KEGG ORTHOLOGY: K04723

ORTHOLOGY: K04723

Entry

K04723                      KO

Symbol

IL1RAP

Name

interleukin 1 receptor accessory protein

Pathway

map04010

MAPK signaling pathway

map04060

Cytokine-cytokine receptor interaction

map04659

Th17 cell differentiation

map04750

Inflammatory mediator regulation of TRP channels

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04723  IL1RAP; interleukin 1 receptor accessory protein
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04723  IL1RAP; interleukin 1 receptor accessory protein
09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    K04723  IL1RAP; interleukin 1 receptor accessory protein
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K04723  IL1RAP; interleukin 1 receptor accessory protein
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K04723  IL1RAP; interleukin 1 receptor accessory protein
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IL1 receptor family
   K04723  IL1RAP; interleukin 1 receptor accessory protein

Genes

HSA:	3556(IL1RAP)

PTR:	460935(IL1RAP)

PPS:	100990776(IL1RAP)

GGO:	101126854(IL1RAP)

PON:	100172432(IL1RAP)

PPYG:

129033697(IL1RAP)

NLE:	100580986(IL1RAP)

HMH:	116479965(IL1RAP)

SSYN:

134732995(IL1RAP)

MCC:	574387(IL1RAP)

MCF:	102133222(IL1RAP)

MTHB:

126948023

MNI:	105470858(IL1RAP)

CSAB:

103241903(IL1RAP)

CATY:

105575191(IL1RAP)

PANU:

100998471(IL1RAP)

TGE:	112619670(IL1RAP)

MLEU:

105540660(IL1RAP)

RRO:	104680048(IL1RAP)

RBB:	108530480(IL1RAP)

TFN:	117084381(IL1RAP)

PTEH:

111544285(IL1RAP)

CANG:

105525839(IL1RAP)

CJC:	100392625(IL1RAP)

SBQ:	101040233(IL1RAP)

CIMI:

108302897

ANAN:

105714847(IL1RAP)

CSYR:

103270923(IL1RAP)

MMUR:

105860441(IL1RAP)

LCAT:

123630388

PCOQ:

105808785(IL1RAP)

OGA:	100952305(IL1RAP)

MMU:	16180(Il1rap)

MCAL:

110311552(Il1rap)

MPAH:

110329561(Il1rap)

RNO:	25466(Il1rap)

MCOC:

116085769(Il1rap)

ANU:	117718055(Il1rap)

ASYL:

127666044(Il1rap)

MUN:	110541070(Il1rap)

CGE:	100771447(Il1rap)

MAUA:

101842609

PROB:

127227021(Il1rap)

PLEU:

114697095

PMAV:

102924974(Il1rap)

MORG:

121464952

MFOT:

126512301

AAMP:

119825053

NGI:	103739339(Il1rap)

HGL:	101707386(Il1rap)

CPOC:

100714704(Il1rap)

CCAN:

109683830 109683835

DORD:

105988011(Il1rap)

DSP:

122098975

DMER:

138832226(Il1rap)

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

OCZ:

TUP:	102486497(IL1RAP)

GVR:	103599674(IL1RAP)

CFA:	488126(IL1RAP)

CLUD:

112645830

VVP:	112926311(IL1RAP)

VLG:	121477359 121496032

NPO:	129498565(IL1RAP)

AML:	100472192(IL1RAP)

UMR:

103676019

UAH:	113253525(IL1RAP)

UAR:

123801281

ELK:

111151093

LLV:

125102154

MPUF:

101683223(IL1RAP)

MNP:	132011933(IL1RAP)

MLK:	131824725(IL1RAP)

NVS:

122908806

ORO:	101372824(IL1RAP)

EJU:	114207120(IL1RAP)

ZCA:

113917532

MLX:	118006943(IL1RAP)

NSU:

110582733

LWW:

102741894

FCA:	101094125(IL1RAP)

PYU:

121034154

PCOO:

