KEGG ORTHOLOGY: K11452

ORTHOLOGY: K11452

Entry

K11452                      KO

Symbol

CBX4, PC2

Name

E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]

Pathway

map03083

Polycomb repressive complex

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    K11452  CBX4, PC2; E3 SUMO-protein ligase CBX4
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K11452  CBX4, PC2; E3 SUMO-protein ligase CBX4
   03036 Chromosome and associated proteins
    K11452  CBX4, PC2; E3 SUMO-protein ligase CBX4
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  UBL E3 ligases
   K11452  CBX4, PC2; E3 SUMO-protein ligase CBX4
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Histone modification proteins
   Polycomb repressive complex (PRC) and associated proteins
    Canonical PRC1 (PRC1.2/1.4)
     K11452  CBX4, PC2; E3 SUMO-protein ligase CBX4

Other DBs

GO:

0019789

Genes

HSA:	8535(CBX4)

PTR:	744720(CBX4)

PPS:	100968485(CBX4)

GGO:	101143577(CBX4)

PON:	100456922(CBX4)

NLE:	100581894(CBX4)

HMH:	116483487(CBX4)

MCC:	717683(CBX4)

MCF:	123569543(CBX4)

MTHB:

126939194

MNI:	105469264(CBX4)

CSAB:

103243685(CBX4)

CATY:

105577626(CBX4)

PANU:

101016278(CBX4)

TGE:	112608863(CBX4)

MLEU:

105529826(CBX4)

RRO:	104670513(CBX4)

RBB:	108534269 108534270

TFN:	117066793(CBX4)

PTEH:

111542336(CBX4)

CANG:

105505352(CBX4)

CJC:	100409013(CBX4)

SBQ:	101054399(CBX4)

CIMI:

108301719(CBX4)

CSYR:

103249184(CBX4)

MMUR:

105866740(CBX4)

LCAT:

123620145(CBX4)

PCOQ:

105825311(CBX4)

OGA:	100957819(CBX4)

MMU:	12418(Cbx4)

MCAL:

110305695(Cbx4)

MPAH:

110332199(Cbx4)

RNO:	501403(Cbx4)

MCOC:

116077611(Cbx4)

ANU:	117710816(Cbx4)

MUN:	110550137(Cbx4)

CGE:	100756554(Cbx4)

MAUA:

101823896(Cbx4)

PROB:

127219922(Cbx4)

PLEU:

114708951(Cbx4)

MORG:

121436127(Cbx4)

MFOT:

126500435

AAMP:

119813134(Cbx4)

NGI:	103747301(Cbx4)

HGL:	101715523(Cbx4)

CPOC:

100732734(Cbx4)

CCAN:

109684663(Cbx4)

DORD:

106001177(Cbx4)

DSP:	122099376(Cbx4)

PLOP:

125365612(Cbx4)

NCAR:

124980922

MMMA:

107157840(Cbx4)

OCU:	100359189 127485408

OPI:	101516936(CBX4)

TUP:	102500125(CBX4)

GVR:	103607243(CBX4)

CFA:	608556(CBX4)

CLUD:

112672894(CBX4)

VVP:	112920869(CBX4)

VLG:	121473730(CBX4)

NPO:	129515314(CBX4)

AML:	100479244(CBX4)

UMR:	103665976(CBX4)

UAH:	113244543(CBX4)

UAR:	123803082(CBX4)

ELK:

111160438

LLV:

125087343

MPUF:

101691568(CBX4)

MNP:	132004088(CBX4)

MLK:	131815983(CBX4)

NVS:	122905916(CBX4)

ORO:	101386798(CBX4)

EJU:	114216230(CBX4)

ZCA:	113908070(CBX4)

MLX:	118024403(CBX4)

NSU:	110572490(CBX4)

LWW:	102744211(CBX4)

FCA:	101085023(CBX4)

PYU:	121018016(CBX4)

PBG:	122486179(CBX4)

PVIV:

125151600(CBX4)

LRUF:

124522528

PPAD:

109277139(CBX4)

PUC:

125927627

AJU:

