KEGG   ORTHOLOGY: K18364
Entry
K18364                      KO                                     
Symbol
bphH, xylJ, tesE
Name
2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
Pathway
map00362  Benzoate degradation
map00621  Dioxin degradation
map00622  Xylene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
   00622 Xylene degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
   00621 Dioxin degradation
    K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.80  2-oxopent-4-enoate hydratase
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
    4.2.1.132  2-hydroxyhexa-2,4-dienoate hydratase
     K18364  bphH, xylJ, tesE; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18364
Other DBs
RN: R02601 R05864
GO: 0008684 0034856
Genes
PGE: LG71_12240
PLUM: A4R40_11035
PAKH: B0X70_11350
PLUI: CE143_11265
PSD: DSC_09160 DSC_09365
RGL: CS053_01760
RTH: LRK53_10275(dmpE)
RBD: ALSL_1080
VAF: D1115_22450
PRE: PCA10_13820 PCA10_p0350(carD)
PPSE: BN5_3620(nahL)
PFUW: KF707C_12170 KF707C_15560(bzaF) KF707C_16070(salF) KF707C_16250(bphX1)
PCQ: PcP3B5_25700(tesE_1)
PPI: ND086(nahL)
PPUT: L483_14065
PPUN: PP4_27260
PPJ: RK21_04237
PVR: PverR02_11595 PverR02_14690
PSC: A458_06520
PSTU: UIB01_22740
PBM: CL52_14710
PPUU: PputUW4_01660(mhpD)
PKC: PKB_4239(xylJ)
PFZ: AV641_10535
PLQ: AA042_19765
PALK: PSAKL28_05940
PPSY: AOC04_07835
PFK: PFAS1_28775
PSET: THL1_1433
PSIL: PMA3_11735 PMA3_18070
PKE: DLD99_14750
PALL: UYA_06720 UYA_06980 UYA_07060 UYA_20155
PUM: HGP31_20760
PPSH: G5J76_13490
PLAL: FXN65_06420
PAZE: KSS91_19295
PALV: KSS97_16725
PPHA: BVH74_06155 BVH74_16350 BVH74_17960
PZA: HU749_013350
PTAE: NCTC10697_02057(xylJ)
AVN: Avin_08670(xylJ) Avin_30610(lapE)
AVL: AvCA_08670(xylJ) AvCA_30610(lapE)
AVD: AvCA6_08670(xylJ) AvCA6_30610(lapE)
ACX: Achr_32780
HPEG: EAO82_00555(dmpE) EAO82_09425(dmpE)
HAES: LO767_17670(dmpE)
MAD: HP15_1113 HP15_4034
MSR: AU15_21080
MLQ: ASQ50_09215
MSQ: BKP64_13850
MARJ: MARI_05440(xylJ)
SPL: Spea_2118
SHL: Shal_2090
SWD: Swoo_1392
COLW: A3Q33_18575
CBER: B5D82_11270
THT: E2K93_11200
PHA: PSHAa2141(xylJ)
PTN: PTRA_a2594(bphH)
PNG: PNIG_a2788(bphH)
SPOI: IMCC21906_00389 IMCC21906_02710
SNAN: I6N98_10800
ZAL: AZF00_03890 AZF00_11430 AZF00_17820
HJA: BST95_09505
HALC: EY643_13295
AFUS: EYZ66_02605(dmpE) EYZ66_12965
CYQ: Q91_0508
CZA: CYCME_2103
CYY: CPC19_10515(dmpE)
BLEP: AL038_01300(dmpE)
THIS: HZT40_10605
AEH: Mlg_2460
APAC: S7S_06990
KAK: Kalk_07855
