Entry
Name
glucose 1-dehydrogenase [NAD(P)+];
D-glucose dehydrogenase (NAD(P)+);
hexose phosphate dehydrogenase;
beta-D-glucose:NAD(P)+ 1-oxidoreductase;
glucose 1-dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-glucose:NAD(P)+ 1-oxidoreductase
Reaction(IUBMB)
D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H + H+ [RN:
R01520 R01521 ]
Reaction(KEGG)
Substrate
Product
Comment
This enzyme has similar activity with either NAD+ or NADP+. cf. EC
1.1.1.118 , glucose 1-dehydrogenase (NAD+) and EC
1.1.1.119 , glucose 1-dehydrogenase (NADP+).
History
EC 1.1.1.47 created 1961, modified 2013
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K00034 glucose 1-dehydrogenase
K13937 hexose-6-phosphate dehydrogenase
K22969 glucose 1-dehydrogenase
Genes
MORG : 121441804 121448395
PGIG : 120583122 120585684(H6PD)
GAS : 123240955(H6PD) 123253917
XLA : 108696534(h6pd.L) 108697628(h6pd.S)
SANH : 107666990 107680711
CAUA : 113050323 113096461
CGIB : 127959241 128015869
SLAL : 111648426 111651100(h6pd)
SASA : 106565995 106582765
STRU : 115150953 115207473
OMY : 110494665(h6pd) 110527799
SALP : 111969778 111970174
SNH : 120058917(h6pd) 120065049
CCLU : 121574866(h6pd) 121578400
PSPA : 121328817(h6pd) 121328964
ARUT : 117425883 117432038
LPIC : 129263160 129263162
PVD : CFBP1590__3129(gdhB)
PPRC : PFLCHA0_c41590(ycdF)
PMUD : NCTC8068_01927(gdh)
PLUL : FOB45_05270 FOB45_21290
LCJ : NCTC11976_00901(ycdF)
NWR : E3U44_03330 E3U44_07185 E3U44_11030
BUI : AX768_27245 AX768_29670
CABA : SBC2_65210(gdhI_3) SBC2_80550(gdh_3)
AXY : AXYL_02533 AXYL_03471
AIS : BUW96_02910 BUW96_07240
ADY : HLG70_08720 HLG70_11190
PIG : EGT29_19320 EGT29_20780
MASW : AM586_07050 AM586_07425
MTIM : DIR46_06700 DIR46_15330
URU : DSM104443_03850(bacC)
UPL : DSM104440_03400(bacC_2)
NIY : FQ775_06260 FQ775_18840
NTU : NTH_00164(gdh_1) NTH_01083(gdh_2)
PMOB : HG718_01875 HG718_06135
RII : FFM53_023690 FFM53_025865
KAI : K32_07000 K32_39250(gdh)
BJU : BJ6T_22230 BJ6T_26020
BJP : RN69_10870 RN69_12685
BRS : S23_11440(gdh) S23_14710
BRC : BCCGELA001_09085 BCCGELA001_32155
BRAD : BF49_3830 BF49_4348 BF49_4849
BOT : CIT37_19200 CIT37_20640
BRQ : CIT40_25855 CIT40_27230
BGQ : X265_03385 X265_07285
BGZ : XH91_06700 XH91_08115
BSYM : CIT39_24920 CIT39_26210
BBET : F8237_20565 F8237_22685
BARH : WN72_06920 WN72_39055
BVZ : BRAD3257_6165(gdh) BRAD3257_8064(gdhII)
BDG : LPJ38_11870 LPJ38_13455
BBAN : J4G43_009410 J4G43_041920
BCAN : BcanWSM471_30035 BcanWSM471_31365