106981882

HHV:	120228273(CBX4)

BTA:	767865(CBX4)

BOM:	102275571(CBX4)

BIU:	109573341(CBX4)

BBUB:

102410857(CBX4)

BBIS:

105000574(CBX4)

CHX:	102185779(CBX4)

OAS:	101110952(CBX4)

BTAX:

128065148(CBX4)

ODA:	120866833(CBX4)

CCAD:

122438049(CBX4)

MBEZ:

129544645(CBX4)

SSC:	100511584(CBX4)

CFR:	102518932(CBX4)

CBAI:

105065584(CBX4)

CDK:	105106247(CBX4)

VPC:	102524641(CBX4)

BACU:

103015607(CBX4)

BMUS:

118887085(CBX4)

LVE:	103079327(CBX4)

OOR:	101288071(CBX4)

DLE:	111182737(CBX4)

PCAD:

102984547(CBX4)

PSIU:

116745923(CBX4)

NASI:

112410469(CBX4)

ECB:	100146225(CBX4)

EPZ:	103544275(CBX4)

EAI:	106845464(CBX4)

MYB:	102249613(CBX4)

MYD:	102774996(CBX4)

MMYO:

118671723(CBX4)

MLF:	102441930(CBX4)

PKL:	118704499(CBX4)

EFUS:

103298372(CBX4)

MNA:	107532022(CBX4)

DRO:	112298698(CBX4)

SHON:

118999484(CBX4)

AJM:	119058607(CBX4)

PDIC:

114504259(CBX4)

PHAS:

123816738(CBX4)

MMF:	118634852(CBX4)

PPAM:

129086476(CBX4)

HAI:	109383613(CBX4)

RFQ:	117013382(CBX4)

PALE:

102894572(CBX4)

PGIG:

120600275(CBX4)

PVP:	105305227(CBX4)

RAY:	107510079(CBX4)

MJV:	108387940(CBX4) 118968120

TOD:	119231926(CBX4)

SARA:

101543710(CBX4)

SETR:

126013240(CBX4)

LAV:	100660028(CBX4)

TMU:

101345103

ETF:	101651289(CBX4)

DNM:	101413107(CBX4)

MDO:	100030846(CBX4)

GAS:	123255903(CBX4)

SHR:	100914730(CBX4)

AFZ:

127560674

PCW:	110218257(CBX4)

OAA:	100079551(CBX4)

GGA:	395354(CBX4)

PCOC:

116232530(CBX4)

MGP:	109370551(CBX4)

CJO:	107322261(CBX4)

TPAI:

128082897(CBX4)

LMUT:

125702298(CBX4)

NMEL:

110407427(CBX4)

APLA:

119713163(CBX4)

ACYG:

125180397(CBX4)

CATA:

118259276(CBX4)

AFUL:

116496637(CBX4)

TGU:	100222038(CBX4)

LSR:	110472430(CBX4)

SCAN:

103819934(CBX4)

PMOA:

120505511(CBX4)

OTC:	121338262(CBX4)

PRUF:

121363431(CBX4)

GFR:	102036674(CBX4)

FAB:	101807463(CBX4)

OMA:	130260576(CBX4)

PHI:	102109503(CBX4)

PMAJ:

107212257(CBX4)

CCAE:

111944342(CBX4)

CCW:	120410961(CBX4)

CBRC:

103613611(CBX4)

ETL:	114060351(CBX4)

ACHL:

103808584(CBX4)

SVG:	106859895(CBX4)

MMEA:

130585626(CBX4)

HRT:	120761073(CBX4)

FPG:	101918311(CBX4)

FCH:	102051414(CBX4)

CLV:	102090732(CBX4)

EGZ:	104130646(CBX4)

NNI:	104014326(CBX4)

TALA:

116960949(CBX4)

PADL:

103917446(CBX4)

AFOR:

103896902(CBX4)

ACHC:

115341796(CBX4)

HLE:	104838767(CBX4)

AGEN:

126043445

GCL:

127024036

LDI:	104348523(CBX4)

MNB:	103772909(CBX4)

SHAB:

115616558(CBX4)

DPUB:

104297966(CBX4)

CPEA:

104398543(CBX4)

CVF:	104288087(CBX4)

RTD:	128917988(CBX4)

CUCA:

104059460(CBX4) 104059461

AAM:	106486011(CBX4)

AROW:

112965967(CBX4)

NPD:	112945325(CBX4)

TGT:	104567669(CBX4)

DNE:	112986746(CBX4)

SCAM:

104149181(CBX4)

ASN:	102381696(CBX4)

AMJ:	109283041(CBX4)

CPOO:

109314893(CBX4)

GGN:	109296219(CBX4)

PSS:	102462257(CBX4)

CMY:	102943617(CBX4)

CCAY:

125621708(CBX4)

DCC:	119842841(CBX4)

CPIC:

101946969(CBX4)

TST:	117887320(CBX4)

CABI:

116834831(CBX4)

MRV:	120383206(CBX4)

ACS:	100562412(cbx4)

ASAO:

132768447(CBX4)

PVT:	110091252(CBX4)

SUND:

121922037(CBX4)

PBI:	103053757(CBX4)

PMUR:

107290958(CBX4)

CTIG:

120308980(CBX4)

TSR:	106542309(CBX4)

PGUT:

117663007(CBX4)

APRI:

131189875(CBX4)

PTEX:

113437039(CBX4)

NSS:	113411964(CBX4)

VKO:	123036919(CBX4)

PMUA:

114589046(CBX4)

PRAF:

128407331(CBX4)

ZVI:	118079707(CBX4)

HCG:	128344715(CBX4)

GJA:	107119856(CBX4)

STOW:

125428316(CBX4)

EMC:	129328539(CBX4)

XLA:	108700981(cbx4.L) 394294(cbx4.S)

XTR:	100124911(cbx4)

NPR:	108792974(CBX4)

RTEM:

120919424(CBX4)

BBUF:

121004673(CBX4)

BGAR:

122940255(CBX4)

MUO:	115473555(CBX4)

GSH:	117367793(CBX4)

DRE:	573110(cbx4)

SRX:	107710010 107710281(cbx4) 107728779 107736694 107758118

SANH:

107669529 107670662 107690020 107701204(cbx4)

SGH:	107553295 107559247 107562304 107591927(cbx4)

CCAR:

109055930 109092326 109102575(cbx4)

CAUA:

113046661 113050689(cbx4) 113052031 113098321

CGIB:

127941428 127953888 127960288 128015482

PTET:

122341652(cbx4) 122347046

LROH:

127163550(cbx4) 127166533

OMC:	131536875(cbx4)

PPRM:

120480512 120489744(cbx4)

RKG:	130081194 130105877(cbx4)

MAMB:

125264159(cbx4) 125272927

CIDE:

127509352 127514860

MASI:

127445751 127449015 127450242 127451116

TROS:

130561035(cbx4)

TDW:	130426548(cbx4)

MANU:

129436534(cbx4)

IPU:	108260285(cbx4) 108273333

IFU:	128599715(cbx4) 128616111

PHYP:

113523693 113528193

SMEO:

124385754 124397318(cbx4)

TFD:	113639652(cbx4) 113656887

TVC:	132845044 132861220(cbx4)

AMEX:

103031044 103045489(cbx4) 111194212

CMAO:

118798576 118802836 118807453 118808600 118821418(cbx4)

EEE:	113573270 113578871

CHAR:

105891371(cbx4) 105892293

TRU:	101075073 101076082

TFS:	130514898(cbx4) 130527320

TNG:	GSTEN00007992G001 GSTEN00033406G001

LCO:	104918816 104921555(cbx4)

NCC:	104943130 104965337(cbx4)

TBEN:

117482707 117492818(cbx4)

CGOB:

115012777 115013642(cbx4)

PGEO:

117443101 117450834(cbx4)

GACU:

117548615(cbx4) 117562541

EMAC:

134864828 134878563(cbx4)

ELY:	117256014 117268102(cbx4)

EFO:	125880141(cbx4) 125886560

PLEP:

