KEGG ORTHOLOGY: K12755

ORTHOLOGY: K12755

Entry

K12755                      KO

Symbol

MYL9

Name

myosin regulatory light chain 9

Pathway

map04022

cGMP-PKG signaling pathway

map04024

cAMP signaling pathway

map04270

Vascular smooth muscle contraction

map04360

Axon guidance

map04510

Focal adhesion

map04520

Adherens junction

map04530

Tight junction

map04670

Leukocyte transendothelial migration

map04810

Regulation of actin cytoskeleton

map04814

Motor proteins

map04820

Cytoskeleton in muscle cells

map04921

Oxytocin signaling pathway

map05131

Shigellosis

map05132

Salmonella infection

Disease

H01869

Megacystis microcolon intestinal hypoperistalsis syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K12755  MYL9; myosin regulatory light chain 9
   04022 cGMP-PKG signaling pathway
    K12755  MYL9; myosin regulatory light chain 9
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12755  MYL9; myosin regulatory light chain 9
   04520 Adherens junction
    K12755  MYL9; myosin regulatory light chain 9
   04530 Tight junction
    K12755  MYL9; myosin regulatory light chain 9
  09142 Cell motility
   04814 Motor proteins
    K12755  MYL9; myosin regulatory light chain 9
   04820 Cytoskeleton in muscle cells
    K12755  MYL9; myosin regulatory light chain 9
   04810 Regulation of actin cytoskeleton
    K12755  MYL9; myosin regulatory light chain 9
09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    K12755  MYL9; myosin regulatory light chain 9
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    K12755  MYL9; myosin regulatory light chain 9
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K12755  MYL9; myosin regulatory light chain 9
  09158 Development and regeneration
   04360 Axon guidance
    K12755  MYL9; myosin regulatory light chain 9
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12755  MYL9; myosin regulatory light chain 9
   05131 Shigellosis
    K12755  MYL9; myosin regulatory light chain 9
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12755  MYL9; myosin regulatory light chain 9
   04147 Exosome
    K12755  MYL9; myosin regulatory light chain 9
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12755  MYL9; myosin regulatory light chain 9
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of hepatic cells
   K12755  MYL9; myosin regulatory light chain 9

Genes

HSA:	10398(MYL9)

PTR:	458216(MYL9)

PPS:	100995742(MYL9)

GGO:	101138103(MYL9)

PON:	100172462(MYL9)

PPYG:

129021608(MYL9)

NLE:	100593242(MYL9)

HMH:	116460758(MYL9)

SSYN:

129474175(MYL9)

MCC:	709784(MYL9)

MCF:	102135642(MYL9)

MTHB:

126964307

MNI:	105482353 105496295(MYL9)

CSAB:

103216486(MYL9)

CATY:

105582343(MYL9)

PANU:

101002500(MYL9)

TGE:	112632688(MYL9)

MLEU:

105533817(MYL9)

RRO:	104680548(MYL9)

RBB:	108523051(MYL9)

TFN:	117068731(MYL9)

PTEH:

111548199(MYL9)

CANG:

105502533(MYL9)

CJC:	100402498 100409239(MYL9)

SBQ:	101037608(MYL9) 101040386

CIMI:

108291105(MYL9) 108299165

ANAN:

105719168(MYL9)

CSYR:

103249472 103274606(MYL9)

MMUR:

105865848(MYL9)

LCAT:

123622378(MYL9)

PCOQ:

105804941(MYL9)

OGA:	100940607(MYL9)

MMU:	98932(Myl9)

MCAL:

110285279(Myl9)

MPAH:

110318312(Myl9)

RNO:	296313(Myl9)

MCOC:

116091273(Myl9)

ANU:	117704222(Myl9)

ASYL:

127686158(Myl9)

MUN:	110556939(Myl9)

CGE:	100753477(Myl9)

MAUA:

101837553(Myl9)

PROB:

127224759(Myl9)

PLEU:

114681851(Myl9)

