KEGG   ORTHOLOGY: K09827
Entry
K09827                      KO                                     
Symbol
ERG27
Name
3-keto steroid reductase [EC:1.1.1.270]
Pathway
map00100  Steroid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Reaction
R07495  4alpha-methylzymosterol:NADP+ 3-oxidoreductase
R12405  zymosterol:NADP+ 3-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K09827  ERG27; 3-keto steroid reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase
     K09827  ERG27; 3-keto steroid reductase
Other DBs
COG: COG1028
GO: 0050576
Genes
SCE: YLR100W(ERG27)
SEUB: DI49_3627
SPAO: SPAR_L01540
AGO: AGOS_AGR068W
ERC: Ecym_4279
KLA: KLLA0_F19756g
KMX: KLMA_40163(ERG27)
LTH: KLTH0G13046g
VPO: Kpol_1033p20
ZRO: ZYRO0D06534g
CGR: 2891410(GVI51_M11473)
NCS: NCAS_0B03680(NCAS0B03680) NCAS_0B05180(NCAS0B05180)
NDI: NDAI_0B02550(NDAI0B02550) NDAI_0J01100(NDAI0J01100)
TPF: TPHA_0C01040(TPHA0C01040)
TBL: TBLA_0D04010(TBLA0D04010)
TGB: HG536_0C01650
TDL: TDEL_0F04160(TDEL0F04160)
KAF: KAFR_0B02860(KAFR0B02860) KAFR_0B05590(KAFR0B05590)
KNG: KNAG_0G02190(KNAG0G02190) KNAG_0I01040(KNAG0I01040)
ZMK: HG535_0G04170
DHA: DEHA2E20130g
PIC: PICST_61325(ERG27)
PGU: PGUG_05066
SPAA: SPAPADRAFT_59939
LEL: PVL30_000153(ERG27)
LBG: 92206133(LODBEIA_P09370)
CAL: CAALFM_CR01140CA(ERG27)
CTP: CTRG_00974
COT: CORT_0A01630
CDU: CD36_26140(ERG27)
CTEN: 18246800(ERG27)
CLU: CLUG_05409
CLUS: A9F13_23g00473
CAUR: CJI96_0005271
ASAU: 88174641(PUMCH_003578)
PPA: PAS_chr2-1_0628
PKZ: C5L36_0A05120
BNN: FOA43_001771
BBRX: BRETT_004734
OPA: HPODL_01047
YLI: 2907211(YALI2_C00731g)
SLB: AWJ20_1569(ERG27)
NCR: NCU05991
NTE: NEUTE1DRAFT69544(NEUTE1DRAFT_69544)
SMP: 10808170(SMAC4_07919)
PAN: PODANSg3046
PBEL: QC761_408110(ERG27)
PPSD: QC762_408110(ERG27)
PPSP: QC763_408110(ERG27)
PPSA: QC764_408110(ERG27)
TTT: THITE_164350
MTM: MYCTH_69410
CTHR: CTHT_0040790
RTHE: 98126814(VTJ83DRAFT_5557)
MGR: MGG_01303
PPEI: PpBr36_00814
PGRI: PgNI_04229
TMN: UCRPA7_4666
SSCK: SPSK_07425
FGR: FGSG_13596
FPU: FPSE_10479
FPOA: FPOAC1_012172
FVN: FVRRES_13250
FVR: FVEG_04041
FOX: FOXG_06186
NHE: NECHADRAFT_91272
FFC: NCS54_00293900
FKR: NCS57_00289300
FMU: J7337_004046
TRE: TRIREDRAFT_2634
TRR: M419DRAFT_72950
TATV: 25777598(TrAtP1_013352)
TASP: 36614338(TrAFT101_007732)
MAW: 19246994(ERG27)
MAJ: MAA_02120
MBRN: 26239690(ERG27)
