KEGG ORTHOLOGY: K12047

ORTHOLOGY: K12047

Entry

K12047                      KO

Symbol

MGAM

Name

maltase-glucoamylase [EC:3.2.1.20 3.2.1.3]

Pathway

map00052

Galactose metabolism

map00500

Starch and sucrose metabolism

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map04973

Carbohydrate digestion and absorption

Reaction

R00028

maltose glucohydrolase

R00801

sucrose glucohydrolase

R00802

sucrose alpha-glucohydrolase

R01790

1,4-alpha-D-glucan glucohydrolase

R01791

dextrin 6-alpha-D-glucanohydrolase

R06087

R06088

R06199

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    K12047  MGAM; maltase-glucoamylase
   00500 Starch and sucrose metabolism
    K12047  MGAM; maltase-glucoamylase
09150 Organismal Systems
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K12047  MGAM; maltase-glucoamylase
Enzymes [BR:ko01000]
3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.3  glucan 1,4-alpha-glucosidase
     K12047  MGAM; maltase-glucoamylase
    3.2.1.20  alpha-glucosidase
     K12047  MGAM; maltase-glucoamylase

Other DBs

GO:	0004558 0004339

CAZy:

GH31

Genes

HSA:	8972(MGAM) 93432(MGAM2)

PTR:	463789(MGAM) 463790(MGAM2)

PPS:	100969608(MGAM2) 100996199(MGAM)

GGO:	101127404 101131000(MGAM2)

PON:	100450850(MGAM) 100455657(MGAM2) 112131530

NLE:	100590310(MGAM) 100605801(MGAM2)

HMH:

116814442

MCC:	695030(MGAM) 695370(MGAM2)

MCF:	102120094(MGAM) 102122119(MGAM2)

MTHB:

126949627

MNI:	105471250(MGAM2) 105471255(MGAM)

CSAB:

103227042(MGAM) 103227409

CATY:

105589693(MGAM) 105589694(MGAM2)

PANU:

101001849(MGAM) 101002905(MGAM2)

TGE:	112620977(MGAM2) 112621698(MGAM)

MLEU:

105533558 105533559(MGAM2) 105550543(MGAM)

RRO:	104655094(MGAM2) 104659721(MGAM)

RBB:	108541550(MGAM) 108541557(MGAM2)

TFN:	117072657(MGAM2) 117073450(MGAM)

PTEH:

111521513(MGAM) 111521521(MGAM2)

CANG:

105511204(MGAM) 105511205(MGAM2)

CJC:	100397043(MGAM2) 100397416(MGAM)

SBQ:	101054069(MGAM) 101054392

CIMI:

108283438(MGAM) 108291166

CSYR:

103261012(MGAM) 103261024(MGAM2)

MMUR:

105873257(MGAM) 105873269(MGAM2)

LCAT:

123646922(MGAM) 123646923(MGAM2)

PCOQ:

105814716(MGAM)

OGA:	100967202(MGAM)

MMU:	232714(Mgam)

MCAL:

110296574(Mgam) 110296575(Mgam2)

MPAH:

110315970 110316775 110316776

RNO:	103690059(Mgam) 312272(Mgam2)

MCOC:

116098507(Mgam) 116098783(Mgam2)

ANU:	117720542(Mgam) 117721005(Mgam2)

MUN:	110553941(Mgam)

CGE:	100769016(Mgam) 118239532(Mgam2)

MAUA:

101844249(Mgam2) 101844514(Mgam)

PROB:

127214238 127214309

PLEU:

114684450 114684453

MORG:

121435540(Mgam) 121435541(Mgam2)

MFOT:

126505288

AAMP:

119806650(Mgam) 119806651(Mgam2)

NGI:	103724791(Mgam2) 103726140(Mgam)

HGL:	101711183(Mgam) 101711548(Mgam2)

CPOC:

100714141

CCAN:

109695405 109695424 109695435(Mgam2)

DORD:

105989478(Mgam2) 105989583(Mgam)

DSP:	122105789(Mgam2)

PLOP:

125345309 125345666 125345669

NCAR:

124991254

MMMA:

107148995(Mgam2) 107149112(Mgam)

OCU:

100359253

OPI:	101531923 101532167

TUP:	102479933(MGAM) 102480355

GVR:	103598901(MGAM) 103598903

CFA:	475523(MGAM) 482756(MGAM2)

