ORTHOLOGY: K09222
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Entry
K09222 KO
Symbol
REST
Name
RE1-silencing transcription factor
Pathway
map04550
Signaling pathways regulating pluripotency of stem cells
map05016
Huntington disease
Disease
H00604
Deafness, autosomal dominant
H01250
Hereditary gingival fibromatosis
H02301
Nephroblastoma
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
K09222 REST; RE1-silencing transcription factor
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
K09222 REST; RE1-silencing transcription factor
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors
K09222 REST; RE1-silencing transcription factor
03036 Chromosome and associated proteins
K09222 REST; RE1-silencing transcription factor
Transcription factors [BR:
ko03000
]
Eukaryotic type
Zinc finger
Cys2His2 others
K09222 REST; RE1-silencing transcription factor
Chromosome and associated proteins [BR:
ko03036
]
Eukaryotic type
Histone modification proteins
HDAC complexes
REST complex
K09222 REST; RE1-silencing transcription factor
BRITE hierarchy
Genes
HSA:
5978
(REST)
PTR:
471235
(REST)
PPS:
100968041
(REST)
GGO:
101143077
(REST)
PON:
100449247
(REST)
PPYG:
129034885
(REST)
NLE:
100583285
(REST)
HMH:
116467953
(REST)
SSYN:
129490990
(REST)
MCC:
100425257
(REST)
MCF:
102116020
(REST)
MTHB:
126955058
MNI:
105463564
(REST)
CSAB:
103235636
(REST)
CATY:
105575092
(REST)
PANU:
101007427
(REST)
TGE:
112624529
(REST)
MLEU:
105552715
(REST)
RRO:
104682704
(REST)
RBB:
108513477
(REST)
TFN:
117085569
(REST)
PTEH:
111526476
(REST)
CANG:
105508310
(REST)
CJC:
100399762
(REST)
SBQ:
101031593
(REST)
CIMI:
108292389
(REST)
ANAN:
105709275
(REST)
CSYR:
103265209
(REST)
MMUR:
105867870
(REST)
LCAT:
123624106
(REST)
PCOQ:
105807685
(REST)
OGA:
100941288
(REST)
MMU:
19712
(Rest)
MCAL:
110294391
(Rest)
MPAH:
110330594
(Rest)
RNO:
83618
(Rest)
MCOC:
116071321
(Rest)
ANU:
117713111
(Rest)
MUN:
110560331
(Rest)
CGE:
100756480
(Rest)
MAUA:
101829197
(Rest)
PROB:
127232485
(Rest)
PLEU:
114681291
(Rest)
114683244
114685189
114686832
114688288
114688292
114707604
114708181
114709275
MORG:
121460801
(Rest)
MFOT:
126506422
AAMP:
119814381
(Rest)
NGI:
103734374
(Rest)
HGL:
101718905
(Rest)
CPOC:
100729177
(Rest)
CCAN:
109691663
(Rest)
DORD:
105980282
(Rest)
DSP:
122106774
(Rest)
PLOP:
125364421
(Rest)
NCAR:
124994664
MMMA:
107139256
(Rest)
OCU:
100341801
OPI:
101533757
(REST)
TUP:
102488680
(REST)
GVR:
103594630
(REST)
CFA:
100682666
482163
(REST)
CLUD:
112652141
(REST)
VVP:
112923703
(REST)
VLG:
121473518
(REST)
NPO:
129520498
(REST)
AML:
100483588
(REST)
UMR:
103672754
(REST)
UAH:
113262528
(REST)
UAR:
123804029
(REST)
ELK:
111149307
LLV:
125093757
MPUF:
101691035
(REST)
MNP:
132006620
(REST)
MLK:
131823748
(REST)
NVS:
122890154
(REST)
