KEGG   ORTHOLOGY: K13937
Entry
K13937                      KO                                     

Symbol
H6PD
Name
hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31]
Pathway
map00030  Pentose phosphate pathway
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01200  Carbon metabolism
Module
M00004  Pentose phosphate pathway (Pentose phosphate cycle)
M00006  Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
Disease
H01111  Cortisone reductase deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00030 Pentose phosphate pathway
    K13937  H6PD; hexose-6-phosphate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.47  glucose 1-dehydrogenase [NAD(P)+]
     K13937  H6PD; hexose-6-phosphate dehydrogenase
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.31  6-phosphogluconolactonase
     K13937  H6PD; hexose-6-phosphate dehydrogenase
Other DBs
RN: R02035 R02736
GO: 0047936 0017057
Genes
HSA: 9563(H6PD)
PTR: 100610187(H6PD)
PPS: 100993268(H6PD)
GGO: 101142424(H6PD)
PON: 100439160(H6PD)
NLE: 100588208(H6PD)
MCC: 710107(H6PD)
MCF: 102115057(H6PD)
CSAB: 103225643(H6PD)
CATY: 105580901(H6PD)
PANU: 100998776(H6PD)
RRO: 104663055(H6PD)
RBB: 108517948(H6PD)
TFN: 117093357(H6PD)
PTEH: 111544637(H6PD)
CJC: 100386191(H6PD)
SBQ: 101028058(H6PD)
MMUR: 105886073(H6PD)
MMU: 100198(H6pd)
MCAL: 110292201(H6pd)
MPAH: 110323039(H6pd)
RNO: 298655(H6pd)
MCOC: 116097046(H6pd)
MUN: 110565586(H6pd)
CGE: 100770090(H6pd)
PLEU: 114684027(H6pd)
NGI: 103733152(H6pd)
HGL: 101715539(H6pd)
CCAN: 109682341(H6pd)
OCU: 100357500(H6PD)
TUP: 102502621(H6PD)
CFA: 489642(H6PD)
VVP: 112924670(H6PD)
VLG: 121499630(H6PD)
AML: 100476557(H6PD)
UMR: 103666677(H6PD)
UAH: 113270543(H6PD)
ORO: 101384136(H6PD)
ELK: 111154817
MPUF: 101678627(H6PD)
EJU: 114213401
MLX: 118020035(H6PD)
FCA: 101098066(H6PD)
PYU: 121020455(H6PD)
PBG: 122479905(H6PD)
PTG: 102961280(H6PD)
PPAD: 109274062(H6PD)
AJU: 106984893(H6PD)
HHV: 120233658(H6PD)
BOM: 102267212(H6PD)
BIU: 109570359(SPSB1)
BBUB: 102403227(H6PD)
CHX: 102174863(H6PD)
OAS: 101114124(H6PD)
ODA: 120880179(H6PD)
CCAD: 122452568(H6PD)
SSC: 110261091(H6PD)
CFR: 102515995(H6PD)
CBAI: 105070998(H6PD)
CDK: 105106995(H6PD)
BACU: 103015524(H6PD)
LVE: 103083939(H6PD)
OOR: 101277991(H6PD)
DLE: 111187044(H6PD)
PCAD: 102979692(H6PD)
ECB: 100057646(H6PD)
EPZ: 103549083(H6PD)
EAI: 106826224(H6PD)
MYB: 102257733(H6PD)
MYD: 102767216(H6PD)
MMYO: 118676175(H6PD)
MNA: 107538438(H6PD)
HAI: 109381286(H6PD)
DRO: 112299077(H6PD)
SHON: 118986382(H6PD)
AJM: 119064079(H6PD)
MMF: 118626855(H6PD)
PALE: 102883153(H6PD)
PGIG: 120583122 120585684(H6PD)
RAY: 107520164(H6PD)
MJV: 108398242(H6PD)
TOD: 119235632(H6PD)
LAV: 100663707(H6PD)
TMU: 101347869
MDO: 100009940(H6PD)
SHR: 100924302(H6PD)
PCW: 110199547(H6PD)
OAA: 100082409(H6PD)
GGA: 428188(H6PD)
PCOC: 116242547(H6PD)
MGP: 100545189(H6PD)
CJO: 107323555(H6PD)
NMEL: 110408549(H6PD)
APLA: 101804195(H6PD)
ACYG: 106044323(H6PD)
TGU: 100228049(H6PD)
LSR: 110474401(H6PD)
SCAN: 103820784(H6PD)
PMOA: 120511102(H6PD)
OTC: 121344088(H6PD)
