Actinoplanes sp. SE50/110: ACPL_6139
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Entry
ACPL_6139 CDS
T02044
Symbol
nrps2A
Name
(GenBank) Tyrocidine synthetase 3
KO
K12240
L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:
6.2.1.69
]
Organism
ase
Actinoplanes sp. SE50/110
Pathway
ase01053
Biosynthesis of siderophore group nonribosomal peptides
Brite
KEGG Orthology (KO) [BR:
ase00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01053 Biosynthesis of siderophore group nonribosomal peptides
ACPL_6139 (nrps2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
ase01008
]
ACPL_6139 (nrps2A)
Enzymes [BR:
ase01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.69 L-cysteine---[L-cysteinyl-carrier protein] ligase
ACPL_6139 (nrps2A)
Polyketide biosynthesis proteins [BR:
ase01008
]
Nonribosomal peptide synthetase (NRPS)
Nonlinear NRPS
Pyochelin synthetase
ACPL_6139 (nrps2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
Methyltransf_12
Thioesterase
AMP-binding_C
TubC_N
PP-binding
Methyltransf_23
Methyltransf_11
Methyltransf_25
Abhydrolase_1
Methyltransf_31
DLH
Ubie_methyltran
Methyltransf_24
Motif
Other DBs
NCBI-ProteinID:
AEV87024
UniProt:
G8SKZ9
LinkDB
All DBs
Position
6727872..6733349
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AA seq
1825 aa
AA seq
DB search
MAIVETVAALRAAGMVLYAEGDDLRYQAPKGVATPERLRWLRDHKPDVLAVLRADGDEFG
GPLAADPERAGEPFPLTEVQSAYLLGRGSAFEFGGVACHGYLELAVPDWPVHEVEAAWNR
LVARHAMLRATVAAEGFQQVAAEVPHYPVAHADLRDAGPEAVREAIATVREQLSHRVRPT
DRWPLFDLRATSTPDGLLLHFSIDLLICDYSSFRLLLDELRREVTGEGGDAAPAVTFRDY
VLALQGIGETERHRRDREYWFSRVDELPPAPELPVRADAPLAAPHFTRFATRLAGPRWQQ
LHRRATDLGITASTAVLGAYAETIGRWSRHPRFTLSLTVQNRLPLHPDVARVIGDFSSVS
LLDVDTTPVAAFGERLATLHGRLWQDLDHRLCGGVEVLREIARRRGRAAAALPVTFTSTV
SGAPTPGAGLMPGARLRYGISQTPQVWIDCQMMAEDGGLLLHWDVRDGVLPDGVAADMFA
AFTELVERLADGDAVDEADPVVLPRRQRELVAAANDTAEPRVRGPLHAAFLDRARRDPGR
VAVIAAGCTLTYGELLARAESLAGLLRDAGCEPGERVGVVAPKGADQVVAVLGILLAAAA
YLPVDLGQPARRRDTILRDAGARFVVTDAVHAGELAGSGVVTIEADRLPATPARPAEAPG
PVGGDLAYVIYTSGSTGTPKGVMISHEAARNTVDDINRRFGVGADDRVLGLAQLGFDLSV
YDVFGPLSVGGALVLPQAERRGDPSHWAELMVTERVSVWNSVPAQMQLLTEYLAAAPGHD
LSRLRVVMLSGDWIPVTLPDTVRRHAPSAEVISLGGATEASIWSIHHRVGAVDPDQPSIP
YGRPLANQSFHVFDDVLRECPELVVGELYIGGAGVALGYLGDAARTAERFVDHPRDGRRL
