KEGG   ORTHOLOGY: K11153
Entry
K11153                      KO                                     

Symbol
RDH12
Name
retinol dehydrogenase 12 [EC:1.1.1.300]
Pathway
map00830  Retinol metabolism
map01100  Metabolic pathways
map01240  Biosynthesis of cofactors
Disease
H00837  Leber congenital amaurosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K11153  RDH12; retinol dehydrogenase 12
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.300  NADP-retinol dehydrogenase
     K11153  RDH12; retinol dehydrogenase 12
Other DBs
RN: R08379 R08383
GO: 0052650
Genes
HSA: 145226(RDH12)
PTR: 100615509(RDH12)
PPS: 100976717(RDH12)
GGO: 101133959(RDH12)
PON: 100444779(RDH12)
NLE: 100592081(RDH12)
MCC: 711438(RDH12)
MCF: 101865597(RDH12)
CSAB: 103229215(RDH12)
CATY: 105582867(RDH12)
PANU: 101000507(RDH12)
RRO: 104664937(RDH12)
RBB: 108533722(RDH12)
TFN: 117069432(RDH12)
PTEH: 111520011(RDH12)
CJC: 100403102(RDH12)
SBQ: 101033448(RDH12)
MMUR: 105880251(RDH12)
MMU: 77974(Rdh12)
MCAL: 110307230(Rdh12)
MPAH: 110324761(Rdh12)
RNO: 314264(Rdh12)
MCOC: 116079825(Rdh12)
CGE: 100759583(Rdh12)
PLEU: 114697775(Rdh12)
NGI: 103749298(Rdh12)
HGL: 101715642(Rdh12)
CCAN: 109694522(Rdh12)
OCU: 100337836(RDH12)
TUP: 102498963(RDH12)
CFA: 490744(RDH12)
VVP: 112927128(RDH12)
VLG: 121493408(RDH12)
AML: 100468936(RDH12)
UMR: 103671847(RDH12)
ORO: 101366366(RDH12)
ELK: 111148666
MPUF: 101672924(RDH12)
EJU: 114207585(RDH12)
MLX: 118002451(RDH12)
FCA: 101093615(RDH12)
PYU: 121031951(RDH12)
PBG: 122469250(RDH12)
PTG: 102958225(RDH12)
PPAD: 109268278(RDH12)
AJU: 106971559(RDH12)
HHV: 120237433(RDH12)
BTA: 369021(RDH12)
BOM: 102271090(RDH12)
BIU: 109564569(RDH12)
BBUB: 102405382(RDH12)
CHX: 102173010(RDH12)
OAS: 101115797(RDH12)
ODA: 120852789(RDH12)
CCAD: 122443782(RDH12)
SSC: 100153020(RDH12)
CFR: 102516964(RDH12)
CBAI: 105074699(RDH12)
CDK: 105086164(RDH12)
BACU: 103009435(RDH12)
LVE: 103090972(RDH12)
OOR: 101283442(RDH12)
DLE: 111173259(RDH12)
PCAD: 102978048(RDH12)
ECB: 100063369(RDH12)
EPZ: 103541139(RDH12)
EAI: 106844772(RDH12)
MYB: 102260844(RDH12)
MYD: 102764631(RDH12)
MMYO: 118656932(RDH12)
MNA: 107545710(RDH12)
HAI: 109382038(RDH12)
DRO: 112311390(RDH12)
SHON: 118976801(RDH12)
AJM: 119034816(RDH12)
MMF: 118628335(RDH12)
PALE: 102886424(RDH12)
PGIG: 120612772(RDH12)
RAY: 107503281(RDH12)
MJV: 108410078(RDH12)
TOD: 119239214(RDH12)
LAV: 100659620(RDH12)
TMU: 101358377
MDO: 100028379(RDH12)
SHR: 100923904
PCW: 110220578(RDH12)
GGA: 423274(RDH12)
PCOC: 116229291
MGP: 100540846
CJO: 107314931
NMEL: 110401302
APLA: 101793409
ACYG: 106031772
TGU: 100226769
LSR: 110473996
SCAN: 103826955
PMOA: 120500308
GFR: 102032925(RDH12)
FAB: 101816060(RDH12)
PHI: 102106104(RDH12)
PMAJ: 107205238
CCAE: 111930091
CCW: 104688342
ETL: 114062535
FPG: 101916630(RDH12)
FCH: 102055890
EGZ: 104122065
NNI: 104020414
ACUN: 113480412
PADL: 103914367
AAM: 106483104(RDH12)
AROW: 112974997
NPD: 112946384
DNE: 112980747
ASN: 102373718
AMJ: 102567292(RDH12)
CPOO: 109321084
GGN: 109298864
PSS: 102446647
CMY: 102934533
CPIC: 101950060
TST: 117876877
CABI: 116821488
PBI: 103055029
PMUR: 107285841
TSR: 106544503
PGUT: 117665566
GJA: 107112214(RDH12)
DRE: 100141353(si:dkey-94e7.2) 100150965(si:dkey-73n8.3) 407663(si:ch211-107o10.3) 436597(rdh12) 494176(rdh12l) 553712(zgc:112332) 561542(si:dkey-23o4.6) 751745(zgc:153441)
ELY: 117259970(si:ch211-107o10.3) 117262711 117264433(rdh12l) 117264561(zgc:112332) 117264898(si:dkey-73n8.3) 117266286 117267571(rdh12)
PLEP: 121949987 121953459(rdh12) 121960539(rdh12l) 121960599(si:dkey-73n8.3) 121960618(zgc:112332) 121961810(si:ch211-107o10.3)