BCOU : IC761_05915 IC761_07770
BXN : I3J27_29625 I3J27_31885
BRAZ : LRP30_36100 LRP30_38540
BRAY : ML401_28040 ML401_29790
BOW : NWE53_28170 NWE53_29350
MOC : BB934_35295 BB934_38045
MLD : U0023_24470 U0023_26510 U0023_30215
DEQ : XM25_00225 XM25_05220
YTI : FNA67_04315 FNA67_08995
PSIN : CAK95_00895 CAK95_11090
NOH : G5V57_03535 G5V57_21080 G5V57_33115
AHT : ANTHELSMS3_04912 ANTHELSMS3_05110
LVS : LOKVESSMR4R_01373(gdhIV)
STAX : MC45_02805 MC45_12310
SPHA : D3Y57_00375 D3Y57_14900
SAER : NEF64_08815 NEF64_10830
KSC : CD178_01719(gdhIV_1)
SWF : E3E12_00260 E3E12_00265
SHUM : STHU_40150 STHU_50140
SMUC : JL100_000960 JL100_014265
DEX : HWD60_15440 HWD60_15485
DVN : HQ394_00785 HQ394_10145
AFE : Lferr_1535 Lferr_1879
AFJ : AFERRID_00840 AFERRID_29480
MSD : MYSTI_00045 MYSTI_06266
MYX : QEG98_00205 QEG98_34635
AVM : JQX13_13605 JQX13_46360
MBD : MEBOL_003445 MEBOL_004923
SCL : sce1528(gcd) sce6208(fabG11) sce7442
BSU : BSU02830(ycdF) BSU03930(gdh)
BSH : BSU6051_02830(ycdF) BSU6051_03930(gdh)
BSY : I653_01395 I653_02000
BSUT : BSUB_00332(ycdF) BSUB_00444(gdh)
BSUL : BSUA_00332(ycdF) BSUA_00444(gdh)
BSUS : Q433_01720 Q433_02335
BSO : BSNT_06602(ycdF) BSNT_06735(gdh)
BSN : BSn5_12995 BSn5_13570
BSQ : B657_02830(ycdF) B657_03930(gdh)
BSX : C663_0274(ycdF) C663_0386(gdh)
BSP : U712_01460 U712_02040
BSS : BSUW23_01450(ycdF) BSUW23_02030(gdh)
BIT : BIS30_11960 BIS30_12545
BLI : BL01382(gdh) BL01687(ycdF)
BLD : BLi00341(ycdF) BLi02566
BLH : BaLi_c03600(ycdF) BaLi_c26510(gdh)
BAY : RBAM_003090 RBAM_004180
BAQ : BACAU_0250(ycdF) BACAU_0354(gdh)
BYA : BANAU_0251(ycdF) BANAU_0354(gdh)
BAMP : B938_01295 B938_01860
BQY : MUS_0266(ycdF) MUS_0382(gdh)
BAML : BAM5036_0264(ycdF) BAM5036_0377(gdh)
BAMA : RBAU_0281(ycdF) RBAU_0391(gdh)
BAMN : BASU_0266(ycdF) BASU_0376(gdh)
BAMB : BAPNAU_0249(ycdF) BAPNAU_0359(gdh)
BAMT : AJ82_01700 AJ82_02305
BAMY : V529_02720(ycdF) V529_03790(gdh)
BMP : NG74_00288(ycdF) NG74_00395(gdh)
BAO : BAMF_0254(ycdF) BAMF_0361(gdh)
BAZ : BAMTA208_01290(ycdF) BAMTA208_01830(gdh)
BQL : LL3_00265(ycdF) LL3_00376(gdh)
BXH : BAXH7_00268(ycdF) BAXH7_00379(gdh)
BAMI : KSO_017595 KSO_018115
BAMC : U471_02680 U471_03840
BAMF : U722_01595 U722_02125
BSIA : CWD84_08895 CWD84_19935 CWD84_20455
BAE : BATR1942_20045 BATR1942_20675
BVM : B9C48_01570 B9C48_02105
BSON : S101395_02034 S101395_04702
BHT : DIC78_07995 DIC78_08590
BMOJ : HC660_03180(ycdF) HC660_04350(gdh)
BTEQ : G4P54_01625 G4P54_02155 G4P54_02825
BIQ : AN935_01455 AN935_02035