MORG:

121460155(Myl9)

MFOT:

126507081

AAMP:

119814192(Myl9)

NGI:	103740213(Myl9) 103748521

HGL:	101716487(Myl9)

CPOC:

100725728(Myl9)

CCAN:

109700175

DORD:

105981786(Myl9)

DSP:	122120489(Myl9)

PLOP:

125353445(Myl9)

NCAR:

124977953

MMMA:

107138444(Myl9)

ITI:	101965744(Myl9)

OCU:

100343384

OPI:	101535284(MYL9)

TUP:	102483320(MYL9)

GVR:	103586929(MYL9)

CFA:	485856(MYL9)

CLUD:

112673894(MYL9)

VVP:	112928190(MYL9)

VLG:	121477909 121477910

NPO:	129493897(MYL9) 129503326

AML:	100465571(MYL9)

UMR:	103669791(MYL9)

UAH:	113258556(MYL9)

UAR:	123796948(MYL9)

ELK:

111141363

LLV:

125108508

MPUF:

101679631(MYL9)

MNP:	132021891(MYL9)

MLK:	131807732(MYL9)

NVS:	122916104(MYL9)

ORO:	101362788(MYL9)

EJU:	114220729(MYL9)

ZCA:	113937046(MYL9)

MLX:	118011444(MYL9)

NSU:	110579699(MYL9)

LWW:	102733307(MYL9)

FCA:	101097882(MYL9)

PYU:	121012246(MYL9)

PCOO:

112868836(MYL9)

PBG:	122496318(MYL9)

PVIV:

125161739(MYL9)

LRUF:

124503723

LGF:	123580264(MYL9)

AJU:

106979297

PTG:	102964789(MYL9)

PPAD:

109272490(MYL9)

PUC:

125936652

PLEZ:

122215590(MYL9)

HHV:	120228602(MYL9)

BTA:	505964(MYL9)

BOM:	102265044(MYL9)

BIU:	109567416(MYL9)

BBUB:

102390609(MYL9)

BBIS:

104980481(MYL9)

CHX:	102178087(MYL9)

OAS:	101121534(MYL9)

BTAX:

128058295(MYL9)

CSUM:

138091261(MYL9)

ODA:	120868649(MYL9)

CCAD:

122437006 122447927(MYL9)

MREE:

136159560(MYL9)

OVR:	110136382(MYL9)

MBEZ:

129563114(MYL9)

SSC:	100157760(MYL9)

CFR:	102517225(MYL9)

CBAI:

105073508(MYL9)

CDK:	105084979(MYL9)

VPC:	102530350(MYL9)

BACU:

103009483(MYL9)

BMUS:

118881813(MYL9)

LVE:	103077228(MYL9)

OOR:	101270950(MYL9)

LALB:

132504920(MYL9)

DLE:	111184217(MYL9)

PCAD:

102985793(MYL9)

PSIU:

116740323(MYL9)

NASI:

112398590(MYL9)

ECB:	100055199(MYL9)

EPZ:	103557622(MYL9)

EAI:	106835045(MYL9) 106836515

MYB:	102243369 102251806 102253999(MYL9)

MYD:	102752273(MYL9) 102769087

MMYO:

118660682 118663386(MYL9)

MLF:	102422575(MYL9)

MDT:	132239578(MYL9)

MYUM:

138993978 139013865(MYL9)

PKL:	118707702(MYL9)

EFUS:

103293324(MYL9)

MNA:	107542167(MYL9) 107544330

DRO:	112303838(MYL9)

SHON:

118985434(MYL9)

AJM:	119063288(MYL9)

PDIC:

114506335(MYL9)

PHAS:

123815319(MYL9)

MMF:	118619007(MYL9)

PPAM:

129070464(MYL9) 129083566

HAI:	109389577(MYL9)

RFQ:	117015642(MYL9)

PALE:

102886777(MYL9)

PGIG:

120603622(MYL9)

PVP:	105296470(MYL9)