MGEO: CFI10_00425(dmpE) CFI10_04960(dmpE)
MSEC: LN244_04775 LN244_11330(dmpE)
NCU: F0U83_03045(dmpE)
NJP: NEJAP_0671(mhpD)
NIK: F5I99_10105(dmpE) F5I99_10520(dmpE)
AJP: AMJAP_2999(mhpD)
ASIM: FE240_03500(dmpE)
ZDF: AN401_14585
SOK: D0B54_06200
SINI: GT972_13730(dmpE) GT972_14670
FCE: JN531_005830
GBI: PG2T_02230
TBN: TBH_C0928
GPB: HDN1F_27090(tesE)
NZO: SAMEA4504057_0450(xylJ)
NCI: NCTC10296_00911(xylJ_1)
NWD: H3L96_04745(dmpE)
NDU: LVJ88_00610(dmpE)
VFF: VITFI_CDS1370
PTES: JQU52_04880(dmpE)
USU: LVJ78_03680(dmpE)
CHRO: CXB49_03840
AQL: BXU06_16875
RPI: Rpic_4620
RPF: Rpic12D_3544
RPJ: N234_08150 N234_12215
RIN: ACS15_4354(dmpE)
REH: H16_B0548(mhpD1) H16_B0597(bphH)
CNC: CNE_2c04940(mhpD) CNE_2c05420(xylJ2) CNE_BB1p11990(xylJ1) CNE_BB1p13280(xylJ2)
CUH: BJN34_30960
REU: Reut_A1510 Reut_B5691
RME: Rmet_1321(xylJ)
CTI: RALTA_B0401(mhpD)
CBW: RR42_s2313 RR42_s2484
CCUP: BKK81_19910 BKK81_27090
CUP: BKK80_21900 BKK80_29230
CUU: BKK79_35180
COX: E0W60_07775(dmpE) E0W60_08025(dmpE)
BVI: Bcep1808_7603
BUR: Bcep18194_B1459 Bcep18194_B2961
BCJ: BCAM1613
BCEN: DM39_3383(dmpE) DM39_4834(dmpE)
BCEO: I35_5473
BCT: GEM_4111 GEM_5403
BCED: DM42_4993(dmpE) DM42_6345(dmpE)
BCEP: APZ15_31155
BPYR: ABD05_27820
BCON: NL30_04140 NL30_24600
BDF: WI26_15985 WI26_21145
BTEI: WS51_00560 WS51_05695
BPSL: WS57_06045 WS57_12165
BMEC: WJ16_26790
BSTL: BBJ41_10510 BBJ41_21340
BANN: JFN94_19125(dmpE) JFN94_25650(dmpE)
BUQ: AC233_11195
BURK: DM992_32625(dmpE)
BXE: Bxe_C1189(bphH)
BXB: DR64_8616(dmpE)
BUZ: AYM40_21220
BFN: OI25_4589(dmpE)
PARB: CJU94_37870(dmpE) CJU94_38115(dmpE)
PCAF: DSC91_003291
PMEG: FNZ07_21165(dmpE)
PPK: U875_01900
PRB: X636_07570
PVE: UC34_07065
CABA: SBC2_49020(tesE)
LIMN: HKT17_03820(dmpE)
BOJ: CBF45_01490 CBF45_04500 CBF45_06955
CDN: BN940_01166 BN940_04316
KGY: EHF36_01675(dmpE) EHF36_04885(dmpE)
PNA: Pnap_4144
AJS: Ajs_0222
ACID: CBP33_01105
ACIP: CBP36_01200
ACIN: CBP34_01110
ACIS: CBP35_17750
AMON: H9L24_14185(dmpE)
VEI: Veis_2785
VBO: CKY39_28505(dmpE)
CTT: CtCNB1_1353 CtCNB1_3149
CTES: O987_07740
COF: FOZ74_08305(dmpE)
ADN: Alide_0337
ADK: Alide2_0282
HYL: LPB072_18180
HPSE: HPF_01870(xylJ)
HYN: F9K07_02750(dmpE)
HTN: KI616_01965(dmpE)
DIH: G7047_01670(dmpE) G7047_09705
DRG: H9K76_11645(dmpE)
SIMP: C6571_13615(dmpE)
MELA: C6568_07860(dmpE)
MJE: LVC68_01005(dmpE)
STHM: IS481_10530(dmpE)
MPT: Mpe_A2273 Mpe_A3325
METP: C1M51_06460(dmpE) C1M51_15400(dmpE)
JAG: GJA_236(xylJ)
JAJ: EKL02_01815(dmpE)
