KEGG ORTHOLOGY: K15348

ORTHOLOGY: K15348

Entry

K15348                      KO

Symbol

PLEKHM2, SKIP

Name

pleckstrin homology domain-containing family M member 2

Pathway

map05132

Salmonella infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K15348  PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K15348  PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2
Membrane trafficking [BR:ko04131]
Endosome - Lysosome transport
  Arf GTPases and associated proteins
   Other Arf associated proteins
    K15348  PLEKHM2, SKIP; pleckstrin homology domain-containing family M member 2

Other DBs

GO:

0019894

Genes

HSA:	23207(PLEKHM2)

PTR:	456462(PLEKHM2)

PPS:	100990535(PLEKHM2)

GGO:	101138738(PLEKHM2)

PON:	100461194(PLEKHM2)

PPYG:

129006908(PLEKHM2)

NLE:	100592522(PLEKHM2)

HMH:	116812963(PLEKHM2)

SSYN:

129472504(PLEKHM2)

MCC:	701382(PLEKHM2)

MCF:	102123992(PLEKHM2)

MTHB:

126953894

MNI:	105473252(PLEKHM2)

CSAB:

103225546(PLEKHM2)

CATY:

105599426(PLEKHM2)

PANU:

101013258(PLEKHM2)

TGE:	112622022(PLEKHM2)

MLEU:

105549429(PLEKHM2)

RRO:	104677701(PLEKHM2)

RBB:	108524257(PLEKHM2)

TFN:	117093247(PLEKHM2)

PTEH:

111527278(PLEKHM2)

CANG:

105510233(PLEKHM2)

CJC:	100410470(PLEKHM2)

SBQ:	101045809(PLEKHM2)

CIMI:

108286925(PLEKHM2)

ANAN:

105708376(PLEKHM2)

CSYR:

103260479(PLEKHM2)

MMUR:

105870445(PLEKHM2)

LCAT:

123635952(PLEKHM2)

ERUF:

138390467(PLEKHM2)

PCOQ:

105824974(PLEKHM2)

OGA:	100957281(PLEKHM2)

MMU:	69582(Plekhm2)

MCAL:

110292180(Plekhm2)

MPAH:

110322875(Plekhm2)

RNO:	313667(Plekhm2)

MCOC:

116096964(Plekhm2)

ANU:	117708542(Plekhm2)

ASYL:

127681570(Plekhm2)

MUN:	110545018(Plekhm2)

CGE:	100770785(Plekhm2)

MAUA:

101843161(Plekhm2)

PROB:

127213373(Plekhm2)

PLEU:

114700864(Plekhm2)

PMAV:

102921827(Plekhm2)

MORG:

121448428(Plekhm2)

MFOT:

126508316

AAMP:

119816833(Plekhm2)

CNL:	130883807(Plekhm2)

NGI:	103725344(Plekhm2)

HGL:	101707360(Plekhm2)

CPOC:

100732114(Plekhm2)

CCAN:

109692564(Plekhm2)

DORD:

105990004(Plekhm2)

DSP:	122099146(Plekhm2)

DMER:

138814819 138838409(Plekhm2)

PLOP:

125354607(Plekhm2)

NCAR:

124987281

MMMA:

107142210(Plekhm2)

ITI:	101969256(Plekhm2)

OCU:

100348790

OPI:	101531990(PLEKHM2)

OCZ:	121161522(PLEKHM2)

TUP:	102470096(PLEKHM2)

GVR:	103590587(PLEKHM2)

CFA:	100687846(PLEKHM2)

CLUD:

112660621(PLEKHM2)

VVP:	112929701(PLEKHM2)

VLG:	121497393(PLEKHM2)

NPO:	129514262(PLEKHM2)

AML:	100482759(PLEKHM2)

UMR:	103666843(PLEKHM2)

UAH:	113270664(PLEKHM2)

UAR:	123777784(PLEKHM2)

ELK:

111154594

LLV:

125097653

MPUF:

101678512(PLEKHM2)