ORO:
101384761
(REST)
EJU:
114206780
(REST)
ZCA:
113924784
(REST)
MLX:
118010499
(REST)
NSU:
110590822
(REST)
LWW:
102749433
(REST)
FCA:
101086719
(REST)
PYU:
121035201
(REST)
PCOO:
112858420
(REST)
PBG:
122497300
(REST)
PVIV:
125164155
(REST)
LRUF:
124520215
PTG:
102949845
(REST)
PPAD:
109278581
(REST)
PUC:
125922753
AJU:
106971663
HHV:
120243036
(REST)
BTA:
507148
(RESTB)
615792
(RESTA)
BOM:
102273989
102278808
102279088
(REST)
BIU:
109560498
109560500
BBUB:
102396779
(REST)
102398050
BBIS:
105002820
105002870
CHX:
102180114
102181107
OAS:
101110593
(REST)
101111099
BTAX:
128049740
128049791
ODA:
120862155
120862156
CCAD:
122428082
122428174
MREE:
136152639
(REST)
136152661
MBEZ:
129561574
129561816
SSC:
100520754
(REST)
100621006
CFR:
102506327
102517836
(REST)
CBAI:
105077687
105078873
CDK:
105091557
105102812
116151515
VPC:
102526304
102538543
(REST)
BACU:
103006127
(REST)
103007708
103008872
BMUS:
118895580
118895754
LVE:
103078260
(REST)
103090669
OOR:
101274536
101285771
101286016
DLE:
111169240
(REST)
111169295
PCAD:
102994369
102995069
112063355
PSIU:
116754328
(REST)
116754783
ECB:
100058152
(REST)
EPZ:
103556481
(REST)
EAI:
106841687
(REST)
MYB:
102261820
(REST)
MYD:
102755535
(REST)
MMYO:
118669148
(REST)
MLF:
102435343
(REST)
MDT:
132218684
(REST)
PKL:
118706111
(REST)
EFUS:
103285053
(REST)
MNA:
107533240
(REST)
DRO:
112322213
(REST)
SHON:
118978573
(REST)
AJM:
119061643
(REST)
PDIC:
114492845
(REST)
PHAS:
123815689
(REST)
MMF:
118627506
(REST)
PPAM:
129065532
(REST)
HAI:
109394382
(REST)
RFQ:
117022365
(REST)
PALE:
102879115
(REST)
PGIG:
120588111
(REST)
PVP:
105293757
(REST)
RAY:
107517714
(REST)
MJV:
108387770
(REST)
TOD:
119260657
(REST)
SARA:
101551510
(REST)
SETR:
126032274
(REST)
LAV:
100659269
(REST)
TMU:
101345477
ETF:
101647109
(REST)
DNM:
101433509
(REST)
MDO:
100016000
(REST)
GAS:
123251263
(REST)
SHR:
100921808
(REST)
AFZ:
127539922
PCW:
110200152
(REST)
TVP:
118854482
(REST)
PBRV:
138175035
(REST)
OAA:
100078457
(REST)
GGA:
422623
(REST)
PCOC:
116231143
(REST)
MGP:
100549206
(REST)
CJO:
107313403
(REST)
TPAI:
128080603
(REST)
LMUT:
125692585
(REST)
NMEL:
110399054
(REST)
APLA:
101791754
(REST)
ACYG:
106046092
(REST)
CATA:
118247341
(REST)
AFUL:
116488744
(REST)
TGU:
100228357
(REST)
LSR:
110471704
(REST)
SCAN:
103825985
(REST)
PMOA:
120502716
(REST)
OTC:
121348411
(REST)
PRUF:
121360218
(REST)
GFR:
102031873
(REST)
FAB:
101814797
(REST)
OMA:
130252510
(REST)
PHI:
102099605
(REST)
PMAJ:
107203260
(REST)
CCAE:
111927808
(REST)
CCW:
104697147
(REST)
CBRC:
103617346
(REST)
ETL:
114065781
(REST)
ZAB:
102074943
(REST)
ZLE:
135446760
(REST)
ACHL:
103808367
(REST)
SVG:
106860444
(REST)
MMEA:
130579653
(REST)
HRT:
120752812
(REST)
SATI:
136360478
(REST)
FPG:
101911619
(REST)
FCH:
102054905
(REST)
CCRI:
104165217
(REST)
NNT:
104404393
(REST)
SHAB:
115610936
(REST)
ACUN:
113479642
(REST)
TALA:
104366110
(REST)
ACHC:
115342737
(REST)
HALD:
104314050
(REST)
HLE:
104843293
(REST)
AGEN:
126044628
GCL:
127015745
CSTI:
104549774
(REST)
LDI:
104350003
(REST)
MNB:
103769602
(REST)
DPUB:
104298085
(REST)
PPUS:
135178076
(REST)
AVIT:
104267678
(REST)
BRHI:
104488061
(REST)
EGZ:
104122668
(REST)
NNI:
104021209
(REST)
PCRI:
104031607
(REST)
PCAO:
104046951
(REST)
PADL:
103921756
(REST)
AFOR:
103902264
(REST)
FGA:
104075593
(REST)
GSTE:
104258812
(REST)
CLV:
102087713
(REST)
MUI:
104533534
(REST)
PGUU:
104470156
(REST)
PLET:
104622406
(REST)
EHS:
104502924
(REST)
CMAC:
104477352
(REST)
CUCA:
104064987
(REST)
TEO:
104369889
(REST)
BREG:
104629401
(REST)
OHA:
104331693
(REST)
ACAR:
104517876
(REST)
CPEA:
104387177
(REST)
CVF:
104294108
(REST)
RTD:
128910160
(REST)
AAM:
106495841
(REST)
AROW:
112973799
(REST)
NPD:
112953428
(REST)
TGT:
104580659
(REST)
DNE:
112989310
(REST)
SCAM:
104149853
(REST)
ASN:
102378229
(REST)
AMJ:
102565143
(REST)
CPOO:
109309455
(REST)
GGN:
109301254
(REST)
PSS:
102445246
(REST)
CMY:
102941140
(REST)
CCAY:
125635319
(REST)
DCC:
119854715
(REST)
CPIC:
101947249
(REST)
TST:
117877739
(REST)
CABI:
116826337
(REST)
MRV:
120406520
(REST)
ACS:
100564403
(rest)
ASAO:
132767579
(REST)
PVT:
110091002
(REST)
SUND:
121922122
(REST)
PBI:
103055825
(REST)
PMUR:
107285624
107286919
CTIG:
120308760
(REST)
TSR:
106550815
(REST)
PGUT:
117661754
(REST)
APRI:
131191578
(REST)
PTEX:
113444076
(REST)
NSS:
113426104
(REST)
VKO:
123017488
(REST)
PMUA:
114587605
(REST)
PRAF:
128405281
(REST)
ZVI:
118075429
(REST)
HCG:
128345146
(REST)
GJA:
107106832
(REST)
STOW:
125436234
(REST)
EMC:
129334355
(REST)
XLA:
373614
(rest.S)
734238
(rest.L)
XTR:
734016
(rest)
NPR:
108799561
108802630
RTEM:
120912027
(REST)
BBUF:
120989636
(REST)
BGAR:
122927806
(REST)
MUO:
115463788
115463791
(REST)
GSH:
117345995
(REST)
DRE:
564772
(rest)
SRX:
107750328
107751319
(rest)
SANH:
107677370
107697616
SGH:
107562372
(rest)
107587061
CCAR:
109046467
109047204
CAUA:
113057639
113113843
CGIB:
127971983
128027618
PTET:
122357491
(rest)
LROH:
127175809
(rest)
OMC:
131553377
(rest)
PPRM:
120460768
(rest)
RKG:
130072483
(rest)
MAMB:
125259105
(rest)
CIDE:
127525657
CERY:
137023099
(rest)
MASI:
127412630
127417587
TROS:
130563623
(rest)
TDW:
130438169
(rest)
MANU:
129421995
(rest)
IPU:
108275113
IFU:
128623385
(rest)
PHYP:
113539864
(rest)
SMEO:
124397219
(rest)
TFD:
113648374
(rest)
TVC:
132861209
(rest)
TRN:
134336081
(rest)
AMEX:
103034010
(rest)
CMAO:
118821126
(rest)
EEE:
113587934
(rest)
CHAR:
105888599
(rest)
TRU:
100216471
(rest)
115246415
TFS:
130531443
(rest)
TNG:
GSTEN00012073G001
LCO:
104936076
(rest)
NCC:
104968113