MASW: AM586_18650
LCH: Lcho_3343
SNN: EWH46_19325
IDC: LRM40_19570(dmpE)
RBU: PG1C_14105
ABRE: pbN1_20560(mhpD)
DAR: Daro_2774 Daro_3785
DEY: HYN24_14130(dmpE) HYN24_14215(dmpE)
FLE: KI610_08575(dmpE) KI610_13420(dmpE) KI610_15465(dmpE)
AZO: azo1853(lapE) azo2434(nahL)
AOA: dqs_2006 dqs_2578
AZI: AzCIB_1507 AzCIB_4411
AZD: CDA09_09955 CDA09_10325(dmpE) CDA09_10440(dmpE) CDA09_21440(dmpE)
AZR: CJ010_12250(dmpE) CJ010_15220(dmpE)
TMZ: Tmz1t_2077 Tmz1t_3091
THU: AC731_001810 AC731_008895
THK: CCZ27_10770(dmpE) CCZ27_16275(dmpE)
AZQ: G3580_00535(dmpE) G3580_08270(dmpE)
ACIB: ACBT_0261(dmpE)
AFC: AFAEC_1846(dmpE)
AAQI: AAQM_0980(dmpE)
ACLO: ACLO_a0141(dmpE)
ADZ: ADFLV_2553(dmpE)
ALK: ALEK_0381(dmpE)
AANA: AANAER_1258(dmpE)
ARC: ABLL_2444
NTD: EGO55_13680
TEC: AKL02_008255
NAR: Saro_3689
NPP: PP1Y_AT32745 PP1Y_Mpl3103
NPN: JI59_22525
NOV: TQ38_027295
NOT: C7W88_20925
SGI: SGRAN_1581(mhpD)
SPHM: G432_01985
SSAN: NX02_12710
SPKC: KC8_03560
SPHA: D3Y57_15215
SLAN: GV829_01855
SJP: SJA_C1-11870(mhpD)
SINB: SIDU_08330
SYB: TZ53_09010 TZ53_23455
SPHB: EP837_03394(bphH)
SHYD: CJD35_06490
SUFL: FIL70_19005
SBAR: H5V43_20655
SFLA: SPHFLASMR4Y_02368(tesE)
SPHJ: BSL82_10455
PALG: HFP57_16665
PHAO: HF685_05520
TFV: IDJ81_04970
PHZ: CHX26_05320
PEG: E5R92_01705
HTL: HPTL_0050
ASED: IRT44_17630
MHAP: JFY71_09925
CWO: Cwoe_3997
AMOB: HG15A2_23830(tesE)
NAY: HYG81_22605
AG: BAC67694(tesE)
 » show all
Reference
PMID:16151114
  Authors
Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T
  Title
Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.
  Journal
Appl Environ Microbiol 71:5275-81 (2005)
DOI:10.1128/AEM.71.9.5275-5281.2005
  Sequence
[ag:BAC67694]
LinkDB

KEGG   ENZYME: 4.2.1.132
Entry
EC 4.2.1.132                Enzyme                                 
Name
2-hydroxyhexa-2,4-dienoate hydratase;
tesE (gene name);
hsaE (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
4-hydroxy-2-oxohexanoate hydro-lyase [(2Z,4Z)-2-hydroxyhexa-2,4-dienoate-forming]
Reaction(IUBMB)
4-hydroxy-2-oxohexanoate = (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H2O [RN:R09960]
Reaction(KEGG)
R09960;
(other) R05864
Substrate
4-hydroxy-2-oxohexanoate [CPD:C06762]
Product
(2Z,4Z)-2-hydroxyhexa-2,4-dienoate [CPD:C20240];
H2O [CPD:C00001]
Comment
This enzyme catalyses a late step in the bacterial steroid degradation pathway. The product, 4-hydroxy-2-oxohexanoate, forms a 2-hydroxy-4-hex-2-enolactone under acidic conditions.