MNP:	132001573(PLEKHM2)

MLK:	131808854(PLEKHM2)

NVS:	122899484(PLEKHM2)

ORO:	101369399(PLEKHM2)

EJU:	114213185(PLEKHM2)

ZCA:	113932743(PLEKHM2)

MLX:	118019971(PLEKHM2)

MANO:

123860040(PLEKHM2)

NSU:	110575365(PLEKHM2)

LWW:	102729604(PLEKHM2)

FCA:	101084211(PLEKHM2)

PYU:	121021608(PLEKHM2)

PCOO:

112861797(PLEKHM2)

PBG:	122479968(PLEKHM2)

PVIV:

125172700(PLEKHM2)

LRUF:

124514902

LGF:	123597233(PLEKHM2)

AJU:

106975576

PTG:	102964529(PLEKHM2)

PPAD:

109273880(PLEKHM2)

PUC:

125913732

PLEZ:

122226898(PLEKHM2)

HHV:	120229774(PLEKHM2)

CCRU:

144241131(PLEKHM2)

BTA:	515552(PLEKHM2)

BOM:	102268391(PLEKHM2)

BIU:	109570388(PLEKHM2)

BJV: 133227978(PLEKHM2)

BBUB:

102414752(PLEKHM2)

BKE:	129653186(PLEKHM2)

BBIS:

104996110(PLEKHM2)

CHX:	102170806(PLEKHM2)

OAS:	101109632(PLEKHM2)

BTAX:

128061205(PLEKHM2)

CSUM:

138090362(PLEKHM2)

ODA:	120880586(PLEKHM2)

CCAD:

122451903(PLEKHM2)

MREE:

136168496(PLEKHM2)

OVR:	110124923(PLEKHM2)

MBEZ:

129551384(PLEKHM2)

SSC:	100522681(PLEKHM2)

CFR:	102520772(PLEKHM2)

CBAI:

105070940(PLEKHM2)

CDK:	105107061(PLEKHM2)

VPC:	102538008(PLEKHM2)

BACU:

103003848(PLEKHM2)

BMUS:

118895486(PLEKHM2)

LVE:	103085258(PLEKHM2)

OOR:	101273116(PLEKHM2)

LALB:

132515200(PLEKHM2)

GMF:	115864137(PLEKHM2)

DDP:	132427451(PLEKHM2)

DLE:	111187092(PLEKHM2)

PCAD:

102991090(PLEKHM2)

PSIU:

116759319(PLEKHM2)

PPHC:

136129206(PLEKHM2)

NASI:

112402718(PLEKHM2)

ECB:	100054085(PLEKHM2)

EPZ:	103552941(PLEKHM2)

EAI:	106828001(PLEKHM2)

MYB:	102255482(PLEKHM2)

MYD:	102758666(PLEKHM2)

MMYO:

118675424(PLEKHM2)

MLF:	102430692(PLEKHM2)

MDT:	132231647(PLEKHM2)

MYUM:

139002906(PLEKHM2)

PKL:	118723540(PLEKHM2)

EFUS:

103292108(PLEKHM2)

MNA:	107531570(PLEKHM2)

DRO:	112298978(PLEKHM2)

SHON:

118986312(PLEKHM2)

AJM:	119049960(PLEKHM2)

PDIC:

114497750(PLEKHM2)

PHAS:

123831761(PLEKHM2)

MMF:	118626892(PLEKHM2)

PPAM:

129075633(PLEKHM2)

HAI:	109389405(PLEKHM2)

RFQ:	117026774(PLEKHM2)

PALE:

102878321(PLEKHM2)

PGIG:

120585772(PLEKHM2)

PVP:	105294410(PLEKHM2)

RAY:	107501805(PLEKHM2)

MJV:	108383579(PLEKHM2)

TOD:	119237276(PLEKHM2)

SARA:

101538329(PLEKHM2)

SFUM:

130031793(PLEKHM2)

SETR:

126006513(PLEKHM2)

LAV:	100655744(PLEKHM2)

TMU:

101357557

ETF:	101657311(PLEKHM2)

DNM:	101429300(PLEKHM2)

MDO:	100616740(PLEKHM2)

GAS:	123240976(PLEKHM2)

SHR:	100929917(PLEKHM2)

AFZ:

127555825

PCW:	110198779(PLEKHM2)

TVP:	118840341(PLEKHM2)

PBRV:

138154299(PLEKHM2)

MLAO:

141509103(PLEKHM2)

OAA:	100078780(PLEKHM2)

TACU:

119928783(PLEKHM2)

GGA:	419457(PLEKHM2)

PCOC:

116242651(PLEKHM2)

MGP:	100547807(PLEKHM2)

CJO:	107323411(PLEKHM2)

TPAI:

128084931(PLEKHM2)

LMUT:

125703318(PLEKHM2)

NMEL:

110408587

APLA:

101797517(PLEKHM2)

AACU:

137843280(PLEKHM2)

OJA:	118177091(PLEKHM2)

ACYG:

106048628(PLEKHM2)

CATA:

118258834(PLEKHM2)

AFUL:

116497652(PLEKHM2)

TGU:	100222637(PLEKHM2)

LSR:	110474456(PLEKHM2)

VMC:	128818400(PLEKHM2)

VCHA:

128798908(PLEKHM2)

AIB:	137461877(PLEKHM2)

SCAN:

103820965(PLEKHM2)

PMOA:

120496794(PLEKHM2)

OTC:	121343893(PLEKHM2)

PRUF:

121351328(PLEKHM2)

ATRC:

139600844(PLEKHM2)

MATE:

118694876(PLEKHM2)

MAEN:

136565325(PLEKHM2)

GFR:	102045597(PLEKHM2)

FAB:	101818078(PLEKHM2)

OMA:	130261731(PLEKHM2)

PHI:	102113637(PLEKHM2)

PMAJ:

107213542(PLEKHM2)

CCAE:

111938558(PLEKHM2)

CCW:	104698595(PLEKHM2)

CBRC:

103614546(PLEKHM2)

ACOE:

138121349(PLEKHM2)

ETL:	114068919(PLEKHM2)

ZAB:	102066344(PLEKHM2)

ZLE:	135456520(PLEKHM2)

ACHL:

103802505(PLEKHM2)

SVG:	106860524(PLEKHM2)

MMEA:

130581853(PLEKHM2)

HRT:	120762306(PLEKHM2)

SATI:

136370840(PLEKHM2)

CFAI:

136300411(PLEKHM2)

CCIC:

134052998(PLEKHM2)

FPG:	101921853(PLEKHM2)

FCH:	102054214(PLEKHM2)

FRS:	119144944(PLEKHM2)

CCRI:

104165064(PLEKHM2)

NNT:	104406653(PLEKHM2)

SHAB:

115617434(PLEKHM2)

ACUN:

113487822(PLEKHM2)

ANOC:

141969304(PLEKHM2)

SURA:

141953963(PLEKHM2)

TALA:

104368461(PLEKHM2)

ACHC:

115342446(PLEKHM2)

HALD:

104320269(PLEKHM2)

HLE:	104837987(PLEKHM2)

AGEN:

126041463

HHAR:

128144583(PLEKHM2)

BBUT:

142030985(PLEKHM2)

GCL:

127024793

CSTI:

104560208(PLEKHM2)

LDI:	104351021(PLEKHM2)

DPUB:

104309958(PLEKHM2)

PPUS:

135190368(PLEKHM2)

IIN:	128977496(PLEKHM2)

AVIT:

104272265(PLEKHM2)

EGZ:	104133119(PLEKHM2)

NNI:	104011191(PLEKHM2)

PCRI:

104028039(PLEKHM2)

PCAO:

104051909(PLEKHM2)

PARX:

142066551(PLEKHM2)

PADL:

103922242(PLEKHM2)

AFOR:

103907518(PLEKHM2)

FGA:	104073892(PLEKHM2)

CBOR:

142092203(PLEKHM2)

GSTE:

104264568(PLEKHM2)

CBOY:

140661546(PLEKHM2)

MAME:

142418560(PLEKHM2)

CLV:	102098305(PLEKHM2)

CNIC:

135997389(PLEKHM2)

MUI:	104537962(PLEKHM2)

PGUU:

104466350(PLEKHM2)

PLET:

104627310(PLEKHM2)

EHS:	104512404(PLEKHM2)

CUCA:

104065036(PLEKHM2)

PCUR:

138730083(PLEKHM2)

TEO:	104377978(PLEKHM2)

BREG:

104638240(PLEKHM2)

GAME:

129215901(PLEKHM2)

OHA:	104338994(PLEKHM2)

ACAR:

104523861(PLEKHM2)

CPEA:

104387055(PLEKHM2)

CVF:	104289416(PLEKHM2)

RTD:	128918357(PLEKHM2)

CRID:

134524103(PLEKHM2)

LMIC:

141732127(PLEKHM2)

NARQ:

141474011(PLEKHM2)

AAM:	106491385(PLEKHM2)

AROW:

112977492(PLEKHM2)

NPD:	112959644(PLEKHM2)

TGT:	104570497(PLEKHM2)

DNE:	112993477(PLEKHM2)

SCAM:

104141594(PLEKHM2)

ASN:	102379429(PLEKHM2)

AMJ:	102563090(PLEKHM2)

CPOO:

109314314(PLEKHM2)

GGN:	109293852(PLEKHM2)

PSS:	102461120(PLEKHM2)

CIZ:	142001029(PLEKHM2)

CMY:	102938730(PLEKHM2)

CCAY:

125624494(PLEKHM2)

LKP:	140900249(PLEKHM2)

NDS:	142000666(PLEKHM2)

DCC:	119844912(PLEKHM2)

CPIC:

101945764(PLEKHM2)

TST:	117867836(PLEKHM2)

EOB:	135893483(PLEKHM2)

CABI:

116829024(PLEKHM2)

MRV:	120387904(PLEKHM2)

ACS:	100556805(plekhm2)

ASAO:

132764786(PLEKHM2)

PVT:	110073170(PLEKHM2)

SUND:

121936105(PLEKHM2)

PBI:	103059033(PLEKHM2)

PMUR:

107296442(PLEKHM2)

CTIG:

120318950(PLEKHM2)

TSR:

106549987

PGUT:

117654735(PLEKHM2)

PCAE:

139326125(PLEKHM2)

APRI:

131187231(PLEKHM2)

PTEX:

113446294(PLEKHM2)

NSS:	113423151(PLEKHM2)

VKO:	123018824(PLEKHM2)

PMUA:

114602787(PLEKHM2)

PRAF:

128419902(PLEKHM2)

ZVI:	118086112(PLEKHM2)

HCG:	128338679(PLEKHM2)

GJA:	107111595(PLEKHM2)

STOW:

125445696(PLEKHM2)

EMC:	129344591(PLEKHM2)

XLA:	108696844(plekhm2.L) 108697857(plekhm2.S)

XTR:	100380102(plekhm2)

NPR:	108803587(PLEKHM2)

ACAT:

141111462(PLEKHM2)

PADS:

140341168(PLEKHM2)

BBUF:

120994684(PLEKHM2)

BGAR:

122929039(PLEKHM2)

DTC:	141085102(PLEKHM2)

PWL:	138300545(PLEKHM2)

MUO:	115482647(PLEKHM2)

GSH:	117349036(PLEKHM2)

DRE:	564823(plekhm2)

SRX:	107716120 107737546

SANH:

107673107 107687427

SGH:	107591088(plekhm2) 107593942

CCAR:

109047988 109093298(plekhm2)

CAUA:

113045593 113068907

CGIB:

127944793 128011975

PTET:

122328340(plekhm2)

LROH:

127154711(plekhm2)

GRF:	141290925(plekhm2)

OMC:	131531988(plekhm2)

PPRM:

120463467(plekhm2)

RKG:	130102124(plekhm2)

MAMB:

125260218(plekhm2)

CIDE:

127505087

CERY:

137009483(plekhm2)

MASI:

127418988 127420075

TROS:

130545240(plekhm2)

TDW:	130409290(plekhm2)

MANU:

129431075(plekhm2)

PDAB:

135775542(plekhm2)

IPU:

108275833

IFU:	128619491(plekhm2)

PHYP:

113530639(plekhm2)

TFD:	113658260(plekhm2)

TVC:	132861809(plekhm2)

CGAR:

128510528(plekhm2)

NGRA:

132897031(plekhm2)

TRN:	134333687(plekhm2)

AMEX:

103028132(plekhm2)

CMAO:

118822397(plekhm2)

EEE:	113580159(plekhm2)

CHAR:

105899045(plekhm2)

SPIL:

134087847(plekhm2)

ASAD:

121712991(plekhm2)

TRU:	101070649(plekhm2)

TFS:	130529456(plekhm2)

TNG:	GSTEN00020603G001

LCO:	104927140(plekhm2)

NCC:	104951589(plekhm2)

TBEN:

117494505(plekhm2)

CGOB:

115011044(plekhm2)

PGEO:

117449178(plekhm2)

GACU:

117532833(plekhm2)

EMAC:

134865823(plekhm2)

ELY:	117258508(plekhm2)

EFO:	125891647(plekhm2)

PLEP:

121946829(plekhm2)

SLUC:

116040651(plekhm2)

ECRA:

117947534(plekhm2)

ESP:	116692554(plekhm2)

PFLV:

114558478(plekhm2)

GAT:	120829304(plekhm2)

PPUG:

119222506(plekhm2)

AFB:	129099867(plekhm2)

CLUM:

117733204(plekhm2)

PSWI:

130199633(plekhm2)

CANA:

137800633(plekhm2)

CVE:	137889813(plekhm2)

MSAM:

119903269 119905884 119905893(plekhm2)

SCHU:

122883555(plekhm2)

EARM:

139289253(plekhm2)

CUD:	121517534(plekhm2)

SPUL:

138590232(plekhm2)

LMIX:

132989209(plekhm2)

HTC:	141799223(plekhm2)

ALAT:

119023237(plekhm2)

ASTR:

137605400(plekhm2)

PKLU:

139210144(plekhm2)

MZE:	101487243(plekhm2)

ONL:	100702841(plekhm2)

OAU:	116324481(plekhm2)

OLA:	101170394(plekhm2)

OML:	112151591(plekhm2)

CSAI:

133457409(plekhm2)

XMA:	102235579(plekhm2)

XCO:	114146858(plekhm2)

XHE:	116724579(plekhm2)

PRET:

103467019(plekhm2)

PFOR:

103150463(plekhm2)

PLAI:

106961941(plekhm2)

PMEI:

106926257(plekhm2)

GAF:	122832805(plekhm2)

PPRL:

129371774(plekhm2)

CVG:	107092905(plekhm2)

CTUL:

119792053(plekhm2)

GMU:	124869307(plekhm2)

NFU:	107390344(plekhm2)

KMR:	108233145(plekhm2)

ALIM:

106518932(plekhm2)

NWH:	119417135(plekhm2)

AOCE:

111564752(plekhm2)

EJA:	138192926(plekhm2)

BFRE:

138618337(plekhm2)

MCEP:

125019715(plekhm2)

CSEM:

103384788(plekhm2)

POV:	109630899(plekhm2)

SSEN:

122777388(plekhm2)

SSOE:

131468628(plekhm2)

HHIP:

117764897(plekhm2)

HSP:	118110975(plekhm2)

PPLT:

128442094(plekhm2)

SMAU:

118317420(plekhm2)

LCF:

108882593

SDU:	111227588(plekhm2)

SLAL:

111656221(plekhm2)

XGL:	120803623(plekhm2)

HCQ:	109528410(plekhm2)

SSCV:

125988221(plekhm2)