CLUD:

112650976(MGAM2) 112650979(MGAM)

VVP:	112907034(MGAM) 112907048(MGAM2)

VLG:	121489170 121489171(MGAM)

NPO:	129515796 129515797(MGAM)

AML:	100466340(MGAM2) 100466584(MGAM)

UMR:	103669012(MGAM) 103669102

UAH:

113265231

ELK:	111151996 111152008

LLV:	125080533 125080675

MPUF:

101672847(MGAM2) 101673126(MGAM)

MNP:	132015509(MGAM2) 132015628(MGAM)

MLK:	131829864 131829865(MGAM)

NVS:	122905146 122905147(MGAM)

ORO:	101380291(MGAM) 101381158(MGAM2)

EJU:

114211793

ZCA:	113911844(MGAM2) 113912001(MGAM)

MLX:	118020576(MGAM2) 118021172(MGAM)

NSU:	110582814 110582816(MGAM)

LWW:	102732629(MGAM)

FCA:	101094582(MGAM) 101094837

PYU:	121028218(MGAM2) 121028219(MGAM)

PCOO:

112866452(MGAM) 112866453(MGAM2)

PBG:	122488345 122488420(MGAM)

PVIV:

125151689(MGAM) 125154018

LRUF:

124523313 124523314

PTG:	102963503(MGAM) 102963785(MGAM2)

PPAD:

109269136(MGAM2) 109269137(MGAM)

PUC:	125930217 125930219

AJU:	106970401 106970446

HHV:	120232971 120232979(MGAM)

BTA:	100296901 100336421(MGAM)

BOM:	102265977(MGAM) 102270662(MGAM2)

BIU:	109557962(MGAM2)

BBUB:

102404728(MGAM) 102411245

BBIS:

104999396(MGAM) 104999462

CHX:	102179067(MGAM) 102180726(MGAM2)

OAS:	101113407(MGAM) 101113672

BTAX:

128046312

ODA:	120877553(MGAM) 120877676

CCAD:

122438735(MGAM)

MBEZ:

129551981(MGAM)

SSC:	100623494(MGAM2) 102160115(MGAM)

CFR:	102514558(MGAM) 102514818

CBAI:

105063006(MGAM) 105063187

CDK:	105097330(MGAM2) 105097331(MGAM)

VPC:	102541896(MGAM) 102542147(MGAM2)

BACU:

103004683(MGAM)

BMUS:

118900603 118901203

LVE:	103081817(MGAM)

OOR:	101288403(MGAM)

DLE:	111177505(MGAM)

PCAD:

102982741(MGAM)

PSIU:

116759211(MGAM)

NASI:

112408430(MGAM)

ECB:	100064486(MGAM) 100065270(MGAM2)

EPZ:	103558278 103558279(MGAM)

EAI:	106842570(MGAM2) 106842605(MGAM)

MYB:	102255004(MGAM) 102262411(MGAM2)

MYD:	102758728(MGAM2) 102768888(MGAM)

MMYO:

118666328(MGAM) 118666609(MGAM2)

MLF:	102425458(MGAM) 102436473

PKL:	118714059(MGAM)

EFUS:

103294143(MGAM2) 103294144

MNA:	107531078(MGAM2) 107531085(MGAM)

DRO:	112299863(MGAM2) 112299904(MGAM)

SHON:

118989068(MGAM) 118989194(MGAM2)

AJM:

119044546

PDIC:

114507354(MGAM) 118497205(MGAM2)

PHAS:

123829674(MGAM) 123829675(MGAM2)

MMF:	118619711(MGAM2) 118619753(MGAM)

PPAM:

129063250(MGAM2) 129063475(MGAM)

HAI:	109395594(MGAM2) 109395610(MGAM)

RFQ:	117017993(MGAM2) 117018014(MGAM)

PALE:

102878555 102897997

PGIG:

120600991(MGAM) 120600992(MGAM2)

PVP:	105291597 105291649(MGAM2)

RAY:	107514213 107516912(MGAM) 107516970

MJV:	108399286 108399287

TOD:	119247910(MGAM) 119250913

SARA:

101544608(MGAM2) 101544875(MGAM)

SETR:

126023032(MGAM)