(rest)
TBEN:
117482569
(rest)
EMAC:
134859603
(rest)
ELY:
117269473
(rest)
EFO:
125894366
(rest)
PLEP:
121947939
(rest)
SLUC:
116060259
(rest)
ECRA:
117941476
(rest)
PFLV:
114562962
(rest)
GAT:
120817302
(rest)
PPUG:
119211448
(rest)
AFB:
129089932
(rest)
CLUM:
117737598
(rest)
PSWI:
130210582
(rest)
CANA:
137804808
(rest)
CVE:
137875084
(rest)
MSAM:
119888326
(rest)
SCHU:
122880512
(rest)
CUD:
121516322
(rest)
ALAT:
119007281
(rest)
ASTR:
137602535
(rest)
MZE:
101472807
(rest)
ONL:
100693239
(rest)
OAU:
116332058
(rest)
OLA:
101171397
(rest)
OML:
112153209
(rest)
CSAI:
133446708
(rest)
XMA:
102216701
(rest)
XCO:
114139602
(rest)
XHE:
116714589
(rest)
PRET:
103471787
(rest)
PFOR:
103155974
(rest)
PLAI:
106958579
PMEI:
106922897
GAF:
122836754
(rest)
PPRL:
129354329
129360292
CVG:
107082720
(rest)
CTUL:
119784562
(rest)
GMU:
124860125
(rest)
NFU:
107381113
(rest)
KMR:
108228877
(rest)
ALIM:
106534158
(rest)
NWH:
119408815
(rest)
AOCE:
111570938
(rest)
MCEP:
125008281
(resT)
CSEM:
103390793
(rest)
POV:
109645180
SSEN:
122778192
(rest)
HHIP:
117769182
(rest)
HSP:
118112099
(rest)
PPLT:
128445457
(rest)
SMAU:
118320055
(rest)
LCF:
108885295
SDU:
111233497
(rest)
SLAL:
111665592
XGL:
120785453
(rest)
HCQ:
109508297
(rest)
SSCV:
125979249
(rest)
SBIA:
133508412
(rest)
PEE:
133407967
(rest)
PTAO:
133484614
(rest)
BPEC:
110168020
(rest)
MALB:
109951107
(rest)
BSPL:
114864570
(rest)
SJO:
128363281
(rest)
SASA:
106604639
106611646
STRU:
115171569
115205176
OTW:
112220986
112256272
OMY:
110488856
110505059
OGO:
123993443
124010566
ONE:
115129491
115130738
OKI:
109864788
109905221
OKE:
118363531
118378569
SALP:
111965772
111967525
SNH:
120048080
120062282
CCLU:
121541947
ELS:
105007536
(rest)
SFM:
108938792
(rest)
PKI:
111848741
(rest)
AANG:
118228272
118231894
(rest)
LOC:
102693544
(rest)
PSPA:
121294877
(rest)
121323258
ARUT:
117408641
117421273
PSEX:
120532262
(rest)
LCM:
102347070
102365460
(REST)
CMK:
103182119
(rest)
RTP:
125481013
CPLA:
122564880
(rest)
HOC:
132825336
(rest)
LERI:
129695584
(rest)
BFO:
118413327
BBEL:
109467264
109467267
109467438
109471125
AGB:
108914438
LDC:
111517959
VJA:
111273738
» show all
Taxonomy
UniProt
Reference
PMID:
7697725
Authors
Chong JA, Tapia-Ramirez J, Kim S, Toledo-Aral JJ, Zheng Y, Boutros MC, Altshuller YM, Frohman MA, Kraner SD, Mandel G
Title
REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons.
Journal
Cell 80:949-57 (1995)
DOI:
10.1016/0092-8674(95)90298-8
Sequence
[hsa:
5978
]
Reference
PMID:
8568247
Authors
Scholl T, Stevens MB, Mahanta S, Strominger JL
Title
A zinc finger protein that represses transcription of the human MHC class II gene, DPA.
Journal
J Immunol 156:1448-57 (1996)
Sequence
[hsa:
5978
]
LinkDB
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