KEGG ORTHOLOGY: K12047

ORTHOLOGY: K12047

Entry

K12047                      KO

Symbol

MGAM

Name

maltase-glucoamylase [EC:3.2.1.20 3.2.1.3]

Pathway

map00052

Galactose metabolism

map00500

Starch and sucrose metabolism

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map04973

Carbohydrate digestion and absorption

Reaction

R00028

maltose glucohydrolase

R00801

sucrose glucohydrolase

R00802

sucrose alpha-glucohydrolase

R01790

1,4-alpha-D-glucan glucohydrolase

R01791

dextrin 6-alpha-D-glucanohydrolase

R06087

R06088

R06199

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00052 Galactose metabolism
    K12047  MGAM; maltase-glucoamylase
   00500 Starch and sucrose metabolism
    K12047  MGAM; maltase-glucoamylase
09150 Organismal Systems
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    K12047  MGAM; maltase-glucoamylase
Enzymes [BR:ko01000]
3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.3  glucan 1,4-alpha-glucosidase
     K12047  MGAM; maltase-glucoamylase
    3.2.1.20  alpha-glucosidase
     K12047  MGAM; maltase-glucoamylase

Other DBs

GO:	0004558 0004339

CAZy:

GH31

Genes

HSA:	8972(MGAM) 93432(MGAM2)

PTR:	463789(MGAM) 463790(MGAM2)

PPS:	100969608(MGAM2) 100996199(MGAM)

GGO:	134756356(MGAM2)

PON:	100455657(MGAM2)

PPYG:

129040056(MGAM2)

NLE:	100590310(MGAM) 100605801(MGAM2)

HMH:

116814442

SSYN:

129484048(MGAM2) 129485099(MGAM)

MCC:	695030(MGAM) 695370(MGAM2)

MCF:	102120094(MGAM)

MTHB:

126949627

MNI:	105471250(MGAM2) 105471255(MGAM)

CSAB:

103227042(MGAM) 103227409

CATY:

105589693(MGAM) 105589694(MGAM2)

PANU:

101001849(MGAM) 101002905(MGAM2)

TGE:	112620977(MGAM2) 112621698(MGAM)

MLEU:

105533558 105533559(MGAM2) 105550543(MGAM)

RRO:	104655094(MGAM2) 104659721(MGAM)

RBB:	108541550(MGAM) 108541557(MGAM2)

TFN:	117072657(MGAM2) 117073450(MGAM)

PTEH:

111521513(MGAM) 111521521(MGAM2)

CANG:

105511204(MGAM) 105511205(MGAM2)

CJC:	100397043(MGAM2) 100397416(MGAM)

SBQ:	101054069(MGAM) 101054392

CIMI:

108283438(MGAM) 108291166

ANAN:

105713652(MGAM) 105713653(MGAM2)

CSYR:

103261012(MGAM) 103261024(MGAM2)

MMUR:

105873257(MGAM) 105873269(MGAM2)

LCAT:

123646922(MGAM) 123646923(MGAM2)

PCOQ:

105814716(MGAM)

OGA:	100967202(MGAM)

MMU:	232714(Mgam) 638904(Mgam2-ps)

MCAL:

110296574(Mgam) 110296575(Mgam2)

MPAH:

110315970 110316775 110316776

RNO:	103690059(Mgam) 312272(Mgam2)

MCOC:

116098507(Mgam) 116098783(Mgam2)

ANU:	117720542(Mgam) 117721005(Mgam2)

ASYL:

127677883(Mgam2) 127678518(Mgam)

MUN:	110553941(Mgam) 110553966

CGE:	100769016(Mgam) 118239532(Mgam2)

MAUA:

101844249(Mgam2) 101844514(Mgam)

PROB:

127214238 127214309

PLEU:

114684450 114684453

MORG:

121435540(Mgam) 121435541(Mgam2)

MFOT:

126505288

AAMP:

119806650(Mgam) 119806651(Mgam2)

NGI:	103724791(Mgam2) 103726140(Mgam)

HGL:	101711183(Mgam) 101711548(Mgam2)

CPOC:

100714141

CCAN:

109695405 109695424 109695435(Mgam2)

DORD:

105989478(Mgam2) 105989583(Mgam)

DSP:	122105789(Mgam2)

DMER:

138810213(Mgam2)

PLOP:

125345309 125345666 125345669

NCAR:

124991254

MMMA:

107148995(Mgam2) 107149112(Mgam)

ITI:	101957070(Mgam) 101967167(Mgam2)

OCU:

100359253

OPI:	101531923 101532167

TUP:	102479933(MGAM) 102480355

GVR:	103598901(MGAM) 103598903

CFA:	475523(MGAM) 482756(MGAM2)

CLUD:

112650976(MGAM2) 112650979(MGAM)

VVP:	112907034(MGAM) 112907048(MGAM2)

VLG:	121489170 121489171(MGAM)

NPO:	129515796 129515797(MGAM)

AML:	100466340(MGAM2) 100466584(MGAM)

UMR:	103669012(MGAM) 103669102

UAH:	113265231(MGAM)

ELK:	111151996 111152008

LLV:	125080533 125080675

MPUF:

101672847(MGAM2) 101673126(MGAM)

MNP:	132015509(MGAM2) 132015628(MGAM)

MLK:	131829864 131829865(MGAM)

NVS:	122905146 122905147(MGAM)

ORO:	101380291(MGAM) 101381158(MGAM2)

EJU:

114211793

ZCA:	113911844(MGAM2) 113912001(MGAM)

MLX:	118020576(MGAM2) 118021172(MGAM)

NSU:	110582814 110582816(MGAM)

LWW:	102732629(MGAM)

FCA:	101094582(MGAM) 101094837

PYU:	121028218(MGAM2) 121028219(MGAM)

PCOO:

112866452(MGAM) 112866453(MGAM2)

PBG:	122488345 122488420(MGAM)

PVIV:

125151689(MGAM) 125154018

LRUF:

124523313 124523314

LGF:	123606991 123606992(MGAM)

AJU:	106970401 106970446

PTG:	102963503(MGAM) 102963785(MGAM2)

PPAD:

109269136(MGAM2) 109269137(MGAM)

PUC:	125930217 125930219

PLEZ:

122212904(MGAM) 122212905

HHV:	120232971 120232979(MGAM)

BTA:	100296901 100336421(MGAM)

BOM:	102265977(MGAM) 102270662(MGAM2)

BIU:	109557962(MGAM2)

BBUB:

102404728(MGAM) 102411245

BBIS:

104999396(MGAM) 104999462

CHX:	102179067(MGAM) 102180726(MGAM2)

OAS:	101113407(MGAM) 101113672

BTAX:

128046312

CSUM:

138079742 138080104(MGAM)

ODA:	120877553(MGAM) 120877676

CCAD:

122438735(MGAM)

MREE:

136170351(MGAM) 136170352

OVR:	110140368(MGAM2) 110148808(MGAM)

MBEZ:

129551981(MGAM)

SSC:	100623494(MGAM2) 102160115(MGAM)

CFR:	102514558(MGAM) 102514818

CBAI:

105063006(MGAM) 105063187

CDK:	105097330(MGAM2) 105097331(MGAM)

VPC:	102541896(MGAM) 102542147(MGAM2)

BACU:

103004683(MGAM)

BMUS:

118900603 118901203

LVE:	103081817(MGAM)

OOR:	101288403(MGAM)

LALB:

132524507

GMF:

115851771

DLE:	111177505(MGAM)

PCAD:

102982741(MGAM)

PSIU:

116759211(MGAM)

PPHC:

136127961

NASI:

112408430(MGAM)

ECB:	100064486(MGAM) 100065270(MGAM2)