BSTR : QI003_01650(ycdF) QI003_02225(gdh)
BCZ : BCE33L4466(gdh) pE33L466_0368(gdh)
BTHR : YBT1520_24920 YBT1520_29954
BTHI : BTK_24775 BTK_29744
BBY : CY96_22740 CY96_29465
BPUM : BW16_01640 BW16_11530
BPUS : UP12_01615 UP12_10785
BGY : BGLY_0339 BGLY_2840(gdh)
BXI : BK049_06635 BK049_16305
BALT : CFN77_01640 CFN77_11380
BAER : BAE_09180 BAE_18530
BSAF : BSL056_01580 BSL056_11805
BCAB : EFK13_01810 EFK13_02410(gdh)
BRY : M0696_01635 M0696_02265(gdh)
BACW : QR42_01595 QR42_10735
BACP : SB24_07725 SB24_08260
BACB : OY17_04210 OY17_04740
BACY : QF06_00370 QF06_00935
BACL : BS34A_03380(ycdF) BS34A_04510(gdh)
BALM : BsLM_0295 BsLM_0414
BACS : AUL54_08760 AUL54_09270 AUL54_17805
BMQ : BMQ_0838(gdh) BMQ_1051 BMQ_3371
BMD : BMD_0838(gdh) BMD_1054 BMD_1796 BMD_3374
BMH : BMWSH_1813 BMWSH_4190 BMWSH_4406(gdh)
BMEG : BG04_285(gdhB) BG04_3132(gdhB) BG04_3338(gdhB)
PKS : IE339_13130 IE339_13345 IE339_22080
BGI : BGM20_16465 BGM20_17040
LYQ : MY533_07410(gdh) MY533_10280(gdh)
TAP : GZ22_00975 GZ22_04430
TAID : KS242_02150 KS242_05290
BMUR : ABE28_003035 ABE28_004715
PFRI : L8956_03490 L8956_04890
RMF : D5E69_11860 D5E69_16865 D5E69_18255
SARL : SAP2_00810 SAP2_07280
SPIC : SAMEA4384060_0787(gdh)
MACR : BHM04_00525 BHM04_09280
MBRU : MGG13_01070 MGG13_09140
MEPI : KFV12_01675 KFV12_10865
MEQU : KFV11_01120 KFV11_09270
MBOC : QSV55_01405 QSV55_09420
MCAK : MCCS_03100(gdhIV) MCCS_20860
MBOE : HT586_01630 HT586_10160
PJD : Pjdr2_0781 Pjdr2_4220 Pjdr2_4221
PMS : KNP414_01545 KNP414_02359
PMQ : PM3016_1853 PM3016_2623
POW : IJ21_12140 IJ21_13280
PPSC : EHS13_04905 EHS13_25810 EHS13_31545
PCHI : PC41400_15175 PC41400_25745
PRZ : GZH47_21975 GZH47_21980 GZH47_22620
PCEL : HUB94_12230 HUB94_12235
PHK : SK066_04730 SK066_19770
COHN : KCTCHS21_21540(fabG_1)
SACA : FFV09_07150 FFV09_12385
SURN : NCTC13766_00994(fabG_2)
LPG : BB562_02165 BB562_03460
LALI : LA20249_09160 LA20249_09170
EFU : HMPREF0351_11664(gdh)
CBOL : CGC65_04115 CGC65_12635
MAS : Mahau_2098 Mahau_2099
MYE : AB431_11095 AB431_25680
MTHN : 4412656_02890(fabG_14)
MGAD : MGAD_13450(gdh_1) MGAD_50740
MFLV : NCTC10271_03283(tdh_2)
NFR : ERS450000_00535(tdh_2) ERS450000_00733
NAD : NCTC11293_04007(tdh_2)
RRT : 4535765_02289(ycdF_3)
SVL : Strvi_2243 Strvi_3883
SRC : M271_06045 M271_14500
SMAL : SMALA_5860 SMALA_7201
SALW : CP975_19430 CP975_31690
SAUO : BV401_33190 BV401_39630
SSIA : A7J05_04495 A7J05_16595
SLK : SLUN_24090 SLUN_31455
FRP : AX769_13015 AX769_21270
PSFE : NG819_08105 NG819_08970
