

SDU:	111232860(sgpp2)

SLAL:

111671281(sgpp2)

XGL:	120792150(sgpp2)

HCQ:	109510750(sgpp2)

BPEC:

110154580(sgpp2)

MALB:

109951303(sgpp2)

BSPL:

114867693(sgpp2)

SASA:

106581310(sgpp2) 106613137

OTW:	112267254(sgpp2)

OMY:	110504111(sgpp2)

OGO:	124006527(sgpp2)

ONE:	115141962(sgpp2)

SALP:

111957842(sgpp2)

SNH:	120028482(sgpp2)

CCLU:

121567705

ELS:	105017512(sgpp2)

SFM:	108932149(sgpp2)

PKI:	111860299(sgpp2)

AANG:

118208881(sgpp2)

LOC:	102693517(sgpp2)

PSPA:

121323448 121326801(sgpp2)

ARUT:

117416540(sgpp2)

LCM:	102359263(SGPP2)

CMK:	103176344(sgpp2)

RTP:	109914278 109919317

SPU:

APLC:

CNS:

LDC:

DCI:

HAZT:

DSV:

RSAN:

RMP:

DFR:

MMER:

SRE:	PTSG_03097

DDI:	DDB_G0272260(sppA)

DPP:	DICPUDRAFT_149430

ACAN:

ACA1_369180

BCR:	BCAH187_A2364

BAL:	BACI_c22090

BNC:

BCF:

BMOB:

Reference

PMID:12411432

Authors

Ogawa C, Kihara A, Gokoh M, Igarashi Y

Title

Identification and characterization of a novel human sphingosine-1-phosphate phosphohydrolase, hSPP2.

Journal

J Biol Chem 278:1268-72 (2003)
DOI:10.1074/jbc.M209514200

Sequence

[hsa:130367]

LinkDB

REACTION: R06522

Entry

R06522                      Reaction

Name

3-sn-phosphatidate phosphohydrolase

Definition

Ceramide 1-phosphate + H2O <=> N-Acylsphingosine + Orthophosphate

Equation

C02960 + C00001 <=> C00195 + C00009

Comment

phosphohydrolase

Reaction class

RC00017

C00195_C02960

Enzyme

3.1.3.4 3.1.3.-

Pathway

rn00600

Sphingolipid metabolism

rn01100

Metabolic pathways

Orthology

K01080

phosphatidate phosphatase [EC:3.1.3.4]

K04716

sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-]

K04717

sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-]

LinkDB

DBGET integrated database retrieval system