SLUC: 116037906(zgc:112332) 116038040(si:dkey-73n8.3) 116048580(rdh12l) 116057432(rdh12) 116060464(si:ch211-107o10.3) 116062588
ECRA: 117935682(rdh12) 117937551(si:dkey-73n8.3) 117937552(zgc:112332) 117937796(rdh12l) 117948795(si:ch211-107o10.3)
GAT: 120810131 120810820(si:ch211-107o10.3) 120811541 120811542 120811951(rdh12l) 120832957(rdh12)
MSAM: 119883128(si:dkey-73n8.3) 119887132 119890531(si:ch211-107o10.3) 119893944 119898234 119908538(zgc:112332) 119909958(rdh12)
CUD: 121509965(si:ch211-107o10.3) 121513629 121515322 121525814(rdh12) 121526968 121527289 121527325(zgc:112332) 121527476(si:dkey-73n8.3)
OAU: 116310336 116310351 116314699(si:ch211-107o10.3) 116315244(rdh12) 116326232 116327119 116328260(si:dkey-73n8.3) 116328286(zgc:112332)
OML: 112136602 112147772(rdh12) 112151630(rdh12l) 112152847(si:ch211-107o10.3)
CTUL: 119772479 119780930 119784614(si:dkey-73n8.3) 119784615(zgc:112332) 119794956(rdh12) 119797373 119798413(rdh12l)
KMR: 108228975 108230029 108230278(rdh12l) 108232585(rdh12) 108237291(si:ch211-107o10.3) 108243166(si:dkey-73n8.3) 108243167(zgc:112332)
XGL: 120784530 120789703(si:dkey-73n8.3) 120789704(zgc:112332) 120789809(rdh12l) 120791156(si:ch211-107o10.3) 120793779 120795187(rdh12)
AANG: 118214941(rdh12) 118215328(si:ch211-107o10.3) 118223314 118225694(zgc:112332) 118225695(si:dkey-73n8.3) 118232881 118233951(zgc:153441)
PSPA: 121299084 121307869(si:dkey-73n8.3) 121308219(zgc:112332) 121314247 121330121(rdh12)
RTP: 109913152 109936308(rdh12)
DER: 6542080
DSI: Dsimw501_GD10498(Dsim_GD10498) Dsimw501_GD10500(Dsim_GD10500)
DSR: 110178385
DPE: 6602084
DNV: 115564143
LCQ: 111679271
AARA: 120901288
AME: 552758
BIM: 100745829
MGEN: 117225076
NMEA: 116428599
CGIG: 122402303
ACEP: 105626379
DQU: 106748801
PCF: 106793547
CSOL: 105365360
CBR: CBG04620(Cbr-dhs-22)
TSP: Tsp_04022
GAE: 121371590
EGL: EGR_02372
ATH: AT1G64590
ALY: 9323935
CPAP: 110807030
TCC: 18597799
APRC: 113860614
CAM: 101509179
LJA: Lj1g3v0342000.1(Lj1g3v0342000.1)
FVE: 101295243
RCN: 112193888
MCHA: 111014975
RCU: 8269384
JCU: 105636270
HBR: 110672874
MESC: 110622567
POP: 7487251
PEU: 105122473
PALZ: 118053365
JRE: 109006782
TWL: 119992774
VRI: 117920382
SLY: 101258297
ITR: 116030211
DCR: 108215406
MING: 122087099
BDI: 100827273
TDC: 119297574
SITA: 101786469
PDA: 103710518
EGU: 105056971
DCT: 110107237
PEQ: 110022984
MAJ: MAA_07435
CMT: CCM_01960
MBE: MBM_08426
ANG: ANI_1_1940074(An08g04690)
PTE: PTT_20036
ABP: AGABI1DRAFT59093(AGABI1DRAFT_59093) AGABI1DRAFT70956(AGABI1DRAFT_70956)
ABV: AGABI2DRAFT117623(AGABI2DRAFT_117623) AGABI2DRAFT186625(AGABI2DRAFT_186625) AGABI2DRAFT203820(AGABI2DRAFT_203820)
DFA: DFA_01654
SMIN: v1.2.009977.t1(symbB.v1.2.009977.t1) v1.2.033662.t1(symbB.v1.2.033662.t1)
ALK: ALEK_2395
CCX: COCOR_00754(yciK)
HOH: Hoch_2073
MDI: METDI3947
MEX: Mext_3159
MCH: Mchl_3483
MPO: Mpop_3355
MOR: MOC_4304
META: Y590_15415
MANA: MAMMFC1_03177(fabG_2)
MCOO: MCOO_32000
MMAG: MMAD_31940
MCHE: BB28_17475
MSTE: MSTE_03452
HAU: Haur_3830
ATM: ANT_25440
DGE: Dgeo_1140
DFC: DFI_07860
PBOR: BSF38_01904(rhlG)
GAU: GAU_2064
BVU: BVU_1966
SLI: Slin_0197
HSW: Hsw_2466
FLM: MY04_4115
IAL: IALB_0056
NVN: NVIE_020260(sdr-2)
NEV: NTE_00111
 » show all
Reference
  Authors
Belyaeva OV, Korkina OV, Stetsenko AV, Kim T, Nelson PS, Kedishvili NY
  Title
Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids.
  Journal
Biochemistry 44:7035-47 (2005)
DOI:10.1021/bi050226k
  Sequence
[hsa:145226]
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