History
EC 4.2.1.132 created 2012
Pathway
ec00622  Xylene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18364  2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase
Genes
PGE: LG71_12240
PLUM: A4R40_11035
PAKH: B0X70_11350
PLUI: CE143_11265
PSD: DSC_09160 DSC_09365
RGL: CS053_01760
RTH: LRK53_10275(dmpE)
RBD: ALSL_1080
VAF: D1115_22450
PRE: PCA10_13820 PCA10_p0350(carD)
PPSE: BN5_3620(nahL)
PFUW: KF707C_12170 KF707C_15560(bzaF) KF707C_16070(salF) KF707C_16250(bphX1)
PCQ: PcP3B5_25700(tesE_1)
PPI: ND086(nahL)
PPUT: L483_14065
PPUN: PP4_27260
PPJ: RK21_04237
PVR: PverR02_11595 PverR02_14690
PSC: A458_06520
PSTU: UIB01_22740
PBM: CL52_14710
PPUU: PputUW4_01660(mhpD)
PKC: PKB_4239(xylJ)
PFZ: AV641_10535
PLQ: AA042_19765
PALK: PSAKL28_05940
PPSY: AOC04_07835
PFK: PFAS1_28775
PSET: THL1_1433
PSIL: PMA3_11735 PMA3_18070
PKE: DLD99_14750
PALL: UYA_06720 UYA_06980 UYA_07060 UYA_20155
PUM: HGP31_20760
PPSH: G5J76_13490
PLAL: FXN65_06420
PAZE: KSS91_19295
PALV: KSS97_16725
PPHA: BVH74_06155 BVH74_16350 BVH74_17960
PZA: HU749_013350
PTAE: NCTC10697_02057(xylJ)
AVN: Avin_08670(xylJ) Avin_30610(lapE)
AVL: AvCA_08670(xylJ) AvCA_30610(lapE)
AVD: AvCA6_08670(xylJ) AvCA6_30610(lapE)
ACX: Achr_32780
HPEG: EAO82_00555(dmpE) EAO82_09425(dmpE)
HAES: LO767_17670(dmpE)
MAD: HP15_1113 HP15_4034
MSR: AU15_21080
MLQ: ASQ50_09215
MSQ: BKP64_13850
MARJ: MARI_05440(xylJ)
SPL: Spea_2118
SHL: Shal_2090
SWD: Swoo_1392
COLW: A3Q33_18575
CBER: B5D82_11270
THT: E2K93_11200
PHA: PSHAa2141(xylJ)
PTN: PTRA_a2594(bphH)
PNG: PNIG_a2788(bphH)
SPOI: IMCC21906_00389 IMCC21906_02710
SNAN: I6N98_10800
ZAL: AZF00_03890 AZF00_11430 AZF00_17820
HJA: BST95_09505
HALC: EY643_13295
AFUS: EYZ66_02605(dmpE) EYZ66_12965
CYQ: Q91_0508
CZA: CYCME_2103
CYY: CPC19_10515(dmpE)
BLEP: AL038_01300(dmpE)
THIS: HZT40_10605
AEH: Mlg_2460
APAC: S7S_06990
KAK: Kalk_07855
MGEO: CFI10_00425(dmpE) CFI10_04960(dmpE)
MSEC: LN244_04775 LN244_11330(dmpE)
NCU: F0U83_03045(dmpE)
NJP: NEJAP_0671(mhpD)
NIK: F5I99_10105(dmpE) F5I99_10520(dmpE)
AJP: AMJAP_2999(mhpD)
ASIM: FE240_03500(dmpE)
ZDF: AN401_14585
SOK: D0B54_06200
SINI: GT972_13730(dmpE) GT972_14670
FCE: JN531_005830
GBI: PG2T_02230
TBN: TBH_C0928
GPB: HDN1F_27090(tesE)
NZO: SAMEA4504057_0450(xylJ)
