KEGG   ORTHOLOGY: K05862
Entry
K05862                      KO                                     
Symbol
VDAC1
Name
voltage-dependent anion channel protein 1
Pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04217  Necroptosis
map04218  Cellular senescence
map04613  Neutrophil extracellular trap formation
map04621  NOD-like receptor signaling pathway
map04979  Cholesterol metabolism
map05010  Alzheimer disease
map05012  Parkinson disease
map05014  Amyotrophic lateral sclerosis
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05131  Shigellosis
map05164  Influenza A
map05166  Human T-cell leukemia virus 1 infection
map05208  Chemical carcinogenesis - reactive oxygen species
map05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05862  VDAC1; voltage-dependent anion channel protein 1
   04022 cGMP-PKG signaling pathway
    K05862  VDAC1; voltage-dependent anion channel protein 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05862  VDAC1; voltage-dependent anion channel protein 1
   04218 Cellular senescence
    K05862  VDAC1; voltage-dependent anion channel protein 1
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K05862  VDAC1; voltage-dependent anion channel protein 1
   04621 NOD-like receptor signaling pathway
    K05862  VDAC1; voltage-dependent anion channel protein 1
  09154 Digestive system
   04979 Cholesterol metabolism
    K05862  VDAC1; voltage-dependent anion channel protein 1
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K05862  VDAC1; voltage-dependent anion channel protein 1
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05164 Influenza A
    K05862  VDAC1; voltage-dependent anion channel protein 1
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K05862  VDAC1; voltage-dependent anion channel protein 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05012 Parkinson disease
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05014 Amyotrophic lateral sclerosis
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05016 Huntington disease
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05017 Spinocerebellar ataxia
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05020 Prion disease
    K05862  VDAC1; voltage-dependent anion channel protein 1
   05022 Pathways of neurodegeneration - multiple diseases
    K05862  VDAC1; voltage-dependent anion channel protein 1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K05862  VDAC1; voltage-dependent anion channel protein 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K05862  VDAC1; voltage-dependent anion channel protein 1
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K05862  VDAC1; voltage-dependent anion channel protein 1
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial protein import machinery
