KEGG ORTHOLOGY: K08200

ORTHOLOGY: K08200

Entry

K08200                      KO

Symbol

SLC22A3, OCT3

Name

MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3

Pathway

map05231

Choline metabolism in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    K08200  SLC22A3, OCT3; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08200  SLC22A3, OCT3; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC22: Organic cation/anion/zwitterion transporter
   K08200  SLC22A3, OCT3; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
Major facilitator superfamily (MFS)
  Organic acid transporters
   Organic cation transporter (OCT) family
    K08200  SLC22A3, OCT3; MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3

Other DBs

GO:

0015101

TC:	2.A.1.19.6

Genes

HSA:	6581(SLC22A3)

PTR:	463114(SLC22A3)

PPS:	100968400(SLC22A3)

GGO:	101149506(SLC22A3)

PON:	100438264(SLC22A3)

PPYG:

129038249(SLC22A3)

NLE:	100601982(SLC22A3)

HMH:	116473601(SLC22A3)

SSYN:

129476207(SLC22A3)

MCC:	709454(SLC22A3)

MCF:	102147270(SLC22A3)

MTHB:

126953656

MNI:	105492006(SLC22A3)

CSAB:

103240837(SLC22A3)

CATY:

105581313(SLC22A3)

PANU:

101006621(SLC22A3)

TGE:	112622710(SLC22A3)

MLEU:

105536570(SLC22A3)

RRO:	104666415(SLC22A3)

RBB:	108516181(SLC22A3)

TFN:	117096918(SLC22A3)

PTEH:

111547261(SLC22A3)

CANG:

105506814(SLC22A3)

CJC:	100413296(SLC22A3)

SBQ:	101027990(SLC22A3)

CIMI:

108310846(SLC22A3)

ANAN:

105717684(SLC22A3)

CSYR:

103270362(SLC22A3)

MMUR:

105868603(SLC22A3)

LCAT:

123633436(SLC22A3)

PCOQ:

105812370(SLC22A3)

OGA:	100965948(SLC22A3)

MMU:	20519(Slc22a3)

MCAL:

110312599(Slc22a3)

MPAH:

110338252(Slc22a3)

RNO:	29504(Slc22a3)

MCOC:

116078476(Slc22a3)

ANU:	117700189(Slc22a3)

ASYL:

127674026(Slc22a3)

MUN:	110554864(Slc22a3)

CGE:	100763775(Slc22a3)

MAUA:

101826153(Slc22a3)

PROB:

127237695(Slc22a3)

PLEU:

114691366(Slc22a3)

MORG:

121466440(Slc22a3)

MFOT:

126497717

AAMP:

119820708

NGI:	103737007(Slc22a3)

HGL:	101704450(Slc22a3)

CPOC:

106026902(Slc22a3)

CCAN:

109685409

DORD:

105991799(Slc22a3)

DSP:	122116101(Slc22a3)

PLOP:

125357470(Slc22a3)

NCAR:

124989061

MMMA:

107153109(Slc22a3)

ITI:	101956930(Slc22a3)

OCU:	100008931(SLC22A3)

OPI:	101517438(SLC22A3)

TUP:	102499612(SLC22A3)

GVR:	103592018(SLC22A3)

CFA:	476261(SLC22A3)

CLUD:

112644399(SLC22A3)

VVP:	112932972(SLC22A3)

VLG:	121482055(SLC22A3)

NPO:	129499953(SLC22A3)

AML:	105238257(SLC22A3)

UMR:	103660827(SLC22A3)

UAH:	113259626(SLC22A3)

UAR:	123797542(SLC22A3)

ELK:

111158710

LLV:

125102242

MPUF:

101690155(SLC22A3)

MNP:	132018444(SLC22A3)

MLK:	131833395(SLC22A3)

NVS:	122902787(SLC22A3)

ORO:	101380494(SLC22A3)

EJU:	114209301(SLC22A3)

ZCA:	113926538(SLC22A3)

MLX:	118001785 118001907

NSU:	110583471(SLC22A3)

FCA:	101097728(SLC22A3)

PYU:	121013220(SLC22A3)

PCOO:

112862215(SLC22A3)

PBG:	122490156(SLC22A3)

PVIV:

125165489(SLC22A3)

LRUF:

124527960

LGF:	123609261(SLC22A3)

AJU:

106985033

PTG:	102962986(SLC22A3)

PPAD:

109245400(SLC22A3)

PLEZ:

122220570(SLC22A3)

HHV:	120224271(SLC22A3)

BTA:	535665(SLC22A3)

BOM:	102278905(SLC22A3)

BIU:	109563600(SLC22A3)

BBUB:

102411136(SLC22A3)

BBIS:

104989264(SLC22A3)

CHX:	102184436(SLC22A3)

OAS:	100642179(SLC22A3)

BTAX:

128053204(SLC22A3)

CSUM:

138089788(SLC22A3)

ODA:	120862824(SLC22A3)

CCAD:

122434050(SLC22A3)

MREE:

136163293(SLC22A3)

OVR:	110126584(SLC22A3)

MBEZ:

129561065(SLC22A3)

SSC:	100142677(SLC22A3)

CFR:	102510054(SLC22A3)

CBAI:

105077373(SLC22A3)

CDK:	105086289(SLC22A3)

VPC:	102525488(SLC22A3)

BACU:

103007698(SLC22A3)

BMUS:

118905242(SLC22A3)

LVE:	103076107(SLC22A3)

OOR:	101278011(SLC22A3)

LALB:

132530442(SLC22A3)

DLE:	111167671(SLC22A3)

PCAD:

102979670(SLC22A3)

PSIU:

116763500(SLC22A3)

NASI:

112401589(SLC22A3)

ECB:	100058287(SLC22A3)

EAI:	106842045(SLC22A3)

MYB:	102260224(SLC22A3)

MYD:	102774645(SLC22A3)

MMYO:

118660273(SLC22A3)

MLF:	102425522(SLC22A3)

MDT:	132236718(SLC22A3)

MYUM:

139012046(SLC22A3)

PKL:

118705878

EFUS:

103297952(SLC22A3)

MNA:	107535731(SLC22A3)

DRO:	112297160(SLC22A3)

SHON:

118995798(SLC22A3)

AJM:	119034914(SLC22A3)

PDIC:

114490098(SLC22A3)

PHAS:

123822167(SLC22A3)

MMF:	118621218(SLC22A3)

PPAM:

129088268(SLC22A3)

HAI:	109394016(SLC22A3)

RFQ:	117017322(SLC22A3)

PALE:

102878998(SLC22A3)

PGIG:

120617527(SLC22A3)

PVP:

105305673

RAY:	107514739(SLC22A3)

MJV:	108403114(SLC22A3)

TOD:	119253033(SLC22A3)

SARA:

101558119(SLC22A3)

SFUM:

130034555(SLC22A3)

SETR:

125996533(SLC22A3)

LAV:	100657671(SLC22A3)

TMU:

101343468

ETF:	101640260(SLC22A3)

DNM:	101432916(SLC22A3)

MDO:	100032482(SLC22A3)

GAS:	123246660(SLC22A3)

SHR:	100927691(SLC22A3)

AFZ:

127562392

PCW:	110208616(SLC22A3)

TVP:	118858618(SLC22A3)

PBRV:

138147795(SLC22A3)

OAA:	100084989(SLC22A3)

TACU:

119948098(SLC22A3)

GGA:	421582(SLC22A3)

PCOC:

116242053(SLC22A3)

MGP:

100548689

CJO:	107311525(SLC22A3)

TPAI:

128080947(SLC22A3)

LMUT:

125689963(SLC22A3)

NMEL:

110396036(SLC22A3)

APLA:

101793998(SLC22A3)

ACYG:

106039527(SLC22A3)

CATA:

118244073(SLC22A3)

AFUL:

116487952(SLC22A3)

TGU:

100226679

LSR:	110476010(SLC22A3)

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

139594239(SLC22A3)

GFR:	102036432(SLC22A3)

FAB:	101813101(SLC22A3)

OMA:	130251456(SLC22A3)

PHI:

102104324

PMAJ:

107202234

CCAE:

111927665

CCW:	104690412(SLC22A3)

CBRC:

103619332(SLC22A3)

ACOE:

138108286(SLC22A3)

ETL:

114055649

ZAB:	102061786(SLC22A3)

ZLE:	135445531(SLC22A3)

ACHL:

103801392(SLC22A3)

SVG:

106851922

MMEA:

130572610(SLC22A3)

HRT:	120750798(SLC22A3)

SATI:

136359110(SLC22A3)

CCIC:

134041838(SLC22A3)

FPG:	101922396(SLC22A3)

