KEGG ORTHOLOGY: K14463

ORTHOLOGY: K14463

Entry

K14463                      KO

Symbol

MTTP, MTP

Name

microsomal triglyceride transfer protein large subunit

Pathway

map04975

Fat digestion and absorption

Disease

H00160

Abetalipoproteinemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K14463  MTTP, MTP; microsomal triglyceride transfer protein large subunit

Other DBs

GO:

0005319

Genes

HSA:	4547(MTTP)

PTR:	471397(MTTP)

PPS:	100973271(MTTP)

GGO:	101139172(MTTP)

PON:	100454883(MTTP)

PPYG:

129035193(MTTP)

NLE:	100588559(MTTP)

HMH:	116474868(MTTP)

SSYN:

129491693(MTTP)

MCC:	708832(MTTP)

MCF:	102128179(MTTP)

MTHB:

126955212

MNI:	105486366(MTTP)

CSAB:

103236027(MTTP)

CATY:

105571356(MTTP)

PANU:

101019974(MTTP)

TGE:	112624750(MTTP)

MLEU:

105531440(MTTP)

RRO:	104668844(MTTP)

RBB:	108515435(MTTP)

TFN:	117064086(MTTP)

PTEH:

111547958(MTTP)

CANG:

105512662(MTTP)

CJC:	100389249(MTTP)

SBQ:	101038858(MTTP)

CIMI:

108291182

CSYR:

103254321(MTTP)

MMUR:

105856569(MTTP)

LCAT:

123627357

PCOQ:

105807648(MTTP)

OGA:	100958632(MTTP)

MMU:	17777(Mttp)

MCAL:

110290714(Mttp)

MPAH:

110320372(Mttp)

RNO:	310900(Mttp)

MCOC:

116094348(Mttp)

ANU:	117707255(Mttp)

ASYL:

127682503(Mttp)

MUN:	110560065(Mttp)

CGE:	100759278(Mttp)

MAUA:

101836921(Mttp)

PROB:

127222960(Mttp) 127223142

PLEU:

MORG:

MFOT:

AAMP:

NGI:	103728045(Mttp)

HGL:	101702738(Mttp)

CPOC:

100734244(Mttp)

CCAN:

109697422(Mttp)

DORD:

105991182(Mttp)

DSP:

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

TUP:	102482251(MTTP)

GVR:	103602748(MTTP)

CFA:	487873(MTTP)

CLUD:

112644796

VVP:	112932671(MTTP)

VLG:

121493255

NPO:	129521122(MTTP)

AML:	100479021(MTTP)

UMR:

103677927

UAH:	113263115(MTTP)

UAR:

123788813

ELK:

111155888

LLV:

125093208

MPUF:

101687395(MTTP)

MNP:	132001638(MTTP)

MLK:	131829994(MTTP)

NVS:

122889353

ORO:	101367582(MTTP)

EJU:	114201321(MTTP)

ZCA:

113924669

MLX:	118026990(MTTP)

NSU:

110572140

LWW:	102735714(MTTP)

FCA:	101087920(MTTP)

PYU:

121032024

PCOO:

112858132(MTTP)

PBG:

122478227

PVIV:

125163671(MTTP)

LRUF:

124520611

LGF:

123594956

AJU:

106972165

PTG:	102968367(MTTP)

PPAD:

109247228(MTTP)

PUC:

125922953

PLEZ:

122218018

HHV:

120220779

BTA:	280868(MTTP)

BOM:	102267950(MTTP)

BIU:	109560313(MTTP)

BBUB:

102410404

BBIS:

104994655(MTTP)

CHX:	102179649(MTTP)

OAS:	101110939(MTTP)

BTAX:

128049892(MTTP)

CSUM:

138081714(MTTP)

ODA:

120861897

CCAD:

122422362

MREE:

136147937(MTTP)

OVR:	110131530(MTTP)

MBEZ:

129561806(MTTP)

SSC:	397381(MTTP)

CFR:	102517510(MTTP)

CBAI:

105067898(MTTP)