  Outer membrane
   Porin
    K05862  VDAC1; voltage-dependent anion channel protein 1
Ion channels [BR:ko04040]
 Chloride channels
  Maxi chloride channel (VDAC)
   K05862  VDAC1; voltage-dependent anion channel protein 1
Other DBs
GO: 0008308
TC: 1.B.8.1
Genes
HSA: 7416(VDAC1)
PTR: 742793 745717(VDAC1)
PPS: 100982601 100983168(VDAC1)
GGO: 101127243(VDAC1) 109024694 115935285
PON: 100435393 100460133(VDAC1)
PPYG: 129036887(VDAC1)
NLE: 100595164(VDAC1)
HMH: 116471501(VDAC1) 116811837
SSYN: 129457841(VDAC1) 129476183
MCC: 710045(VDAC1)
MCF: 101864983(VDAC1)
MTHB: 126956005
MNI: 105467147(VDAC1)
CSAB: 103244541(VDAC1)
CATY: 105599763(VDAC1)
PANU: 101020566(VDAC1)
TGE: 112625752(VDAC1)
MLEU: 105531327(VDAC1)
RRO: 104659812(VDAC1) 115894591 115895711
RBB: 108529563(VDAC1)
TFN: 117065867(VDAC1) 117098307
PTEH: 111529272(VDAC1)
CANG: 105518210(VDAC1)
CJC: 100399873(VDAC1)
SBQ: 101031406(VDAC1) 104649961
CIMI: 108307148(VDAC1)
ANAN: 105709659(VDAC1) 105715904
CSYR: 103268316(VDAC1)
MMUR: 105869973(VDAC1)
LCAT: 123637772(VDAC1)
PCOQ: 105816029(VDAC1)
OGA: 100948868(VDAC1)
MMU: 22333(Vdac1)
MCAL: 110294695 110304481(Vdac1)
MPAH: 110331342(Vdac1)
RNO: 83529(Vdac1)
MCOC: 116078655(Vdac1) 116099029
ANU: 117711430(Vdac1) 117717634
ASYL: 127694546(Vdac1)
MUN: 110549632(Vdac1)
CGE: 100750613 100765792(Vdac1)
MAUA: 106023283(Vdac1)
PROB: 127219298(Vdac1)
PLEU: 114681917(Vdac1) 114691928
MORG: 121456504(Vdac1)
MFOT: 126510981
AAMP: 119812709(Vdac1)
NGI: 103729749(Vdac1)
HGL: 101708247(Vdac1)
CPOC: 100723897(Vdac1)
CCAN: 109697584(Vdac1)
DORD: 105996772(Vdac1)
DSP: 122115367(Vdac1)
PLOP: 125341918(Vdac1) 125358491
NCAR: 124986880
MMMA: 107146908 107148006(Vdac1)
ITI: 101968366(Vdac1)
OCU: 100008751(VDAC1) 100349506
OPI: 101526482(VDAC1)
TUP: 102485453(VDAC1)
GVR: 103592400(VDAC1)
CFA: 102152873 474681(VDAC1)
CLUD: 112671433 118350204(VDAC1)
VVP: 112917061(VDAC1)
VLG: 121495756(VDAC1)
NPO: 129495115(VDAC1)
AML: 100463625(VDAC1)
UMR: 103663818(VDAC1)
UAH: 113261734(VDAC1)
UAR: 123790351(VDAC1)
ELK: 111141207
LLV: 125081242 125100315
MPUF: 101679422(VDAC1)
MNP: 131998822 132028515(VDAC1)
MLK: 131832037(VDAC1) 131836545
NVS: 122891745(VDAC1) 122900317 122904870
ORO: 101375766(VDAC1)
EJU: 114209486(VDAC1)
ZCA: 113927034 113928933(VDAC1) 113933268
MLX: 118004524 118016634(VDAC1)
NSU: 110591289(VDAC1) 110594300
LWW: 102734457(VDAC1) 102751218
FCA: 101098515(VDAC1) 102899304
PYU: 121010701(VDAC1)
PCOO: 112861387(VDAC1)
PBG: 122487389(VDAC1)
PVIV: 125170847(VDAC1)
LRUF: 124505439 124515603
LGF: 123603753(VDAC1)
AJU: 106984918
PTG: 102959401(VDAC1)
PPAD: 109250866(VDAC1)
PUC: 125933210 125935487
PLEZ: 122200191 122217699(VDAC1)
HHV: 120238512(VDAC1)
BTA: 282119(VDAC1)
BOM: 102266916(VDAC1) 102276673
