Homo sapiens (human): 8972 Help Entry 8972              CDS       T01001                                  Symbol MGAM, MG, MGA Name (RefSeq) maltase-glucoamylase   KO K12047   maltase-glucoamylase [EC:3.2.1.20 3.2.1.3] Organism hsa  Homo sapiens (human) Pathway hsa00052   Galactose metabolism hsa00500   Starch and sucrose metabolism hsa01100   Metabolic pathways hsa04973   Carbohydrate digestion and absorption Network nt06017  Glycogen metabolism   Element N00720   Glycogen degradation (amylase) Drug target Acarbose:  D00216<JP/US> Emiglitate:  D09779 Miglitol:  D00625<JP/US> Voglibose:  D01665<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09101 Carbohydrate metabolism    00052 Galactose metabolism     8972 (MGAM)    00500 Starch and sucrose metabolism     8972 (MGAM)  09150 Organismal Systems   09154 Digestive system    04973 Carbohydrate digestion and absorption     8972 (MGAM) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.3  glucan 1,4-alpha-glucosidase      8972 (MGAM)     3.2.1.20  alpha-glucosidase      8972 (MGAM) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glyco_hydro_31_2nd Glyco_hydro_31_3rd Trefoil Gal_mutarotas_2 New_glue Motif Other DBs NCBI-GeneID:  8972 NCBI-ProteinID:  NP_004659 OMIM:  154360 HGNC:  7043 Ensembl:  ENSG00000257335 UniProt:  O43451 Structure PDB LinkDB All DBs Position 7:141986518..142106747 Genome browser AA seq 1857 aa AA seqDB search MARKKLKKFTTLEIVLSVLLLVLFIISIVLIVLLAKESLKSTAPDPGTTGTPDPGTTGTP DPGTTGTTHARTTGPPDPGTTGTTPVSAECPVVNELERINCIPDQPPTKATCDQRGCCWN PQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGSNVDNVLLTAEYQTS NRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDS SIGPLLFADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLY GAQTFFLCLEDASGLSFGVFLMNSNAMEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVV QEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDVQHADIDYMDER RDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNS SDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGS VSGCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKT VFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIPMVGPDICG FALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLL PYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAY VPDAVWYDYETGSQVRWRKQKVEMELPGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGL IIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFN EIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWSIKIRD EEKIDCYPDENGASAENCTARGCIWEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADIS LKSSVYANAFPSTPVNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIPSMPSSTPEG QLYDVLIKKNPFGIEIRRKSTGTIIWDSQLLGFTFSDMFIRISTRLPSKYLYGFGETEHR SYRRDLEWHTWGMFSRDQPPGYKKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPL PALTYRTTGGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIA SLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSPKFAGFPALINRMKADGMRVILILDPAI SGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQVELYRAYV AFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCRDAS LNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAVQEV TGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGADICGFF QDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTLLPYLY TLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTAYFPRA RWYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEPALNTHLSRQKFMGFKIAL DDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYITGTNPLKLGYIE IWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNISLHNFTSLTWISTL NT seq 5574 nt NT seq  +upstreamnt  +downstreamnt atggcaagaaagaagctgaaaaaatttactactttggagattgtgctcagtgttcttctg cttgtgttgtttatcatcagtattgttctaattgtgcttttagccaaagagtcactgaaa tcaacagccccagatcctgggacaactggtaccccagatcctgggacaactggtacccca gatcctggaacaactggtaccacacatgctaggacaacgggtcccccagatcctggaaca actggtaccactcctgtttctgctgaatgtccagtggtaaatgaattggaacgaattaat tgcatccctgaccagccgccaacaaaggccacatgtgaccaacgtggctgttgctggaat ccccagggagctgtaagtgttccctggtgctactattccaagaatcatagctaccatgta gagggcaaccttgtcaacacaaatgcaggattcacagcccggttgaaaaatctgccttct tcaccagtgtttggaagcaatgttgacaatgttcttctcacagcagaatatcagacatct aatcgtttccactttaagttgactgaccaaaccaataacaggtttgaagtgccccacgaa cacgtgcagtccttcagtggaaatgctgctgcttctttgacctaccaagttgaaatctcc agacagccatttagcatcaaagtgaccagaagaagcaacaatcgtgttttgtttgactcg agcattgggcccctactgtttgctgaccagttcttgcagctctccactcgactgcctagc actaacgtgtatggcctgggagagcatgtgcaccagcagtatcggcatgatatgaattgg aagacctggcccatatttaacagagacacaactcccaatggaaacggaactaatttgtat ggtgcgcagacattcttcttgtgccttgaagatgctagtggattgtcctttggggtgttt ctgatgaacagcaatgccatggaggttgtccttcagcctgcgccagccatcacttaccgc accattgggggcattctcgacttctatgtgttcttgggaaacactccagagcaagttgtt caagaatatctagagctcattgggcggccagcccttccctcctactgggcgcttggattt cacctcagtcgttacgaatatggaaccttagacaacatgagggaagtcgtggagagaaat cgcgcagcacagctcccttatgatgttcagcatgctgatattgattatatggatgagaga agggacttcacttatgattcagtggattttaaaggcttccctgaatttgtcaacgagtta cacaataatggacagaagcttgtcatcattgtggatccagccatctccaacaactcttcc tcaagtaaaccctatggcccatatgacaggggttcagatatgaagatatgggtgaatagt tcagatggagtgactccactcattggggaggtctggcctggacaaactgtgtttcctgat tataccaatcccaactgtgctgtttggtggacaaaggaatttgagctttttcacaatcaa gtagagtttgatggaatctggattgatatgaatgaagtctccaactttgttgatggttcg gtctcaggatgttccacaaacaacctaaataatcccccattcactcccagaatcctggat gggtacctgttctgcaagactctctgtatggatgcagtgcagcactggggcaagcagtat gacattcacaatctgtatggctactccatggcggtcgccacagcagaagctgccaagact gtgttccctaataagagaagcttcattctgacccgttctacctttgcgggctctggcaag tttgcagcacattggttaggagacaacactgccacctgggatgacctgagatggtccatc cctggcgtgcttgagttcaacctttttggcatcccaatggtgggtcctgacatatgtggc tttgctttggacacccctgaggagctctgtaggcggtggatgcagttgggtgcattttat ccgttttctagaaatcacaatggccaaggctacaaggaccaggatcctgcctcctttgga gctgactccctgctgttgaattcctccaggcactaccttaacatccgctatactctattg ccctacctatacaccctcttcttccgtgctcacagccgaggggacacggtggccaggccc cttttgcatgagttctacgaggacaacagcacttgggatgtgcaccaacagttcttatgg gggcccggcctcctcatcactccagttctggatgaaggtgcagagaaagtgatggcatat gtgcctgatgctgtctggtatgactacgagactgggagccaagtgagatggaggaagcaa aaagtcgagatggaacttcctggagacaaaattggacttcaccttcgaggaggctacatc ttccccacacagcagccaaatacaaccactctggccagtcgaaagaaccctcttggtctt atcattgccctagatgagaacaaagaagcaaaaggagaacttttctgggataatggggaa