112849639(IL1RAP)

PBG:

122491608

PVIV:

125175636(IL1RAP)

LRUF:

124526888

LGF:

123611088

AJU:

106968030

PTG:	102949407(IL1RAP)

PPAD:

109275315(IL1RAP)

PUC:

125921084

PLEZ:

122230069

HHV:

120233109

BTA:	539334(IL1RAP)

BOM:	102285629(IL1RAP)

BIU:	109556715(IL1RAP)

BBUB:

102396581

BBIS:

104996445(IL1RAP)

CHX:	102188711(IL1RAP)

OAS:	101108354(IL1RAP)

BTAX:

128054017(IL1RAP)

CSUM:

138078686(IL1RAP)

ODA:

120872697

CCAD:

122444794

MREE:

136173035(IL1RAP)

OVR:	110135437(IL1RAP)

MBEZ:

129544437(IL1RAP)

SSC:	100628318(IL1RAP)

CFR:	102517398(IL1RAP)

CBAI:

105072355(IL1RAP)

CDK:	105097548(IL1RAP)

VPC:	102545266(IL1RAP)

BACU:

103002906(IL1RAP)

BMUS:

118894663

LVE:	103085088(IL1RAP)

OOR:	101285541(IL1RAP)

LALB:

132521081(IL1RAP)

GMF:	115855462(IL1RAP)

DDP:	132424827(IL1RAP)

DLE:	111172703(IL1RAP)

PCAD:

102994287(IL1RAP)

PSIU:

116753487(IL1RAP)

PPHC:

136122153(IL1RAP)

NASI:

112396524(IL1RAP)

ECB:	100068726(IL1RAP)

EPZ:	103564852(IL1RAP)

EAI:

106832560

MYB:	102239162 102247506(IL1RAP)

MYD:	102771155(IL1RAP)

MMYO:

118677195

MLF:	102421835(IL1RAP)

MDT:	132230235(IL1RAP)

MYUM:

139003992(IL1RAP)

PKL:

118722686

EFUS:

103295167(IL1RAP)

MNA:	107527297(IL1RAP)

DRO:	112301004(IL1RAP)

SHON:

118982222

AJM:	119039100(IL1RAP)

PDIC:

114490986

PHAS:

123827290

MMF:

118617067

PPAM:

129079880(IL1RAP)

HAI:	109371236(IL1RAP)

RFQ:	117036159(IL1RAP)

PALE:

102892819(IL1RAP)

PGIG:

120593046

PVP:	105306481(IL1RAP)

RAY:

107505912

MJV:

108384285

TOD:	119257393(IL1RAP)

SARA:

101558845(IL1RAP)

SFUM:

130030425(IL1RAP)

SETR:

126012158

LAV:	100666654(IL1RAP)

TMU:

101349040

ETF:

101662924

DNM:	101442775(IL1RAP)

MDO:	100016835(IL1RAP)

GAS:

123242010

SHR:	100933140(IL1RAP)

AFZ:

127558323

PCW:	110193129(IL1RAP)

TVP:

118848548

PBRV:

138157649(IL1RAP)

OAA:

100081686

TACU:

119930633

GGA:	424908(IL1RAP)

PCOC:

116235339(IL1RAP)

MGP:	100549067(IL1RAP)

CJO:	107318248(IL1RAP)

TPAI:

128082822(IL1RAP)

LMUT:

125697777

NMEL:

110398225

APLA:

101795740

ACYG:

106047606(IL1RAP)

CATA:

118246954(IL1RAP)

AFUL:

116492383(IL1RAP)

TGU:	100232686(IL1RAP)

LSR:	110473903(IL1RAP)

SCAN:

103815624(IL1RAP)

PMOA:

120504323

OTC:

121336666

PRUF:

121353838

ATRC:

139594987(IL1RAP)

GFR:	102034831(IL1RAP)

FAB:	101816129(IL1RAP)

OMA:	130256971(IL1RAP)