BIU: 109562011(VDAC1)
BBUB: 102409656(VDAC1)
BBIS: 104991863(VDAC1)
CHX: 102173290(VDAC1)
OAS: 100145866(VDAC1)
BTAX: 128050636(VDAC1) 128058634
CSUM: 138086414(VDAC1)
ODA: 120863663(VDAC1)
CCAD: 122439923(VDAC1)
MREE: 136156112(VDAC1)
OVR: 110146935(VDAC1)
MBEZ: 129558217(VDAC1)
SSC: 397010(VDAC1)
CFR: 102518825(VDAC1) 116669325
CBAI: 105082119(VDAC1)
CDK: 105090242(VDAC1)
VPC: 102538007(VDAC1)
BACU: 103017981(VDAC1)
BMUS: 118882326 118890922 118892431(VDAC1)
LVE: 103073695(VDAC1)
OOR: 101289999(VDAC1)
LALB: 132517061(VDAC1) 132524404
DLE: 111182441(VDAC1)
PCAD: 102974857 102991951(VDAC1) 102992414
PSIU: 116741397 116751471(VDAC1)
PPHC: 136120933(VDAC1)
NASI: 112399681(VDAC1)
ECB: 100062974(VDAC1)
EPZ: 103566485(VDAC1)
EAI: 106834658(VDAC1) 106837945
MYB: 102249622(VDAC1)
MYD: 102758773(VDAC1)
MMYO: 118658112(VDAC1)
MLF: 102433336(VDAC1)
MDT: 132235649(VDAC1)
MYUM: 139010489(VDAC1)
PKL: 118710789(VDAC1)
EFUS: 103286741(VDAC1)
MNA: 107525398(VDAC1)
DRO: 112318103(VDAC1)
SHON: 118990086(VDAC1)
AJM: 119037617(VDAC1)
PDIC: 114509433(VDAC1)
PHAS: 123806839(VDAC1)
MMF: 118615375(VDAC1) 118627971
PPAM: 129066687(VDAC1)
HAI: 109382625(VDAC1)
RFQ: 117016684(VDAC1)
PALE: 102887036(VDAC1)
PGIG: 120581285(VDAC1)
PVP: 105293648(VDAC1)
RAY: 107506795(VDAC1)
MJV: 108410239(VDAC1)
TOD: 119243472(VDAC1)
SARA: 101557440(VDAC1)
SFUM: 130032919(VDAC1)
SETR: 126027768(VDAC1)
LAV: 100663098(VDAC1)
TMU: 101351096
ETF: 101653907 101656727(VDAC1)
DNM: 101413064(VDAC1)
MDO: 100014869(VDAC1)
GAS: 123237635(VDAC1)
SHR: 100927813(VDAC1)
AFZ: 127541140 127549828
PCW: 110211722(VDAC1)
TVP: 118843037(VDAC1)
PBRV: 138164218(VDAC1)
OAA: 100079428(VDAC1)
TACU: 119950105(VDAC1)
GGA: 416320(VDAC1)
PCOC: 116232222(VDAC1)
MGP: 100545075(VDAC1)
CJO: 107320177(VDAC1)
TPAI: 128083973(VDAC1)
LMUT: 125700064(VDAC1)
NMEL: 110405202(VDAC1)
APLA: 101803948(VDAC1)
ACYG: 106032765(VDAC1)
CATA: 118254955(VDAC1)
AFUL: 116494809(VDAC1)
TGU: 100222861(VDAC1)
LSR: 110481045(VDAC1)
SCAN: 103817251(VDAC1)
PMOA: 120498443(VDAC1)
OTC: 121332329(VDAC1)
PRUF: 121361380(VDAC1)
ATRC: 139597661(VDAC1)
GFR: 102038381(VDAC1)
FAB: 101813252(VDAC1)
OMA: 130258530(VDAC1)
PHI: 102099691(VDAC1)
PMAJ: 107210826(VDAC1)
CCAE: 111935601(VDAC1)
CCW: 104683723(VDAC1)
CBRC: 103614682(VDAC1)
ACOE: 138117962(VDAC1)
ETL: 114063907(VDAC1)
ZAB: 102062517(VDAC1)
ZLE: 135453647(VDAC1)
ACHL: 103805178(VDAC1)
SVG: 106862630(VDAC1)
MMEA: 130576574(VDAC1)
HRT: 120759241(VDAC1)
SATI: 136367425(VDAC1)
CCIC: 134049733(VDAC1)
FPG: 101912067(VDAC1)
FCH: 102046544(VDAC1)
CCRI: 104165718(VDAC1)
NNT: 104400318(VDAC1)
SHAB: 115615798(VDAC1)
ACUN: 113485107(VDAC1)
TALA: 104356148(VDAC1)
ACHC: 115334118(VDAC1)
HALD: 104317395(VDAC1)
HLE: 104838849(VDAC1)
AGEN: 126050941
HHAR: 128155086(VDAC1)
GCL: 127021995