NCI: NCTC10296_00911(xylJ_1)
NWD: H3L96_04745(dmpE)
NDU: LVJ88_00610(dmpE)
VFF: VITFI_CDS1370
PTES: JQU52_04880(dmpE)
USU: LVJ78_03680(dmpE)
CHRO: CXB49_03840
AQL: BXU06_16875
RPI: Rpic_4620
RPF: Rpic12D_3544
RPJ: N234_08150 N234_12215
RIN: ACS15_4354(dmpE)
REH: H16_B0548(mhpD1) H16_B0597(bphH)
CNC: CNE_2c04940(mhpD) CNE_2c05420(xylJ2) CNE_BB1p11990(xylJ1) CNE_BB1p13280(xylJ2)
CUH: BJN34_30960
REU: Reut_A1510 Reut_B5691
RME: Rmet_1321(xylJ)
CTI: RALTA_B0401(mhpD)
CBW: RR42_s2313 RR42_s2484
CCUP: BKK81_19910 BKK81_27090
CUP: BKK80_21900 BKK80_29230
CUU: BKK79_35180
COX: E0W60_07775(dmpE) E0W60_08025(dmpE)
BVI: Bcep1808_7603
BUR: Bcep18194_B1459 Bcep18194_B2961
BCJ: BCAM1613
BCEN: DM39_3383(dmpE) DM39_4834(dmpE)
BCEO: I35_5473
BCT: GEM_4111 GEM_5403
BCED: DM42_4993(dmpE) DM42_6345(dmpE)
BCEP: APZ15_31155
BPYR: ABD05_27820
BCON: NL30_04140 NL30_24600
BDF: WI26_15985 WI26_21145
BTEI: WS51_00560 WS51_05695
BPSL: WS57_06045 WS57_12165
BMEC: WJ16_26790
BSTL: BBJ41_10510 BBJ41_21340
BANN: JFN94_19125(dmpE) JFN94_25650(dmpE)
BUQ: AC233_11195
BURK: DM992_32625(dmpE)
BXE: Bxe_C1189(bphH)
BXB: DR64_8616(dmpE)
BUZ: AYM40_21220
BFN: OI25_4589(dmpE)
PARB: CJU94_37870(dmpE) CJU94_38115(dmpE)
PCAF: DSC91_003291
PMEG: FNZ07_21165(dmpE)
PPK: U875_01900
PRB: X636_07570
PVE: UC34_07065
CABA: SBC2_49020(tesE)
LIMN: HKT17_03820(dmpE)
BOJ: CBF45_01490 CBF45_04500 CBF45_06955
CDN: BN940_01166 BN940_04316
KGY: EHF36_01675(dmpE) EHF36_04885(dmpE)
PNA: Pnap_4144
AJS: Ajs_0222
ACID: CBP33_01105
ACIP: CBP36_01200
ACIN: CBP34_01110
ACIS: CBP35_17750
AMON: H9L24_14185(dmpE)
VEI: Veis_2785
VBO: CKY39_28505(dmpE)
CTT: CtCNB1_1353 CtCNB1_3149
CTES: O987_07740
COF: FOZ74_08305(dmpE)
ADN: Alide_0337
ADK: Alide2_0282
HYL: LPB072_18180
HPSE: HPF_01870(xylJ)
HYN: F9K07_02750(dmpE)
HTN: KI616_01965(dmpE)
DIH: G7047_01670(dmpE) G7047_09705
DRG: H9K76_11645(dmpE)
SIMP: C6571_13615(dmpE)
MELA: C6568_07860(dmpE)
MJE: LVC68_01005(dmpE)
STHM: IS481_10530(dmpE)
MPT: Mpe_A2273 Mpe_A3325
METP: C1M51_06460(dmpE) C1M51_15400(dmpE)
JAG: GJA_236(xylJ)
JAJ: EKL02_01815(dmpE)
MASW: AM586_18650
LCH: Lcho_3343
SNN: EWH46_19325
IDC: LRM40_19570(dmpE)
RBU: PG1C_14105
ABRE: pbN1_20560(mhpD)
DAR: Daro_2774 Daro_3785
DEY: HYN24_14130(dmpE) HYN24_14215(dmpE)