PCHM: VFPPC_01571
CMT: CCM_05105
AMUS: LMH87_010992
PLJ: 28886101(PLICBS_007603)
PTKZ: JDV02_004553(ERG27)
VAL: VDBG_08048
VDA: VDAG_01545
CFJ: CFIO01_12216
CLUP: CLUP02_00244
CHIG: CH63R_08186
CDET: 87945424(CDEST_08921)
SAPO: SAPIO_CDS8162
ELA: UCREL1_2995
PFY: PFICI_14173
SSL: SS1G_00326
BFU: BCIN_03g05110
MBE: MBM_01041
PSCO: LY89DRAFT_608282
GLZ: GLAREA_07003
ANI: ANIA_05585
AFM: AFUA_4G11500
ACT: ACLA_050580
NFI: NFIA_104700
AOR: AO090003001070
ANG: An04g05000
AFV: AFLA_000602
ALUC: AKAW2_51484A(ERG27)
ACHE: ACHE_10583S(ERG27)
APUU: APUU_40944S(ERG27)
PCS: N7525_005626
PDP: PDIP_33960
POU: POX_a01511
TMF: EYB26_005378
TRG: TRUGW13939_02849
CIM: CIMG_01575
CPW: 9691136(ERG27)
URE: UREG_05299
ABE: ARB_02354
TVE: TRV_04668
PBL: PAAG_02717
PBN: PADG_01744
AJE: HCAG_01553
BGH: BDBG_07225
PNO: SNOG_06194
PTE: PTT_11743
PTRR: 6340880(PtrM4_062250)
BZE: COCCADRAFT_22878
BSC: COCSADRAFT_32948
BOR: COCMIDRAFT_4981
AALT: CC77DRAFT_76456
ADAC: 96082283(ACET3X_001961)
ARAB: EKO05_0005817
ZTR: MYCGRDRAFT_38293
PFJ: MYCFIDRAFT_82835
FFU: CLAFUR5_04846 CLAFUR5_06261
CBET: CB0940_08812
NPA: UCRNP2_3103
TML: GSTUM_00003619001
SPO: 2540195(erg27)
SOM: SOMG_01374(erg27)
CNE: CND03020
CNB: CNBD3330
CNG: CNAG_07437
CGI: CGB_D5570C
CDEU: CNBG_0746
CDEP: 91084397(L203_100181)
KMG: 30166604(I203_100674)
KNE: 92181633(IAR55_004375)
TMS: TREMEDRAFT_43600
TASA: A1Q1_03186
CCAC: CcaHIS019_0101450(ERG27)
TVS: TRAVEDRAFT_73290
DSQ: DICSQDRAFT_162108 DICSQDRAFT_88133
HIR: HETIRDRAFT_312795
ADL: AURDEDRAFT_80749
FME: FOMMEDRAFT_21336
GTR: GLOTRDRAFT_103653
RSX: RhiXN_04275
LBC: LACBIDRAFT_303734
CCI: CC1G_09970
ABP: AGABI1DRAFT79443(AGABI1DRAFT_79443)
ABV: AGABI2DRAFT202140(AGABI2DRAFT_202140)
MRR: Moror_13823
MORE: E1B28_007285
SCM: SCHCO_02624672(SCHCODRAFT_02624672)
CPUT: CONPUDRAFT_103632
SLA: SERLADRAFT_333162
WSE: WALSEDRAFT_70726
UMA: UMAG_02895
PFP: PFL1_04973
MGL: MGL_2564
MRT: MRET_0524
PGR: PGTG_14396
PTRC: PtA15_8A46
PSTR: Pst134EA_015010
MLR: MELLADRAFT_64276
 » show all
Reference
PMID:10535978
  Authors
Gachotte D, Sen SE, Eckstein J, Barbuch R, Krieger M, Ray BD, Bard M
  Title
Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation.
  Journal
Proc Natl Acad Sci U S A 96:12655-60 (1999)
DOI:10.1073/pnas.96.22.12655
  Sequence
[sce:YLR100W]
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