KEGG   REACTION: R12405
Entry
R12405                      Reaction                               
Name
zymosterol:NADP+ 3-oxidoreductase
Definition
Zymosterone + NADPH + H+ <=> Zymosterol + NADP+
Equation
C22136 + C00005 + C00080 <=> C05437 + C00006
Reaction class
RC00144  C05437_C22136
Enzyme
1.1.1.270
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00101  Cholesterol biosynthesis, FPP => cholesterol
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.270
     R12405  Zymosterone + NADPH + H+ <=> Zymosterol + NADP+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.270
   R12402  3beta-Hydroxysteroid <=> 3-Oxosteroid
    R12405  Zymosterol <=> Zymosterone
Orthology
K09827  3-keto steroid reductase [EC:1.1.1.270]
K13373  17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
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