CDK:	105089547(MTTP)

VPC:	102527760(MTTP)

BACU:

103015727(MTTP)

BMUS:

118895527

LVE:	103088209(MTTP)

OOR:	101276559(MTTP)

LALB:

132519189(MTTP)

DLE:	111179099(MTTP)

PCAD:

102995758(MTTP)

PSIU:

116754801(MTTP)

PPHC:

136123540(MTTP)

NASI:

112393763(MTTP)

ECB:	100053803(MTTP)

EPZ:	103562974(MTTP)

EAI:

106834446

MYB:	102242297(MTTP)

MYD:	102774612(MTTP)

MMYO:

118671732

MLF:	102426844(MTTP)

MDT:	132215863(MTTP)

MYUM:

138993144(MTTP)

PKL:

118703632

EFUS:

103299798(MTTP)

MNA:	107545528(MTTP)

DRO:	112317804(MTTP)

SHON:

118979955

AJM:	119054088(MTTP)

PDIC:

114492614

PHAS:

123806823

MMF:

118641910

PPAM:

129085330(MTTP)

HAI:	109392926(MTTP)

RFQ:	117021984(MTTP)

PALE:

102877850(MTTP)

PGIG:

120591126

PVP:	105293041(MTTP)

RAY:

107517921

MJV:

108410054

TOD:	119243693(MTTP)

SARA:

101554955(MTTP)

SFUM:

130023598(MTTP)

SETR:

126025472(MTTP)

LAV:	100659913(MTTP)

TMU:

101350572

ETF:

101659831

DNM:	101425075(MTTP)

MDO:	100015583(MTTP)

GAS:

123251498

SHR:	100919971(MTTP)

AFZ:

127542046

PCW:	110209672(MTTP)

TVP:

118852989

PBRV:

138165794(MTTP)

OAA:

100086103

TACU:

119947697

GGA:	422709(MTTP) 769580(MTTPL)

PCOC:

116235037 116238897(MTTP)

MGP:	100545321(MTTP) 100545586

CJO:	107313645(MTTP) 107315756

TPAI:

128077798 128080030(MTTP)

LMUT:

125691706 125693478

NMEL:

110397275(MTTP) 110400014

APLA:

101789684 101805352

ACYG:

106030713 106048110(MTTP)

CATA:

118243696(MTTP) 118246816

AFUL:

116489028(MTTP) 116491262

TGU:	100232193(MTTP) 105759397

LSR:	110477787 110481574(MTTP)

SCAN:

103823743 103826030(MTTP)

PMOA:

120501053 120502823

OTC:	121336135 121346572

PRUF:

121353888 121362604

ATRC:

139592605(MTTP) 139595291

GFR:	102037649(MTTP) 102040639

FAB:	101810741 101821654(MTTP)

OMA:	130252047(MTTP) 130255182

PHI:	102105042(MTTP) 102114701

PMAJ:

107203562(MTTP) 107206519

CCAE:

111929438(MTTP) 111931472

CCW:	104695064 104697086

CBRC:

103617245 103617375(MTTP)

ACOE:

138109537(MTTP) 138112786

ETL:	114062707(MTTP) 114071321

ZAB:	102072648(MTTP) 102074858

ZLE:	135447340(MTTP) 135449872

ACHL:

103807053 103808810(MTTP)

SVG:	106852556(MTTP) 106856731

MMEA:

130585287 130585693(MTTP)

HRT:	120752854(MTTP) 120756098

SATI:

136360555(MTTP) 136364579

CCIC:

134044560(MTTP) 134046297

FPG:	101910465 101914987(MTTP)

FCH:	102053425(MTTP) 102055751

CCRI:

104167298 104168863(MTTP)

NNT:	104405404(MTTP) 104410819

SHAB:

115608593 115610833(MTTP)

ACUN:

113479632(MTTP) 113481949

TALA:

104362425 104366834

ACHC:

115345899 115348626

HALD:

104315272 104322388(MTTP)

HLE:	104839625 104843316(MTTP)