LAV:	100661007(MGAM2) 100661293(MGAM)

TMU:	101350583 101350828

ETF:	101652342(MGAM2) 101652663

DNM:	101415412(MGAM) 101415845(MGAM2)

MDO:	100009833(MGAM) 100009866

GAS:

123249910

SHR:	100935157(MGAM) 105750789

AFZ:

127563943

PCW:	110216165 110216253(MGAM)

OAA:	100093611 107546901

GGA:	425007(SI) 425545(MGAM)

PCOC:

116235502(SI)

MGP:	100542024(SI)

CJO:	107307407 107318345(SI)

TPAI:

128081932(SI)

LMUT:

125687598 125697796(SI)

NMEL:

110398907(SI)

APLA:

101798588(SI) 119715237

ACYG:

106032152(SI) 106049821

CATA:

118253122 118261414 126913404(SI)

AFUL:

116492651(SI)

TGU:	100189934(SI)

LSR:	110480372(SI)

SCAN:

103815590(SI)

PMOA:

120504229(SI)

OTC:	121336533(SI)

PRUF:

121353833(SI)

GFR:	102044952(SI)

FAB:	101807450(SI)

OMA:	130256715(SI)

PHI:	102105067(SI) 102113603

PMAJ:

107198914 107208530(SI)

CCAE:

111933809 111933810 111943230

CCW:	104688154(SI)

CBRC:

103615710(SI)

ETL:	114063685(SI)

ZAB:

102063267

SVG:	106858087(SI)

MMEA:

130584424

HRT:	120757316(SI)

FPG:	101919765(SI)

FCH:	102046830(SI)

CLV:

102096277

EGZ:	104125241 104129726

NNI:

104009172

ACUN:

113483417(SI)

TALA:

104357119 104365825(SI)

PADL:

103924874 103925289(SI)

AFOR:

103903799

ACHC:

115347679(SI) 115350190

HLE:	104833476 104834233

AGEN:

126039338 126052726

GCL:	127019938 127028050

CCRI:

104160440

OHA:	104334444(SI) 104338083

SHAB:

DPUB:

CPEA:

AVIT:

CVF:	104285968(SI) 104289447

RTD:	128911229(SI)

CUCA:

104056868(SI) 104059944

BRHI:

104500091

AAM:	106494316 106499607(SI)

AROW:

112963856(SI) 112967101

NPD:	112944324 112952404(SI)

TGT:

104564677

DNE:	112986300 112986431(SI)

SCAM:

104140053(SI) 104140063

ASN:	102369367 102369627

AMJ:	102559297(MGAM)

CPOO:

109308399(SI)

GGN:	109287947(SI)

PSS:	102452896(SI)

CMY:	102948110(SI)

CCAY:

125642869(SI)

DCC:	119861763(SI)

CPIC:

101936465(SI)

TST:	117882729(SI)

CABI:

116821366 116821459

MRV:	120371851(SI)

ACS:	100563205(si)

ASAO:

132770538(SI)

PVT:	110085330(MGAM)

SUND:

121927072(SI)

PBI:

PMUR:

CTIG:

TSR:

PGUT:

117678221(SI)

APRI:

131201324(SI)

PTEX:

113439709(SI)

VKO:	123025578(SI)

PMUA:

114597944(SI)

PRAF:

128414728(SI)

ZVI:	118093410(SI)

HCG:	128350622(SI)

GJA:	107110072(SI)

STOW:

125438617(SI)

EMC:	129332037(SI)

XLA:

108717032

XTR:	100379714(mgam)

NPR:	108797771(MGAM)

RTEM:

120936722(SI)

BBUF:

120997858(SI)

BGAR:

122934404(SI)

MUO:	115478812(SI)

GSH:	117366338(SI)

DRE:	100148922(si)

SRX:	107735994 107755676

SANH:

107660689 107687769

SGH:	107572113 107600770

CCAR:

109053216

CAUA:

113068422 113118133

CGIB:

127934210 127935784 127977688

PTET:

122323148 122335490

LROH:

127162031 127180337(si)

OMC:	131524618(si) 131525614

PPRM:

120473722(si) 120475411

RKG:	130100469(si)

MAMB:

125253860(si) 125274221

CIDE:

127499478 127509845

MASI:

127416901 127456245

TROS:

130562577(si)

