Homo sapiens (human): 6581
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Entry
6581 CDS
T01001
Symbol
SLC22A3, EMT, EMTH, OCT3
Name
(RefSeq) solute carrier family 22 member 3
KO
K08200
MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa05231
Choline metabolism in cancer
Network
nt06544
Neuroactive ligand signaling
Element
N01912
Histamine metabolism and transport in neuron
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
6581 (SLC22A3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6581 (SLC22A3)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC22: Organic cation/anion/zwitterion transporter
6581 (SLC22A3)
Major facilitator superfamily (MFS)
Organic acid transporters
Organic cation transporter (OCT) family [TC:
2.A.1.19
]
6581 (SLC22A3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
6581
NCBI-ProteinID:
NP_068812
OMIM:
604842
HGNC:
10967
Ensembl:
ENSG00000146477
UniProt:
O75751
Structure
PDB
PDBj
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All DBs
Position
6:160348378..160452577
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AA seq
556 aa
AA seq
DB search
MPSFDEALQRVGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGTQPDHYWCRGPSAAALA
ERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLLEAANDSASATSALSCADPLAAFPNR
SAPLVPCRGGWRYAQAHSTIVSEFDLVCVNAWMLDLTQAILNLGFLTGAFTLGYAADRYG
RIVIYLLSCLGVGVTGVVVAFAPNFPVFVIFRFLQGVFGKGTWMTCYVIVTEIVGSKQRR
IVGIVIQMFFTLGIIILPGIAYFIPNWQGIQLAITLPSFLFLLYYWVVPESPRWLITRKK
GDKALQILRRIAKCNGKYLSSNYSEITVTDEEVSNPSFLDLVRTPQMRKCTLILMFAWFT
SAVVYQGLVMRLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGVA
CLVTAFLPEGIAWLRTTVATLGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFG
GIIAPFLLFRLAAVWLELPLIIFGILASICGGLVMLLPETKGIALPETVDDVEKLGSPHS
CKCGRNKKTPVSRSHL
NT seq
1671 nt
NT seq
+upstream
nt +downstream
nt
atgccctccttcgacgaggcgctgcagcgggtgggcgagttcgggcgcttccagaggcgc
gtgtttttgctgctgtgcctgacgggcgtcaccttcgccttcctcttcgtcggcgtggtc
ttcctgggcacgcagcccgaccactactggtgccgcgggccaagtgccgcggcgctggcc
gagcgctgcggctggagcccggaggaggagtggaaccgcacggcgcccgcctcccgcggc
ccagagccccccgagcgccgcggccgctgccagcgctacctcctggaggcggccaacgac
agcgcctccgccactagcgctctcagctgcgcggacccactcgccgccttccccaaccgc
tcggctccccttgtgccgtgccgcggcggctggcgctacgcccaggcccactccaccatc
gtcagcgagtttgaccttgtctgtgtcaatgcgtggatgctggacctcacccaagccatc
ctgaacctcggcttcctgactggagcattcaccttaggctatgcagcagacaggtatggc
aggatcgtcatttacttgctatcctgccttggtgttggcgtcactggggttgtggtggcc
tttgcaccaaacttccctgtgtttgtgatcttccgcttcctgcaaggtgtatttggaaag
gggacgtggatgacttgctacgtgattgtgacagaaatagtaggttcgaaacaaaggagg
attgtgggaatcgtgattcaaatgttctttacccttggaatcataattctccctggaatt
gcctacttcatccccaactggcaaggaatccagttagccatcacgctgcccagctttctc
ttcctcctttattactgggtggtccctgagtctccccgttggctgattactcggaagaaa
ggagataaagcattacagatcctgagacgcattgctaagtgcaatgggaaatacctctca
tcaaattactcagagatcactgttacagatgaggaagttagtaatccatcctttttagat
ctggtgagaactccccaaatgaggaaatgcacacttattcttatgtttgcttggttcaca
agcgcagtggtgtatcaaggacttgtcatgcgcctgggaattatagggggcaacctctat
atagactttttcatctcgggcgtggtggaactgccaggagctctcttgatcttactaacc
attgagcgccttggacgacgcctcccctttgcggcaagcaatatagtggcaggggtggca
tgccttgtcactgcgttcttaccagaaggaatagcatggttgaggaccacagtggctaca
ttgggaagactagggataaccatggcctttgaaattgtttatttggtaaattcagaattg
tacccaacaacattacgaaatttcggagtttcgctctgttcaggtctgtgtgattttggg
ggaatcatagccccatttctgctctttcggctagcagccgtgtggctagaactacctctg
atcatctttggtatcctggcatccatctgtggtggccttgtgatgcttttgcctgaaacc
aagggtattgccttgccagagacagtggatgatgtagaaaaacttggcagtccacattcc
tgtaaatgtggcaggaataagaaaaccccagtttcccgctctcacctttga
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