EPZ:

103558279

EAI:	106842570(MGAM2) 106842605(MGAM)

MYB:	102255004(MGAM) 102262411(MGAM2)

MYD:	102758728(MGAM2) 102768888(MGAM)

MMYO:

118666328(MGAM) 118666609(MGAM2)

MLF:	102425458(MGAM) 102436473

MDT:	132211347 132242847(MGAM)

MYUM:

139015973 139016268(MGAM)

PKL:	118714059(MGAM)

EFUS:

103294143(MGAM2) 103294144

MNA:	107531078(MGAM2) 107531085(MGAM)

DRO:	112299863(MGAM2) 112299904(MGAM)

SHON:

118989068(MGAM) 118989194(MGAM2)

AJM:	119044546(MGAM)

PDIC:

114507354(MGAM) 118497205(MGAM2)

PHAS:

123829674(MGAM) 123829675(MGAM2)

MMF:	118619711(MGAM2) 118619753(MGAM)

PPAM:

129063250(MGAM2) 129063475(MGAM)

HAI:	109395594(MGAM2) 109395610(MGAM)

RFQ:	117017993(MGAM2) 117018014(MGAM)

PALE:

102878555 102897997

PGIG:

120600991(MGAM) 120600992(MGAM2)

PVP:	105291597 105291649(MGAM2)

RAY:	107514213 107516912 107516970

MJV:	108399286 108399287

TOD:	119247910(MGAM) 119250913

SARA:

101544608(MGAM2) 101544875(MGAM)

SFUM:

130032398 130032401 130032405(MGAM)

SETR:

126023032(MGAM)

LAV:	100661007(MGAM2) 100661293(MGAM)

TMU:	101350583 101350828

ETF:	101652342(MGAM2) 101652663

DNM:	101415412(MGAM) 101415845(MGAM2)

MDO:	100009833(MGAM) 100009866

GAS:

123249910

SHR:	100935157(MGAM) 105750789

AFZ:

127563943

PCW:	110216165 110216253(MGAM)

PBRV:

138160684(MGAM)

OAA:	100093611 107546901

GGA:	425007(SI) 425545(MGAM)

PCOC:

116235502(SI)

MGP:	100542024(SI)

CJO:	107307407 107318345(SI)

TPAI:

128081932(SI)

LMUT:

125687598 125697796(SI)

NMEL:

110398907(SI)

APLA:

101798588(SI) 119715237

ACYG:

106032152(SI) 106049821

CATA:

118253122 118261414 126913404(SI)

AFUL:

116492651(SI)

TGU:	100189934(SI)

LSR:	110480372(SI)

SCAN:

103815590(SI)

PMOA:

120504229(SI)

OTC:	121336533(SI)

PRUF:

121353833(SI)

ATRC:

139595142(SI)

GFR:	102044952(SI)

FAB:	101807450(SI)

OMA:	130256715(SI)

PHI:	102105067(SI) 102113603

PMAJ:

107198914 107208530(SI)

CCAE:

111933809 111933810 111943230

CCW:	104688154(SI)

CBRC:

103615710(SI)

ACOE:

138114429(SI)

ETL:	114063685(SI)

ZAB:

102063267

ZLE:	135451478(SI)

SVG:	106858087(SI)

MMEA:

130584424

HRT:	120757316(SI)

SATI:

136365725(SI)

CCIC:

134047993(SI)

FPG:	101919765(SI)

FCH:	102046830(SI)

CCRI:

104160440

SHAB:

115612026

ACUN:

113483417(SI)

TALA:

104357119 104365825(SI)

ACHC:

115347679(SI) 115350190

HLE:	104833476 104834233

AGEN:

126039338 126052726

HHAR:

128149523(SI) 128150332

GCL:	127019938 127028050

DPUB:

104308890 104308979

AVIT:

104278218

BRHI:

104500091

EGZ:	104125241 104129726

NNI:

104009172

PADL:

103924874 103925289(SI)

AFOR:

103903799

CBOY:

140645300 140654032(SI)

CLV:

102096277

CNIC:

135991327 135999803

CUCA:

104056868(SI) 104059944

OHA:	104334444(SI) 104338083

CPEA:

104386435 104389475

CVF:	104285968(SI) 104289447

RTD:	128911229(SI)

CRID:

134509454 134517087(SI)

AAM:	106494316 106499607(SI)

AROW:

112963856(SI) 112967101

NPD:	112944324 112952404(SI)

TGT:

104564677

DNE:	112986300 112986431(SI)

SCAM:

104140053(SI) 104140063

ASN:	102369367 102369627

AMJ:	102559297(MGAM)

CPOO:

109308399(SI)

GGN:	109287947(SI)

PSS:	102452896(SI)

CMY:	102948110(SI)

CCAY:

125642869(SI)

DCC:	119861763(SI)

CPIC:

101936465(SI)

TST:	117882729(SI)

CABI:

116821366 116821459

MRV:	120371851(SI)

ACS:	100563205(si)

ASAO:

132770538(SI)

PVT:	110085330(MGAM)

SUND:

121927072(SI)

PBI:

PMUR:

CTIG:

TSR:

PGUT:

117678221(SI)

PCAE:

139318840(SI)

APRI:

131201324(SI)

PTEX:

113439709(SI)

VKO:	123025578(SI)

PMUA:

114597944(SI)

PRAF:

128414728(SI)

ZVI:	118093410(SI)

HCG:	128350622(SI)

GJA:	107110072(SI)

STOW:

125438617(SI)

EMC:	129332037(SI)

XLA:

108717032

XTR:	100379714(mgam)

NPR:	108797771(MGAM)

RTEM:

120936722(SI)

ACAT:

141139731(SI)

BBUF:

120997858(SI)

BGAR:

122934404(SI)

DTC:	141092612(SI)

PWL:	138265481(SI)

MUO:	115478812(SI)

GSH:	117366338(SI)

DRE:	100148922(si)

SRX:	107735994 107755676

SANH:

107660689 107687769

SGH:	107572113 107600770

CCAR:

109053216 109063204 109102866

CAUA:

113068422 113118133

CGIB:

127934210 127935784 127977688

PTET:

122323148 122335490

LROH:

127162031 127180337(si)

GRF:	141331347 141345367

OMC:	131524618(si) 131525614

PPRM:

120473722(si) 120475411

RKG:	130100469(si)

MAMB:

125253860(si) 125274221

CIDE:

127499478 127509845

CERY:

137017041 137023191(si)

MASI:

127416901 127456245

TROS:

130562577(si)

TDW:	130435439(si)

MANU:

129419164(si)

PDAB:

135739801(si)

IPU:	108264758(si)

IFU:	128606897(si)

PHYP:

113526936

SMEO:

124395712(si)

TFD:	113659427(si)

TVC:	132851029(si)

CGAR:

128527673(si)

NGRA:

132888086(si)

TRN:	134322994(si)

AMEX:

125804532(si)

CMAO:

118817958(si)

EEE:

113576976

CHAR:

105894942 105897125(si)

SPIL:

134100057(si)

TRU:

101063256

TFS:	130535462(si)

TNG:	GSTEN00027778G001

LCO:	104936088(si)

TBEN:

117470040(si)

CGOB:

115017553(si)

PGEO:

117457891(si)

GACU:

117558061(si)

EMAC:

134880681(si)

ELY:	117259220(si)

EFO:	125888684(si)

PLEP:

121943416(si)

SLUC:

116045592(si)

ECRA:

117942215(si)

ESP:	116684518(si)

PFLV:

114552195

GAT:	120825523(si)

PPUG:

119212926(si)

AFB:	129109626(si)

CLUM:

117741804(si)

