KEGG ORTHOLOGY: K12240

ORTHOLOGY: K12240

Entry

K12240                      KO

Symbol

pchF

Name

L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69]

Pathway

map01053

Biosynthesis of siderophore group nonribosomal peptides

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01053 Biosynthesis of siderophore group nonribosomal peptides
    K12240  pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K12240  pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF
Enzymes [BR:ko01000]
6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.69  L-cysteine---[L-cysteinyl-carrier protein] ligase
     K12240  pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF
Polyketide biosynthesis proteins [BR:ko01008]
Nonribosomal peptide synthetase (NRPS)
  Nonlinear NRPS
   Pyochelin synthetase
    K12240  pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF

Other DBs

COG:

COG1020

Genes

KMI:	VW41_14180

PGE:	LG71_13430

SYM:	K6K13_09575

YPE:

YPO0776

YPA:

YPA_3374

YPN:

YPN_3216

YPM:	YP_3425(entF3)

YPZ:

YPZ3_0722

YPT:	A1122_01155

YPD:

YPX:

YPW:

YPJ:

YPV:

YPL:

YPS:

YPO:

YPI:	YpsIP31758_0684

YPY:

YPB:

YPQ:

YPU:

YPR:

YPC:

YPF:

YSI:	BF17_03615

YFR:

AW19_774

YKR:

CH54_888

YEG:	PL78_04165

PCAC:

OI450_11540

PAO:	Pat9b_4773

PTT:	VY86_04720

XBV:

XBW1_1484

LANH:

KR767_17535

PAE:	PA4225(pchF)

PAEV:

N297_4357

PAEI:

N296_4357

PAU:	PA14_09280(pchF) PA14_54920

PAP:	PSPA7_0875(pchF)

PAG:	PLES_07021(pchF)

PAF:	PAM18_0712(pchF)

PNC:	NCGM2_5470(pchF)

PAEB:

NCGM1900_0734(pchF)

PDK:	PADK2_03545

PSG:	G655_03580

PRP:	M062_22260

PAEP:

PAER:

PAEM:

PAEL:

PAES:

PAEU:

BN889_04699(pchF)

PAEG:

PAEC:

PAEO:

PPAA:

PFL:	PFL_3492(pchF)

PPRC:

PFLCHA0_c35330(irp1)

PPRO:

PPC_3646(pchF)

PFB:

VO64_5522

PVR:	PverR02_15525

PAZO:

AYR47_21960

PFW:	PF1751_v1c25800

PFF:	PFLUOLIPICF724130

PCZ:	PCL1606_27870

PSEM:

TO66_16985

PSOS:

POS17_3635(pchF)

PSEP:

C4K39_5485

PSAM:

HU731_027795

PZA:	HU749_012685

EMO:	DM558_05695

PSEN:

PNC201_20480(mbtB)

MII:	BTJ40_11110

MEC:

MPUR:

SAJS:

ADI:

CHRO:

AQL:	BXU06_11810

RSO:

RSc1811

RSE:

F504_1578

RPU:	CDC45_09320

RNC:	GO999_08685

RSL:	RPSI07_1867

RSM:	CMR15_11817

BPS:	BPSS0587(pchF)

BPM:	BURPS1710b_A2151(pchF)

BPL:	BURPS1106A_A0788

BPD:	BURPS668_A0878

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_II0647(pchF)

BPQ:	BPC006_II0833

BPK:

BPSH:

BPSA:

BPSO:

BUT:

BTE:	BTH_II1827

BTQ:

BTJ:

BTZ:

BTV:

BTHE:

BTHM:

BTHA:

BTHL:

BUR:	Bcep18194_B0673

BCM:	Bcenmc03_5290

BCH:	Bcen2424_4997

BCEO:

I35_6120(pchF)

BCED:

BCEP:

BSEM:

BSTL:

BARI:

BGD:	bgla_4p2140

BGP:	BGL_1c20570(pchF)

BPLA:

bpln_1g19090

OTD:	J1M35_10305

HRB:	Hrubri_2237

BRK:	CWS35_16345

RPC:

RPC_3032

SECH:

B18_04270

ALI:	AZOLI_p20161(pchF)