AGEN:

126043104 126044767

HHAR:

128136351(MTTP) 128147520

GCL:	127016066 127018088

CSTI:

104552116 104558878(MTTP)

LDI:	104342714 104346898(MTTP)

MNB:	103773133 103779516(MTTP)

DPUB:

104305245(MTTP) 104308866

PPUS:

135176519 135177973(MTTP)

AVIT:

104270147 104276988(MTTP)

BRHI:

104489966(MTTP)

EGZ:	104122612 104128419

NNI:	104013553 104021187(MTTP)

PCRI:

104031382(MTTP) 104035818

PCAO:

104050642(MTTP)

PADL:

103918597 103919514(MTTP)

AFOR:

103894212(MTTP) 103908243

FGA:	104070229(MTTP) 104075298

GSTE:

104253611(MTTP) 104260736

CBOY:

140651793(MTTP) 140655952

CLV:	102092545 102097314(MTTP)

CNIC:

135988249(MTTP) 135991136

MUI:	104534157(MTTP) 104540025

PGUU:

104458428(MTTP) 104472388

PLET:

104618838 104618966(MTTP)

EHS:	104503406(MTTP) 104509794

CMAC:

104477599 104482755(MTTP)

CUCA:

104054905 104057214(MTTP)

TEO:	104374901 104379651(MTTP)

BREG:

104629967(MTTP) 104633396

OHA:	104329802 104331646(MTTP)

ACAR:

104521243(MTTP) 104532759

CPEA:

104389248 104393655(MTTP)

CVF:	104286867(MTTP) 104291677

RTD:	128909848(MTTP) 128911652

CRID:

134516640(MTTP) 134517465

AAM:	106482554 106492137(MTTP)

AROW:

112968635 112972220(MTTP)

NPD:	112952218 112957291(MTTP)

TGT:	104572254(MTTP)

DNE:	112985892 112988493(MTTP)

SCAM:

104144510 104153434(MTTP)

ASN:	102382111 102382727(MTTP)

AMJ:	102560686(MTTP) 102567068

CPOO:

109312557 109322313(MTTP)

GGN:	109290967 109304052(MTTP)

PSS:	102444059 102461756(MTTP)

CMY:	102936629 102947459

CCAY:

125635217 125640317

DCC:	119854753 119858854

CPIC:

101946433 101952774

TST:	117878101(MTTP) 117880660

CABI:

116815028(MTTP) 116826179

MRV:	120369222 120405526

ACS:	100552347(mttp) 100565626

ASAO:

132771165 132776973(MTTP)

PVT:	110073674 110091495(MTTP)

SUND:

121924792 121931155

PBI:	103049947 103067726(MTTP)

PMUR:

107288768(MTTP) 107292170

CTIG:

120310110 120316103

TSR:	106538954 106555501(MTTP)

PGUT:

117670675 117679876(MTTP)

APRI:

131201395 131203068(MTTP)

PTEX:

113434831(MTTP) 113444686

NSS:	113415332(MTTP) 113421038

VKO:	123018253 123023170

PMUA:

114597233 114604349(MTTP)

PRAF:

128413951(TBATA) 128421328(MTTP)

ZVI:	118083718(MTTP) 118096639(TBATA)

HCG:	128326661(MTTP) 128349559(TBATA)

GJA:	107114485(MTTP) 107120526

STOW:

125437420 125440140

EMC:	129332916 129336606(MTTP)

XLA:	100381009(mttp.2.S) 108695783 108706738(mttp.1.S) 108710823(mttp.1.L)

XTR:	100127803(mttp.2) 100487453(mttp.1)

NPR:	108793364(MTTP) 108803095

RTEM:

120910433 120932843

ACAT:

141106176 141110198(MTTP)

BBUF:

120989835 121003681

BGAR:

122924568 122945269

DTC:	141088709 141100890(MTTP)

PWL:	138290316(MTTP) 138300801

MUO:	115461136(MTTP) 115470349

GSH:	117359446 117366086(MTTP)