SATK : SA2016_2233 SA2016_3952
MICG : GJV80_00695 GJV80_05820 GJV80_14110
ACTQ : OG417_20780 OG417_24400
SACG : FDZ84_19875 FDZ84_30180
KUT : JJ691_101730 JJ691_80440(gdh)
ACTU : Actkin_02754(tdh_1)
STP : Strop_0391 Strop_0661
MICH : FJK98_10310 FJK98_29155
MCAB : HXZ27_11415 HXZ27_27890
MSAG : GCM10017556_18260(gdh) GCM10017556_45410(gdh)
VMA : VAB18032_01365 VAB18032_17610
MENO : Jiend_35350(gdh) Jiend_60490(ycdF)
MFEU : H1D33_03300 H1D33_17035
MCAY : PVK37_02825 PVK37_16930
MICF : QQG74_20430 QQG74_28405
ACTR : Asp14428_21470 Asp14428_73940(gdh)
PLAB : C6361_19630 C6361_26885
PLAT : C6W10_25045 C6W10_29235
PFLA : Pflav_077080(gdh_2)
RUB : GBA63_01770 GBA63_05500
CYN : Cyan7425_1811 Cyan7425_4436
LET : O77CONTIG1_02855(ycdF)
LBO : LBWT_19520 LBWT_28210 LBWT_56070
KOV : K9N68_16685 K9N68_35150 K9N68_38055
LSK : J5X98_00105 J5X98_07320
TOG : HNI00_00300 HNI00_01465
CYJ : Cyan7822_5687 Cyan7822_6114
GML : ISF26_01350 ISF26_02830 ISF26_10640
NPU : Npun_F1792 Npun_F2211 Npun_R3105
NOE : CLI64_15550 CLI64_18275 CLI64_23585
NED : HUN01_01015 HUN01_08535
NCW : NIES2107_14210 NIES2107_21430 NIES2107_41160
NCF : ANSO36C_54580 ANSO36C_57120(gdh)
HBQ : QI031_07990 QI031_11285
CALN : NIES2098_44790 NIES2098_46090 NIES2098_72020
RIV : Riv7116_2740 Riv7116_4408 Riv7116_5340
MDP : NIES3275_02490 NIES3275_13230 NIES3275_15590
TOQ : HCG51_01525 HCG51_07075 HCG51_27030
TTQ : NIES37_23730 NIES37_32730 NIES37_35880
ALAX : NIES50_50710 NIES50_53850 NIES50_62890
SCYT : SAMD_18970 SAMD_75980 SAMD_76520
SCYS : NIES4073_14850 NIES4073_77860
BSEN : DP114_01525 DP114_01540 DP114_17085
BOX : DP113_01515 DP113_01530 DP113_17020
NCN : BZZ01_00470 BZZ01_06760
CTHE : Chro_2174 Chro_3615 Chro_4252
STAN : STA3757_07280 STA3757_20600
KBB : ccbrp13_06640(gdh) ccbrp13_35000
DPD : Deipe_2470 Deipe_4345
OBG : Verru16b_02384(fabG_6)
MTAR : DF168_01564(fabG_13)
RBA : RB10002(gcd) RB7294(gdh)
PSL : Psta_2028 Psta_3187 Psta_3574
PIR : VN12_03790(ycdF) VN12_08675(yjmD) VN12_23100(gdhI)
RUL : UC8_20950(yjmD) UC8_23440(ycdF_3)
RML : FF011L_13840(adhT) FF011L_36370(ycdF_2)
ROL : CA51_32620(adhT) CA51_37280(fabG_6) CA51_50550(ycdF)
RUV : EC9_35040(adhT_2) EC9_46560(fabL) EC9_51160(ycdF)
RCF : Poly24_33490(adhT_1) Poly24_46590(ycdF_1) Poly24_50790(ycdF_2)
AHEL : Q31a_08780(fabG_1) Q31a_54820
LCRE : Pla8534_02520(gdhI_1) Pla8534_12880(ycdF_2) Pla8534_25860(yjjN_1) Pla8534_34130(fabG_6) Pla8534_53120(yjmD)
AAGG : ETAA8_05660(gdhI_1) ETAA8_14170 ETAA8_33190(gdhI_2) ETAA8_49190(adhT)