YRTGDLGRRLPDGEIEFLGREDGQIKIRGHRIEVAEIEAALLAHPGVQAAAVIPYDDEAG
RHLAAFVEPAAADRAPLPERLPETMAAAAAARIGAVDRGRVAEMVELLDRAALQSISRLL
VDCGLFAGVGSRHSDQEIIETVKAAPANHYLVRRWLGALEHEGLVRRDPDTGAYHGLTRP
DEAAAKRLRDRVDVLEPAVRWGAELVRYHRTSEENLQALVRNDIDLKTLLFPHGRLDTAE
AAYRDNLISRYNNAAVIAALRTIATGHSGGGPLRILEIGAGVGGTSTELIPALDDLAVEY
LFTDLSHFFLNAAAERFAAYPWVRFGLFDLNADHVEQQMPDNGFDVILLANVLHNAVHAG
RALELLKGLVRPGGWLVFIEATRDAYHVMTSMEFNAGLTGFEDERRETGTTFVPRDRWLS
LLDEAGAEVVATLPAADDALSLIGQHVFVSRFKADRAPVEVADVQRHLAERLPEYMLPAQ
LHTLDRIPLTGNAKVDRGRLARWTVRGGRHAAGSAASAPADETERLLADIWCAILPVTRI
GRDTDFFAAGGDSLLVAQLVGRIRDRVPAARDVEWDHLLRRVLNRPTIADIAAYLRSLES
SGPAPAPSSLVSVGDRARRPAAGPGQPLHVLVHDGTGTLIPYRALVRELSPDVPMAGLVL
DDEQEYLDSDPHTLTGTLARRHAATLVAAGHEEVHLIGYCMGGLLVTELATRLTAAGIRV
AATTIVSSYRVPYLVEDDLLAEYIFARVMRADPIRLGYPADETETRRIVAGAVARHGGRV
PEGSLLEPGENGVRPETVAGFRRLAAMDPDERLTAIGAAMPVSDAGLTSVDRLRRQFRIV
KHSLVAVASHRPTPYDGPVTFVRQSGEAQVFPGMHRDMSDYWRDVCTGELRIVDVPGDHF
TCMRPPNVPAVARAVRLAVPRGEHA
NT seq
5478 nt
NT seq
+upstream
nt +downstream
nt
atggccattgtggagacggtggcggccctgcgggcggccggcatggtgctgtacgccgag
ggcgacgacctccgctatcaggcgccgaagggcgtggccaccccggaacggctgcgctgg
ctgcgtgaccacaaaccggacgtcctggcggtgctgcgcgcggacggcgacgagttcggc
ggcccgctcgccgccgaccccgagcgggccggcgagccgttcccgctgaccgaggtgcag
tcggcgtatctgctcggccggggcagcgcgttcgagttcggcggggtggcctgccacggt
tacctggagctggccgtcccggactggccggttcacgaggtggaggcggcctggaaccga
ctggtggcccggcacgccatgctccgcgcgaccgtcgcggccgagggattccagcaggtc
gcggccgaggtgccccattacccggtcgcacacgcggatctgcgtgacgccgggccggag
gcggtccgggaggcgatcgccaccgtgcgcgagcagctgtcccaccgggtgcggcccacc
gatcggtggccgctgttcgatctgcgcgcgaccagcacacccgacggtctgctgctgcac
ttctcgatcgacctgctgatctgcgactacagcagcttccggctgctgctggacgagctg
cggcgcgaggtgaccggcgagggcggcgacgccgcgccggccgtcaccttccgcgactac
gtcctggccctgcagggcatcggggagacggaacgtcaccggcgcgaccgtgagtactgg
ttcagccgggtcgacgagctgccgcccgcgcccgagctgccggtccgcgcggacgcgcca
ctcgcggcgccgcacttcacccgcttcgccacccggctggccgggccccgctggcagcaa
ctgcaccggcgcgcgaccgacctggggatcaccgcctccaccgcggtgctgggcgcctac
gccgagacgatcgggcggtggagccgccacccccgtttcaccctgagcctgaccgtgcag
aaccggctgccactgcacccggacgtggcccgggtcatcggcgacttcagctcggtcagc
cttctggacgtggacacgaccccggtcgcggcgttcggcgagcgtctggccaccctgcac
ggacggctgtggcaggacctcgatcaccgcctctgcggcggcgtcgaggtgctgcgggag
