KEGG ORTHOLOGY: K12560

ORTHOLOGY: K12560

Entry

K12560                      KO

Symbol

FCGR2B, CD32

Name

low affinity immunoglobulin gamma Fc receptor II-b

Pathway

map03265

Virion - Ebolavirus, Lyssavirus and Morbillivirus

map04145

Phagosome

map04380

Osteoclast differentiation

map04662

B cell receptor signaling pathway

map04666

Fc gamma R-mediated phagocytosis

map05150

Staphylococcus aureus infection

map05152

Tuberculosis

map05162

Measles

Disease

H00080

Systemic lupus erythematosus

H00361

Malaria

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09125 Information processing in viruses
   03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
   04666 Fc gamma R-mediated phagocytosis
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
   05152 Tuberculosis
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Fc receptors
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
CD molecules [BR:ko04090]
Proteins
  K12560  CD32b, FCGR2B; Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Other DBs

GO:

0019770

Genes

HSA:	2213(FCGR2B)

PTR:

748765

PPS:	100984838(FCGR2B)

GGO:	101128757(FCGR2B)

PON:	100453137(FCGR2B)

PPYG:

129036201(FCGR2B)

NLE:	101176250(FCGR2B)

HMH:	116473326(FCGR2B)

SSYN:

134734476(FCGR2B)

MCC:	720009(FCGR2B)

MCF:	102139530(FCGR2B)

MNI:	105498217(FCGR2B)

CSAB:

103223672(FCGR2B)

CATY:

105589236(FCGR2B)

PANU:

101011136(FCGR2B)

TGE:	112609495(FCGR2B)

MLEU:

105551011(FCGR2B)

RRO:	104670387(FCGR2B)

RBB:	108542588(FCGR2B)

TFN:	117074577(FCGR2B)

PTEH:

111533804(FCGR2B)

CANG:

105519601(FCGR2B)

CJC:	100412558(FCGR2B)

SBQ:	101039367(FCGR2B)

CIMI:

108293620(FCGR2B) 108302361

ANAN:

105715304(FCGR2B) 105732474

CSYR:

103277310(FCGR2B)

MMUR:

105873560(FCGR2B)

LCAT:

123635230

PCOQ:

105806465(FCGR2B)

OGA:	100958885(FCGR2B)

MMU:	14130(Fcgr2b)

MCAL:

110299221

MPAH:

110321728

RNO:	289211(Fcgr2b)

MCOC:

116103280

ANU:	117712635(Fcgr2b)

MUN:	110554428(Fcgr2b)

CGE:

103161893

MAUA:

101844813(Fcgr2b)

PROB:

127223559(Fcgr2b)

PLEU:

114689890(Fcgr2b)

MORG:

121442022 121455099

MFOT:

126511148

AAMP:

119827205(Fcgr2b)

NGI:	103746773(Fcgr2b)

HGL:	101704179(Fcgr2b)

CPOC:

100192391(Fcgr2b)

CCAN:

109693504(Fcgr2b)

DORD:

105996454

DSP:

122109326

PLOP:

125359219(Fcgr2b)

NCAR:

124993135 124993151

MMMA:

107147460

OCU:

100359306

OPI:	101523293(FCGR2B)

TUP:	102500089(FCGR2B)

CFA:	100856270(FCGR2B)

CLUD:

112643042(FCGR2B)

VVP:	112914296(FCGR2B)

VLG:	121472254(FCGR2B)

NPO:	129515369(FCGR2B)

AML:

100479420

UMR:	103658249(FCGR2B)

UAH:

113268760

UAR:	123783523(FCGR2B)

MNP:

132025750

MLK:

131814734

NVS:	122918381(FCGR2B)

ORO:	101363428(FCGR2B)

EJU:	114210517(FCGR2B)

ZCA:

113933575

MLX:	118014025(FCGR2B)

NSU:	110588143(FCGR2B)

LWW:	102736172(FCGR2B)

FCA:	101087550(FCGR2B)

PYU:	121020941(FCGR2B)

PBG:

122475591

PVIV:

125155527

LRUF:

124509903

PTG:	102959619(FCGR2B)

PPAD:

109276672(FCGR2B)

PUC:

125925565

AJU:

106986772

HHV:	120241067(FCGR2B)

BTA:	282229(FCGR2B)

BOM:

102273069

BIU:	109578097(FCGR2B)

BBUB:

102394636

BBIS:

104999183(FCGR2B)

CHX:

102186356

OAS:	100192432(FCGR2B)

BTAX:

128044371(FCGR2B)

ODA:

120855416

CCAD:

122430161(FCGR2B)

MBEZ:

129541246(FCGR2B)

SSC:	613131(FCGR2B)

CFR:

102516047

CBAI:

105068021(FCGR2B)

CDK:	105092686 116151293

VPC:

BACU:

BMUS:

LVE:

OOR:

PCAD:

PSIU:

116758779(FCGR2B)

NASI:

112403897(FCGR2B) 112403899

ECB:

102150150

EPZ:	103555970(FCGR2B)

EAI:

MYB:

MYD:

MMYO:

MDT:	132220311(FCGR2B)

EFUS:

103296486(FCGR2B)

MNA:

107535132

DRO:	112297192(FCGR2B)

SHON:

118979067(FCGR2B)

AJM:	119052404(FCGR2B)

PDIC:

114489494

PHAS:

123818559(FCGR2B)

MMF:	118637095(FCGR2B)

PPAM:

129082081

HAI:	109392296(FCGR2B)

RFQ:	117014583(FCGR2B)

PALE:

PGIG:

PVP:

RAY:

TOD:	119241334(FCGR2B)

SARA:

SETR:

LAV:

TMU:

ETF:	101660247(FCGR2B)

DNM:	101417741(FCGR2B)

MDO:	100015202 100619042(FCGR2B)

GAS:	123243617 123245384

SHR:	100924400(FCGR2B)

AFZ:

127562999

PCW:

110209906

TVP:	118845296 118845435 118845847 118845849 118847905

SCAN:

108964832

PMOA:

120506099 120506298

ZLE:	135441826 135461038 135461132 135461174 135461221

BBUF:

120982450

MZE:	101479608 112430766 112431154

ONL:

102079358

OAU:	116314316 116321146 120436245 120439145

CVG:	107104243 107105095

SASA:

106577810 106608912

SALP:

112070016

ELS:	105006757 114830263

» show all

Reference

PMID:9232445

Authors

Sarmay G, Koncz G, Pecht I, Gergely J

Title

Fc gamma receptor type IIb induced recruitment of inositol and protein phosphatases to the signal transductory complex of human B-cell.

Journal

Immunol Lett 57:159-64 (1997)
DOI:10.1016/S0165-2478(97)00055-2

Sequence

[hsa:2213]

Reference

PMID:20385827

Authors

Willcocks LC, Carr EJ, Niederer HA, Rayner TF, Williams TN, Yang W, Scott JA, Urban BC, Peshu N, Vyse TJ, Lau YL, Lyons PA, Smith KG

Title

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus.

Journal

Proc Natl Acad Sci U S A 107:7881-5 (2010)
DOI:10.1073/pnas.0915133107

Sequence

[hsa:2213]

Reference

PMID:2531080

Authors

Stuart SG, Simister NE, Clarkson SB, Kacinski BM, Shapiro M, Mellman I

Title

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

Journal

EMBO J 8:3657-66 (1989)
DOI:10.1002/j.1460-2075.1989.tb08540.x

Sequence

[hsa:2213]

LinkDB

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