FCH:	102056113(SLC22A3)

CCRI:

104165642(SLC22A3)

NNT:	104408517(SLC22A3)

SHAB:

115613681

ACUN:

113478287(SLC22A3)

TALA:

104366056(SLC22A3)

ACHC:

115344329(SLC22A3)

HALD:

104320142

HLE:	104842259(SLC22A3)

AGEN:

126039049

HHAR:

128140657(SLC22A3)

GCL:

127015319

CSTI:

104560185(SLC22A3)

LDI:	104345504(SLC22A3)

MNB:

103773469

DPUB:

104307713(SLC22A3)

PPUS:

135183278(SLC22A3)

AVIT:

104276555

BRHI:

104499198(SLC22A3)

EGZ:	104124812(SLC22A3)

NNI:	104018095(SLC22A3)

PCRI:

104028613(SLC22A3)

PCAO:

104050069(SLC22A3)

PADL:

103918259(SLC22A3)

AFOR:

103907746(SLC22A3)

FGA:	104084432(SLC22A3)

GSTE:

104255953

CBOY:

140650081(SLC22A3)

CLV:	102089566(SLC22A3)

MUI:	104547737(SLC22A3)

PGUU:

104471364(SLC22A3)

PLET:

104620413(SLC22A3)

EHS:	104517250(SLC22A3)

CMAC:

104476802

CUCA:

104056464(SLC22A3)

TEO:	104375689(SLC22A3)

OHA:	104334700(SLC22A3)

ACAR:

104520733(SLC22A3)

CPEA:

104390788(SLC22A3)

CVF:	104295735(SLC22A3)

RTD:	128906935(SLC22A3)

CRID:

134513093(SLC22A3)

AAM:

106486787

AROW:

112966399(SLC22A3)

NPD:	112951962(SLC22A3)

TGT:	104573395(SLC22A3)

DNE:	112988962(SLC22A3)

SCAM:

104152831(SLC22A3)

ASN:	102377727(SLC22A3)

AMJ:	102573065(SLC22A3)

CPOO:

109320065(SLC22A3)

GGN:	109304823(SLC22A3)

PSS:	102446181(SLC22A3)

CMY:	102934716(SLC22A3)

CCAY:

125633994(SLC22A3)

DCC:	119853170(SLC22A3)

CPIC:

101945325(SLC22A3)

TST:	117874785(SLC22A3)

CABI:

116832460(SLC22A3)

MRV:	120402268(SLC22A3)

ACS:	100554856(slc22a3)

ASAO:

132761107

PVT:	110087385(SLC22A3)

SUND:

121921900(SLC22A3)

PBI:	103048013(SLC22A3)

PMUR:

107292069(SLC22A3)

CTIG:

120314802(SLC22A3)

TSR:	106548797(SLC22A3)

PGUT:

117672076(SLC22A3)

APRI:

131190834(SLC22A3)

PTEX:

113439287(SLC22A3)

NSS:	113417054(SLC22A3)

VKO:	123019121(SLC22A3)

PMUA:

114594309(SLC22A3)

PRAF:

128410719(SLC22A3)

ZVI:	118081957(SLC22A3)

HCG:	128344562(SLC22A3)

GJA:	107113337(SLC22A3)

STOW:

125438747(SLC22A3)

EMC:	129323638(SLC22A3)

NPR:	108794577(SLC22A3)

RTEM:

120937405

BBUF:

120998570(SLC22A3)

BGAR:

122934629(SLC22A3)

PWL:	138295961(SLC22A3)

MUO:	115466666(SLC22A3)

GSH:	117358143(SLC22A3)

DRE:	797890(slc22a3)

CCAR:

109106795(oct2)

CAUA:

113117725 113117790

CGIB:

127976310

PTET:

122362185(oct2)

LROH:

127180129(slc22a3)

OMC:	131523458(slc22a3)

RKG:	130088824(slc22a3)

MAMB:

125268332

CIDE:

127499030

CERY:

137006224 137006867

AMEX:

103033951(slc22a3)

CMAO:

118823658(oct2)

CHAR:

105895725(oct2)

SPIL:

134067607(slc22a3) 134075378

CGOB:

115006110

EMAC:

134881376(slc22a3)

ELY:	117267033 117267429

EFO:	125900590(slc22a3)

PLEP:

121954096(oct2)

AFB:	129103144(slc22a3)