atcgcgcgccgccggggccgggcggccgcggccctgccggtgacgttcaccagcacggtg
agcggcgccccgacgcccggcgccggcctgatgccgggagcgcgcctgaggtacgggatc
agccagacgccgcaggtgtggatcgactgccagatgatggcggaggacggcggcctgctg
ctgcactgggacgtccgggacggcgtcctgcccgacggggtcgccgccgacatgttcgcc
gccttcaccgagctcgtcgagcggctcgccgacggtgacgccgtcgacgaggcggacccg
gtcgtgctgccccgccggcagcgggagctggtggccgcggccaacgacaccgccgagccg
cgggtgcgcgggcccctgcacgcggcgttcctggaccgggcgcgccgcgaccccggacgg
gtcgccgtgatcgcggccgggtgcacgctgacctacggcgagctgctcgcccgggccgag
tcgctggccgggctgctgcgcgacgccgggtgcgagccgggcgagcgggtcggggtcgtc
gcccccaagggcgcggaccaggtcgtggcggtgctgggaatcctgctcgccgcggccgcc
tacctgccggtcgatctggggcaaccggcccggcggcgggacacgatcctgcgcgacgcc
ggggcccggttcgtcgtcaccgacgcggtccacgccggggagctggccgggtcgggcgtg
gtcacgatcgaggcggatcggctgcccgcgacaccggcccggccggccgaggcgcccggg
cccgtcgggggcgacctggcgtacgtcatctacacctcggggtccaccgggacgcccaag
ggcgtcatgatcagccacgaggcggcccgcaacacggtcgacgacatcaaccggcgcttc
ggcgtcggcgccgacgaccgggtcctcgggctcgcgcagctcggcttcgacctgtcggtc
tacgacgtgttcggcccgttgtcggtgggcggcgccctggtgctgccgcaggccgaacgg
cgcggggacccgtcgcactgggccgagttgatggtcaccgagcgggtcagcgtgtggaac
tcggtgcccgcccagatgcagctgttgaccgagtatctggcggcggcgcccggccacgac
ctgagccggctgcgggtggtcatgctctccggcgactggatcccggtcaccctgcccgac
accgtgcgccgccacgccccctcggccgaggtgatcagcctgggcggggcgaccgaagcc
tcgatctggtcgattcaccaccgtgtcggcgcggtcgacccggaccagccgagcatcccg
tacggccgaccgctggccaaccagagcttccacgtcttcgacgacgtgctgcgggagtgc
ccggagctggtggtcggcgagctgtacatcggcggcgccggcgtggccctcggctacctc
ggcgacgcggcgcgcacggccgaacggttcgtcgaccacccgcgcgacggacggcggctg
taccgcaccggcgacctcggccggcggcttcccgacggggagatcgagttcctcgggcgc
gaggacggccagatcaagatccgcgggcaccgcatcgaggtcgccgagatcgaggcggca
ctgctcgcccaccccggagtgcaggcggccgcggtgatcccgtacgacgacgaggccgga
cgccatctcgccgccttcgtcgaacccgcggcggcggaccgcgccccgctgccggagcgg
ctgcccgagaccatggccgcggcggccgcggcgcgcatcggcgccgtcgaccggggtcgg
gtcgccgagatggtggagctgctcgaccgtgccgccctgcagtcgatcagccgactgctg
gtggactgcgggctgttcgccggtgtcgggagccggcacagcgaccaggagatcatcgag
acggtcaaggccgctccggcgaaccattatctggtgcgacgatggctgggcgccctggag
cacgagggcctcgtccgacgggacccggacaccggcgcgtaccacggcctgacccggccg
gacgaggccgcggcgaagcgcctgcgggaccgcgtcgacgtcctggaaccggccgtccgg
tggggcgccgagctggtgcgctatcaccggacctccgaggagaacctgcaggcgctggtc