GFR: 102045426(H6PD)
FAB: 101813192(H6PD)
PHI: 102103089(H6PD)
PMAJ: 107213774(H6PD)
CCAE: 111938679(H6PD)
CCW: 104693331(H6PD)
ETL: 114056872(H6PD)
FPG: 101919545(H6PD)
FCH: 102049461(H6PD)
CLV: 102095298(H6PD)
EGZ: 104133127(H6PD)
NNI: 104008976(H6PD)
ACUN: 113487806(H6PD)
PADL: 103917966(H6PD)
AAM: 106499029(H6PD)
AROW: 112970092(H6PD)
NPD: 112957379(H6PD)
DNE: 112980546(H6PD)
ASN: 102369764(H6PD)
AMJ: 102562599(H6PD)
CPOO: 109314451(H6PD)
GGN: 109293705(H6PD)
PSS: 102461733(H6PD)
CMY: 102932628(H6PD)
CPIC: 101951423(H6PD)
TST: 117867793(H6PD)
CABI: 116821947(H6PD)
ACS: 100551772(h6pd)
PVT: 110073255(H6PD)
PBI: 103060486(H6PD)
PMUR: 107292353(H6PD)
TSR: 106547251(H6PD)
PGUT: 117678129(H6PD)
PMUA: 114602477(H6PD)
ZVI: 118087086(H6PD)
GJA: 107110280(H6PD)
XLA: 108696534(h6pd.L) 108697628(h6pd.S)
XTR: 100127695(h6pd)
NPR: 108787846(H6PD)
DRE: 569348(h6pd)
SGH: 107555977(h6pd)
CCAR: 109058644
IPU: 108271794(h6pd)
PHYP: 113534509(h6pd)
AMEX: 103045767(h6pd)
EEE: 113577968(h6pd)
TRU: 101073312(h6pd)
LCO: 104920493(h6pd)
NCC: 104956358(h6pd)
CGOB: 115008689(h6pd)
ELY: 117257356(h6pd)
PLEP: 121949736(h6pd)
SLUC: 116051263(h6pd)
ECRA: 117942968(h6pd)
PFLV: 114554348(h6pd)
GAT: 120834651(h6pd)
MSAM: 119886350(h6pd)
CUD: 121506743(h6pd)
MZE: 101464302(h6pd)
ONL: 100705236(h6pd)
OAU: 116334205(h6pd)
OLA: 101167199(h6pd)
OML: 112145329(h6pd)
XMA: 102223104(h6pd)
XCO: 114136110(h6pd)
XHE: 116711040(h6pd)
PRET: 103464522(h6pd)
CVG: 107089356(h6pd)
CTUL: 119775095(h6pd)
NFU: 107385214(h6pd)
KMR: 108231149(h6pd)
ALIM: 106516050(h6pd)
AOCE: 111584759(h6pd)
CSEM: 103385698(h6pd)
POV: 109638583(h6pd)
LCF: 108889991(h6pd)
SDU: 111222868(h6pd)
SLAL: 111648426 111651100(h6pd)
XGL: 120807414(h6pd)
HCQ: 109510667(h6pd)
BPEC: 110168637(h6pd)
MALB: 109959016(h6pd)
OMY: 110494665(h6pd) 110527799
SNH: 120058917(h6pd) 120065049
ELS: 105025428(h6pd)
SFM: 108933884(h6pd)
PKI: 111852979(h6pd)
AANG: 118211715(h6pd)
LOC: 102696021(h6pd)
PSPA: 121328817(h6pd) 121328964
LCM: 102349672(H6PD)
CMK: 103184186(h6pd)
RTP: 109934639(h6pd)
BFO: 118418047
BBEL: 109473865
SCLV: 120328471
SPU: 590387
APLC: 110983992
SKO: 100372939(H6PD)
PCAN: 112559208
BGT: 106060912
GAE: 121382121
CRG: 105340439
MYI: 110446859
PMAX: 117336150
OBI: 106867532
LAK: 106166073
NVE: 5520107
EPA: 110254168
ATEN: 116300417
ADF: 107345186
AMIL: 114954506
PDAM: 113666448
SPIS: 111328954
DGT: 114518006
AQU: 105314200
 » show all
Reference
  Authors
Clarke JL, Mason PJ
  Title
Murine hexose-6-phosphate dehydrogenase: a bifunctional enzyme with broad substrate specificity and 6-phosphogluconolactonase activity.
  Journal
Arch Biochem Biophys 415:229-34 (2003)
DOI:10.1016/S0003-9861(03)00229-7
Reference
  Authors
Mason PJ, Stevens D, Diez A, Knight SW, Scopes DA, Vulliamy TJ
  Title
Human hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) encoded at 1p36: coding sequence and expression.
  Journal
Blood Cells Mol Dis 25:30-7 (1999)
DOI:10.1006/bcmd.1999.0224
  Sequence
[hsa:9563]
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