KEGG   ORTHOLOGY: K08748
Entry
K08748                      KO                                     
Symbol
SLC27A5, FATP5
Name
solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7]
Pathway
map00120  Primary bile acid biosynthesis
map01100  Metabolic pathways
map03320  PPAR signaling pathway
map04931  Insulin resistance
map04976  Bile secretion
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
M00106  Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate
Reaction
R02794  cholate:CoA ligase (AMP-forming)
R04507  3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)
R04580  3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)
R08733  3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming)
R08738  3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)
R08743  chenodeoxycholate:CoA ligase (AMP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
  09154 Digestive system
   04976 Bile secretion
    K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.7  cholate---CoA ligase
     K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC27: Fatty acid transporter
   K08748  SLC27A5, FATP5; solute carrier family 27 (fatty acid transporter), member 5
Other DBs
GO: 0004467 0005324 0047747 0015245
TC: 4.C.1.1.8
Genes
HSA: 10998(SLC27A5)
PTR: 456351(SLC27A5)
PPS: 100973518(SLC27A5)
GGO: 101141402(SLC27A5)
PON: 100450572(SLC27A5)
PPYG: 129020656(SLC27A5)
NLE: 100598523(SLC27A5)
HMH: 116479284(SLC27A5)
SSYN: 129460766(SLC27A5)
MCC: 713713(SLC27A5)
MCF: 102139611(SLC27A5)
MTHB: 126941889
MNI: 105488041(SLC27A5)
CSAB: 103235458(SLC27A5)
CATY: 105593284(SLC27A5)
PANU: 101012361(SLC27A5)
TGE: 112612525(SLC27A5)
MLEU: 105531198(SLC27A5)
RRO: 104680867(SLC27A5)
RBB: 108514368(SLC27A5)
TFN: 117091868(SLC27A5)
PTEH: 111530345(SLC27A5)
CANG: 105524030(SLC27A5)
CJC: 100394591(SLC27A5)
SBQ: 101033269(SLC27A5)
CIMI: 108289969(SLC27A5)
ANAN: 105731437(SLC27A5)
CSYR: 103262310(SLC27A5)
MMUR: 105864502(SLC27A5)
LCAT: 123624765(SLC27A5)
PCOQ: 105819607(SLC27A5)
OGA: 100943998(SLC27A5)
MMU: 26459(Slc27a5)
MCAL: 110297223(Slc27a5)
MPAH: 110336881(Slc27a5)
RNO: 79111(Slc27a5)
MCOC: 116101654(Slc27a5)
ANU: 117700681(Slc27a5)
MUN: 110562939(Slc27a5)
CGE: 100765567(Slc27a5)
MAUA: 101824762(Slc27a5)
PROB: 127238975(Slc27a5)
PLEU: 114703883(Slc27a5)
MORG: 121449385(Slc27a5)
MFOT: 126493814
AAMP: 119820463(Slc27a5)
NGI: 103725476(Slc27a5)
HGL: 101724180(Slc27a5)
CPOC: 100717817(Slc27a5)
CCAN: 109683037(Slc27a5)
DORD: 105994312(Slc27a5)
DSP: 122110673(Slc27a5)
PLOP: 125338761(Slc27a5)
NCAR: 124966722
MMMA: 107158986(Slc27a5)
OCU: 100340287
OPI: 101527096(SLC27A5)
TUP: 102483776(SLC27A5)
GVR: 103595548(SLC27A5)
CFA: 608675(SLC27A5)
CLUD: 112643327(SLC27A5)
VVP: 112908791(SLC27A5)
VLG: 121484156(SLC27A5)