cgcaacgacatcgacctcaagacgctgctgttcccgcacgggcggctcgacaccgccgag
gccgcgtaccgcgacaacctgatcagccgctacaacaacgcggccgtcatcgccgcgctg
cgcacgatcgccaccgggcactccggcggtggcccgctgcggatcctggagatcggcgcc
ggggtcggcggcaccagcaccgagctgatccccgcgctggacgacctcgccgtcgagtac
ctgttcaccgacctctcgcacttcttcctcaatgcggcggccgagcgcttcgcggcctac
ccctgggtccggttcgggctgttcgatctcaacgccgaccacgtcgagcagcagatgccg
gacaacgggttcgacgtgatcctgctggccaacgtgctgcacaacgcggtgcacgccggc
cgggcgctggagctgctgaaggggttggtgcggcccggtggctggctcgtcttcatcgag
gccacccgcgacgcgtaccacgtgatgacctcgatggagttcaatgccgggctcaccggg
ttcgaggacgagcggcgggagaccgggaccacgttcgtgccccgcgaccggtggctgtcc
ctgctcgacgaggccggcgccgaggtggtggccacactgccggccgccgacgacgccctg
tcgctgatcgggcaacacgtcttcgtgtcccggttcaaggccgaccgcgcgccggtggag
gtcgcggacgtacagcggcacctggccgaacgcctgccggagtacatgcttccggcccag
ctgcacaccctcgaccggatcccgctgaccggcaacgccaaggtggaccgcgggcggctg
gcccggtggacggtccgcggcgggcggcacgcggccggctcggcggcgtcggcgcccgcc
gacgagaccgaacggctgctggccgacatctggtgcgcgatcctgccggtcacccggatc
ggccgggacaccgacttcttcgccgcgggtggcgactcgctgctcgtcgcccagctggtc
gggcggatccgggaccgggtgccggccgcccgcgacgtcgagtgggaccacctgctgcgc
cgggtgctgaaccggccgacgatcgccgacatcgcggcctacctgcgctcgctcgagtcg
tccgggccggcgccggccccgtcgtcgctggtctccgtgggcgaccgggcccgccggccc
gccgccggccccgggcagccgctgcatgtgctcgtgcacgacggcaccggcaccctgatc
ccctaccgggcgctggtccgggagctctcccccgacgtgccgatggccggcctcgtcctc
gacgacgagcaggagtacctcgacagcgacccgcacacgctgaccggcacgctggcccgg
cggcacgccgccaccctggtcgcggccggccacgaggaggtccacctgatcggttactgc
atgggcgggctgctcgtcaccgagctggccacccggctgacggcggccggcatccgggtc
gccgcgaccacgatcgtcagcagttaccgggtgccctacctggtcgaggacgacctgctg
gccgagtacatcttcgcccgggtgatgcgagccgacccgatccggctcggttacccggcc
gacgagaccgagacccggcggatcgtcgccggggcggtcgcccgccacggcgggcgggtc
ccggagggcagcctgctcgagccgggtgaaaacggcgtacgcccggagacggtcgccgga
ttccggcgcctggccgcgatggaccccgatgagcggctgaccgcgatcggggcggccatg
ccggtctccgacgccgggctgacctccgtggaccggctgcgccgccagttccggatcgtc
aagcacagcctggtcgcggtcgcctcgcaccggcccacgccgtacgacggtccggtgacc
ttcgtccggcagagcggtgaggcgcaggtcttcccggggatgcaccgcgacatgagcgac
tactggcgcgacgtgtgcaccggtgagctgcgcatcgtcgacgttcccggtgatcacttc
acctgcatgcgaccaccgaacgtgccggccgtggcccgggccgtgcgcctcgccgtgccg
cggggcgagcatgcgtga
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