FLE: KI610_08575(dmpE) KI610_13420(dmpE) KI610_15465(dmpE)
AZO: azo1853(lapE) azo2434(nahL)
AOA: dqs_2006 dqs_2578
AZI: AzCIB_1507 AzCIB_4411
AZD: CDA09_09955 CDA09_10325(dmpE) CDA09_10440(dmpE) CDA09_21440(dmpE)
AZR: CJ010_12250(dmpE) CJ010_15220(dmpE)
TMZ: Tmz1t_2077 Tmz1t_3091
THU: AC731_001810 AC731_008895
THK: CCZ27_10770(dmpE) CCZ27_16275(dmpE)
AZQ: G3580_00535(dmpE) G3580_08270(dmpE)
ACIB: ACBT_0261(dmpE)
AFC: AFAEC_1846(dmpE)
AAQI: AAQM_0980(dmpE)
ACLO: ACLO_a0141(dmpE)
ADZ: ADFLV_2553(dmpE)
ALK: ALEK_0381(dmpE)
AANA: AANAER_1258(dmpE)
ARC: ABLL_2444
NTD: EGO55_13680
TEC: AKL02_008255
NAR: Saro_3689
NPP: PP1Y_AT32745 PP1Y_Mpl3103
NPN: JI59_22525
NOV: TQ38_027295
NOT: C7W88_20925
SGI: SGRAN_1581(mhpD)
SPHM: G432_01985
SSAN: NX02_12710
SPKC: KC8_03560
SPHA: D3Y57_15215
SLAN: GV829_01855
SJP: SJA_C1-11870(mhpD)
SINB: SIDU_08330
SYB: TZ53_09010 TZ53_23455
SPHB: EP837_03394(bphH)
SHYD: CJD35_06490
SUFL: FIL70_19005
SBAR: H5V43_20655
SFLA: SPHFLASMR4Y_02368(tesE)
SPHJ: BSL82_10455
PALG: HFP57_16665
PHAO: HF685_05520
TFV: IDJ81_04970
PHZ: CHX26_05320
PEG: E5R92_01705
HTL: HPTL_0050
ASED: IRT44_17630
MHAP: JFY71_09925
CWO: Cwoe_3997
AMOB: HG15A2_23830(tesE)
NAY: HYG81_22605
 » show all
Reference
1  [PMID:16151114]
  Authors
Horinouchi M, Hayashi T, Koshino H, Kurita T, Kudo T
  Title
Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441.
  Journal
Appl Environ Microbiol 71:5275-81 (2005)
DOI:10.1128/AEM.71.9.5275-5281.2005
  Sequence
[ag:BAC67694]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.132
IUBMB Enzyme Nomenclature: 4.2.1.132
ExPASy - ENZYME nomenclature database: 4.2.1.132
UM-BBD (Biocatalysis/Biodegradation Database): 4.2.1.132
BRENDA, the Enzyme Database: 4.2.1.132
LinkDB

KEGG   REACTION: R05864
Entry
R05864                      Reaction                               
Name
4-Hydroxy-2-oxohexanoate hydro-lyase
Definition
2-Hydroxy-cis-hex-2,4-dienoate + H2O <=> 4-Hydroxy-2-oxohexanoic acid
Equation
C11354 + C00001 <=> C06762
Reaction class
RC02676  C06762_C11354
Enzyme
4.2.1.132
Pathway
rn00622  Xylene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Orthology
K18364  2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
LinkDB

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