acgaaggatactgtggccaataaagtgtatcttttatgtgagttttctgtcactcaaaac cgcttggaggtgaatatttcacaatcaacctacaaggaccccaataatttagcatttaat gagattaaaattcttgggacggaggaacctagcaatgttacagtgaaacacaatggtgtc ccaagtcagacttctcctacagtcacttatgattctaacctgaaggttgccattatcaca gatattgatcttctcctgggagaagcatacacagtggaatggagcataaagataagggat gaagaaaaaatagactgttaccctgatgagaatggtgcttctgccgaaaactgcactgcc cgtggctgtatctgggaggcatccaattcttctggagtccctttttgctattttgtcaac gacctatactctgtcagtgatgttcagtataattcccatggggccacagctgacatctcc ttaaagtcttccgtttatgccaatgccttcccctccacacccgtgaacccccttcgcctg gatgtcacttaccataagaatgaaatgctgcagttcaagatttatgatcccaacaagaat cggtatgaagttccagtccctctgaacatacccagcatgccatccagcacccctgagggt caactctatgatgtgctcattaagaagaatccatttgggattgaaattcgccggaagagt acaggcactataatttgggactctcagctccttggctttaccttcagtgacatgtttatc cgcatctccacccgccttccctccaagtacctctatggctttggggaaactgagcacagg tcctataggagagacttggagtggcacacttgggggatgttctcccgagaccagccccca gggtacaagaagaattcctatggtgtccacccctactacatggggctggaggaggacggc agtgcccatggagtgctcctgctgaacagcaatgccatggatgtgacgttccagcccctg cctgccttgacataccgcaccacagggggagttctggacttttatgtgttcttggggccg actccagagcttgtcacccagcagtacactgagttgattggccggcctgtgatggtacct tactggtctttggggttccagctgtgtcgctatggctaccagaatgactctgagatcgcc agcttgtatgatgagatggtggctgcccagatcccttatgatgtgcagtactcagacatc gactacatggagcggcagctggacttcaccctcagccccaagtttgctgggtttccagct ctgatcaatcgcatgaaggctgatgggatgcgggtcatcctcattctggatccagccatt tctggcaatgagacacagccttatcctgccttcactcggggcgtggaggatgacgtcttc atcaaatacccaaatgatggagacattgtctggggaaaggtctggcctgattttcctgat gttgttgtgaatgggtctctagactgggacagccaagtggagctatatcgagcttatgtg gccttcccagactttttccgtaattcaactgccaagtggtggaagagggaaatagaagaa ctatacaacaatccacagaatccagagaggagcttgaagtttgatggcatgtggattgat atgaatgaaccatcaagcttcgtgaatggggcagtttctccaggctgcagggacgcctct ctgaaccaccctccctacatgccacatttggagtccagggacaggggcctgagcagcaag accctttgtatggagagtcagcagatcctcccagacggctccctggtgcagcactacaac gtgcacaacctgtatgggtggtcccagaccagacccacatacgaagccgtgcaggaggtg acgggacagcgaggggtcgtcatcacccgctccacatttccctcttctggccgctgggca ggacattggctgggagacaacacggccgcatgggatcagctgaagaagtctatcattggc atgatggagttcagcctcttcggcatatcctatacgggagcagatatctgtgggttcttt caagatgctgaatatgagatgtgtgttcgctggatgcagctgggggccttttaccccttc tcaagaaaccacaacaccattgggaccaggagacaagaccctgtgtcctgggatgttgct tttgtgaatatttccagaactgtcctgcagaccagatacaccctgttgccatatctgtat accttgatgcataaggcccacacggagggcgtcactgttgtgcggcctctgctccatgag tttgtgtcagaccaggtgacatgggacatagacagtcagttcctgctgggcccagccttc ctggtcagccctgtcctggagcgtaatgccagaaatgtcactgcatatttccctagagcc cgctggtatgattactacacgggtgtggatattaatgcaagaggagagtggaagaccttg ccagcccctcttgaccacattaatcttcatgtccgtgggggctacatcctgccctggcaa gagcctgcactgaacacccacttaagccgccagaaattcatgggcttcaaaattgccttg gatgatgaaggaactgctgggggctggctcttctgggatgatgggcaaagcattgatacc tatgggaaaggactctattacttggccagcttttctgccagccagaatacgatgcaaagc catataattttcaacaattacatcactggtacaaatcctttgaaactgggctacattgaa atctggggagtgggcagtgtccccgttaccagtgtcagcatctctgtgagtggcatggtc ataacaccctccttcaacaatgaccccacgacacaggtattaagcatcgatgtgactgac agaaacatcagcctacataattttacttcattgacgtggataagcactctgtga

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