DRE:	406207(mttp)

SRX:	107723195 107758845

SANH:

107665974 107692610

SGH:	107557955 107564103

CCAR:

CAUA:

CGIB:

PTET:

LROH:

127181296(mttp)

GRF:	141336466(mttp)

OMC:	131548478(mttp)

PPRM:

120478289

RKG:	130097646(mttp)

MAMB:

125272468

CIDE:

127519104

CERY:

137032053(mttp)

MASI:

127444228 127445013

TROS:

130552538(mttp)

TDW:	130412865(mttp)

MANU:

129444866(mttp)

PDAB:

135735815(mttp)

IPU:	108260851(mttp) 108263461

IFU:	128604270(mttp) 128605648

PHYP:

113525062(mttp) 113544337

SMEO:

124381111 124396139

TFD:	113635353 113639813

TVC:	132842015(mttp) 132847327

CGAR:

128508648(mttp) 128529243

NGRA:

132882780(mttp) 132888673

TRN:	134315287 134326669(mttp)

AMEX:

103026313 103028418

CMAO:

118810438 118816963

EEE:	113580964 113583531(mttp)

CHAR:

105906997

SPIL:

134068142(mttp)

TRU:	101064126(mttp)

TFS:	130527128(mttp)

TNG:	GSTEN00023255G001

LCO:	104930185(mttp)

NCC:	104950294(mttp)

TBEN:

117481939(mttp)

CGOB:

115013179(mttp)

PGEO:

117447196(mttp)

GACU:

117538019(mttp)

EMAC:

134865285(mttp)

ELY:	117255635(mttp)

EFO:

125886080

PLEP:

121942664

SLUC:

116034305

ECRA:

117955262(mttp)

ESP:	116699002(mttp)

PFLV:

114568817(mttp)

GAT:

120825798

PPUG:

119218227(mttp)

AFB:	129095487(mttp)

CLUM:

117732091(mttp)

PSWI:

130189810(mttp)

CANA:

137793083(mttp)

CVE:	137885193(mttp)

MSAM:

119898986

SCHU:

122872988

CUD:

121507936

SPUL:

138594839(mttp)

LMIX:

132990671(mttp)

ALAT:

119028922

ASTR:

137600462(mttp)

MZE:	101488100(mttp)

ONL:	100692375(mttp)

OAU:

116334484

OLA:	101169409(mttp)

OML:

112157386

CSAI:

133458874(mttp)

XMA:	102231439(mttp)

XCO:	114145571(mttp)

XHE:	116720783(mttp)

PRET:

103466043(mttp)

PFOR:

103137837(mttp)

PLAI:

106948259(mttp)

PMEI:

106919289(mttp)

GAF:

122829411

PPRL:

129367230(mttp)

CVG:	107097687(mttp)

CTUL:

119774733

GMU:

124868553

NFU:	107375258(mttp)

KMR:

108231547

ALIM:

106517167(mttp)

NWH:

119407494

AOCE:

111575319(mttp)

EJA:	138209606(mttp)

BFRE:

138630846(mttp)

MCEP:

125004706

CSEM:

103383652(mttp)

POV:	109637857(mttp)

SSEN:

122771331

SSOE:

131466515(mttp)

HHIP:

117762126(mttp)

HSP:

118098027

PPLT:

128437247(mttp)

SMAU:

118312709

LCF:

108896498

SDU:	111231471(mttp)

SLAL:

111664033(mttp)

XGL:

120800945

HCQ:	109519899(mttp)

SSCV:

125968469(mttp)

SBIA:

133505563(mttp)

PEE:	133404218(mttp)

PTAO:

133477500(mttp)

BPEC:

110165382(mttp)

ENY:	140377413(mttp)

MALB:

109961396(mttp)

BSPL:

114854294(mttp)

SJO:	128369280(mttp)

SSCO:

133991999(mttp)

GMH:	115540704(mttp)

SASA:

106602715 106609996

STRU:

115192079 115202047

OTW:	112231657 112261435

OMY:	110497503 110534276

OGO:	124001366 124012162

ONE:	115137216 115145817

OKI:	109894203 109901026

OKE:	118362906 118395306

OMM:	135506648 135507820

OCLA:

139374922 139418765

SALP:

111971518 112068700 112072532

SNH:	120034950 120052757

CCLU:

121572297

ELS:	105030943(mttp)

OEP:	134033788(mttp)

SFM:	108925691(mttp)

PKI:	111853057(mttp)

AANG:

118226930(mttp)

AROT:

135255884(mttp)

CCOG:

133130135(mttp)

LOC:	102697087(mttp) 107077292

PSPA:

121295664 121322428 121325337

ARUT:

117409678 117418621 117421220

PSEX:

120533105

LCM:	102350159 102361928(MTTP)

CMK:	103185869 103188745

RTP:	109922915 109926398

CPLA:

122539515 122541791

HOC:	132833298(mttp) 132834934

LERI:

129700573(mttp) 129713005

HAKA:

140714240 140726266(mttp)

PMRN:

116940336 116951057

LRJ:	133350542 133354341

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

SKO:

PFLL:

DME:	Dmel_CG9342(Mtp)

DER:

6548807

DSI:	Dsimw501_GD21667(Dsim_GD21667)

DYA:	Dyak_GE13015

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17847

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135950221(Mtp) 135955460

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:	5572425 5573098

AALB:

109415691 109416526

ASUA:

134212807

CQU:	CpipJ_CPIJ003835

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

139106276(Mtp)

TLN:	139820137(Mtp)

HST:

DQU:

CFO:

FEX:

PMEC:

138939559(Mtp)

LHU:	105671891(Mtp)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:	124215344(Mtp)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138138204(Mtp)

DPA:

109536737

ESIM:

136417762(Mtp)

EFOR:

136338966(Mtp)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

MSEX:

DPL:	KGM_213188

MJU:

NIQ:

VCD:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

TNL:

OFU:

ATRA:

GMW:

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106680197(Mtp)

NLU:

111061585

HVI:

124362755

MQU:

128990784

PHU:	Phum_PHUM189990

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138716484(Mtp)

BROR:

134543341

IEL:

124171032

HAMR:

139691259(Mtp)

FCD:

110852351

DPX:	DAPPUDRAFT_220651

DMK:

116924426

DPZ:

124320765

AFRA:

136036322 136036570

PVM:	113825000(Mtp)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123752524(Mtp)

CQD:	128693241(Mtp)

PTRU:

123520541

ESN:

126998459

MNZ:

135225178

MRJ:	136856637(Mtp)

PORN:

139757632(Mtp)

HAZT:

108675837

EAF:

111696353

LSM:	121129882(Mtp)

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136973445 136984995

ABRU:

129963564 129972494

UDV:

129221625

SDM:	118181823 118194056

PMEO:

129597356

CEL:	CELE_K02D7.4(dsc-4)

CBR:	CBG_13520(Cbr-dsc-4)

CRQ:	GCK72_016317

NAI:	NECAME_03573

HRO:	HELRODRAFT_159026

LGI:	LOTGIDRAFT_229701

PVUL:

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LSAX:

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HRJ:

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OED:

MYI:

PMAX:

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OBI:

OSN:

LJP:

LAK:	106160427 106172446

LLON:

135494184

» show all

Reference

PMID:8361539

Authors

Sharp D, Blinderman L, Combs KA, Kienzle B, Ricci B, Wager-Smith K, Gil CM, Turck CW, Bouma ME, Rader DJ, et al.

Title

Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia.

Journal

Nature 365:65-9 (1993)
DOI:10.1038/365065a0

Sequence

[hsa:4547]

Reference

PMID:12518019

Authors

Hussain MM, Shi J, Dreizen P

Title

Microsomal triglyceride transfer protein and its role in apoB-lipoprotein assembly.

Journal

J Lipid Res 44:22-32 (2003)
DOI:10.1194/jlr.R200014-JLR200

LinkDB

DBGET integrated database retrieval system