KEGG   ORTHOLOGY: K05554
Entry
K05554                      KO                                     
Symbol
actVII
Name
aromatase [EC:4.2.1.-]
Pathway
map01056  Biosynthesis of type II polyketide backbone
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Reaction
R09265  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    K05554  actVII; aromatase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K05554  actVII; aromatase
   01008 Polyketide biosynthesis proteins
    K05554  actVII; aromatase
Lipid biosynthesis proteins [BR:ko01004]
 Polyketide synthase
  Component type
   K05554  actVII; aromatase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     K05554  actVII; aromatase
Genes
MINT: C7M51_04359
PLU: plu4187
PLUM: A4R40_20765
DLA: I6G47_07190
HOE: IMCC20628_03255
ABF: AMK58_25500
BPIT: BPIT_33920
APIB: G8C43_05915
MANA: MAMMFC1_01621
MSAO: MYCSP_12685
SCO: SCO5090(SCBAC28G1.16)
SFI: SFUL_4006
SHY: SHJG_1197
SFA: Sfla_5325
SBH: SBI_06853
SVE: SVEN_5984
SALS: SLNWT_5125
STRP: F750_1298
STRE: GZL_p00218
SLD: T261_6834
SLE: sle_03410(sle_03410)
SALU: DC74_6594
SALL: SAZ_34290
STRD: NI25_18975
SLAU: SLA_3088
SALJ: SMD11_0678(actVII) SMD11_1146(actVII) SMD11_6048(actVII)
LMOI: VV02_05835
TFU: Tfu_1222
TCU: Tcur_2780
AORI: SD37_09345
SESP: BN6_54900
KAL: KALB_7824
MIL: ML5_4410
 » show all
Reference
PMID:1527048
  Authors
Fernandez-Moreno MA, Martinez E, Boto L, Hopwood DA, Malpartida F
  Title
Nucleotide sequence and deduced functions of a set of cotranscribed genes of Streptomyces coelicolor A3(2) including the polyketide synthase for the antibiotic actinorhodin.
  Journal
J Biol Chem 267:19278-90 (1992)
  Sequence
[sco:SCO5090]
Reference
PMID:7868592
  Authors
Kim ES, Cramer KD, Shreve AL, Sherman DH
  Title
Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species.
  Journal
J Bacteriol 177:1202-7 (1995)
DOI:10.1128/JB.177.5.1202-1207.1995
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