PHI:	102099952(IL1RAP)

PMAJ:

107208944(IL1RAP)

CCAE:

111933457(IL1RAP)

CCW:

104687925

CBRC:

103625212(IL1RAP)

ACOE:

138114649(IL1RAP)

ETL:	114057591(IL1RAP)

ZAB:	102075069(IL1RAP)

ZLE:	135451689(IL1RAP)

ACHL:

103809529(IL1RAP)

SVG:	106862525(IL1RAP)

MMEA:

130584332(IL1RAP)

HRT:	120757315(IL1RAP)

SATI:

136365478(IL1RAP)

CCIC:

134047829(IL1RAP)

FPG:	101913890(IL1RAP)

FCH:	102059926(IL1RAP)

CCRI:

104159200 104159495

NNT:	104403920(IL1RAP)

SHAB:

115611827(IL1RAP)

ACUN:

113483509(IL1RAP)

TALA:

104361937

ACHC:

115347332

HALD:

104324400(IL1RAP)

HLE:	104835187(IL1RAP)

AGEN:

126039589

HHAR:

128149035(IL1RAP)

GCL:

127020238

CSTI:

104557026(IL1RAP)

LDI:	104348206(IL1RAP)

MNB:	103773940(IL1RAP)

DPUB:

104300719(IL1RAP)

PPUS:

135186749(IL1RAP)

AVIT:

104274619(IL1RAP)

BRHI:

104494043(IL1RAP)

EGZ:

104123380

NNI:	104015670(IL1RAP)

PCRI:

104028254(IL1RAP)

PCAO:

104045135(IL1RAP)

PADL:

103925383(IL1RAP)

AFOR:

103901458(IL1RAP)

FGA:	104081140(IL1RAP)

CBOR:

142085336(IL1RAP)

GSTE:

104257084

CBOY:

140654151(IL1RAP)

MAME:

142412259(IL1RAP)

CLV:	102092020(IL1RAP)

CNIC:

135991618(IL1RAP)

MUI:	104534433(IL1RAP)

PGUU:

104468762(IL1RAP)

PLET:

104618397(IL1RAP)

EHS:	104505863(IL1RAP)

CMAC:

104480365(IL1RAP)

CUCA:

104063466(IL1RAP)

TEO:	104378275(IL1RAP)

BREG:

104642383(IL1RAP)

OHA:	104326853(IL1RAP)

ACAR:

104532213(IL1RAP)

CPEA:

104390724(IL1RAP)

CVF:	104285029(IL1RAP)

RTD:	128911588(IL1RAP)

CRID:

134517247(IL1RAP)

LMIC:

141744949(IL1RAP)

AAM:	106498193(IL1RAP)

AROW:

112968552(IL1RAP)

NPD:	112952527(IL1RAP)

TGT:	104565752(IL1RAP)

DNE:	112979369(IL1RAP)

SCAM:

104148795(IL1RAP)

ASN:	102387107(IL1RAP)

AMJ:	102567774(IL1RAP)

CPOO:

109308553(IL1RAP)

GGN:	109288108(IL1RAP)

PSS:	102445541(IL1RAP)

CIZ:	142018421(IL1RAP)

CMY:

CCAY:

DCC:

CPIC:

TST:	117882923(IL1RAP)

CABI:

116823029(IL1RAP)

MRV:

120372292

ACS:	100563166(il1rap)

ASAO:

132770367(IL1RAP)

PVT:	110085948(IL1RAP)

SUND:

121925723

PBI:	103056190 103067821

PMUR:

107299035(IL1RAP)

CTIG:

120319821

TSR:

106538453

PGUT:

117669824(IL1RAP)

APRI:

131201204(IL1RAP)

PTEX:

113451499(IL1RAP)

NSS:	113426163(IL1RAP)

VKO:

123036789

PMUA:

114598124(IL1RAP)

PRAF:

128414909(IL1RAP)

ZVI:	118093688(IL1RAP)