121941949 121956972(cbx4)

SLUC:

116039596 116059420(cbx4)

ECRA:

117958387(cbx4) 117960078

ESP:	116702118(cbx4) 116702512

PFLV:

114546081(cbx4) 114569420

GAT:	120825271 120827915(cbx4)

PPUG:

119218382 119220738(cbx4)

AFB:	129095884 129098596(cbx4)

CLUM:

117732082 117735698(cbx4)

PSWI:

130189135(cbx4) 130190401

MSAM:

119888906(cbx4) 119899726

SCHU:

122868712(cbx4) 122872490

CUD:	121507962 121529172(cbx4)

ALAT:

119014537(cbx4) 119025299

MZE:	101467610 101477503

ONL:	100692384 100712470(cbx4)

OAU:	116313067 116331488

OLA:	101158167(cbx4) 101160166

OML:	112146829(cbx4) 112157484

CSAI:

133421943(cbx4) 133453480

XMA:	102230727(cbx4) 102232224

XCO:	114145263(cbx4) 114160311

XHE:	116720474(cbx4) 116735297

PRET:

103463659(cbx4) 103469229

PFOR:

103133063(cbx4) 103141632

PLAI:

106957183 106958633(cbx4)

PMEI:

106904416 106928181(cbx4)

GAF:	122822507(cbx4) 122830155

PPRL:

129363721(cbx4) 129367259

CVG:	107085514(cbx4) 107092841

CTUL:

119790214 119798334

GMU:	124862701 124864374 124869156

NFU:	107376532 107395725

KMR:	108239245(cbx4) 108245485

ALIM:

106524490 106537197

NWH:	119421146(cbx4) 119422699

AOCE:

111577320 111577364

MCEP:

124997939(cbx4)

CSEM:

103384237(cbx4) 103393067

POV:	109627209(cbx4) 109638661

SSEN:

122771351 122785395(cbx4)

HHIP:

117766088(cbx4) 117769489

HSP:	118123342(cbx4) 118125220

SMAU:

118288858(cbx4) 118312967

LCF:	108879647(cbx4) 108884566

SDU:	111218007(cbx4) 111227040

SLAL:

111655477 111667573

XGL:	120784604(cbx4) 120800275

HCQ:	109522747 109527525

SSCV:

125968757 125983501

SBIA:

133506620(cbx4)

PEE:	133404273 133415236(cbx4)

PTAO:

133466062(cbx4) 133476534

BPEC:

110169043 110173862

MALB:

109957911(cbx4) 109969469

BSPL:

114846950 114860475(cbx4)

SJO:	128379113(cbx4) 128381252

SASA:

106564893 106588430 106606687

STRU:

115171669 115178172 115205470 115208615

OTW:	112226250(cbx4) 112230341 112245716

OMY:	110485970 110486808 110486813 110493691

OGO:	123999152(cbx4) 124003354 124015683

ONE:	115103824(cbx4) 115142615

OKI:	109865985 109882827 109894654 116362876

OKE:	118364973 118375040(cbx4) 118389198

SALP:

111953935 111956774 112069120

SNH:	120027300 120032881 120035366 120041278(cbx4)

CCLU:

121551656 121563262 121570359

ELS:	105013028 105021558(cbx4)

SFM:	108937346 108939836(cbx4)

PKI:	111833586(cbx4) 111843199

AANG:

LOC:

PSPA:

ARUT:

PSEX:

120517694(cbx4)

LCM:	102350319(CBX4)

CMK:	103175507(cbx4)

RTP:	109912875(cbx4)

CPLA:

122562177(cbx4)

HOC:	132827788(cbx4)

LERI:

129708292(cbx4)

CRG:

105319128

ATEN:

116300541

» show all

Reference

PMID:21282530

Authors

Vandamme J, Volkel P, Rosnoblet C, Le Faou P, Angrand PO

Title

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

Journal

Mol Cell Proteomics 10:M110.002642 (2011)
DOI:10.1074/mcp.M110.002642

Sequence

[hsa:8535]

LinkDB

DBGET integrated database retrieval system