KEGG ORTHOLOGY: K13082

ORTHOLOGY: K13082

Entry

K13082                      KO

Symbol

DFR

Name

bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase [EC:1.1.1.219 1.1.1.234]

Pathway

map00941

Flavonoid biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00138

Flavonoid biosynthesis, naringenin => pelargonidin

Reaction

R03123

cis-3,4-leucopelargonidin:NADP+ 4-oxidoreductase

R03636

leucocyanidin:NADP+ 4-oxidoreductase

R04901

(2S)-flavan-4-ol:NADP+ 4-oxidoreductase

R05038

leucodelphinidin:NADP+ 4-oxidoreductase

R06610

(2S)-flavan-4-ol:NADP+ 4-oxidoreductase

R07998

5-deoxyleucopelargonidin:NADP+ 4-oxidoreductase

R07999

5-deoxyleucocyanidin:NADP+ 4-oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00941 Flavonoid biosynthesis
    K13082  DFR; bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.219  dihydroflavonol 4-reductase
     K13082  DFR; bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase
    1.1.1.234  flavanone 4-reductase
     K13082  DFR; bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase

Other DBs

GO:	0045552 0047890

Genes

ATH:	AT5G42800(DFR)

ALY:	9299065 9301555

CRB:

17877190

CSAT:

104725195 104760679 104771418

EUS:	EUTSA_v10003227mg

BRP:

103839279

BNA:	106403158 106447075

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10001757mg

PVY:

116119408

MINC:

123228680

TCC:	18591418 18610896

GRA:	105769058 105772697

GHI:	107905441 107935085 107938889 107957957

GAB:	108454128 108480324

HSYR:

120114676 120167561 120169034 120216676

DZI:	111312736 111315336 111315339

EGR:

104448776

GMX:	100778253 548087(DFR1) 732626(DFR2)

GSJ:	114384244 114391094 114392892

PVU:	PHAVU_001G012700g PHAVU_001G012800g PHAVU_007G246200g

VRA:	106763833 106764122 106770756 106770772 106771250

VAR:	108324448 108324922 108336257 108336367

VUN:	114191920 114193233 114193234 114193708

VUM:	124830594 124830645 124830655

CCAJ:

109811985 109811998

APRC:

113845972 113846034

MTR:	25482168 25482169

TPRA:

123886567 123886574

CAM:	101491984 101492767

PSAT:

127093431 127093432

VVO:	131596616 131596617 131596618

LJA:	Lj5g3v0108490.1(Lj5g3v0108490.1) Lj5g3v0108500.1(Lj5g3v0108500.1) Lj5g3v0108500.2(Lj5g3v0108500.2) Lj5g3v0108500.3(Lj5g3v0108500.3)

ADU:

107495990

AHF:	112697991 112697992 112756300 112756301

LANG:

109343177

PCIN:

129303088 129303142 129306003 129306209

QSA:	O6P43_016195

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103440468 103450464

MSYL:

126604732 126631239

PXB:	103928717 103954960

ZJU:	107420289 107420293

MNT:	21384592 21404779

CSAV:

115710150

RCU:

8288959

JCU:	105633822 105633823 105633824 110008657

HBR:	110638079 110638080 110638081 110655218 110655234

MESC:

110605890 110615791 110615792

POP:	7454367 7471942

PEU:	105113121 105128763

PALZ:

JRE:

CILL:

CAVE:

QSU:	111984642 111984643

QLO:	115974365 115974366

TWL:	119995119 120008961 120012083

VVI:	100233141(DFR) 100259090 100267635

VRI:	117905400 117906273 117906599

SLY:

544150

SPEN:

107010988

SOT:	102577487 102587107(DFR)

SSTN:

SDUL:

CANN:

LBB:

NTA:	107797232(Dfr2) 107803097(Dfr1)

NSY:

104212411

NTO:

104112288

NAU:	109208181 109232046

INI:	109177611(DFR-A) 109177619(DFR-B) 109177620(DFR-C)

ITR:	115997971 115999112 115999903

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

ECAD:

LSV:

CCAV:

DCR:	108216819 108220625 108222116 108222765 108222766 108224331 108224780

CSIN:

114263316 114299086 114299087 114306385

RVL:	131297914 131328276

AEW:	130758800 130783480 130784840

BVG:

104889670

SOE:

110794664

CQI:	110702165 110702205 110724547 110738821

ATRI:

130809783

MOF:	131163051 131163053

NNU:	104589331 104589332 104590621 104601829

MING:

122070773 122070775 122075392 122076687 122086119 122086459 122094122

TSS:	122660095 122661531 122662474 122666599 122666608

PSOM:

113333459 113345760

DOSA:

Os01t0633500-00(Os01g0633500)

OBR:

OGL:

BDI:

ATS:

TDC:	119268458 119276348

TAES:

100125685 123070190 123078633

TUA:

125544210

LPER:

127343060

LRD:	124666655 124666721

SBI:	8058202 8058203 8075972 8076097

ZMA:	100272982 100286107

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:	105033295 105048473

MUS:	103979760 103981125 103982813

ZOF:	121971619 122009647

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:	18422615 18422618 18422620

» show all

Reference

PMID:12667486

Authors

Fischer TC, Halbwirth H, Meisel B, Stich K, Forkmann G

Title

Molecular cloning, substrate specificity of the functionally expressed dihydroflavonol 4-reductases from Malus domestica and Pyrus communis cultivars and the consequences for flavonoid metabolism.

Journal

Arch Biochem Biophys 412:223-30 (2003)
DOI:10.1016/S0003-9861(03)00013-4

Sequence

[mdm:103450464]

LinkDB

DBGET integrated database retrieval system