CSTI: 104555616(VDAC1)
LDI: 104341010(VDAC1)
MNB: 103776450(VDAC1)
DPUB: 104309572(VDAC1)
PPUS: 135185450(VDAC1)
AVIT: 104268391(VDAC1)
BRHI: 104488324(VDAC1)
EGZ: 104133459(VDAC1)
NNI: 104012048(VDAC1)
PCRI: 104036645
PCAO: 104041387
PADL: 103915790(VDAC1)
AFOR: 103904440(VDAC1)
FGA: 104070955(VDAC1)
GSTE: 104256468(VDAC1)
CBOY: 140656652(VDAC1)
CLV: 102094843(VDAC1)
CNIC: 135993793(VDAC1)
MUI: 104534556(VDAC1)
PGUU: 104469646(VDAC1)
PLET: 104627724(VDAC1)
EHS: 104504117(VDAC1)
CMAC: 104483087(VDAC1)
CUCA: 104060671(VDAC1)
TEO: 104370592(VDAC1)
BREG: 104630389(VDAC1)
OHA: 104327482(VDAC1)
ACAR: 104518855(VDAC1)
CPEA: 104386851(VDAC1)
CVF: 104291600(VDAC1)
RTD: 128916292(VDAC1)
CRID: 134521981(VDAC1)
AAM: 106487263(VDAC1)
AROW: 112964883(VDAC1)
NPD: 112952833(VDAC1)
TGT: 104566678
DNE: 112994096(VDAC1)
SCAM: 104146920(VDAC1)
ASN: 102383593(VDAC1)
AMJ: 102575894(VDAC1)
CPOO: 109310087(VDAC1)
GGN: 109289963(VDAC1)
PSS: 102447058(VDAC1)
CMY: 102934893(VDAC1)
CCAY: 125641618(VDAC1)
DCC: 119859615(VDAC1)
CPIC: 101939936(VDAC1)
TST: 117881803(VDAC1)
CABI: 116826638(VDAC1)
MRV: 120370470(VDAC1)
ACS: 100567844(vdac1)
ASAO: 132768880(VDAC1)
PVT: 110079398(VDAC1)
SUND: 121922438(VDAC1)
PBI: 103048389(VDAC1)
PMUR: 107294898(VDAC1)
CTIG: 120305516(VDAC1)
TSR: 106542639(VDAC1)
PGUT: 117656120(VDAC1)
APRI: 131192056(VDAC1)
PTEX: 113433744(VDAC1)
NSS: 113425261(VDAC1)
VKO: 123035782(VDAC1)
PMUA: 114591267(VDAC1)
PRAF: 128407869(VDAC1)
ZVI: 118080354(VDAC1)
HCG: 128344742(VDAC1)
GJA: 107125981(VDAC1)
STOW: 125428464(VDAC1)
EMC: 129328145(VDAC1)
XLA: 108710805(vdac1.L) 380376(vdac1.S)
XTR: 549246(vdac1)
NPR: 108804463
ACAT: 141132418(VDAC1)
BBUF: 121009337(VDAC1)
BGAR: 122928267(VDAC1)
DTC: 141087916(VDAC1)
PWL: 138245532(VDAC1)
MUO: 115475936(VDAC1)
GSH: 117351691(VDAC1)
DRE: 334582(vdac1)
SRX: 107728276 107742456(vdac1)
SANH: 107661686(vdac1) 107692970
SGH: 107557296 107603230(vdac1)
CCAR: 109045441 109046102
CAUA: 113038197 113038198 113063836
CGIB: 127942244 127986097
PTET: 122326682(vdac1)
LROH: 127152760(vdac1)
GRF: 141292164(vdac1) 141292206
OMC: 131529251(vdac1)
PPRM: 120473681(vdac1)
RKG: 130096845(vdac1)
MAMB: 125252917(vdac1)
CIDE: 127504160
CERY: 137012328(vdac1)
MASI: 127429154 127430686
TROS: 130570444(vdac1)
TDW: 130408295(vdac1)
MANU: 129423740(vdac1)
PDAB: 135776735(vdac1)
PHYP: 113535684(vdac1)
SMEO: 124398206(vdac1)
AMEX: 103024199(vdac1)
CMAO: 118820044(vdac1)
EEE: 113578039(vdac1)
CHAR: 105893235(vdac1)
SPIL: 134079906(vdac1)
TRU: 101068401(vdac1)
TFS: 130537247(vdac1)
TNG: GSTEN00029888G001
LCO: 104931727(vdac1)
NCC: 104960858(vdac1)
TBEN: 117490425(vdac1)
CGOB: 115019093(vdac1)
PGEO: 117458719(vdac1)
GACU: 117540207(vdac1)
EMAC: 134872110(vdac1)
ELY: 117271469(vdac1)
EFO: 125898883(vdac1)