RAY:	107512613(MYL9)

MJV:	108387031(MYL9)

TOD:	119233363(MYL9)

SARA:

101539003(MYL9)

SFUM:

130030254(MYL9)

SETR:

126017460(MYL9)

LAV:	100672436(MYL9)

TMU:

101346277

ETF:	101664182(MYL9)

DNM:	101426465(MYL9)

MDO:	100028971(MYL9)

GAS:	123235449(MYL9)

SHR:	100917897(MYL9)

AFZ:

127550375

PCW:	110216721(MYL9)

TVP:	118844460(MYL9)

PBRV:

138153557(MYL9)

OAA:	100073924(MYL9)

TACU:

119931660(MYL9)

GGA:	396215(MYL9)

PCOC:

116236856(MYL9)

MGP:	100549745(MYL9)

CJO:	107322805(MYL9)

TPAI:

128080912(MYL9)

LMUT:

125701342(MYL9)

NMEL:

110408206(MYL9)

APLA:

101799368(MYL9)

ACYG:

106045436(MYL9)

CATA:

118248803(MYL9)

AFUL:

116495666(MYL9)

TGU:	100230189(MYL9)

LSR:	110473783(MYL9)

SCAN:

103823660(MYL9)

PMOA:

120497731(MYL9)

OTC:	121332600(MYL9)

PRUF:

121365900(MYL9)

ATRC:

139604317(MYL9)

GFR:	102045323(MYL9)

FAB:	101818675(MYL9)

OMA:	130261380(MYL9)

PHI:	102114384(MYL9)

PMAJ:

107213424(MYL9)

CCAE:

111938346(MYL9)

CCW:	104698028(MYL9)

CBRC:

103624256(MYL9)

ACOE:

138121088(MYL9)

ETL:	114059723(MYL9)

ZAB:	102070862(MYL9)

ZLE:	135456348 135456367

ACHL:

103800827

SVG:	106859199(MYL9)

MMEA:

130579696(MYL9)

HRT:	120760134(MYL9)

SATI:

136368355(MYL9)

CCIC:

134051173(MYL9)

FPG:

101911603

FCH:	102048471(MYL9)

CCRI:

104161333

SHAB:

115615234(MYL9)

ACUN:

113490665(MYL9)

TALA:

104367727(MYL9)

ACHC:

115339909(MYL9)

HALD:

104313563

HLE:	104829963(MYL9)

AGEN:

126045318

HHAR:

128143683(MYL9)

GCL:

127023144

LDI:

104345337

MNB:

103773231

PPUS:

135188135(MYL9)

AVIT:

104274171(MYL9)

BRHI:

104489945

EGZ:	104125492(MYL9)

NNI:	104019952(MYL9)

PCRI:

104029563

PCAO:

104046518

PADL:

103921386(MYL9)

AFOR:

103902233(MYL9)

FGA:

104076692

GSTE:

104257431

CBOY:

140659361(MYL9)

CLV:	102095544(MYL9)

MUI:	104534675 104539429

PLET:

104617296(MYL9)

EHS:

104516832

CMAC:

104484091

CUCA:

104063213(MYL9)

TEO:

BREG:

OHA:

ACAR:

CPEA:

104390665(MYL9)

CVF:	104287607(MYL9)

RTD:	128916761(MYL9)

CRID:

134522469(MYL9)

AAM:	106499912(MYL9)

AROW:

112968470(MYL9)

NPD:	112945688(MYL9)

TGT:	104578088(MYL9)

DNE:	112983191(MYL9)

SCAM:

104146924(MYL9)

ASN:	102381896(MYL9)

AMJ:	102575766(MYL9)

CPOO:

109313257

GGN:	109294620(MYL9)

PSS:	102445169(MYL9)

CMY:	102934098(MYL9)

CCAY:

125622365(MYL9)

DCC:	119842077(MYL9)

CPIC:

101946943(MYL9)

TST:	117885774(MYL9)