BVO : Pan97_00270(ycdF_1) Pan97_30250(adhA_2)
BREM : PSR63_10935 PSR63_23390
RLC : K227x_15970(gdhI) K227x_21340(yjmD)
SMAM : Mal15_10100(yjmD) Mal15_46870(ycdF_1)
SNEP : Enr13x_16530(ycdF) Enr13x_21900(kduD_1) Enr13x_62890(adhT)
LPAV : PLANPX_3336 PLANPX_5454
PEH : Spb1_05770(adhT) Spb1_21850(tdh_2) Spb1_39090(ycdF)
PBS : Plabr_0832 Plabr_1907 Plabr_3757
PLS : VT03_08360(ycdF) VT03_25955(yjmD)
FMR : Fuma_00966(yjmD) Fuma_03440 Fuma_03445 Fuma_04787(ycdF_2)
GMR : GmarT_19690(kduD) GmarT_56430(ycdF_2)
GAX : Pan161_57470(ycdF_2)
MRI : Mal4_30260(gdhI) Mal4_32540(adhT_2) Mal4_58550(ycdF)
SDYN : Mal52_20370(ycdF_2) Mal52_47450(gdhI) Mal52_48560(adhT) Mal52_56110(ycdF_4)
PLON : Pla110_10190(yjmD) Pla110_39690(ycdF_3)
ACAF : CA12_14990(ycdF) CA12_30690(gdhIV)
TPOL : Mal48_22960(adhT) Mal48_33100(gdhI)
CHYA : V22_00280(ycdF_1) V22_21940(gdhI_1)
CCOS : Pan44_00290 Pan44_33940(gdhI)
PVAR : SH412_000829 SH412_001217 SH412_002120
LRS : PX52LOC_01950 PX52LOC_06863
TSPH : KIH39_11495 KIH39_24935
SACI : Sinac_0374 Sinac_5723
PHM : PSMK_03410(gdh) PSMK_12480(gdh)
BHC : JFL75_01265 JFL75_18390
GRW : FTO74_12350 FTO74_13160
TALB : FTW19_18410 FTW19_21230
EDA : GWR55_07820 GWR55_11365
ADIN : H7849_17510 H7849_25645
TEMP : RBB75_00005 RBB75_15035
TPSC : RBB77_09625 RBB77_16845
PFER : IRI77_00125 IRI77_01345 IRI77_16115
ABAC : LuPra_04555(gno_6) LuPra_05149(tdh_3)
FGG : FSB75_06850 FSB75_10615 FSB75_13790
PEX : IZT61_16205 IZT61_21450
SMIZ : 4412673_01412(ycdF_2)
SDJ : NCTC13534_02163(cpnA_2)
MGIN : FRZ54_16200 FRZ54_17510
MGK : FSB76_09360 FSB76_30660
MDJ : LLH06_01260 LLH06_09945
SLI : Slin_1831 Slin_2303 Slin_2520
SMON : AWR27_04065 AWR27_04770 AWR27_07535
SPIK : EXU85_14595 EXU85_17025
SPIB : G8759_08765 G8759_23690 G8759_25595 G8759_33735
SFOL : H3H32_06825 H3H32_12690
SENF : GJR95_03490 GJR95_34290 GJR95_40755
EMZ : MB380_14120 MB380_17970
RSI : Runsl_2541 Runsl_4968 Runsl_5686
RUN : DR864_05770 DR864_13060 DR864_22380
FAE : FAES_2852(gdh1) FAES_4123(gdh3)
HYP : A0257_04570 A0257_20720
HAEI : MUN82_10865 MUN82_11615
PACT : CA264_02460 CA264_21150
CLIT : OQ292_05195 OQ292_24355
FBT : D770_00500 D770_09050 D770_22280
CHK : D4L85_07070 D4L85_18620
FMM : LVD15_14270 LVD15_20850
TPEL : P0M28_26370 P0M28_27455
CSAL : NBC122_02014(gdhIV)
CHRJ : CHRYMOREF3P_3733(gdhII)
PROC : Ptc2401_01897(ycdF)
MCHK : MchiMG62_23500(gdh)
HNO : LT974_02970 LT974_10405
HLU : LT972_05955 LT972_10525
HJE : HacjB3_03335 HacjB3_14020 HacjB3_14320