PLEP: 121952726(vdac1)
SLUC: 116056050(vdac1)
ECRA: 117955375(vdac1)
ESP: 116700318(vdac1)
PFLV: 114566908(vdac1)
GAT: 120821969(vdac1)
PPUG: 119215723(vdac1)
AFB: 129113161(vdac1)
CLUM: 117743293(vdac1)
PSWI: 130211260(vdac1)
CANA: 137802629(vdac1)
CVE: 137874236(vdac1)
MSAM: 119895609(vdac1)
SCHU: 122888510(vdac1)
CUD: 121519242(vdac1)
SPUL: 138597848(vdac1)
LMIX: 132988169(vdac1)
ALAT: 119031553(vdac1)
ASTR: 137606485(vdac1)
MZE: 101468605(vdac1)
ONL: 100696468(vdac1)
OAU: 116315794(vdac1)
OLA: 101173964(vdac1)
OML: 112142618(vdac1)
CSAI: 133460033(vdac1)
XMA: 102230604(vdac1)
XCO: 114152865(vdac1)
XHE: 116728559(vdac1)
PRET: 103475321(vdac1)
PFOR: 103152207 103155761(vdac1)
PLAI: 106937541 106938720
PMEI: 106916705(vdac1)
GAF: 122844688(vdac1)
PPRL: 129373421(vdac1)
CVG: 107085913(vdac1)
CTUL: 119797954(vdac1)
GMU: 124876828(vdac1)
NFU: 107386835(vdac1)
KMR: 108238016(vdac1)
ALIM: 106524568(vdac1)
NWH: 119420455(vdac1)
AOCE: 111566134(vdac1)
EJA: 138213609(vdac1)
BFRE: 138632229(vdac1)
MCEP: 125021054(vdac1)
CSEM: 103394861(vdac1)
POV: 109635867(vdac1)
SSEN: 122780041(vdac1)
SSOE: 131458822(vdac1)
HHIP: 117774288(vdac1)
HSP: 118122322(vdac1)
PPLT: 128457135(vdac1)
SMAU: 118300579(vdac1)
LCF: 108893817
SDU: 111234508(vdac1)
SLAL: 111659977(vdac1)
XGL: 120802729(vdac1)
HCQ: 109515682(vdac1)
SSCV: 125981904(vdac1)
SBIA: 133492085(vdac1)
PEE: 133416250(vdac1)
PTAO: 133467682(vdac1)
BPEC: 110153977(vdac1)
ENY: 140360730(vdac1)
MALB: 109966819(vdac1)
BSPL: 114869122(vdac1)
SJO: 128371447(vdac1)
SSCO: 133994025(vdac1)
GMH: 115546626(vdac1)
SASA: 106567523(VDAC1) 106603817(VDAC1)
STRU: 115148557 115154021
OTW: 112228201 112258095
OMY: 110533382 110537731
OGO: 123993129 124000382 124013725
ONE: 115105281 115136186
OKI: 109872931 109892953
OKE: 118389827 118390896
OMM: 135548832 135550948
OCLA: 139418038 139420786
SALP: 111981335 112069672
SNH: 120044390 120056891
CCLU: 121574006 121579233
ELS: 105026692(vdac1)
SFM: 108934477
PKI: 111839550 111847941
AANG: 118223048 118236558(vdac1)
AROT: 135250236 135262670(vdac1)
CCOG: 133123789 133132913(vdac1)
LOC: 102694412(vdac1)
PSPA: 121297542 121324665(vdac1)
ARUT: 117412959 117431171
PSEX: 120543172(vdac1)
LCM: 102350599(VDAC1)
CMK: 103183676(vdac1)
RTP: 109928316
CPLA: 122556581(vdac1)
HOC: 132823437(vdac1)
LERI: 129701805
HAKA: 140739157(vdac1)
AFLR: 105734832
OLG: 117605915
MGEN: 117220079
FAS: 105271542
AGIF: 122860769
VCAN: 122418139
PMEO: 129580995
 » show all
Reference
PMID:8420959
  Authors
Blachly-Dyson E, Zambronicz EB, Yu WH, Adams V, McCabe ER, Adelman J, Colombini M, Forte M
  Title
Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.
  Journal
J Biol Chem 268:1835-41 (1993)
  Sequence
[hsa:7416]
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