SBIA:

133496892(plekhm2)

PEE:	133412915(plekhm2)

PTAO:

133485848(plekhm2)

BPEC:

110157951(plekhm2)

ENY:	140363123(plekhm2)

MALB:

109967138(plekhm2)

BSPL:

114858757(plekhm2)

SJO:	128357197(plekhm2)

SSCO:

133987603(plekhm2)

TTY:	137184159(plekhm2)

GMH:	115547541(plekhm2)

SASA:

106566865 106572009

STRU:

115165868 115168199

OTW:	112222012(plekhm2) 112232569

OMY:	110492235(plekhm2) 110532374

OGO:	124032013 124045823(plekhm2)

ONE:	115102260 115132242

OKI:	109868960 109908067

OKE:	118359785 118360946

OMM:	135504329 135528153(plekhm2)

OCLA:

139368654 139416584

SALP:

111966537 111976539

SNH:	120059280 120061221(plekhm2)

SFON:

129830166 129860887(plekhm2)

CCLU:

121538430 121545570(plekhm2)

ELS:	105013698(plekhm2)

OEP:	134019291(plekhm2)

SFM:	108928220 108933860

PKI:	111853488 111853933

AANG:

118208173(plekhm2) 118210540

AROT:

135235332(plekhm2) 135237734

CCOG:

133110186 133139539(plekhm2)

LOC:	102687929(plekhm2)

PSPA:

121328665 121328708

ARUT:

117432317(plekhm2) 117963645

PSEX:

120530834(plekhm2)

LCM:	102347737(PLEKHM2)

CMK:	103187469(plekhm2)

RTP:	109917999(plekhm2)

CPLA:

122540099(plekhm2)

CPUN:

140487094(plekhm2)

HOC:	132833497(plekhm2)

SCAU:

119979427(plekhm2)

LERI:

129711492(plekhm2)

HAKA:

140718295(plekhm2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

APLC:

SKO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108721595(prd1)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139113096(Prd1)

TLN:	139811058(Prd1)

TAME:

143899585(Prd1)

HST:

DQU:

CFO:

FEX:

PMEC:

138933939(Prd1)

LHU:	105671841(prd1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

MDL:

CGLO:

CTYP:

141534264(Prd1)

FAS:

DAM:

CINS:

VCAN:

TCA:

TMOL:

138131795(prd1)

DPA:

109537418

ESIM:

136418293(prd1)

EFOR:

136348783(prd1)

RFG:	143192440(prd1)

ATD:

HAXR:

DVV:

NVL:

API:

DNX:

AGS:

RMD:

HHAL:

NLU:

PHU:	Phum_PHUM154970

FOC:

113202026

ZNE:

110827240

PAME:

138711240(prd1)

BROR:

134531894

IEL:

124163290

HAMR:

139696426(prd1)

DPX:	DAPPUDRAFT_110018

DMK:

DPZ:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

SDM:

LPOL:

TSP:

PCAN:

BGT:

GAE:

HRF:

HRJ:

HASI:

CRG:

MYI:

PMAX:

MMER:

OBI:

OSN:

LJP:

LAK:	106162538 106174380

NVE:

EPA:

ATEN:

PDAM:

SPIS:

DGT:

XEN:

HMG:

AQU:

MBR:	MONBRDRAFT_22573

SRE:	PTSG_00858

» show all

Reference

PMID:18996344

Authors

Ohlson MB, Huang Z, Alto NM, Blanc MP, Dixon JE, Chai J, Miller SI

Title

Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation.

Journal

Cell Host Microbe 4:434-46 (2008)
DOI:10.1016/j.chom.2008.08.012

Reference

PMID:15905402

Authors

Boucrot E, Henry T, Borg JP, Gorvel JP, Meresse S

Title

The intracellular fate of Salmonella depends on the recruitment of kinesin.

Journal

Science 308:1174-8 (2005)
DOI:10.1126/science.1110225

Sequence

[hsa:23207]

LinkDB

DBGET integrated database retrieval system