NPO: 129500979(SLC27A5)
AML: 100478693(SLC27A5)
UMR: 103677216(SLC27A5)
UAH: 113248017(SLC27A5)
UAR: 123776624(SLC27A5)
ELK: 111139861
LLV: 125089011
MPUF: 101687342(SLC27A5)
MNP: 132005114(SLC27A5)
MLK: 131818144(SLC27A5)
NVS: 122912093(SLC27A5)
ORO: 101381954(SLC27A5)
EJU: 114200965(SLC27A5)
ZCA: 113936449(SLC27A5)
MLX: 117997921(SLC27A5)
NSU: 110581926(SLC27A5)
LWW: 102737843(SLC27A5)
FCA: 101086686(SLC27A5)
PYU: 121023395(SLC27A5)
PCOO: 112850703(SLC27A5)
PBG: 122494649(SLC27A5)
PVIV: 125152405(SLC27A5)
LRUF: 124522780
PTG: 102948587(SLC27A5)
PPAD: 109260425(SLC27A5)
PUC: 125915971
AJU: 106987933
HHV: 120227093(SLC27A5)
BTA: 533016(SLC27A5)
BOM: 102285844(SLC27A5)
BIU: 109571897(SLC27A5)
BBUB: 102396712(SLC27A5)
BBIS: 105001638(SLC27A5)
CHX: 102172839(SLC27A5)
OAS: 101120689(SLC27A5)
BTAX: 128063061(SLC27A5)
ODA: 120871847(SLC27A5)
CCAD: 122420603(SLC27A5)
MBEZ: 129546342(SLC27A5)
SSC: 102158419(SLC27A5)
CFR: 102519177(SLC27A5)
CBAI: 105074455(SLC27A5)
CDK: 105096797(SLC27A5)
VPC: 102538658(SLC27A5)
BACU: 103020672(SLC27A5)
BMUS: 118884939(SLC27A5)
LVE: 103086085(SLC27A5)
OOR: 101280268(SLC27A5)
DLE: 111170038(SLC27A5)
PCAD: 102979842(SLC27A5)
PSIU: 116744807(SLC27A5)
NASI: 112396914(SLC27A5)
ECB: 100051678(SLC27A5)
EPZ: 103567891(SLC27A5)
EAI: 106846663(SLC27A5)
MYB: 102261821(SLC27A5)
MYD: 102751593(SLC27A5)
MMYO: 118657417(SLC27A5)
MLF: 102425294(SLC27A5)
MDT: 132216415(SLC27A5)
PKL: 118712387(SLC27A5)
EFUS: 103304167(SLC27A5)
MNA: 107539367(SLC27A5)
DRO: 112313581(SLC27A5)
SHON: 118988175(SLC27A5)
AJM: 119051596(SLC27A5)
PDIC: 114511678(SLC27A5)
PHAS: 123825485(SLC27A5)
MMF: 118638221(SLC27A5)
PPAM: 129066277(SLC27A5)
HAI: 109377097(SLC27A5)
RFQ: 117034578(SLC27A5)
PALE: 102890200(SLC27A5)
PGIG: 120607133(SLC27A5)
PVP: 105308648(SLC27A5)
RAY: 107500402(SLC27A5)
MJV: 108408237(SLC27A5)
TOD: 119249800(SLC27A5)
SARA: 101552573(SLC27A5)
SETR: 126027979(SLC27A5)
LAV: 100676206(SLC27A5)
TMU: 101361902
ETF: 101643777(SLC27A5)
DNM: 101438816(SLC27A5)
MDO: 100029941(SLC27A5)
GAS: 123242899(SLC27A5)
SHR: 100916639(SLC27A5)
AFZ: 127556609
PCW: 110220184(SLC27A5)
TVP: 118838129(SLC27A5)
OAA: 100090562(SLC27A5)
LPIC: 129261741
RPHI: 132721510
 » show all
Reference
PMID:17495600
  Authors
Gimeno RE
  Title
Fatty acid transport proteins.
  Journal
Curr Opin Lipidol 18:271-6 (2007)
DOI:10.1097/MOL.0b013e3281338558
Reference
PMID:11980911
  Authors
Mihalik SJ, Steinberg SJ, Pei Z, Park J, Kim DG, Heinzer AK, Dacremont G, Wanders RJ, Cuebas DA, Smith KD, Watkins PA
  Title
Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling.
  Journal
J Biol Chem 277:24771-9 (2002)
DOI:10.1074/jbc.M203295200
  Sequence
[hsa:10998]
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