HCG:	128350146(IL1RAP)

GJA:	107113540(IL1RAP)

STOW:

125438223

EMC:	129332502(IL1RAP)

XLA:	108716971(il1rap.L) 108718047(il1rap.S)

XTR:	100216065(il1rap)

NPR:	108804591(IL1RAP)

RTEM:

120936855

ACAT:

141139861(IL1RAP)

PADS:

140328546(IL1RAP)

BBUF:

120997979

BGAR:

122934099

DTC:	141100745(IL1RAP)

PWL:	138265221(IL1RAP)

MUO:	115478481(IL1RAP)

GSH:	117366942(IL1RAP)

DRE:	100331351(il1rap)

SRX:	107725747 107756204

SANH:

107670125 107689596

SGH:	107551856 107600813

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:	141285241 141285445

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

137004141(il1rap)

MASI:

127422594 127429928

TROS:

130564586

TDW:

130429068

MANU:

129438685(il1rap)

PDAB:

135770687(il1rap)

IPU:

IFU:

PHYP:

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113588549(il1rap)

CHAR:

105909293

SPIL:

134099631

ASAD:

121683671

TRU:	105418371(il1rap)

TFS:

130534441

TNG:	GSTEN00021168G001

LCO:	104939698(il1rap)

TBEN:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

PFLV:

114553249(il1rap)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

137790547(il1rap)

CVE:	137867964(il1rap)

MSAM:

119882583

SCHU:

122878575

CUD:

121522567

SPUL:

138597223(il1rap)

LMIX:

132980923

HTC:	141797636(il1rap)

ALAT:

119010026

ASTR:

137597080(il1rap)

MZE:	101469783 101476087

ONL:	100703991(il1rap) 102075875

OAU:	116329762 120432798

OLA:	101168842(il1rap)

OML:

112149688

CSAI:

133442127

XMA:	102222389(il1rap)

XCO:	114161721(il1rap)

XHE:	116737685(il1rap)

PRET:

103460066

PFOR:

103150889(il1rap)

PLAI:

106962667(il1rap)

PMEI:

106933700(il1rap)

GAF:

122832755

PPRL:

129359369

CVG:	107086872(il1rap)

CTUL:

GMU:

NFU:

KMR:

ALIM:

106511885(il1rap) 106536182

NWH:

119410987

EJA:	138212660(il1rap)

BFRE:

138635258(il1rap)

MCEP:

125013951

CSEM:

103378400(il1rap)

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:	111216885(il1rap)

SLAL:

111663357(il1rap)

XGL:

HCQ:

SSCV:

PEE:

PTAO:

BPEC:

110162875(il1rap)

ENY:

140372023

MALB:

109973263(il1rap)

BSPL:

114868316

SJO:

128360927

GMH:	115528838(il1rap)

SASA:

100136401(il-1racp)

STRU:

OTW:

OMY:

OGO:

ONE:

OKI:

OKE:

OMM:

OCLA:

SALP:

SNH:

SFON:

CCLU:

121560263 121567275 123490248

ELS:

105006651

OEP:

134029005

SFM:	108922149(il1rap)

PKI:	111843097(il1rap)

AANG:

118210208

AROT:

135235674

CCOG:

133108006

LOC:	102695221(il1rap)

PSPA:

121323555 121326943

ARUT:

117416597 117423775

PSEX:

120537032

LCM:	102354139(IL1RAP)

CMK:

103187976

RTP:	109913741 125484712

CPLA:

CPUN:

HOC:

SCAU:

LERI:

HAKA:

CSEC:

Reference

PMID:9371760

Authors

Huang J, Gao X, Li S, Cao Z

Title

Recruitment of IRAK to the interleukin 1 receptor complex requires interleukin 1 receptor accessory protein.

Journal

Proc Natl Acad Sci U S A 94:12829-32 (1997)
DOI:10.1073/pnas.94.24.12829

Sequence

[hsa:3556]

LinkDB

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