HJO:	AY555_10640

DEO:	CAY53_00285

SCU:	SCE1572_43415

LYB:	C3943_18865

LPAK:

GDS87_10285

LMAC:

I6G82_03570

BLR:	BRLA_c037020

BFM:	BP422_17845

BAGR:

BA6348_08945

BRW:	GOP56_10725

BPAB:

PSE45_20770

SANC:

SANR_1291

FHM:	R0V13_03420

CKL:

CKL_1511

CKR:

CKR_1405

CSB:	CLSA_c16940(irp2)

CLD:	CLSPO_c23060

CAUN:

CLAUR_026160(dltA_6)

RPAY:

P0092_11095

RAL:	Rumal_0885

DSY:

DSY2821

DHD:

Dhaf_3965

DAE:

Dtox_2674

BPRO:

PMF13cell1_00657(mbtB_1)

ACAC:

EYQ97_15755

EHL:

EHLA_1441

RTO:	RTO_11580 RTO_12320

CBOL:

CGC65_09170

SINT:

K5I26_14510

VGU:	HYG85_16695

AVG:	I6H45_03220

PFT:

JBW_03609

MANA:

MAMMFC1_02828(mbtB_2)

STED:

SPTER_12030(mbtB_1)

EYY:	EGYY_00410(EntF) EGYY_29280(EntF)

AEQ:

AHAT:

MPA:

MAVI:

MAVU:

MPAG:

CDH:	CDB402_1084(irp2C)

CDZ:	CD31A_2083(irp2C)

CDS:	CDC7B_2042(irp2C)

CDD:	CDCE8392_1964(irp2C)

CDIP:

ERS451417_02094(irp2C)

CSX:	CSING_01210(irp2C)

CSP:

WM42_1816

NFR:	ERS450000_00763(mbtB_1)

NCY:	NOCYR_2585

NNO:	NONO_c49320

NOD:	FOH10_15025

NWL:	NWFMUON74_24310

NIE:	KV110_22875 KV110_35845

CBQ:	AL705_04305

SCO:	SCO7683(SC4C2.18)

SCB:

SCAB_1471

SSX:	SACTE_0740

SRC:	M271_09960

SVE:

SVEN_0517

SLV:	SLIV_00885

SGU:	SGLAU_04465(nrps1B) SGLAU_04640(nrps1D)

STRE:

GZL_p00202

SPHW:

NFX46_19160

SLS:	SLINC_1332

STRD:

NI25_03970

SNQ:	CP978_29875

SPAD:

DVK44_09635

SPAC:

B1H29_04830

SHUN:

DWB77_06824(mbtB_1)

SHAR:

SFEU:

SROI:

STUB:

SYUN:

SCOA:

YIA:	LO772_01875

CMI:	CMM_0330(npsB)

CMH:	VO01_01490

CMC:	CMN_00301(npsB)

CCAF:

FGD68_03585

HMM:	R3I40_10080

DCO:	SAMEA4475696_1592(mbtB_3)

PACD:

EGX94_02945

PAUS:

NCTC13651_00740(mbtB_1)

THAO:

NI17_005435

TALX:

FOF52_04705

NDA:	Ndas_1030 Ndas_1761

NEX:	NE857_12315

NAKE:

KGD83_20620

NCG:	KGD84_12930

SNAH:

ACTW:

ACTQ:

SRO:

SACG:

SACC:

EYD13_12025(mbtB1)

AORI:

SD37_07330 SD37_10150

PHH:	AFB00_19555

PAUT:

Pdca_37550

KBU:	Q4V64_43930

AHM:	TL08_14435

ACTU:

Actkin_03287(angR)

CROS:

N8J89_28075

STP:	Strop_2820

VMA:	VAB18032_07015

MCRA:

ID554_27815

VER:	HUT12_19180

MFEU:

H1D33_21235

ASE:	ACPL_6139(nrps2A)

ACTS:

ACWT_6007

AOU:	ACTOB_004317

PRY:	Prubr_62260

AMAS:

QU670_12580

» show all

Reference

PMID:10555976

Authors

Quadri LE, Keating TA, Patel HM, Walsh CT

Title

Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.

Journal

Biochemistry 38:14941-54 (1999)
DOI:10.1021/bi991787c

Sequence

[pau:PA14_09280]

LinkDB

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