HALX : M0R89_07245 M0R89_12635 M0R89_20385
HAXZ : M0R88_07495 M0R88_13160
HAYC : NGM10_04480 NGM10_09445
HAXY : NGM07_12760 NGM07_16855 NGM07_22730 NGM07_23010 NGM07_23585
SALI : L593_00670 L593_11675
HARA : AArcS_0927(fabG5) AArcS_2091(fabG8) AArcS_2327(tdh4)
HMA : rrnAC0917(sorD) rrnAC2741(ywfD2)
HHI : HAH_1550(sorD) HAH_4332(gdh)
HHN : HISP_07915 HISP_16885
HAB : SG26_00695 SG26_15735
HALJ : G9465_11390 G9465_19940 G9465_19995
HLT : I7X12_19240 I7X12_19940
HAAD : MW046_00640 MW046_07360
HME : HFX_1090(gdh) HFX_5035(gdh)
HLS : KU306_03150 KU306_10095
HLM : DV707_10565 DV707_14875
HALM : FCF25_10560 FCF25_11780
HALP : DOS48_04160 DOS48_05560 DOS48_10025
HALB : EKH57_06810 EKH57_08775
HALQ : Hrr1229_000700 Hrr1229_000785
HSS : J7656_02185 J7656_11005
HSAI : HPS36_01355 HPS36_07575
SRUB : C2R22_00760 C2R22_15165
HALG : HUG10_02185 HUG10_06820
HALU : HUG12_08655 HUG12_14885
HDF : AArcSl_0251 AArcSl_2435(fabG5)
HSAL : JMJ58_15915 JMJ58_23030
HXA : Halxa_0458 Halxa_4120
NPL : FGF80_03060 FGF80_09115
HJT : DVR14_17705 DVR14_21835
HLO : J0X27_02975 J0X27_09030
SAWL : NGM29_03715 NGM29_13845 NGM29_18665
HALV : NGM15_05125 NGM15_13305 NGM15_15715
HLR : HALLA_06630 HALLA_07495
HLC : CHINAEXTREME10120 CHINAEXTREME17795
NARA : QQ977_07165 QQ977_12070
NBG : DV706_11030 DV706_17330
NAS : GCU68_01075 GCU68_20045
VSO : Vsou_26120(gdh) Vsou_26330
NFN : NFRAN_2573 NFRAN_2950
» show all
Taxonomy
Reference
Authors
Banauch D, Brummer W, Ebeling W, Metz H, Rindfrey H, Lang H, Leybold K, Rick W, Staudinger HJ.
Title
[A glucose dehydrogenase for the determination of glucose concentrations in body fluids (author's transl)]
Journal
Z Klin Chem Klin Biochem 13:101-7 (1975)
Reference
2
Authors
Brink NG.
Title
Beef liver glucose dehydrogenase. 1. Purification and properties.
Journal
Acta Chem Scand 7:1081-1089 (1953)
Reference
Authors
Pauly HE, Pfleiderer G
Title
D-glucose dehydrogenase from Bacillus megaterium M 1286: purification, properties and structure.
Journal
Reference
Authors
STRECKER HJ, KORKES S.
Title
Glucose dehydrogenase.
Journal
J Biol Chem 196:769-84 (1952)
Reference
Authors
Thompson RE, Carper WR.
Title
Glucose dehydrogenase from pig liver. I. Isolation and purification.
Journal
Reference
Authors
Fujita Y, Ramaley R, Freese E
Title
Location and properties of glucose dehydrogenase in sporulating cells and spores of Bacillus subtilis.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.47
ExPASy - ENZYME nomenclature database: 1.1.1.47
LinkDB
All DBs