TDW:	130435439(si)

MANU:

129419164(si)

IPU:	108264758(si)

IFU:	128606897(si)

PHYP:

113526936

SMEO:

124395712(si)

TFD:	113659427(si)

TVC:	132851029(si)

CMAO:

118817958(si)

EEE:

113576976

CHAR:

105894942 105897125(si)

TRU:

101063256

TFS:	130535462(si)

TNG:	GSTEN00027778G001

LCO:	104936088(si)

TBEN:

117470040(si)

CGOB:

115017553(si)

PGEO:

117457891(si)

GACU:

117558061(si)

EMAC:

134880681(si)

ELY:	117259220(si)

EFO:	125888684(si)

PLEP:

121943416(si)

SLUC:

116045592(si)

ECRA:

117942215(si)

ESP:	116684518(si)

PFLV:

114552195

GAT:	120825523(si)

PPUG:

119212926(si)

AFB:	129109626(si)

CLUM:

117741804(si)

PSWI:

130211277(si)

MSAM:

119883214(si)

SCHU:

122879164(si)

CUD:	121521134(si)

ALAT:

119030828(si)

MZE:

101468872

ONL:	100694894 100698032

OAU:	116330348 116331833

OLA:	101164831(si)

OML:	112149880(si)

CSAI:

133441634(si)

XMA:	102216935(si)

XCO:	114133555(si)

XHE:

116708258

PRET:

103474416(si)

PFOR:

103153791

PLAI:

106960639

PMEI:

106917366

GAF:	122833003(si)

PPRL:

129358787(si)

CVG:	107086952(si)

CTUL:

119775253(si)

GMU:	124884762(si)

NFU:	107374472 107380514

KMR:	108240478 108240540

ALIM:

106517352 106520634(si)

NWH:	119408483 119411546

AOCE:

111579782

MCEP:

125013595(si)

CSEM:

103377566(si)

POV:

109634420

SSEN:

122773422(si)

HHIP:

117772938(si)

HSP:	118106157(si)

SMAU:

118299649(si)

LCF:

108886343

SDU:

111238462

SLAL:

111652647

XGL:	120792081(si)

HCQ:

109525537

SSCV:

125972083

SBIA:

133505134(si)

PEE:	133404887(si)

PTAO:

133482310(si)

BPEC:

110174480

MALB:

109960375(si)

BSPL:

114867550 114868619

SJO:	128360105(si)

SASA:

106613210

STRU:

115206619

OTW:	112236299(si)

OMY:	110518712(si)

OGO:	124004852(si)

OKE:	118379579(si)

SNH:	120028507(si)

CCLU:

121567588

ELS:

105028748

SFM:	108924670(si)

PKI:

111833940

AANG:

118210249(si)

LOC:	102683264(si)

PSPA:

121326603(si)

ARUT:

117416728(si)

PSEX:

120531461(si)

LCM:	102351524(SI)

CMK:	103175535(si)

RTP:	109918926(si)

CPLA:

122556370(si)

HOC:	132821339(si)

LERI:

129703681(si)

PMRN:

116954442

LRJ:

133357558

BFO:	118419827 118419828

BBEL:

109477466

CIN:

100175461

SCLV:

120327875 120328284

SPU:	584897 592667

LPIC:

APLC:

AJC:

SKO:

LBD:

FCD:

DPZ:

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

ESN:

HAZT:

CSCU:

PTEP:

ABRU:

129957601 129957645 129971512

UDV:	129216387 129217505

SDM:

LPOL:

PMEO:

TSP:

PVUL:

PCAN:

BGT:

GAE:

HRF:	124112457 124147610

HRJ:

124254995

CRG:	105328796 105333497

CVN:	111099715 111099716 111119014 111119178

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

LAK:	106172255 106172919 106181238

EPA:

AMIL:

PDAM:

SPIS:

DGT:	114517589 114525400

XEN:

124452282

HMG:

100205877

TAD:	TRIADDRAFT_37758

» show all

Reference

PMID:18036614

Authors

Sim L, Quezada-Calvillo R, Sterchi EE, Nichols BL, Rose DR

Title

Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity.

Journal

J Mol Biol 375:782-92 (2008)
DOI:10.1016/j.jmb.2007.10.069

Sequence

[hsa:8972]

LinkDB

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