PSWI:

130211277(si)

CANA:

137790437(si)

CVE:	137871116(si)

MSAM:

119883214(si)

SCHU:

122879164(si)

CUD:	121521134(si)

SPUL:

138596833(si)

LMIX:

132980247(si)

ALAT:

119030828(si)

ASTR:

137596558(si)

MZE:

101468872

ONL:	100694894 100698032

OAU:	116330348 116331833

OLA:	101164831(si)

OML:	112149880(si)

CSAI:

133441634(si)

XMA:	102216935(si)

XCO:	114133555(si)

XHE:

116708258

PRET:

103474416(si)

PFOR:

103153791

PLAI:

106960639

PMEI:

106917366

GAF:	122833003(si)

PPRL:

129358787(si)

CVG:	107086952(si)

CTUL:

119775253(si)

GMU:	124884762(si)

NFU:	107374472 107380514

KMR:	108240478 108240540

ALIM:

106517352 106520634(si)

NWH:	119408483 119411546

AOCE:

111579782(si)

EJA:	138197218(si)

BFRE:

138614220(si)

MCEP:

125013595(si)

CSEM:

103377566(si)

POV:

109634420

SSEN:

122773422(si)

SSOE:

131462638(si)

HHIP:

117772938(si)

HSP:	118106157(si)

PPLT:

128440142(si)

SMAU:

118299649(si)

LCF:

108886343

SDU:

111238462

SLAL:

111652647

XGL:	120792081(si)

HCQ:

109525537

SSCV:

125972083(si)

SBIA:

133505134(si)

PEE:	133404887(si)

PTAO:

133482310(si)

BPEC:

110174480

ENY:	140372515(si)

MALB:

109960375(si)

BSPL:

114867550 114868619

SJO:	128360105(si)

SSCO:

133980167(si)

GMH:	115561276(si)

SASA:

106613210

STRU:

115206619

OTW:	112236299(si)

OMY:	110518712(si)

OGO:	124004852(si)

OKE:	118379579(si)

OMM:	135546677(si)

OCLA:

139382256

SNH:	120028507(si)

CCLU:

121567588

ELS:

105028748

OEP:	134029265(si)

SFM:	108924670(si)

PKI:

111833940

AANG:

118210249(si)

AROT:

135236084(si)

CCOG:

133107706(si)

LOC:	102683264(si)

PSPA:

121326603(si)

ARUT:

117416728(si)

PSEX:

120531461(si)

LCM:	102351524(SI)

CMK:	103175535(si)

RTP:	109918926(si)

CPLA:

122556370(si)

HOC:	132821339(si)

LERI:

129703681(si)

HAKA:

140725492(si)

PMRN:

116954442

LRJ:

133357558

BFO:	118419827 118419828

BBEL:

109477466

CIN:

100175461

SCLV:

120327875 120328284

SPU:	584897 592667

LPIC:

AJJ:

APLC:

AFIL:

AJC:

SKO:

PFLL:

LBD:

FCD:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

ESN:

PORN:

HAZT:

CSCU:

PTEP:

ABRU:

129957601 129957645 129971512

UDV:	129216387 129217505

SDM:

LPOL:

PMEO:

TSP:

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:	124112457 124147610

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111099715 111099716 111119014 111119178

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

LJP:	135471856 135471857

LAK:	106172255 106172919 106181238

EPA:

110239595

PDAM:

113670736

SPIS:

111324689

DGT:	114517589 114525400

XEN:

124452282

HMG:

100205877

TAD:	TRIADDRAFT_37758

» show all

Reference

PMID:18036614

Authors

Sim L, Quezada-Calvillo R, Sterchi EE, Nichols BL, Rose DR

Title

Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity.

Journal

J Mol Biol 375:782-92 (2008)
DOI:10.1016/j.jmb.2007.10.069

Sequence

[hsa:8972]

LinkDB

DBGET integrated database retrieval system