CANA:

137788068(slc22a3)

CVE:	137880307(slc22a3)

CUD:	121526697(oct2)

SPUL:

138591746(slc22a3)

LMIX:

132993477(slc22a3)

ALAT:

119004554(oct2)

PFOR:

PLAI:

PMEI:

CVG:

CTUL:

119792801(oct2)

AOCE:

111578620(slc22a3)

EJA:	138205116(slc22a3)

BFRE:

138632272(slc22a3)

MCEP:

125023662(oct2)

LCF:

108886729

SDU:

111225555

SLAL:

111665813

XGL:	120795481(oct2)

HCQ:

109517309

SSCV:

125981135(slc22a3)

SBIA:

133513424(slc22a3)

PTAO:

133488218(slc22a3)

SJO:	128375921(slc22a3)

SSCO:

134000843(slc22a3)

STRU:

115162706

OMY:	110504242(oct2)

OGO:	124046976(oct2)

ONE:

115138760

OKE:	118369299(slc22a3)

OCLA:

139383783

SNH:	120023006(oct2)

CCLU:

121544288(oct2)

ELS:

105015417

OEP:	134026287(slc22a3)

SFM:	108920863 108921252

PKI:

111857864

LOC:	102691058 102691256

PSPA:

121315902

ARUT:

117402214 117403251

PSEX:

120525980

LCM:	102347944(SLC22A3)

CMK:	103176228 103181668

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:	133346900 133346967

ARUN:

117298613

AFIL:

140156068

PFLL:

139141452

DSI:	Dsimw501_GD15011(Dsim_GD15011)

DPO:

DPE:

DMN:

AAG:

ASUA:

ACER:

ALAB:

BBIF:

BVK:

BVAN:

BPYO:

MGEN:

CGIG:

SOC:

MPHA:

AEC:	105145574 105145620

ACEP:

PBAR:

VEM:

COBS:

TLN:

HST:	105181735 105181737 105181931 105185775

DQU:	106743042 106744496 106744497

CFO:	105257575 105257577

FEX:	115238333 115242077

PMEC:

138942376 138942377

LHU:

105669176

PGC:	109852927 109852928

OBO:	105283178 105283179

PCF:

VPS:

NVI:

CSOL:

MDL:	103573127 103576245 103576246

CGLO:

123272014

FAS:

105263226

DAM:

107041272

TCA:	654962 659137 661783

TMOL:

138135671 138135677 138135678 138135734

DPA:

ESIM:

EFOR:

ATD:

HAXR:

NVL:	108561479 108563608

BMOR:

101739567 101740637 101741063 101741290 101742978

BMAN:

114240320 114242331 114243758 114250004 114251892

DPL:	KGM_204748

PMAC:

106710218

BPHI:

137919018 137919019 137933764

HAW:	110370295 110370313 110370981 110373210 110381181 110382593

TNL:	113497900 113498251 113505936 113506774 113508277

ONU:	135073664 135076243 135078714

ATRA:

106134544 106135590 106138833

GMW:	113509698 113514178 113517929 113522326

PXY:

105386707

LGLY:

125229513 125230860

CSTB:

134744604 134746439 134747909

BTAB:

109036952 109042933

DCI:

103507381

CLEC:

106667770

PAME:

138705838 138705839 138708809

HAMR:

PCLA:

CQD:

PTRU:

ESN:	127003739 127004446

MNZ:	135195672 135212984

MRJ:	136838763 136853438

TCF:	131878783 131885261

PPOI:

RSAN:

RMP:

CVS:

ABRU:

PVUL:

BGT:	106066054 106069362

GAE:	121386806 121388910

HRJ:

HASI:

PMAX:

AIRR:

MAEA:

OSN:

LJP:

HSY:	130613909 130649314 130655359

RES:

135690658

CRE:	CHLRE_06g285300v5

VCN:	VOLCADRAFT_119010

» show all

Reference

PMID:10196521

Authors

Grundemann D, Schechinger B, Rappold GA, Schomig E

Title

Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter.

Journal

Nat Neurosci 1:349-51 (1998)
DOI:10.1038/1557

Sequence

[hsa:6581]

Reference

PMID:20103563

Authors

Klaassen CD, Aleksunes LM

Title

Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

Journal

Pharmacol Rev 62:1-96 (2010)
DOI:10.1124/pr.109.002014

LinkDB

DBGET integrated database retrieval system