CABI:

116818593(MYL9)

MRV:	120380916(MYL9)

ACS:	100567783(myl9)

ASAO:

132773228(MYL9)

PVT:	110083027(MYL9)

SUND:

121929887(MYL9)

PBI:	103055069(MYL9)

PMUR:

107288381(MYL9)

CTIG:

120299172(MYL9)

TSR:

106538627

PGUT:

117663663(MYL9)

APRI:

131194505(MYL9)

PTEX:

113434438(MYL9)

NSS:	113421339(MYL9)

VKO:	123031968(MYL9)

PMUA:

114599524(MYL9)

PRAF:

128416343(MYL9)

ZVI:	118088978(MYL9)

HCG:	128324068(MYL9)

GJA:	107112280(MYL9)

STOW:

125433639(MYL9)

EMC:	129329666(MYL9)

XLA:	446851(myl9.L) 447704(myl9.S)

XTR:	100124811(myl9)

NPR:	108787984(MYL9)

RTEM:

120918762(MYL9)

BBUF:

121003248(MYL9)

BGAR:

122941730(MYL9)

PWL:	138304035(MYL9)

MUO:	115475448(MYL9)

GSH:	117369246(MYL9)

DRE:	406493(myl9b) 450006(myl9a)

SRX:	107705895 107711796 107737046 107752860

SANH:

107653232 107666694 107690817 107692798

SGH:	107554878 107569439 107582309

CCAR:

109053403 109053407 109076564 109076571 122137619

CAUA:

113041320 113041388 113051007 113065835 113065838 113089331

CGIB:

127944925 127959852 128011069 128015286

PTET:

122332716(myl9a) 122346945(myl9b)

LROH:

127154432(myl9a) 127166623(myl9b)

OMC:	131532385(myl9a) 131541959(myl9b)

PPRM:

120463800(myl9a) 120467926(myl9b)

RKG:	130069850(myl9a) 130072973(myl9b)

MAMB:

125259918(myl9a) 125274076(myl9b)

CIDE:

127504795 127514242

CERY:

137008899(myl9a) 137010684(myl9b)

MASI:

127418827 127419637 127445918 127449272

TROS:

130544950(myl9a) 130556715(myl9b)

TDW:	130409331(myl9a) 130424426(myl9b)

MANU:

129430985(myl9a) 129450151(myl9b)

PDAB:

135750238(myl9a) 135783224(myl9b)

IPU:	100528638(myl9b) 108276062(myl9a)

IFU:	128614731(myl9b) 128619888(myl9a)

PHYP:

113529804 113530437

SMEO:

124384235(myl9b) 124398802(myl9a)

TFD:	113642920(myl9b) 113655192(myl9a)

TVC:	132844509(myl9b) 132862602(myl9a)

CGAR:

128510122(myl9a) 128526301(myl9b)

NGRA:

132885155(myl9b) 132896704(myl9a)

TRN:	134316866(myl9b) 134333980(myl9a)

AMEX:

103022187(myl9a) 103045271(myl9b)

CMAO:

118808383(myl9b) 118822297(myl9a)

EEE:	113569661 113582345

CHAR:

122130725(myl9b)

SPIL:

134092604(myl9b)

TRU:

101062217

TFS:	130524887(myl9b)

TNG:	GSTEN00034636G001

LCO:

104936390

NCC:

104959430

TBEN:

117486518(myl9b)

CGOB:

115007880

PGEO:

117446922(myl9b)

GACU:

117533412(myl9b)

EMAC:

134882805(myl9b)

ELY:	117257095(myl9b)

EFO:	125901176(myl9b)

PLEP:

121954133

SLUC:

116034107(myl9b)

ECRA:

117943234(myl9b)

ESP:

116688064

PFLV:

114553612

GAT:	120835574(myl9b)

PPUG:

119229437(myl9b)

AFB:	129105232(myl9b)

CLUM:

117731387

PSWI:

130208232(myl9b)

CANA:

137796112(myl9b)

CVE:	137879620(myl9b)

MSAM:

119886947(myl9b)

SCHU:

122868634(myl9b)

CUD:	121506922(myl9b)

SPUL:

138605563(myl9b)

LMIX:

132977499(myl9b)

ALAT:

119020927(myl9b)

ASTR:

137594996(myl9b)

MZE:

101473299

ONL:

100697131

OAU:	116326426(myl9b)

OLA:

101167032

OML:	112144837(myl9b)

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122833784(myl9b)

PPRL:

129358240(myl9b)

CVG:

107102948

GMU:	124856629(myl9b)

NFU:

107385525

KMR:	108239884(myl9b)

ALIM:

106518373

NWH:	119411690(myl9b)

AOCE:

111565883(myl9b)

EJA:	138203288(myl9b)

BFRE:

138628278(myl9b)

MCEP:

125006768(myl9b)

CSEM:

103386121

POV:

109629318

SSEN:

122768248(myl9b)

SSOE:

131460726(myl9b)

HHIP:

117762297(myl9b)

HSP:	118103350(myl9b)

PPLT:

128451270(myl9b)

SMAU:

118309319(myl9b)

LCF:	108884031(myl9b)

SDU:

111221962

SLAL:

111667752

XGL:	120783081(myl9b)

HCQ:

109522526

SSCV:

125976841(myl9b)

SBIA:

133507013(myl9b)

PEE:	133408871(myl9b)

PTAO:

133484050(myl9b)

BPEC:

110165714

ENY:	140372442(myl9b)

MALB:

109956204

BSPL:

114856293(myl9b)

SJO:	128356143(myl9b)

SSCO:

134003400(myl9b)

GMH:

115557136

SASA:

106565219(MLRN) 106583599(MLRN)

STRU:

115150175 115208297

OTW:	112214243 112246201

OMY:	110493970 110528481

OGO:	124002579 124027305

ONE:	115142782 115143463

OKI:	109891383 109891943

OKE:	118388998 118400561

OMM:	135539619 135541436

OCLA:

139370754 139413803

SALP:

111962334 111970447

SNH:	120064176 120065397

CCLU:

121551561 121575529

ELS:

105016743

OEP:	134010449(myl9b)

SFM:	108918459 108939421

PKI:

AANG:

AROT:

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:	102365825(MYL9)

CMK:	103171965(myl9)

RTP:

CPLA:

HOC:

LERI:

BFO:

BBEL:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

PFLL:

RZE:

ASTE:

PFUC:

DSV:	119458760 119458770

RSAN:

119379234 119379236

RMP:	119175816 119175817

TUT:

107360648

DPTE:

113790995 113791000 113794057 113795253

DFR:	124490068 124490641

CVS:

136986081

ABRU:

129958646 129975885

UDV:	129218023 129220211 129220212

SDM:

118204088

LPOL:

106460770 106460802 106464358 106468725

PMEO:

GAE:

HRF:

HASI:

HCRA:

CRG:

CANU:

CVN:

OSN:	115214760 115219731

NVE:	5495892 5516786 5516844

ATEN:

116293213 116293215 116302469

ADF:

107347202

AMIL:

114966450

MCAZ:

138030054 138044080 138044081 138060531

MFOO:

137970216 138006380 138008555 138012707

PDAM:

113670059

SPIS:

111320931 111336536

DGT:	114525748 114532508

XEN:	124441832 124452457

HSY:

130641011

RES:

135681728

VNX:	VNE69_05240

» show all

Reference

PMID:2526655

Authors

Kumar CC, Mohan SR, Zavodny PJ, Narula SK, Leibowitz PJ

Title

Characterization and differential expression of human vascular smooth muscle myosin light chain 2 isoform in nonmuscle cells.

Journal

Biochemistry 28:4027-35 (1989)
DOI:10.1021/bi00435a059

Sequence

[hsa:10398]

LinkDB

DBGET integrated database retrieval system